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The map label for this gene is engD [H]

Identifier: 169824070

GI number: 169824070

Start: 425542

End: 426639

Strand: Direct

Name: engD [H]

Synonym: FMG_0373

Alternate gene names: 169824070

Gene position: 425542-426639 (Clockwise)

Preceding gene: 169824069

Following gene: 169824071

Centisome position: 23.67

GC content: 34.43

Gene sequence:

>1098_bases
ATGAAATTAGGTATTGTGGGGCTTCCAAATGTAGGAAAGTCTACACTTTTTAATGCGATAACAAAAGCAGGTGCAGAAAT
GGCAAATTATCCATTCTGTACAATAGATCCTAACATCGGACTTGTAAATGTTCCTGATGAAAGAGTGTATAAATTAGCAG
AACTTTTTAATTCAAAAAAAATTATTCCAGCTACTATTGAATTTTACGACATTGCAGGCCTTGTAAAAGGCGCAAGCAAG
GGTGAAGGTTTGGGAAATAAATTTTTGGAAAATATTAGAGAATCCGATGCTATTGTTGAAGTTCTAAGATGTTTTGAAGA
CGAAAACATAGTTCACGTTGATGGTTCTGTGGATCCTATTAGAGATATCGAAACTATCAACTATGAGCTTATTTTATCTG
ACTTGGAAATGGTTGAAAGAAGATTAGAAAAATCCAGAAAAGCTTTGAAAGGTAATAAGGATTTGAAGGAAGAAGTGGAT
CTTCTTGAAAAAATTTACGAAGTTTTATCTGAAGGAAAATCAATCAGAATTTTGGATTTGGACGAAGATGAAATGAAACT
TATGAGAAGTTTCAATCTTTTGAGCGTAAAGCCAATAATTTATGTCTGCAATGTAAGTGAAGATGAAGTAGCGGATGCTT
ACGAAAACAACGAAATGGTTCAAAAAGTAAAAGAGTTCGCAAAATCAGAAGATGCAAAAGTAGTTGTAATCTCTGCACAA
ATTGAATCGGAAATTTCTGCATTGGATAGCGAAGAAGACAAGAAAGAATTCTTGGAAGCAATTGGTCTTGAAAAATCAGG
AATCGACGATTTGATTACACAAAGCTATGATTTATTGGGACTTATGAGTTTCTTGACAACAGGAGAAGACGAAACTCGTG
CATGGACAATCAAGAAAAACACTCCTGCAGTACAAGCAGCTGGTAAAATCCACACAGATATTCAAAGAGGATTCATCAGA
GCAGAAATTGTAAACTACGATGATTTAATCGAATTAAAATCTATGGCTGCAGTCAGAGAAAAAGGCCTTATGAGATTGGA
AGGCAAAGAATATTTGATGCAAGACGGAGATGTAGTTCATTTTAGATTTAACGTATAG

Upstream 100 bases:

>100_bases
TTTAAATTAGAGCTCTGAAAAGAGCTCTTTTTGAATGTGTATAATTTACAAAAAATATGGTATATGGTAAAATTTGAGTT
AGTTAAAAGGAGTGAATGAT

Downstream 100 bases:

>100_bases
AAAAGATTTAATGTAGTAAAAAATCAATTATTGGTTTTGATTTTTTGTTTAACATATTTTACAAACTAGGTATTAATTTA
CCTAGTTTTTTTGTTAGCGT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKLGIVGLPNVGKSTLFNAITKAGAEMANYPFCTIDPNIGLVNVPDERVYKLAELFNSKKIIPATIEFYDIAGLVKGASK
GEGLGNKFLENIRESDAIVEVLRCFEDENIVHVDGSVDPIRDIETINYELILSDLEMVERRLEKSRKALKGNKDLKEEVD
LLEKIYEVLSEGKSIRILDLDEDEMKLMRSFNLLSVKPIIYVCNVSEDEVADAYENNEMVQKVKEFAKSEDAKVVVISAQ
IESEISALDSEEDKKEFLEAIGLEKSGIDDLITQSYDLLGLMSFLTTGEDETRAWTIKKNTPAVQAAGKIHTDIQRGFIR
AEIVNYDDLIELKSMAAVREKGLMRLEGKEYLMQDGDVVHFRFNV

Sequences:

>Translated_365_residues
MKLGIVGLPNVGKSTLFNAITKAGAEMANYPFCTIDPNIGLVNVPDERVYKLAELFNSKKIIPATIEFYDIAGLVKGASK
GEGLGNKFLENIRESDAIVEVLRCFEDENIVHVDGSVDPIRDIETINYELILSDLEMVERRLEKSRKALKGNKDLKEEVD
LLEKIYEVLSEGKSIRILDLDEDEMKLMRSFNLLSVKPIIYVCNVSEDEVADAYENNEMVQKVKEFAKSEDAKVVVISAQ
IESEISALDSEEDKKEFLEAIGLEKSGIDDLITQSYDLLGLMSFLTTGEDETRAWTIKKNTPAVQAAGKIHTDIQRGFIR
AEIVNYDDLIELKSMAAVREKGLMRLEGKEYLMQDGDVVHFRFNV
>Mature_365_residues
MKLGIVGLPNVGKSTLFNAITKAGAEMANYPFCTIDPNIGLVNVPDERVYKLAELFNSKKIIPATIEFYDIAGLVKGASK
GEGLGNKFLENIRESDAIVEVLRCFEDENIVHVDGSVDPIRDIETINYELILSDLEMVERRLEKSRKALKGNKDLKEEVD
LLEKIYEVLSEGKSIRILDLDEDEMKLMRSFNLLSVKPIIYVCNVSEDEVADAYENNEMVQKVKEFAKSEDAKVVVISAQ
IESEISALDSEEDKKEFLEAIGLEKSGIDDLITQSYDLLGLMSFLTTGEDETRAWTIKKNTPAVQAAGKIHTDIQRGFIR
AEIVNYDDLIELKSMAAVREKGLMRLEGKEYLMQDGDVVHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=371, Percent_Identity=43.9353099730458, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI58761502, Length=219, Percent_Identity=37.4429223744292, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24308117, Length=169, Percent_Identity=29.585798816568, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=50.8196721311475, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1789574, Length=199, Percent_Identity=29.6482412060301, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=41.8478260869565, Blast_Score=294, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=41.4438502673797, Blast_Score=275, Evalue=6e-75,
Organism=Saccharomyces cerevisiae, GI6321773, Length=386, Percent_Identity=37.8238341968912, Blast_Score=249, Evalue=7e-67,
Organism=Saccharomyces cerevisiae, GI6321649, Length=292, Percent_Identity=29.4520547945205, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321962, Length=101, Percent_Identity=35.6435643564356, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=39.6739130434783, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=39.6739130434783, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=39.6739130434783, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=37.6146788990826, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24585318, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 41029; Mature: 41029

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGIVGLPNVGKSTLFNAITKAGAEMANYPFCTIDPNIGLVNVPDERVYKLAELFNSKK
CCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHHHHCCCC
IIPATIEFYDIAGLVKGASKGEGLGNKFLENIRESDAIVEVLRCFEDENIVHVDGSVDPI
CCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RDIETINYELILSDLEMVERRLEKSRKALKGNKDLKEEVDLLEKIYEVLSEGKSIRILDL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
DEDEMKLMRSFNLLSVKPIIYVCNVSEDEVADAYENNEMVQKVKEFAKSEDAKVVVISAQ
CHHHHHHHHHCCCEEECCEEEEEECCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEH
IESEISALDSEEDKKEFLEAIGLEKSGIDDLITQSYDLLGLMSFLTTGEDETRAWTIKKN
HHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
TPAVQAAGKIHTDIQRGFIRAEIVNYDDLIELKSMAAVREKGLMRLEGKEYLMQDGDVVH
CCCHHHCCHHHHHHHHCHHHHEECCHHHHHHHHHHHHHHHCCCEEECCHHHHHCCCCEEE
FRFNV
EEECC
>Mature Secondary Structure
MKLGIVGLPNVGKSTLFNAITKAGAEMANYPFCTIDPNIGLVNVPDERVYKLAELFNSKK
CCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHHHHCCCC
IIPATIEFYDIAGLVKGASKGEGLGNKFLENIRESDAIVEVLRCFEDENIVHVDGSVDPI
CCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
RDIETINYELILSDLEMVERRLEKSRKALKGNKDLKEEVDLLEKIYEVLSEGKSIRILDL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
DEDEMKLMRSFNLLSVKPIIYVCNVSEDEVADAYENNEMVQKVKEFAKSEDAKVVVISAQ
CHHHHHHHHHCCCEEECCEEEEEECCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEH
IESEISALDSEEDKKEFLEAIGLEKSGIDDLITQSYDLLGLMSFLTTGEDETRAWTIKKN
HHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
TPAVQAAGKIHTDIQRGFIRAEIVNYDDLIELKSMAAVREKGLMRLEGKEYLMQDGDVVH
CCCHHHCCHHHHHHHHCHHHHEECCHHHHHHHHHHHHHHHCCCEEECCHHHHHCCCCEEE
FRFNV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]