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The map label for this gene is lolC [H]

Identifier: 167623546

GI number: 167623546

Start: 1940960

End: 1942183

Strand: Direct

Name: lolC [H]

Synonym: Shal_1615

Alternate gene names: 167623546

Gene position: 1940960-1942183 (Clockwise)

Preceding gene: 167623542

Following gene: 167623547

Centisome position: 37.13

GC content: 48.69

Gene sequence:

>1224_bases
ATGAATTTTTCATTATCGTTTTATATTGGTTATCGCTACTGGCGAGCACGTAAATCCAATGCATTTGCATCATTTATTAC
CATCTTTGCCGTCTCTGGAATTTTACTCGGTGTCGCAGCACTCATTGTGGTCAGCTCTGTTATGAACGGCCTTGAAGGGC
AGCTTAAACAGCGGATCTTAGGTGCCGTGCCGCAATTAACCGTGCATTCGCAAACCGCGATTGTTGATTGGCCTGAACAA
GTCGCCAAGCTGAACGGGCTTCCCGGCATCATTGGCGCGACCCCCAGTATCACTACTCAAGCCATGGTGCAATCGCCGAG
TAATATTGGCGCTGCGCAGATTTATGGGATCTATCCAGAGCAGGAAAAAAGCTTACCCAATACTACAAAGCAGGTTTATT
CCGGTGATTTTGATGCACTAGAGTCTGGAAAATATCGCATTATTTTAGGCGCGGAACTCGCTCGAATGCTCGATGTTGTC
CCCGGGGATAAAATTCGCGTGCTGAGCGGCGATGGCGTGGTGTATACACCACTTGGCCCAGTGCCAAGCCAGCGCAAGTT
TACCGTGGCTGGCGTATTTGAGATGGGTTCACAAGTGGACGCTACGCTTGCCTATGTCCATCATGATGACGCTCAGCGCT
TGATGAGACAAAAAGCAGGTGAAATTAAAGAGTTGCGCTTGTATCTAGATGATCCTTTTAACGCCGCTAAAATAGCGCCT
GAAGTGATTGACCAATTTGCCGTGCCTGTGACTACAACGGATTGGCGTGACACTTACGGCCACCTGTTCGGCGCGGTTAA
GATGGAAAAGAACATGATGTCTTTAATGCTCAGCCTGATTATCGCCGTTGCCGCATTCAATATTGTCTCTGCCTTGGTGA
TGATGGTGGTTGATAAAACCACTGACGTTGCCGTGCTCAAGACTCAAGGCTTAACGACAGCAAATGTGATGGGGATTTTT
ATGATCCAAGGCTCGCTCAATGCTGTTATCGGCCTCATCTCCGGTGTGGCGGTCGGTACTTTGCTAACCCTTAACTTAAA
CACCATCACTCAGGCACTTGGGATCTCCATCTTAGGAGCAGGTCAAAATTTACCTGTGCAGCTTGAACTAAGCCAGCTGA
CGTGGATTGTAGTCGGTACATTAGTGATCACGCTGGTTGCCACCGTTTACCCCGCAATTAGAGCGGCGAATGTGCAGCCT
GCTACCGCGCTTAGATATGAGTAG

Upstream 100 bases:

>100_bases
CGAAGCGCTGGGGATCTGTTATCCCATTTTAATGGGGGCTAGCCAGTTAATTACCATGGCTATCGAGCTCAGCTTAAGTC
GATTATATTTGGGTTTTTTA

Downstream 100 bases:

>100_bases
CAAGGATACGAGTAGCGGATATGACTAAGAACAGAATAAGTTACAATAGCGAGTTAACAATGAATCAAGAATTATTGCTA
CAAGTCAGTGGTGTCAGCAA

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNFSLSFYIGYRYWRARKSNAFASFITIFAVSGILLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTVHSQTAIVDWPEQ
VAKLNGLPGIIGATPSITTQAMVQSPSNIGAAQIYGIYPEQEKSLPNTTKQVYSGDFDALESGKYRIILGAELARMLDVV
PGDKIRVLSGDGVVYTPLGPVPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEIKELRLYLDDPFNAAKIAP
EVIDQFAVPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKTTDVAVLKTQGLTTANVMGIF
MIQGSLNAVIGLISGVAVGTLLTLNLNTITQALGISILGAGQNLPVQLELSQLTWIVVGTLVITLVATVYPAIRAANVQP
ATALRYE

Sequences:

>Translated_407_residues
MNFSLSFYIGYRYWRARKSNAFASFITIFAVSGILLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTVHSQTAIVDWPEQ
VAKLNGLPGIIGATPSITTQAMVQSPSNIGAAQIYGIYPEQEKSLPNTTKQVYSGDFDALESGKYRIILGAELARMLDVV
PGDKIRVLSGDGVVYTPLGPVPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEIKELRLYLDDPFNAAKIAP
EVIDQFAVPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKTTDVAVLKTQGLTTANVMGIF
MIQGSLNAVIGLISGVAVGTLLTLNLNTITQALGISILGAGQNLPVQLELSQLTWIVVGTLVITLVATVYPAIRAANVQP
ATALRYE
>Mature_407_residues
MNFSLSFYIGYRYWRARKSNAFASFITIFAVSGILLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTVHSQTAIVDWPEQ
VAKLNGLPGIIGATPSITTQAMVQSPSNIGAAQIYGIYPEQEKSLPNTTKQVYSGDFDALESGKYRIILGAELARMLDVV
PGDKIRVLSGDGVVYTPLGPVPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEIKELRLYLDDPFNAAKIAP
EVIDQFAVPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKTTDVAVLKTQGLTTANVMGIF
MIQGSLNAVIGLISGVAVGTLLTLNLNTITQALGISILGAGQNLPVQLELSQLTWIVVGTLVITLVATVYPAIRAANVQP
ATALRYE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=406, Percent_Identity=41.871921182266, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI1787362, Length=420, Percent_Identity=33.0952380952381, Blast_Score=184, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43747; Mature: 43747

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSLSFYIGYRYWRARKSNAFASFITIFAVSGILLGVAALIVVSSVMNGLEGQLKQRIL
CCEEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTVHSQTAIVDWPEQVAKLNGLPGIIGATPSITTQAMVQSPSNIGAAQIYGIYPE
HCCCCEEECCCEEEEECHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCC
QEKSLPNTTKQVYSGDFDALESGKYRIILGAELARMLDVVPGDKIRVLSGDGVVYTPLGP
HHCCCCCHHHHHHCCCHHHHCCCCEEEEECHHHHHHHHCCCCCEEEEEECCCEEECCCCC
VPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEIKELRLYLDDPFNAAKIAP
CCCCCEEEEEEHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCHHHCCH
EVIDQFAVPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDVAVLKTQGLTTANVMGIFMIQGSLNAVIGLISGVAVGTLLTLNLNTITQALGISILGA
CCEEEEEECCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHCCEEEEC
GQNLPVQLELSQLTWIVVGTLVITLVATVYPAIRAANVQPATALRYE
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNFSLSFYIGYRYWRARKSNAFASFITIFAVSGILLGVAALIVVSSVMNGLEGQLKQRIL
CCEEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTVHSQTAIVDWPEQVAKLNGLPGIIGATPSITTQAMVQSPSNIGAAQIYGIYPE
HCCCCEEECCCEEEEECHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCC
QEKSLPNTTKQVYSGDFDALESGKYRIILGAELARMLDVVPGDKIRVLSGDGVVYTPLGP
HHCCCCCHHHHHHCCCHHHHCCCCEEEEECHHHHHHHHCCCCCEEEEEECCCEEECCCCC
VPSQRKFTVAGVFEMGSQVDATLAYVHHDDAQRLMRQKAGEIKELRLYLDDPFNAAKIAP
CCCCCEEEEEEHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCHHHCCH
EVIDQFAVPVTTTDWRDTYGHLFGAVKMEKNMMSLMLSLIIAVAAFNIVSALVMMVVDKT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDVAVLKTQGLTTANVMGIFMIQGSLNAVIGLISGVAVGTLLTLNLNTITQALGISILGA
CCEEEEEECCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHCCEEEEC
GQNLPVQLELSQLTWIVVGTLVITLVATVYPAIRAANVQPATALRYE
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]