Click here to switch to the map view.

The map label for this gene is hscB

Identifier: 167623506

GI number: 167623506

Start: 1892782

End: 1893306

Strand: Direct

Name: hscB

Synonym: Shal_1575

Alternate gene names: 167623506

Gene position: 1892782-1893306 (Clockwise)

Preceding gene: 167623505

Following gene: 167623507

Centisome position: 36.21

GC content: 43.43

Gene sequence:

>525_bases
ATGAATTATTTCGAGCTGTTTAGTTTACTTCCTTCCTATGATGTCGACACCGCCTTACTTGCAGAGCGCTACCGCGAACT
GCAACGGGCGGTTCATCCCGACAAATTTGCTAACGCGAGTGAGCAAGATAAGCGTCTGTCTGTACAGCGTACTGCACAAA
TCAATGATGCTTTTCAAACACTGAAGAATCCTATTCAAAGAGCTGAGCACTTGCTTACATTGAAAGGACTTGAGCTGAGT
CATGAGTCGACAACATTAAAAGATACCCAGTTTTTAATGCAACAGATGGAATGGCGTGAGTCACTTGAAGAGATCAAGCA
TAGCGATGATCCCGACTCTGAGATAGCCGAACTCTACGATTCTTTTGAGCAATACGCTAGGCAAATAACGACAGAATTAA
AGCCTTTACTGGTGAGCGAGCTTGAGGCAGATCATTTGCAGGCCGCAGAGCAAATTCGTAAACTTAAGTTTATGGCAAAA
TTACAAGATGAGTTGACCAGAGTGGAAGATGCACTCTTTGATTAG

Upstream 100 bases:

>100_bases
AGAAGGTCTTAACGAAGGTTTCCAATTCAATAACCCTAATGCGAAAGGTGAATGTGGCTGCGGTGAGAGCTTTACCGTCT
AAGCCATTAAAAGTAAAACT

Downstream 100 bases:

>100_bases
TCAACGGTCTTAATTTTTAATACTGTTGGCTCAAGACATTGAGCCAACATTTTTTTAAGTTGGATATATATGGCACTTTT
GCAGATAGCAGAGCCTGGAC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNYFELFSLLPSYDVDTALLAERYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQTLKNPIQRAEHLLTLKGLELS
HESTTLKDTQFLMQQMEWRESLEEIKHSDDPDSEIAELYDSFEQYARQITTELKPLLVSELEADHLQAAEQIRKLKFMAK
LQDELTRVEDALFD

Sequences:

>Translated_174_residues
MNYFELFSLLPSYDVDTALLAERYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQTLKNPIQRAEHLLTLKGLELS
HESTTLKDTQFLMQQMEWRESLEEIKHSDDPDSEIAELYDSFEQYARQITTELKPLLVSELEADHLQAAEQIRKLKFMAK
LQDELTRVEDALFD
>Mature_174_residues
MNYFELFSLLPSYDVDTALLAERYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQTLKNPIQRAEHLLTLKGLELS
HESTTLKDTQFLMQQMEWRESLEEIKHSDDPDSEIAELYDSFEQYARQITTELKPLLVSELEADHLQAAEQIRKLKFMAK
LQDELTRVEDALFD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=165, Percent_Identity=32.7272727272727, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1788876, Length=175, Percent_Identity=41.1428571428571, Blast_Score=125, Evalue=1e-30,
Organism=Drosophila melanogaster, GI161084223, Length=174, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_SHEHH (B0TNY4)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673800.1
- ProteinModelPortal:   B0TNY4
- SMR:   B0TNY4
- GeneID:   5904793
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1575
- HOGENOM:   HBG751004
- OMA:   INDSESK
- ProtClustDB:   PRK05014
- BioCyc:   SHAL458817:SHAL_1575-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 20390; Mature: 20390

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFSLLPSYDVDTALLAERYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQT
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKNPIQRAEHLLTLKGLELSHESTTLKDTQFLMQQMEWRESLEEIKHSDDPDSEIAELYD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SFEQYARQITTELKPLLVSELEADHLQAAEQIRKLKFMAKLQDELTRVEDALFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFSLLPSYDVDTALLAERYRELQRAVHPDKFANASEQDKRLSVQRTAQINDAFQT
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKNPIQRAEHLLTLKGLELSHESTTLKDTQFLMQQMEWRESLEEIKHSDDPDSEIAELYD
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SFEQYARQITTELKPLLVSELEADHLQAAEQIRKLKFMAKLQDELTRVEDALFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA