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The map label for this gene is zntR [H]

Identifier: 167622429

GI number: 167622429

Start: 589431

End: 589946

Strand: Direct

Name: zntR [H]

Synonym: Shal_0489

Alternate gene names: 167622429

Gene position: 589431-589946 (Clockwise)

Preceding gene: 167622425

Following gene: 167622430

Centisome position: 11.28

GC content: 46.9

Gene sequence:

>516_bases
ATGTATCGAATAGGTGAGCTTGCACAACAGTGTGAAGTGAAGACCGATACCTTAAGGTTTTATGAAAAGCATGGCTTGTT
GTCGCCATCGTCTCGTACCGATTCCGGTTACCGGATCTATACCGAGGCCGATGCCCAGCGTTTACGCTTTATTTTGCGTG
CTAAAGCGGTGGGTTTTACCTTAGCGGAGATCACTGAGCTGCTGTCTATTGAGCTAGATAGGTCTAATTGGGCCTGCGCC
GATGTGAAGGGCTTAGTCGATGTTAAACTTGCTAATGTTGAAGCGAAAATTGCCGAGCTAAACCATTTTCAATTGTCACT
GCAGCGCCTATCTCAGGCCTGTTGTGGTGGTCCTGAAAGCGCAGAGCACTGTTCGATTCTTGAAGCATTGGAGTCGAATA
CCGACAGCATCCGCTGTGAAAATGACAAGCATCGTCACGGTGAGCAAGAGTTCACTAAGACCTGCAGTGATAAATCGATA
GCTAAATCGATAACGAAGAAAACACACGAGAAGTAG

Upstream 100 bases:

>100_bases
CCAAGGTTTATACTTTAGAAATTCAAGCGAGTAAATCAGACCAATTTGAAGATTTACTCTCTGATGTCGATATTAAATTC
AAGGTTGATTTGGAGCTGGC

Downstream 100 bases:

>100_bases
TTATGTTATTTGAAAACTTTATTGAGCTGTTTCTAGAGTCCGCGCCTTGGTTGTTACTGGGCTTAGTATTAGCAGGCATG
TTGAAAATGTTCGTGCCAAT

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MYRIGELAQQCEVKTDTLRFYEKHGLLSPSSRTDSGYRIYTEADAQRLRFILRAKAVGFTLAEITELLSIELDRSNWACA
DVKGLVDVKLANVEAKIAELNHFQLSLQRLSQACCGGPESAEHCSILEALESNTDSIRCENDKHRHGEQEFTKTCSDKSI
AKSITKKTHEK

Sequences:

>Translated_171_residues
MYRIGELAQQCEVKTDTLRFYEKHGLLSPSSRTDSGYRIYTEADAQRLRFILRAKAVGFTLAEITELLSIELDRSNWACA
DVKGLVDVKLANVEAKIAELNHFQLSLQRLSQACCGGPESAEHCSILEALESNTDSIRCENDKHRHGEQEFTKTCSDKSI
AKSITKKTHEK
>Mature_171_residues
MYRIGELAQQCEVKTDTLRFYEKHGLLSPSSRTDSGYRIYTEADAQRLRFILRAKAVGFTLAEITELLSIELDRSNWACA
DVKGLVDVKLANVEAKIAELNHFQLSLQRLSQACCGGPESAEHCSILEALESNTDSIRCENDKHRHGEQEFTKTCSDKSI
AKSITKKTHEK

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=138, Percent_Identity=51.4492753623188, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=34.6456692913386, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 19250; Mature: 19250

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELAQQCEVKTDTLRFYEKHGLLSPSSRTDSGYRIYTEADAQRLRFILRAKAVGFT
CCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
LAEITELLSIELDRSNWACADVKGLVDVKLANVEAKIAELNHFQLSLQRLSQACCGGPES
HHHHHHHHHEEECCCCCCHHHHCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALESNTDSIRCENDKHRHGEQEFTKTCSDKSIAKSITKKTHEK
HHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYRIGELAQQCEVKTDTLRFYEKHGLLSPSSRTDSGYRIYTEADAQRLRFILRAKAVGFT
CCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
LAEITELLSIELDRSNWACADVKGLVDVKLANVEAKIAELNHFQLSLQRLSQACCGGPES
HHHHHHHHHEEECCCCCCHHHHCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALESNTDSIRCENDKHRHGEQEFTKTCSDKSIAKSITKKTHEK
HHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]