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The map label for this gene is dtd

Identifier: 167622304

GI number: 167622304

Start: 429455

End: 429892

Strand: Direct

Name: dtd

Synonym: Shal_0363

Alternate gene names: 167622304

Gene position: 429455-429892 (Clockwise)

Preceding gene: 167622303

Following gene: 167622333

Centisome position: 8.22

GC content: 48.17

Gene sequence:

>438_bases
GTGATTGCCCTAATTCAACGTGTGAGTGAAGCAAAAGTTGTCGTTGATGGCGCGACTATCGGTGAGATAGATAGAGGCCT
ATTGGTGTTACTCGGTGTTGAGCGCGAGGATAACATTGAGAAGATGCAAAAGTTGGCTACCAAGGTGATGAGCTACCGGG
TGTTCTCCGATGAGAATGGCAAGATGAACCTTAATCTTGAACAAGCGGGTGGCAGTCTGTTAGTGGTATCACAATTTACT
TTAGCCGCAGATACGGGGCGAGGGTTGCGTCCGAGTTTTTCAGGTGCGGGTACGCCGGAACAAGCGCGCGAACTCTATGA
AGCTTTTATCGATTTTTGCAAATCCAAAGGGGTTAACACCCAAACCGGTCAATTTGCCGCAGACATGAAAGTCTCTTTGG
TTAACGACGGTCCAGTGACCTTTAACCTGCAAGTCTAG

Upstream 100 bases:

>100_bases
GGAGCGAAGCGTCCTAGAACCTAGTGCCTTGTTTTAAAGCGAAGCGTTCGTCTTCGCTTTTTCATTTAAGTTATTAATTT
TTTATCGGAGAGTGTTGTAC

Downstream 100 bases:

>100_bases
GGCTTTTATGGTGAGCAGCGGATTATTTTGGATAAGCCTGTGACAGACTCAAACCATCAATCCTTGCTAAAGCAACTGCA
GCAGACTTGGCATCAAACCA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRVSEAKVVVDGATIGEIDRGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPEQARELYEAFIDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV

Sequences:

>Translated_145_residues
MIALIQRVSEAKVVVDGATIGEIDRGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPEQARELYEAFIDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV
>Mature_145_residues
MIALIQRVSEAKVVVDGATIGEIDRGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPEQARELYEAFIDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=37.4149659863946, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=64.1379310344827, Blast_Score=196, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=39.8648648648649, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=40.4109589041096, Blast_Score=109, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=37.6712328767123, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_SHEHH (B0TPR8)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001672598.1
- ProteinModelPortal:   B0TPR8
- SMR:   B0TPR8
- GeneID:   5905838
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_0363
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   SHAL458817:SHAL_0363-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15687; Mature: 15687

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSEAKVVVDGATIGEIDRGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENG
CHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNLEQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPEQARELYEAFIDFCKSKGVNT
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QTGQFAADMKVSLVNDGPVTFNLQV
CCCCEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSEAKVVVDGATIGEIDRGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENG
CHHHHHHCCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNLEQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPEQARELYEAFIDFCKSKGVNT
EEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QTGQFAADMKVSLVNDGPVTFNLQV
CCCCEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA