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The map label for this gene is menC [H]

Identifier: 167622236

GI number: 167622236

Start: 354351

End: 355412

Strand: Reverse

Name: menC [H]

Synonym: Shal_0295

Alternate gene names: 167622236

Gene position: 355412-354351 (Counterclockwise)

Preceding gene: 167622237

Following gene: 167622235

Centisome position: 6.8

GC content: 49.72

Gene sequence:

>1062_bases
ATGACCGCGACTCTACAGCAAGCAAAGCCATTAACCTTAGCTAGGTTAGGTCTGTATCAGTTTGCTATCGATTTAGATAA
GCCGCTGCCTGTAGGCAAGCAACGCATAGAACAGCGCCGTGGACTCGTGCTGGTAGCACAGACCCAAGAGCGACAAGAAT
GGGTAGAGATCTCGCCGCTTTGTGGTGTCGATAACCAAGGTGAAACGATTTCAGGCTTTAGCCAAGAGACGCTCGAGGGG
GTGAGCCAGCAGCTACTGAATTTACTGCCAGAACTACAGCAGCAGCCTATCGATTGTTTATTAACGCTTGCCGAGCAGAG
CAAGCTGCCGTCATTAGCCTATGGTTTGAGCCTAATGCATGCCAAGCTAATGGGTAAGCTCGACGGACACACATTAACTG
CGCGCACAGTGCCACTTATCTATCGCCAAGCTGATGAGTCTCTTAGCCTTGTGGCTAACAGAGTTAGCGCGCTGCCTGAG
ACCATACTTTCAGTCAAAGTGAAAGTGGCTCAAGACTCATTAAAGGATGAGCTGCAGCTAATCCATCATATCTTAGCGAT
TCGCCCTAAGCTCAAGCTGCGCCTAGACGCTAACCGTGGCTTTAGCCTAGAGCAGGCTATCGAGTTTGCCGCCTGTGTGC
CACTCGACAGCATCGAGTACATCGAAGAACCTTGTCAAAATCCTCAAGACAACCGTGCTTTCTATCAAGCCATTAAGATG
CCTTGGGCGCTGGATGAGTCACTCAACAGTCCAGATTATCAATTTTCAATGCAGTCAGGGCTAAGCGCACTCATCATCAA
GCCAACCCTGTTAGGCAGCCTCGAAAAACTACAGCAGCTGATTGATACCGCAGCAGAGCATGGCGTACGCACTGTTTTGA
GTTCAAGTTTAGAGGCAAGCTTAGGTATTGAGGCCATAAGCCGACTGGCACAGATCTTCACACCCGACGAAACTCCCGGT
ATAGATACACTCGGCGCCTTTAGCCAAGATCTGCTGGTGAGTTCAGGTAAAGAGTACTGCCTAAAGCTTGAAGAGTTAAC
GCCGCTACTCGAACTAAGCTAG

Upstream 100 bases:

>100_bases
TGGCCATAACGTACATCTGGCAGCTCCCGAGGCTTTTGCAGAGCAACTCAAAACCATTTTTGCATCGAACTCTAACTTCT
AACTAGACAGTGAGCACTCC

Downstream 100 bases:

>100_bases
ATTAGGCTAGGTTTGGTTAGATTAGGCTAGGTTTGGTTAGATTAGACTAGATGTGGCTAACATAAGACTAGAGTCGTAAT
AGCCTAGGTGGCGATACCCT

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTATLQQAKPLTLARLGLYQFAIDLDKPLPVGKQRIEQRRGLVLVAQTQERQEWVEISPLCGVDNQGETISGFSQETLEG
VSQQLLNLLPELQQQPIDCLLTLAEQSKLPSLAYGLSLMHAKLMGKLDGHTLTARTVPLIYRQADESLSLVANRVSALPE
TILSVKVKVAQDSLKDELQLIHHILAIRPKLKLRLDANRGFSLEQAIEFAACVPLDSIEYIEEPCQNPQDNRAFYQAIKM
PWALDESLNSPDYQFSMQSGLSALIIKPTLLGSLEKLQQLIDTAAEHGVRTVLSSSLEASLGIEAISRLAQIFTPDETPG
IDTLGAFSQDLLVSSGKEYCLKLEELTPLLELS

Sequences:

>Translated_353_residues
MTATLQQAKPLTLARLGLYQFAIDLDKPLPVGKQRIEQRRGLVLVAQTQERQEWVEISPLCGVDNQGETISGFSQETLEG
VSQQLLNLLPELQQQPIDCLLTLAEQSKLPSLAYGLSLMHAKLMGKLDGHTLTARTVPLIYRQADESLSLVANRVSALPE
TILSVKVKVAQDSLKDELQLIHHILAIRPKLKLRLDANRGFSLEQAIEFAACVPLDSIEYIEEPCQNPQDNRAFYQAIKM
PWALDESLNSPDYQFSMQSGLSALIIKPTLLGSLEKLQQLIDTAAEHGVRTVLSSSLEASLGIEAISRLAQIFTPDETPG
IDTLGAFSQDLLVSSGKEYCLKLEELTPLLELS
>Mature_352_residues
TATLQQAKPLTLARLGLYQFAIDLDKPLPVGKQRIEQRRGLVLVAQTQERQEWVEISPLCGVDNQGETISGFSQETLEGV
SQQLLNLLPELQQQPIDCLLTLAEQSKLPSLAYGLSLMHAKLMGKLDGHTLTARTVPLIYRQADESLSLVANRVSALPET
ILSVKVKVAQDSLKDELQLIHHILAIRPKLKLRLDANRGFSLEQAIEFAACVPLDSIEYIEEPCQNPQDNRAFYQAIKMP
WALDESLNSPDYQFSMQSGLSALIIKPTLLGSLEKLQQLIDTAAEHGVRTVLSSSLEASLGIEAISRLAQIFTPDETPGI
DTLGAFSQDLLVSSGKEYCLKLEELTPLLELS

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=311, Percent_Identity=35.048231511254, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 38948; Mature: 38817

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATLQQAKPLTLARLGLYQFAIDLDKPLPVGKQRIEQRRGLVLVAQTQERQEWVEISPL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCCHHHHHEECCC
CGVDNQGETISGFSQETLEGVSQQLLNLLPELQQQPIDCLLTLAEQSKLPSLAYGLSLMH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHH
AKLMGKLDGHTLTARTVPLIYRQADESLSLVANRVSALPETILSVKVKVAQDSLKDELQL
HHHHHHCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHHILAIRPKLKLRLDANRGFSLEQAIEFAACVPLDSIEYIEEPCQNPQDNRAFYQAIKM
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHC
PWALDESLNSPDYQFSMQSGLSALIIKPTLLGSLEKLQQLIDTAAEHGVRTVLSSSLEAS
CHHHHHCCCCCCCEEEHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIEAISRLAQIFTPDETPGIDTLGAFSQDLLVSSGKEYCLKLEELTPLLELS
HCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
TATLQQAKPLTLARLGLYQFAIDLDKPLPVGKQRIEQRRGLVLVAQTQERQEWVEISPL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCCHHHHHEECCC
CGVDNQGETISGFSQETLEGVSQQLLNLLPELQQQPIDCLLTLAEQSKLPSLAYGLSLMH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHH
AKLMGKLDGHTLTARTVPLIYRQADESLSLVANRVSALPETILSVKVKVAQDSLKDELQL
HHHHHHCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHHILAIRPKLKLRLDANRGFSLEQAIEFAACVPLDSIEYIEEPCQNPQDNRAFYQAIKM
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHC
PWALDESLNSPDYQFSMQSGLSALIIKPTLLGSLEKLQQLIDTAAEHGVRTVLSSSLEAS
CHHHHHCCCCCCCEEEHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIEAISRLAQIFTPDETPGIDTLGAFSQDLLVSSGKEYCLKLEELTPLLELS
HCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA