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The map label for this gene is 167622166

Identifier: 167622166

GI number: 167622166

Start: 272273

End: 273124

Strand: Direct

Name: 167622166

Synonym: Shal_0225

Alternate gene names: NA

Gene position: 272273-273124 (Clockwise)

Preceding gene: 167622165

Following gene: 167622167

Centisome position: 5.21

GC content: 48.12

Gene sequence:

>852_bases
ATGGCGTTGAAATTAGAGATGCAAGGGCAAACCTACGGCCCATTCGTTAATGAGTATACCGCTAGAGATGTGATGCTGTT
CGCGCTGGGTTGTGGTGCTGGCAGTGACGGTAAAACTGATCTCGATTATGTGTATGAGAAGCAATTAAAGGTACTGCCTA
TCTTTGCTGCGACGCAAATTGTCGATGCAGAGGTGACTAAGACTATCGATTATGGCTTTAATTGGGGCGGATCTTTGCAT
TGGGGTTTTGACCTGCATATTCATCAGCCACTGCCTACTAATCCTGGCAAATTGAGCACCAAGGTGTTGTTGAAGGGGCT
GTTCGACCGAGGGGAAGGACGCGGTTGTTTGGCGCAACACATAGGTGAAACCTTCGATGAGACGGGGACTAAACTGTTTA
CTAACGAGAGTTGGGATTGCGCGTTATACGATGGCGGCTTTGGCGGCCCAAAAGCGCCAGCAGATATTGTTGAGATCCCA
GAGCGCGCGCCAGATTTCGAAATTGAACAAGATATTCCACTAAACCAAGCGCTTATCTACCGACTATCGGGCGATGACCA
TCCTCAGCATGTGGATTGGGAATATGCGCAAGAGTTTGGTCACCCAAAACCGAATCTGCACGGTGTTAGCACTGCAGGTG
TGGCCTGTCGTCACATCATTCAGGCGATGTTTCCCGGTGAACCGGAGCGATTAACACGCTTTAAGACTCGGCTAACTAAA
TCCTTGTATCCCGGCGCAAGGGTCAAAACCCAAATTTGGAAGTGGGATGATAACTGTGTCCATTTCAGAGTGATGGATGC
CAACGATCCTGACACTTTTTATCTTAACTTTGGTTTAGTTGAGTGGAAGTAA

Upstream 100 bases:

>100_bases
TAGATAGGTTTCAGTGCTATCAATCGAAATAGAGCCTGATATTTCCCATGAGATATCGGGTTTTATTTTAACTGTTTGTC
GGTAATGGAAGGATTCACCA

Downstream 100 bases:

>100_bases
GCCTTTGTAGGAGGCTTTAGCCTCCTATCTAGACGAGAAATAGCATTTATCAACGTTAGTATTTAGCTGTGACGTCTTAA
TGTTTGAGGCGCAACAGCTA

Product: 3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoAhydratase

Products: NA

Alternate protein names: MaoC-Like Dehydratase; Dehydratase; Dehydrogenase; Acyl Dehydratase; UfaA2 Protein; MaoC-Like Domain-Containing; Enoyl-CoA Hydratase; Short-Chain Dehydrogenase/Reductase SDR; MaoC Family Protein; Hydratase; -Specific Enoyl-CoA Hydratase; 2-Enoyl Acyl-CoA Hydratase; MaoC Acyl Dehydratase; MaoC Family Dehydratase; Multifunctional; Enoyl-CoA Hydratase/3-Hydroxyacyl-CoA Dehydratase; MaoC Like Dehydratase/Enoyl-CoA Hydratase; MaoC-Like-Specific Enoyl-CoA Hydratase; MaoC-Like Domain-Containing Protein; MaoC Family Dehydrogenase/Dehydratase; MaoC Like Domain Protein

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MALKLEMQGQTYGPFVNEYTARDVMLFALGCGAGSDGKTDLDYVYEKQLKVLPIFAATQIVDAEVTKTIDYGFNWGGSLH
WGFDLHIHQPLPTNPGKLSTKVLLKGLFDRGEGRGCLAQHIGETFDETGTKLFTNESWDCALYDGGFGGPKAPADIVEIP
ERAPDFEIEQDIPLNQALIYRLSGDDHPQHVDWEYAQEFGHPKPNLHGVSTAGVACRHIIQAMFPGEPERLTRFKTRLTK
SLYPGARVKTQIWKWDDNCVHFRVMDANDPDTFYLNFGLVEWK

Sequences:

>Translated_283_residues
MALKLEMQGQTYGPFVNEYTARDVMLFALGCGAGSDGKTDLDYVYEKQLKVLPIFAATQIVDAEVTKTIDYGFNWGGSLH
WGFDLHIHQPLPTNPGKLSTKVLLKGLFDRGEGRGCLAQHIGETFDETGTKLFTNESWDCALYDGGFGGPKAPADIVEIP
ERAPDFEIEQDIPLNQALIYRLSGDDHPQHVDWEYAQEFGHPKPNLHGVSTAGVACRHIIQAMFPGEPERLTRFKTRLTK
SLYPGARVKTQIWKWDDNCVHFRVMDANDPDTFYLNFGLVEWK
>Mature_282_residues
ALKLEMQGQTYGPFVNEYTARDVMLFALGCGAGSDGKTDLDYVYEKQLKVLPIFAATQIVDAEVTKTIDYGFNWGGSLHW
GFDLHIHQPLPTNPGKLSTKVLLKGLFDRGEGRGCLAQHIGETFDETGTKLFTNESWDCALYDGGFGGPKAPADIVEIPE
RAPDFEIEQDIPLNQALIYRLSGDDHPQHVDWEYAQEFGHPKPNLHGVSTAGVACRHIIQAMFPGEPERLTRFKTRLTKS
LYPGARVKTQIWKWDDNCVHFRVMDANDPDTFYLNFGLVEWK

Specific function: Unknown

COG id: COG2030

COG function: function code I; Acyl dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4504505, Length=278, Percent_Identity=30.2158273381295, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17532783, Length=246, Percent_Identity=34.5528455284553, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322861, Length=268, Percent_Identity=30.9701492537313, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI18859837, Length=261, Percent_Identity=29.1187739463602, Blast_Score=107, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31840; Mature: 31709

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKLEMQGQTYGPFVNEYTARDVMLFALGCGAGSDGKTDLDYVYEKQLKVLPIFAATQI
CEEEEEECCCCCCCCHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEHHHHH
VDAEVTKTIDYGFNWGGSLHWGFDLHIHQPLPTNPGKLSTKVLLKGLFDRGEGRGCLAQH
HHHHHHHEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
IGETFDETGTKLFTNESWDCALYDGGFGGPKAPADIVEIPERAPDFEIEQDIPLNQALIY
HHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEE
RLSGDDHPQHVDWEYAQEFGHPKPNLHGVSTAGVACRHIIQAMFPGEPERLTRFKTRLTK
EECCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SLYPGARVKTQIWKWDDNCVHFRVMDANDPDTFYLNFGLVEWK
HHCCCCCEEEEEEEECCCEEEEEEEECCCCCEEEEEEEEEEEC
>Mature Secondary Structure 
ALKLEMQGQTYGPFVNEYTARDVMLFALGCGAGSDGKTDLDYVYEKQLKVLPIFAATQI
EEEEEECCCCCCCCHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEHHHHH
VDAEVTKTIDYGFNWGGSLHWGFDLHIHQPLPTNPGKLSTKVLLKGLFDRGEGRGCLAQH
HHHHHHHEEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
IGETFDETGTKLFTNESWDCALYDGGFGGPKAPADIVEIPERAPDFEIEQDIPLNQALIY
HHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEE
RLSGDDHPQHVDWEYAQEFGHPKPNLHGVSTAGVACRHIIQAMFPGEPERLTRFKTRLTK
EECCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SLYPGARVKTQIWKWDDNCVHFRVMDANDPDTFYLNFGLVEWK
HHCCCCCEEEEEEEECCCEEEEEEEECCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA