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The map label for this gene is mtnC [H]

Identifier: 167622008

GI number: 167622008

Start: 75502

End: 76179

Strand: Reverse

Name: mtnC [H]

Synonym: Shal_0067

Alternate gene names: 167622008

Gene position: 76179-75502 (Counterclockwise)

Preceding gene: 167622009

Following gene: 167622007

Centisome position: 1.46

GC content: 43.66

Gene sequence:

>678_bases
ATGGGTATCAGAGCCATCGTCGTTGATACAGCCGGTACGACTACCGACCTTAACTTTATTGAAGAGATTCTCTTTCCTTA
TTCAGCTAAGGCCTTACCCGCTTTTCTTGAAGAAAATCAACATAATGTACTCGTAGAGAACTGTATTTGCGATGTGCAAG
ATATTGCACTTGAACCAGATGCCAGTCTTGCTCGTGTAACTGAAATTTTACTGCAGTGGATTAAAGAAGACCGTAAAGCT
ACACCACTGAAAACCATTCAAGGTTTGATCTGGAAACAGGGCTACGCCAATGGTGAATTTAAGGGCCATATCTTCCCTGA
TTTTATCGAAGCATTAGATGGCTACAAGCAGCAAGGTCTACGTGTTTATAGCTTCTCTTCAGGCTCTGTTGAGGCGCAAA
AGTTATTGTTTAGCCACAGTGATGCAGGTGATCTCAACGATAAGTTTAATGGCCACTTTGACACTCGCACAGGCAACAAG
CGCTTTAAGCAGGCATATTGCAATATCGTCAACACTATCAGCCTAAGCCCGAAGCAGATTTTGTTTGTTTCTGACGTACT
TGAAGAGCTTAAAGCCGCTAGTGAAGCAGGCTTAAATGTGGTGCAGATGGTACGCGACGATAGCCAACGCACGGGCGACT
TTAAAACGATTAGCAGCTTTGCAGAGCTAAGCATTTAG

Upstream 100 bases:

>100_bases
GGCGCGATTACACTAGCCAAATCGAACGATTCAGCTTAGGATCTGAGCAATAAACCGATCTCGACTACACGTTATATACA
TTGCGGAGTGACCAAACATT

Downstream 100 bases:

>100_bases
CTCTATTGATTAATTAGAACGAAAGGCATTCTTTATGAATGCCTTTTTTGTCTCTATAACTTCCATTCTGTAATAGACAT
ATAAAGCTTTTCACGACATT

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGIRAIVVDTAGTTTDLNFIEEILFPYSAKALPAFLEENQHNVLVENCICDVQDIALEPDASLARVTEILLQWIKEDRKA
TPLKTIQGLIWKQGYANGEFKGHIFPDFIEALDGYKQQGLRVYSFSSGSVEAQKLLFSHSDAGDLNDKFNGHFDTRTGNK
RFKQAYCNIVNTISLSPKQILFVSDVLEELKAASEAGLNVVQMVRDDSQRTGDFKTISSFAELSI

Sequences:

>Translated_225_residues
MGIRAIVVDTAGTTTDLNFIEEILFPYSAKALPAFLEENQHNVLVENCICDVQDIALEPDASLARVTEILLQWIKEDRKA
TPLKTIQGLIWKQGYANGEFKGHIFPDFIEALDGYKQQGLRVYSFSSGSVEAQKLLFSHSDAGDLNDKFNGHFDTRTGNK
RFKQAYCNIVNTISLSPKQILFVSDVLEELKAASEAGLNVVQMVRDDSQRTGDFKTISSFAELSI
>Mature_224_residues
GIRAIVVDTAGTTTDLNFIEEILFPYSAKALPAFLEENQHNVLVENCICDVQDIALEPDASLARVTEILLQWIKEDRKAT
PLKTIQGLIWKQGYANGEFKGHIFPDFIEALDGYKQQGLRVYSFSSGSVEAQKLLFSHSDAGDLNDKFNGHFDTRTGNKR
FKQAYCNIVNTISLSPKQILFVSDVLEELKAASEAGLNVVQMVRDDSQRTGDFKTISSFAELSI

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=252, Percent_Identity=36.5079365079365, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI115533232, Length=215, Percent_Identity=37.6744186046512, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6320797, Length=201, Percent_Identity=32.3383084577114, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI281360080, Length=237, Percent_Identity=37.1308016877637, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24644163, Length=237, Percent_Identity=37.1308016877637, Blast_Score=166, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR005833 [H]

Pfam domain/function: NA

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 25071; Mature: 24939

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRAIVVDTAGTTTDLNFIEEILFPYSAKALPAFLEENQHNVLVENCICDVQDIALEPD
CCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEHHHHHCCHHHHCCCCC
ASLARVTEILLQWIKEDRKATPLKTIQGLIWKQGYANGEFKGHIFPDFIEALDGYKQQGL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RVYSFSSGSVEAQKLLFSHSDAGDLNDKFNGHFDTRTGNKRFKQAYCNIVNTISLSPKQI
EEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHH
LFVSDVLEELKAASEAGLNVVQMVRDDSQRTGDFKTISSFAELSI
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GIRAIVVDTAGTTTDLNFIEEILFPYSAKALPAFLEENQHNVLVENCICDVQDIALEPD
CCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEHHHHHCCHHHHCCCCC
ASLARVTEILLQWIKEDRKATPLKTIQGLIWKQGYANGEFKGHIFPDFIEALDGYKQQGL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCC
RVYSFSSGSVEAQKLLFSHSDAGDLNDKFNGHFDTRTGNKRFKQAYCNIVNTISLSPKQI
EEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHH
LFVSDVLEELKAASEAGLNVVQMVRDDSQRTGDFKTISSFAELSI
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA