| Definition | Thermoanaerobacter sp. X514 chromosome, complete genome. |
|---|---|
| Accession | NC_010320 |
| Length | 2,457,259 |
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The map label for this gene is comEC [H]
Identifier: 167040715
GI number: 167040715
Start: 2102940
End: 2105213
Strand: Reverse
Name: comEC [H]
Synonym: Teth514_2092
Alternate gene names: 167040715
Gene position: 2105213-2102940 (Counterclockwise)
Preceding gene: 167040716
Following gene: 167040714
Centisome position: 85.67
GC content: 32.45
Gene sequence:
>2274_bases ATGGAATTTCCATTTTTATATCTTACTGTAGCTCTTTCTTTAGGAATAATAATTGGAAGATATGTTTTTTATCCTTTTGC TTTTTTGCTTTTATTAGCAATTTCAGTGGCTATTTCTTTGTGGGGGTATTTGAAAAATAAAAATGTCAGTTTACTTCTTT TAATTTCTTTTATTTTTGTAGGTGCAATTTTAAGTGGCAATGCTCTTAATTCTCCCAATCCTTATCTAAAATTTGAAGAT AAATTTATAACTATAAAGGGCAAGGTGCAGGAGGTAAGAGAATATGAGGGATATGCTAAATACATAGTTAAACCGACTAA TTTACCTAAAGTATTGTTTACTCAATATGGGGGCAAATATCCTTCTGATGGAGATGTTGTAAGTATAAGGGGGATAGTTT CAATACCTAAAAGGGCTACAAATCCAGGAGGTTTTGACTACAAACTCTTTTTAAAGAAAAAAGGAATTTATGCAGTCATG AGAGTGCAGGGGTATGCCGTTGACATTGTGGGCAAAGGCAATTTAAATTTTATTGAGAAGGTTATATATGCTGCAAAGCA AAAAACAGAAGTTAATTATATAAATTCAATGCCCGAAAGAGATGCTAAGTTTGTTATATCGATTTTTTTAGGAGATAAAC TTGTTGACGATGAGACTTTGGTACAATTTAGGACAGCAGGTATTTCACATATTATTTCCGTATCAGGAATGCACGTAGCA ATCATAACAGGTTTTATACTTTATATGTTAAGTCTTTTTAACATTAGAAGGTACAAAGTTCCTATCATTATAATTGTATT GACCTTCTATGCAATTTTAACAGGAGCAAATCCGCCAGTTATAAGGGCAGCTCTTATGGCTTCTATCGCTTTAATTGGCA CTACTTATGGCAAAAAACATAATTCTATAAATTCTTTGTCTTTTGCTGCTTTTGTGATATTAATATTTAATCCTTTAATG CTGTGGGATGTAGGTTTTCAACTTTCATTTGTTGCTACTTTAGCTATTTTGTATTTCTATAAGCCGATACGAGAAAAATT ATCAATGCTAAATCCCAAAATACGAGAATTAGTCGCTTTAACTCTTTCTGCTCAAATTGGCACAATCCCCTTTACCATGT ATTATTTTCATTATATATCCATAATTTCGCTTTTGTCCAACATTGTAATAGTGCCATTGGCGAATATAGCAGTCGTTTTG GGATTTTTATCGGCTATGATAGGGCTGATTTTTCCTCCCTTGTCCTATTTTATAAATTTTATAAATATACCTGTTGTAGA AGTTATTTTGTACATAACGAAATTATTCAATAGCTTTCCTTATGCCAGTATAAATACTATTGTTCCGCCTTTGTATGTGA TTGTTTTGTATTATGGGATTTTAGCAGTCCTACTTAGCAGTTTTGATAAAAAAACTAAAAAGATTTCTATTGCAATTGCC TTGACTTTTGTTATAGCAATTTTCTTTTATAATTATCTATTGCCTAAAGATTTAGAAGTGACTTTCCTGGATGTAGGACA AGGGGACAGCACTTTTGTCAGGACACCCCACGGCAAAACTTTTTTAATAGATGGGGGAGGCAGGCCCTTATTTGCAATTT CTTCATTTGATGTCGGAGAAGATGTGGTACTTCCATTTTTGTATTACAAAGGTGTTATGAAGCTTGATGGAGTTTTTATA TCCCATACTGACATCGACCATGTAGGCGGGATACTTAGTATTTTGCAGCAAATGAAAGTTGACAAAATCTTTATAGGGAT ACAAAAAGTTACTGATGATAATTTCAAAGAATTGATGGAAATTGCAAAATCAAAAAACATTCCCGTTGTGTTTTTAAAAA AGGGTGATAAAGTCAAAGTAGATGGTGTTGAAATATATGTTTTGCACCCTGACCCAGCAAATTTGATAGAAGAAAATCCT ATAAATAACAATGGTCTTGTTTTTAAAATGAAGTATAAAGATATGGAGTTTTTATTTACAGGTGATATAGAAAAACCGGC CGAAGAAATTTTAAAGAATTTAGACATAAAGACTGATATTTTGAAGGTGGCTCACCATGGGTCAAGTACTTCATCTTCAG AAGAATTCATTGAAAAAGCCAATCCGAAAATATGTATTCTCCAAGTAGGTAAAAACAGTTATGGACTCCCTGATGAGAGA GTGCTAAAATATCTTCAAGAAAGGTCTATAGTGTATAGAACAGACAAAAATGGTACCATTATTGTAAAGACAGATGGGAA AAAGGCATATATAAGGACTGTTCTTAAGGAGTGA
Upstream 100 bases:
>100_bases TTGTCACCGTTTATTTCTATCAAGGATTATTATGATGAAGCAATTAAAGTATTTGGAAATATAGAAATTGCGAGAGATTT TGAAGTTTATGTGATATAAA
Downstream 100 bases:
>100_bases AAGAATGAAGTATAAAGAATTAATAGACAGTTTAAAAAAAGGAGAAATACATAATATATATCTTTTTTACGGAGAAGAGA GATTTTTGTTGTCAGACGCT
Product: DNA internalization-related competence protein ComEC/Rec2
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 757; Mature: 757
Protein sequence:
>757_residues MEFPFLYLTVALSLGIIIGRYVFYPFAFLLLLAISVAISLWGYLKNKNVSLLLLISFIFVGAILSGNALNSPNPYLKFED KFITIKGKVQEVREYEGYAKYIVKPTNLPKVLFTQYGGKYPSDGDVVSIRGIVSIPKRATNPGGFDYKLFLKKKGIYAVM RVQGYAVDIVGKGNLNFIEKVIYAAKQKTEVNYINSMPERDAKFVISIFLGDKLVDDETLVQFRTAGISHIISVSGMHVA IITGFILYMLSLFNIRRYKVPIIIIVLTFYAILTGANPPVIRAALMASIALIGTTYGKKHNSINSLSFAAFVILIFNPLM LWDVGFQLSFVATLAILYFYKPIREKLSMLNPKIRELVALTLSAQIGTIPFTMYYFHYISIISLLSNIVIVPLANIAVVL GFLSAMIGLIFPPLSYFINFINIPVVEVILYITKLFNSFPYASINTIVPPLYVIVLYYGILAVLLSSFDKKTKKISIAIA LTFVIAIFFYNYLLPKDLEVTFLDVGQGDSTFVRTPHGKTFLIDGGGRPLFAISSFDVGEDVVLPFLYYKGVMKLDGVFI SHTDIDHVGGILSILQQMKVDKIFIGIQKVTDDNFKELMEIAKSKNIPVVFLKKGDKVKVDGVEIYVLHPDPANLIEENP INNNGLVFKMKYKDMEFLFTGDIEKPAEEILKNLDIKTDILKVAHHGSSTSSSEEFIEKANPKICILQVGKNSYGLPDER VLKYLQERSIVYRTDKNGTIIVKTDGKKAYIRTVLKE
Sequences:
>Translated_757_residues MEFPFLYLTVALSLGIIIGRYVFYPFAFLLLLAISVAISLWGYLKNKNVSLLLLISFIFVGAILSGNALNSPNPYLKFED KFITIKGKVQEVREYEGYAKYIVKPTNLPKVLFTQYGGKYPSDGDVVSIRGIVSIPKRATNPGGFDYKLFLKKKGIYAVM RVQGYAVDIVGKGNLNFIEKVIYAAKQKTEVNYINSMPERDAKFVISIFLGDKLVDDETLVQFRTAGISHIISVSGMHVA IITGFILYMLSLFNIRRYKVPIIIIVLTFYAILTGANPPVIRAALMASIALIGTTYGKKHNSINSLSFAAFVILIFNPLM LWDVGFQLSFVATLAILYFYKPIREKLSMLNPKIRELVALTLSAQIGTIPFTMYYFHYISIISLLSNIVIVPLANIAVVL GFLSAMIGLIFPPLSYFINFINIPVVEVILYITKLFNSFPYASINTIVPPLYVIVLYYGILAVLLSSFDKKTKKISIAIA LTFVIAIFFYNYLLPKDLEVTFLDVGQGDSTFVRTPHGKTFLIDGGGRPLFAISSFDVGEDVVLPFLYYKGVMKLDGVFI SHTDIDHVGGILSILQQMKVDKIFIGIQKVTDDNFKELMEIAKSKNIPVVFLKKGDKVKVDGVEIYVLHPDPANLIEENP INNNGLVFKMKYKDMEFLFTGDIEKPAEEILKNLDIKTDILKVAHHGSSTSSSEEFIEKANPKICILQVGKNSYGLPDER VLKYLQERSIVYRTDKNGTIIVKTDGKKAYIRTVLKE >Mature_757_residues MEFPFLYLTVALSLGIIIGRYVFYPFAFLLLLAISVAISLWGYLKNKNVSLLLLISFIFVGAILSGNALNSPNPYLKFED KFITIKGKVQEVREYEGYAKYIVKPTNLPKVLFTQYGGKYPSDGDVVSIRGIVSIPKRATNPGGFDYKLFLKKKGIYAVM RVQGYAVDIVGKGNLNFIEKVIYAAKQKTEVNYINSMPERDAKFVISIFLGDKLVDDETLVQFRTAGISHIISVSGMHVA IITGFILYMLSLFNIRRYKVPIIIIVLTFYAILTGANPPVIRAALMASIALIGTTYGKKHNSINSLSFAAFVILIFNPLM LWDVGFQLSFVATLAILYFYKPIREKLSMLNPKIRELVALTLSAQIGTIPFTMYYFHYISIISLLSNIVIVPLANIAVVL GFLSAMIGLIFPPLSYFINFINIPVVEVILYITKLFNSFPYASINTIVPPLYVIVLYYGILAVLLSSFDKKTKKISIAIA LTFVIAIFFYNYLLPKDLEVTFLDVGQGDSTFVRTPHGKTFLIDGGGRPLFAISSFDVGEDVVLPFLYYKGVMKLDGVFI SHTDIDHVGGILSILQQMKVDKIFIGIQKVTDDNFKELMEIAKSKNIPVVFLKKGDKVKVDGVEIYVLHPDPANLIEENP INNNGLVFKMKYKDMEFLFTGDIEKPAEEILKNLDIKTDILKVAHHGSSTSSSEEFIEKANPKICILQVGKNSYGLPDER VLKYLQERSIVYRTDKNGTIIVKTDGKKAYIRTVLKE
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG2333
COG function: function code R; Predicted hydrolase (metallo-beta-lactamase superfamily)
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
Organism=Escherichia coli, GI87081801, Length=763, Percent_Identity=22.1494102228047, Blast_Score=151, Evalue=1e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 84853; Mature: 84853
Theoretical pI: Translated: 9.71; Mature: 9.71
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEFPFLYLTVALSLGIIIGRYVFYPFAFLLLLAISVAISLWGYLKNKNVSLLLLISFIFV CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH GAILSGNALNSPNPYLKFEDKFITIKGKVQEVREYEGYAKYIVKPTNLPKVLFTQYGGKY HHHHCCCCCCCCCCCEEECCEEEEEECHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCC PSDGDVVSIRGIVSIPKRATNPGGFDYKLFLKKKGIYAVMRVQGYAVDIVGKGNLNFIEK CCCCCEEEEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCEEEEEEECCCHHHHHH VIYAAKQKTEVNYINSMPERDAKFVISIFLGDKLVDDETLVQFRTAGISHIISVSGMHVA HHHHHHCCCCHHHHHCCCCCCHHEEEEEEECCEECCCHHHHHHHHHHHHHHHHHCCCHHH IITGFILYMLSLFNIRRYKVPIIIIVLTFYAILTGANPPVIRAALMASIALIGTTYGKKH HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC NSINSLSFAAFVILIFNPLMLWDVGFQLSFVATLAILYFYKPIREKLSMLNPKIRELVAL CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH TLSAQIGTIPFTMYYFHYISIISLLSNIVIVPLANIAVVLGFLSAMIGLIFPPLSYFINF HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH INIPVVEVILYITKLFNSFPYASINTIVPPLYVIVLYYGILAVLLSSFDKKTKKISIAIA HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHH LTFVIAIFFYNYLLPKDLEVTFLDVGQGDSTFVRTPHGKTFLIDGGGRPLFAISSFDVGE HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCEEEEECCCCEEEEEECCCCCC DVVLPFLYYKGVMKLDGVFISHTDIDHVGGILSILQQMKVDKIFIGIQKVTDDNFKELME HHHHHHHHHCCHHHHCCEEEECCCHHHHHHHHHHHHHHCHHHHEEEEECCCCCCHHHHHH IAKSKNIPVVFLKKGDKVKVDGVEIYVLHPDPANLIEENPINNNGLVFKMKYKDMEFLFT HHHCCCCCEEEEECCCEEEECCEEEEEECCCCHHHHCCCCCCCCCEEEEEEECCEEEEEE GDIEKPAEEILKNLDIKTDILKVAHHGSSTSSSEEFIEKANPKICILQVGKNSYGLPDER CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHH VLKYLQERSIVYRTDKNGTIIVKTDGKKAYIRTVLKE HHHHHHHCCEEEEECCCCEEEEEECCCHHHHHHHHCC >Mature Secondary Structure MEFPFLYLTVALSLGIIIGRYVFYPFAFLLLLAISVAISLWGYLKNKNVSLLLLISFIFV CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH GAILSGNALNSPNPYLKFEDKFITIKGKVQEVREYEGYAKYIVKPTNLPKVLFTQYGGKY HHHHCCCCCCCCCCCEEECCEEEEEECHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCC PSDGDVVSIRGIVSIPKRATNPGGFDYKLFLKKKGIYAVMRVQGYAVDIVGKGNLNFIEK CCCCCEEEEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCEEEEEEECCCHHHHHH VIYAAKQKTEVNYINSMPERDAKFVISIFLGDKLVDDETLVQFRTAGISHIISVSGMHVA HHHHHHCCCCHHHHHCCCCCCHHEEEEEEECCEECCCHHHHHHHHHHHHHHHHHCCCHHH IITGFILYMLSLFNIRRYKVPIIIIVLTFYAILTGANPPVIRAALMASIALIGTTYGKKH HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC NSINSLSFAAFVILIFNPLMLWDVGFQLSFVATLAILYFYKPIREKLSMLNPKIRELVAL CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH TLSAQIGTIPFTMYYFHYISIISLLSNIVIVPLANIAVVLGFLSAMIGLIFPPLSYFINF HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH INIPVVEVILYITKLFNSFPYASINTIVPPLYVIVLYYGILAVLLSSFDKKTKKISIAIA HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHH LTFVIAIFFYNYLLPKDLEVTFLDVGQGDSTFVRTPHGKTFLIDGGGRPLFAISSFDVGE HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCEEEEECCCCEEEEEECCCCCC DVVLPFLYYKGVMKLDGVFISHTDIDHVGGILSILQQMKVDKIFIGIQKVTDDNFKELME HHHHHHHHHCCHHHHCCEEEECCCHHHHHHHHHHHHHHCHHHHEEEEECCCCCCHHHHHH IAKSKNIPVVFLKKGDKVKVDGVEIYVLHPDPANLIEENPINNNGLVFKMKYKDMEFLFT HHHCCCCCEEEEECCCEEEECCEEEEEECCCCHHHHCCCCCCCCCEEEEEEECCEEEEEE GDIEKPAEEILKNLDIKTDILKVAHHGSSTSSSEEFIEKANPKICILQVGKNSYGLPDER CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHH VLKYLQERSIVYRTDKNGTIIVKTDGKKAYIRTVLKE HHHHHHHCCEEEEECCCCEEEEEECCCHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]