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The map label for this gene is hrcA [H]

Identifier: 167040704

GI number: 167040704

Start: 2092018

End: 2093049

Strand: Reverse

Name: hrcA [H]

Synonym: Teth514_2081

Alternate gene names: 167040704

Gene position: 2093049-2092018 (Counterclockwise)

Preceding gene: 167040705

Following gene: 167040703

Centisome position: 85.18

GC content: 30.91

Gene sequence:

>1032_bases
ATGCCGTTAGATGATAGGAAGAAAAAAATACTATATGCGGTTATTACTGATTATATTATGACGGCAGAGCCAATAGGGTC
GAGAACAATAGCTAAGAAGTACAATATAGGATTAAGTTCTGCTACTATAAGAAACGAAATGGCGGATTTAGAAGAAATGG
GATATTTGGAGCAACCTCATACTTCTGCAGGAAGGATACCTTCAGATAAAGGATATAGATTTTATGTAGACAGCATTCTT
CGAAATTATATAAACAATGAACCTCCAATTAGTTATAATACTCGCGAGGAAATAATAGCGGAATTCGATGAGATTGTAAA
GAAATACGCAAAAATTTTGGCTAACATTACTCACCATACTACAGTTGCTAAAATGCCAAAGTTGAACCCTGATAGAATAA
AAAGAATTCAACTTATACCTGTTGCTTCTAATAAAATGATTTTTTTAGTAGTAACAGACACAGGGATTGTAAAAAATTAC
TTGCTTAATTTGTGCCAAAATGTAGATAGAACTATTTTTGAGTTTTTAAACAATTTGTTAAACGAGAAAATTGCCGGAAA
AAATGAAAAAGATGTTTTTGAGTTTTTACAACAGGATTTAAGGCATATGTTAGGAGAGATGGTTTTTATAGCCGACGAAT
TGATAAACACTATACTTTTGAGCTTGAAGCAATTACAGGAAACGGATATTTATGCGGATGGAACTTCTCATATTTTAGAT
TTTCCTGAGTATAAAGATTTAAGCAAAGCAAAAAATTTCTTCAACCTTTTAGATAACAAGTCTTTATTAAATGAAATTTT
AGAACCTGAAGTAGATTTTATAGATGTGAGAATAGGAAGCGAAAACAAGTTTGAGGAAATGAAGGACTTAAGCGTTATAA
AAACTACTTATAAGATTAACGGTCGTGTGGTGGGTACAATAGGAATTATAGGGCCTACAAGAATGGATTATAGAAAATTA
ATTAATGAAATCAATGTTATGACAAAAGAGCTTTCGAATCTTTTATCGAATATATACAATGATGAAATATAA

Upstream 100 bases:

>100_bases
CCCTAAATGAGTATTGACAAAAAATTATAAGAGTGGTATTTTAAAAACATGAATTAGCACTCAATCGAGTAGAGTGCTAA
TAATACATGGGGTGGTGAAA

Downstream 100 bases:

>100_bases
TGAGGTGATATAAGTGGAAGAAGTAGAAAAGGAAATTAACAAAGAGGAGGAAAAGGATGTTAATAATTTAGATTCAAACG
AACAAATGGAAGGACCTCCC

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPLDDRKKKILYAVITDYIMTAEPIGSRTIAKKYNIGLSSATIRNEMADLEEMGYLEQPHTSAGRIPSDKGYRFYVDSIL
RNYINNEPPISYNTREEIIAEFDEIVKKYAKILANITHHTTVAKMPKLNPDRIKRIQLIPVASNKMIFLVVTDTGIVKNY
LLNLCQNVDRTIFEFLNNLLNEKIAGKNEKDVFEFLQQDLRHMLGEMVFIADELINTILLSLKQLQETDIYADGTSHILD
FPEYKDLSKAKNFFNLLDNKSLLNEILEPEVDFIDVRIGSENKFEEMKDLSVIKTTYKINGRVVGTIGIIGPTRMDYRKL
INEINVMTKELSNLLSNIYNDEI

Sequences:

>Translated_343_residues
MPLDDRKKKILYAVITDYIMTAEPIGSRTIAKKYNIGLSSATIRNEMADLEEMGYLEQPHTSAGRIPSDKGYRFYVDSIL
RNYINNEPPISYNTREEIIAEFDEIVKKYAKILANITHHTTVAKMPKLNPDRIKRIQLIPVASNKMIFLVVTDTGIVKNY
LLNLCQNVDRTIFEFLNNLLNEKIAGKNEKDVFEFLQQDLRHMLGEMVFIADELINTILLSLKQLQETDIYADGTSHILD
FPEYKDLSKAKNFFNLLDNKSLLNEILEPEVDFIDVRIGSENKFEEMKDLSVIKTTYKINGRVVGTIGIIGPTRMDYRKL
INEINVMTKELSNLLSNIYNDEI
>Mature_342_residues
PLDDRKKKILYAVITDYIMTAEPIGSRTIAKKYNIGLSSATIRNEMADLEEMGYLEQPHTSAGRIPSDKGYRFYVDSILR
NYINNEPPISYNTREEIIAEFDEIVKKYAKILANITHHTTVAKMPKLNPDRIKRIQLIPVASNKMIFLVVTDTGIVKNYL
LNLCQNVDRTIFEFLNNLLNEKIAGKNEKDVFEFLQQDLRHMLGEMVFIADELINTILLSLKQLQETDIYADGTSHILDF
PEYKDLSKAKNFFNLLDNKSLLNEILEPEVDFIDVRIGSENKFEEMKDLSVIKTTYKINGRVVGTIGIIGPTRMDYRKLI
NEINVMTKELSNLLSNIYNDEI

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR023120
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39499; Mature: 39368

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDDRKKKILYAVITDYIMTAEPIGSRTIAKKYNIGLSSATIRNEMADLEEMGYLEQPH
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
TSAGRIPSDKGYRFYVDSILRNYINNEPPISYNTREEIIAEFDEIVKKYAKILANITHHT
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAKMPKLNPDRIKRIQLIPVASNKMIFLVVTDTGIVKNYLLNLCQNVDRTIFEFLNNLL
HHHHCCCCCHHHHCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEKIAGKNEKDVFEFLQQDLRHMLGEMVFIADELINTILLSLKQLQETDIYADGTSHILD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
FPEYKDLSKAKNFFNLLDNKSLLNEILEPEVDFIDVRIGSENKFEEMKDLSVIKTTYKIN
CCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEC
GRVVGTIGIIGPTRMDYRKLINEINVMTKELSNLLSNIYNDEI
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLDDRKKKILYAVITDYIMTAEPIGSRTIAKKYNIGLSSATIRNEMADLEEMGYLEQPH
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
TSAGRIPSDKGYRFYVDSILRNYINNEPPISYNTREEIIAEFDEIVKKYAKILANITHHT
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAKMPKLNPDRIKRIQLIPVASNKMIFLVVTDTGIVKNYLLNLCQNVDRTIFEFLNNLL
HHHHCCCCCHHHHCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEKIAGKNEKDVFEFLQQDLRHMLGEMVFIADELINTILLSLKQLQETDIYADGTSHILD
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCC
FPEYKDLSKAKNFFNLLDNKSLLNEILEPEVDFIDVRIGSENKFEEMKDLSVIKTTYKIN
CCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEC
GRVVGTIGIIGPTRMDYRKLINEINVMTKELSNLLSNIYNDEI
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA