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The map label for this gene is mraW [H]

Identifier: 167040640

GI number: 167040640

Start: 2027076

End: 2028002

Strand: Reverse

Name: mraW [H]

Synonym: Teth514_2017

Alternate gene names: 167040640

Gene position: 2028002-2027076 (Counterclockwise)

Preceding gene: 167040641

Following gene: 167040639

Centisome position: 82.53

GC content: 34.3

Gene sequence:

>927_bases
ATGGAATATAGCCATAAAAGTGTTTTGCTTAAGGAGACAATTGAATATTTAAATATAAAACCAGAGGGAATATATGTAGA
TGGTACTTTAGGTGGTGGAGGCCATTCTGAAGAAATATTAAAAAGGCTTACCACCGGAAAGTTAATTGCGATAGATAGAG
ATTTAGATGCGATAAAGGCTAGCAAAGAAAGGCTTAAAAATTACAAAAATGTAGAGTACATAAATGATAATTTTAAAAAT
ATAAAAGAGATACTTAAAAGTTTGAATATTGACAAGGTTGATGGCATCCTTTTGGATTTGGGGGTATCTTCTTATCAATT
AGAAGAAGTTAAACGGGGTTTTTCTTATATGAAAGATGCTCCGATGGATATGAGAATGGACAAAAATTCACCTTTTTCTG
CCTATGATGTGGTGAACAAGTATTCACAGCAAGAATTAGAAAGAGTGATAAGAGAATATGGAGAAGAGAAATGGGCATCA
CGTATTGCTAAATTTATTGTAAAAGAAAGAGAAAAAGGAGAAATAAAAACTACTTTTCAGTTAGTAGAGATTATAAAAAA
CGCTATTCCTGCCTCTGCCAGGAGAGAAGGACCACATCCAGCAAAAAGAACATTTCAAGCCATACGAATAGAAGTCAATG
AAGAACTTAAAGGTTTAGATAAGGCGATTGAGGATATGGTAGAGGTATTACGGGGGAAAGGGCGCATTGCGATAATCACA
TTTCACTCTTTGGAAGATAGAATTGTGAAGAATACTTTTAAAAAATTAGAAAATCCCTGCACTTGTCCACCTAATATGCC
ATGTACTTGTGGTAAAAAACCGGTAGTGAAGATTATAACAAAAAAACCGGTACTACCTTCCAAAGAGGAAATAGAAACAA
ATTCCAGGTCCCGTAGTGCAAAACTTAGAGTTGCGGAAAAACTGTAA

Upstream 100 bases:

>100_bases
GAGTAAAGAGGTTTGGGAAGAATACTCTAACAATACAGATGTTTCTTTTGAAGAGATTGCTGAGCATCTTGACGACTTAA
ATATATAGGTGTGATAAAGA

Downstream 100 bases:

>100_bases
GTTCTAAAAGAAATGGAGGTAGAATAAATTGATAGTAGCACAAAGAGAATATAATTACGAGTATCCCCCATATACCTCAG
AAAAGAAAGAGCAAGTAAGA

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MEYSHKSVLLKETIEYLNIKPEGIYVDGTLGGGGHSEEILKRLTTGKLIAIDRDLDAIKASKERLKNYKNVEYINDNFKN
IKEILKSLNIDKVDGILLDLGVSSYQLEEVKRGFSYMKDAPMDMRMDKNSPFSAYDVVNKYSQQELERVIREYGEEKWAS
RIAKFIVKEREKGEIKTTFQLVEIIKNAIPASARREGPHPAKRTFQAIRIEVNEELKGLDKAIEDMVEVLRGKGRIAIIT
FHSLEDRIVKNTFKKLENPCTCPPNMPCTCGKKPVVKIITKKPVLPSKEEIETNSRSRSAKLRVAEKL

Sequences:

>Translated_308_residues
MEYSHKSVLLKETIEYLNIKPEGIYVDGTLGGGGHSEEILKRLTTGKLIAIDRDLDAIKASKERLKNYKNVEYINDNFKN
IKEILKSLNIDKVDGILLDLGVSSYQLEEVKRGFSYMKDAPMDMRMDKNSPFSAYDVVNKYSQQELERVIREYGEEKWAS
RIAKFIVKEREKGEIKTTFQLVEIIKNAIPASARREGPHPAKRTFQAIRIEVNEELKGLDKAIEDMVEVLRGKGRIAIIT
FHSLEDRIVKNTFKKLENPCTCPPNMPCTCGKKPVVKIITKKPVLPSKEEIETNSRSRSAKLRVAEKL
>Mature_308_residues
MEYSHKSVLLKETIEYLNIKPEGIYVDGTLGGGGHSEEILKRLTTGKLIAIDRDLDAIKASKERLKNYKNVEYINDNFKN
IKEILKSLNIDKVDGILLDLGVSSYQLEEVKRGFSYMKDAPMDMRMDKNSPFSAYDVVNKYSQQELERVIREYGEEKWAS
RIAKFIVKEREKGEIKTTFQLVEIIKNAIPASARREGPHPAKRTFQAIRIEVNEELKGLDKAIEDMVEVLRGKGRIAIIT
FHSLEDRIVKNTFKKLENPCTCPPNMPCTCGKKPVVKIITKKPVLPSKEEIETNSRSRSAKLRVAEKL

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=337, Percent_Identity=35.3115727002967, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI165377202, Length=188, Percent_Identity=37.7659574468085, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1786270, Length=314, Percent_Identity=41.0828025477707, Blast_Score=230, Evalue=1e-61,
Organism=Drosophila melanogaster, GI62472493, Length=328, Percent_Identity=36.5853658536585, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI28571637, Length=328, Percent_Identity=36.5853658536585, Blast_Score=181, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 35187; Mature: 35187

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYSHKSVLLKETIEYLNIKPEGIYVDGTLGGGGHSEEILKRLTTGKLIAIDRDLDAIKA
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHH
SKERLKNYKNVEYINDNFKNIKEILKSLNIDKVDGILLDLGVSSYQLEEVKRGFSYMKDA
HHHHHHHCCCCHHHHCCHHHHHHHHHHCCCCHHCCEEEECCCCHHHHHHHHHHHHHHHCC
PMDMRMDKNSPFSAYDVVNKYSQQELERVIREYGEEKWASRIAKFIVKEREKGEIKTTFQ
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVEIIKNAIPASARREGPHPAKRTFQAIRIEVNEELKGLDKAIEDMVEVLRGKGRIAIIT
HHHHHHHHCCCCHHCCCCCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
FHSLEDRIVKNTFKKLENPCTCPPNMPCTCGKKPVVKIITKKPVLPSKEEIETNSRSRSA
ECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCHHHHHCCCCCHHH
KLRVAEKL
HHHHHHCC
>Mature Secondary Structure
MEYSHKSVLLKETIEYLNIKPEGIYVDGTLGGGGHSEEILKRLTTGKLIAIDRDLDAIKA
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHH
SKERLKNYKNVEYINDNFKNIKEILKSLNIDKVDGILLDLGVSSYQLEEVKRGFSYMKDA
HHHHHHHCCCCHHHHCCHHHHHHHHHHCCCCHHCCEEEECCCCHHHHHHHHHHHHHHHCC
PMDMRMDKNSPFSAYDVVNKYSQQELERVIREYGEEKWASRIAKFIVKEREKGEIKTTFQ
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVEIIKNAIPASARREGPHPAKRTFQAIRIEVNEELKGLDKAIEDMVEVLRGKGRIAIIT
HHHHHHHHCCCCHHCCCCCHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
FHSLEDRIVKNTFKKLENPCTCPPNMPCTCGKKPVVKIITKKPVLPSKEEIETNSRSRSA
ECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCHHHHHCCCCCHHH
KLRVAEKL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA