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The map label for this gene is spoVD [H]

Identifier: 167040638

GI number: 167040638

Start: 2024516

End: 2026465

Strand: Reverse

Name: spoVD [H]

Synonym: Teth514_2015

Alternate gene names: 167040638

Gene position: 2026465-2024516 (Counterclockwise)

Preceding gene: 167040639

Following gene: 167040637

Centisome position: 82.47

GC content: 36.05

Gene sequence:

>1950_bases
ATGGCACTTCCTCAATGGACTTTAGAAGTATCTGTTAGTGGTAAAAGGGGAAATATATTTGATAGAAATGGCAAAGTATT
AGCAGAAAATATAAGTGTTAATAAAATAAGTGTTATCCCTAAAGAAATACCTGATTCTCAAAGAGAAGCAGTAGCTGAAG
CTTTAGCCCAAATATTAAATTTAGATAAAGGAAAAGTTCTTCAAAAGATTTCTAATAAAAACTTACAAGAAGTGTTAATT
GCTAAACAAGTTGATGACGAAAAGGTAGCAGAGATAAGAAAGCTTAATATAGATGGAATAATAATTTCTGAGGACATGAA
AAGATTCTATCCCAATAATACTCTTGCATCACATGTCTTGGGTTTTACTGGAATTGACAACCAGGGTTTAGATGGCGTTG
AATTAGCATTTGACAACTTTTTAAGAGGTATTCCGGGAAGAATTTTTACTCCAATGGATGCTATAGGTAGAAAGATGGAT
GTGGGAGAGGAAGAGTATTTTGAACCTCTTCCAGGTTATAACGTAGTGCTTACAATAGATGAAACTATTCAGCATTTTGC
AGAAAAGGCTCTTAACCAAGCGATGGTTCATTCTAAGCCTTCAAAAGGAGCAGTAGCCATTGTTATGGACCCCAAAACAG
GGGAAATATTGGCTTTGGCTAATAGACCAAATTTTAATCCTAATAATCCTTTTGAAGGACCGCAGGAAGAATGGTATAAA
GTTTGGCGAAATAAAGCTATTTCTGATTCTTATGAACCTGGTTCTGTTTTTAAGACAATTACTGCTTCTGCAGCTTTAGA
AGAAAAACTTGTAGGTCTTAATGAACAGTTTTATTGTCCGGGCTATACTATAGTTTCTGGACATAGAATAAATTGCTGGG
CTACCCATGGCAGTGAAAATTTTGTTCAAGGTGTTCAAAATTCTTGCAACGCAGTTTTTGTGACGTTAGGACAAAGGCTA
GGAGTAGAAAAACTCTATAAATACATACATGATTTTGGATTTGGACAAAGGACAGGAATACTTCTTCCTGGTGAAGCTCC
AGGTCTTGTATTGGCAGAAAGTAGTGTTGGGCCTGTTGAGTTAGCCACTAATTCTTTTGGGCAAGGTATTGCTGTGACGC
CTCTTCAGATGATTACTGCTGTCTCCGCAATAGCCAATGGAGGAAAATTGATGCAACCTCTAATTGTGAAATCAATTGTA
GATTCAAATGGAAAAGTAGTGAAGGAATTTAAACCAAAAGTAGTGAGGCAAGTCATTTCTGAACAGACCTCTTCTACAAT
GAGAGAAATACTAAAAAGTGTAGTGTCAGAGGGAACAGGCAAAGCAGGATATATTGAAGGATTTGATGTAGCTGGAAAGA
CTGGTACTACAGAAAAATATATGCCAGGCAAATATGTGGCATCTTTTATAGGTTTTGCACCAGCGGAGGATCCAAAAGTT
ATTGTGTTGGTGGTAATAGATGAGCCTAATAATCCGGAAACCCATTTTGGAAGCCAATTGGCTGCACCTGTAGTAAAGAG
TATTTTAGAAGATACCTTAAGATATTTGGAAGTACAGCCAAGAGGAATAGAAAAACCTGCATCAGTTGTAGTACCGGATG
TGAGGAATATGAAACTTTATGAAGCAGAAAACATTATTTTATCGAATAAGCTTAACTTTATTATAGAAGGAAATGGAGAT
ACTGTTTTTGACCAAATGCCTAAACCAGGAGCAATTGTAGAAGAAAACACACAAGTTATTTTGTACTTAAATGCTGAAAA
AATACAAGAGGTAGTAGTTCCTGATTTAACTGGTAAAAGCGTAAAAGAAGCTACAGAAATTTTAAATTCTTTGGGGCTTA
AAATAAGAATAAAAGGCAGCGGTTTTGCTGTGAATCAAAGTCCGAAAGAAGGCACGATTTTGAAAAAAGGCGAAACTGTA
GAAGTGGAGTTTAGGCCTAAGGAAAAATAA

Upstream 100 bases:

>100_bases
AAGAATTCTTTTTTTACTTTTTTTATCTTCTATAGTAGTTTTTGGACTTATACTCAGACTTTTTTGGATACAGGTAGTAA
AAAGTGAAGATTATCAAAAG

Downstream 100 bases:

>100_bases
ACTTCCTCTATGCAAAATCTATAATTGTGCTATACTATTTAGTGGTGGTATGCTTTTTAGATATTTTTGTGAGGAGGCCT
AACATGAAACTAATAGATAT

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MALPQWTLEVSVSGKRGNIFDRNGKVLAENISVNKISVIPKEIPDSQREAVAEALAQILNLDKGKVLQKISNKNLQEVLI
AKQVDDEKVAEIRKLNIDGIIISEDMKRFYPNNTLASHVLGFTGIDNQGLDGVELAFDNFLRGIPGRIFTPMDAIGRKMD
VGEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDPKTGEILALANRPNFNPNNPFEGPQEEWYK
VWRNKAISDSYEPGSVFKTITASAALEEKLVGLNEQFYCPGYTIVSGHRINCWATHGSENFVQGVQNSCNAVFVTLGQRL
GVEKLYKYIHDFGFGQRTGILLPGEAPGLVLAESSVGPVELATNSFGQGIAVTPLQMITAVSAIANGGKLMQPLIVKSIV
DSNGKVVKEFKPKVVRQVISEQTSSTMREILKSVVSEGTGKAGYIEGFDVAGKTGTTEKYMPGKYVASFIGFAPAEDPKV
IVLVVIDEPNNPETHFGSQLAAPVVKSILEDTLRYLEVQPRGIEKPASVVVPDVRNMKLYEAENIILSNKLNFIIEGNGD
TVFDQMPKPGAIVEENTQVILYLNAEKIQEVVVPDLTGKSVKEATEILNSLGLKIRIKGSGFAVNQSPKEGTILKKGETV
EVEFRPKEK

Sequences:

>Translated_649_residues
MALPQWTLEVSVSGKRGNIFDRNGKVLAENISVNKISVIPKEIPDSQREAVAEALAQILNLDKGKVLQKISNKNLQEVLI
AKQVDDEKVAEIRKLNIDGIIISEDMKRFYPNNTLASHVLGFTGIDNQGLDGVELAFDNFLRGIPGRIFTPMDAIGRKMD
VGEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDPKTGEILALANRPNFNPNNPFEGPQEEWYK
VWRNKAISDSYEPGSVFKTITASAALEEKLVGLNEQFYCPGYTIVSGHRINCWATHGSENFVQGVQNSCNAVFVTLGQRL
GVEKLYKYIHDFGFGQRTGILLPGEAPGLVLAESSVGPVELATNSFGQGIAVTPLQMITAVSAIANGGKLMQPLIVKSIV
DSNGKVVKEFKPKVVRQVISEQTSSTMREILKSVVSEGTGKAGYIEGFDVAGKTGTTEKYMPGKYVASFIGFAPAEDPKV
IVLVVIDEPNNPETHFGSQLAAPVVKSILEDTLRYLEVQPRGIEKPASVVVPDVRNMKLYEAENIILSNKLNFIIEGNGD
TVFDQMPKPGAIVEENTQVILYLNAEKIQEVVVPDLTGKSVKEATEILNSLGLKIRIKGSGFAVNQSPKEGTILKKGETV
EVEFRPKEK
>Mature_648_residues
ALPQWTLEVSVSGKRGNIFDRNGKVLAENISVNKISVIPKEIPDSQREAVAEALAQILNLDKGKVLQKISNKNLQEVLIA
KQVDDEKVAEIRKLNIDGIIISEDMKRFYPNNTLASHVLGFTGIDNQGLDGVELAFDNFLRGIPGRIFTPMDAIGRKMDV
GEEEYFEPLPGYNVVLTIDETIQHFAEKALNQAMVHSKPSKGAVAIVMDPKTGEILALANRPNFNPNNPFEGPQEEWYKV
WRNKAISDSYEPGSVFKTITASAALEEKLVGLNEQFYCPGYTIVSGHRINCWATHGSENFVQGVQNSCNAVFVTLGQRLG
VEKLYKYIHDFGFGQRTGILLPGEAPGLVLAESSVGPVELATNSFGQGIAVTPLQMITAVSAIANGGKLMQPLIVKSIVD
SNGKVVKEFKPKVVRQVISEQTSSTMREILKSVVSEGTGKAGYIEGFDVAGKTGTTEKYMPGKYVASFIGFAPAEDPKVI
VLVVIDEPNNPETHFGSQLAAPVVKSILEDTLRYLEVQPRGIEKPASVVVPDVRNMKLYEAENIILSNKLNFIIEGNGDT
VFDQMPKPGAIVEENTQVILYLNAEKIQEVVVPDLTGKSVKEATEILNSLGLKIRIKGSGFAVNQSPKEGTILKKGETVE
VEFRPKEK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=519, Percent_Identity=32.5626204238921, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1786854, Length=590, Percent_Identity=22.5423728813559, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 70964; Mature: 70833

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPQWTLEVSVSGKRGNIFDRNGKVLAENISVNKISVIPKEIPDSQREAVAEALAQILN
CCCCCEEEEEEEECCCCCEECCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
LDKGKVLQKISNKNLQEVLIAKQVDDEKVAEIRKLNIDGIIISEDMKRFYPNNTLASHVL
CCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHCCCCHHHHHHH
GFTGIDNQGLDGVELAFDNFLRGIPGRIFTPMDAIGRKMDVGEEEYFEPLPGYNVVLTID
CCCCCCCCCCCHHHHHHHHHHHCCCCCEECCHHHHCCCCCCCCHHHCCCCCCCEEEEEEH
ETIQHFAEKALNQAMVHSKPSKGAVAIVMDPKTGEILALANRPNFNPNNPFEGPQEEWYK
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHH
VWRNKAISDSYEPGSVFKTITASAALEEKLVGLNEQFYCPGYTIVSGHRINCWATHGSEN
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCEEEEEEECCCHH
FVQGVQNSCNAVFVTLGQRLGVEKLYKYIHDFGFGQRTGILLPGEAPGLVLAESSVGPVE
HHHHHHCCCCEEEEEHHHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCCEE
LATNSFGQGIAVTPLQMITAVSAIANGGKLMQPLIVKSIVDSNGKVVKEFKPKVVRQVIS
EECCCCCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EQTSSTMREILKSVVSEGTGKAGYIEGFDVAGKTGTTEKYMPGKYVASFIGFAPAEDPKV
HHHHHHHHHHHHHHHHCCCCCCCCEECEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCE
IVLVVIDEPNNPETHFGSQLAAPVVKSILEDTLRYLEVQPRGIEKPASVVVPDVRNMKLY
EEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEECCCCCCEEEE
EAENIILSNKLNFIIEGNGDTVFDQMPKPGAIVEENTQVILYLNAEKIQEVVVPDLTGKS
ECCCEEEECCEEEEEECCCCCHHHCCCCCCCEEECCCEEEEEECHHHHHHHHCCCCCCCH
VKEATEILNSLGLKIRIKGSGFAVNQSPKEGTILKKGETVEVEFRPKEK
HHHHHHHHHHCCCEEEECCCCEEECCCCCCCCEEECCCEEEEEECCCCC
>Mature Secondary Structure 
ALPQWTLEVSVSGKRGNIFDRNGKVLAENISVNKISVIPKEIPDSQREAVAEALAQILN
CCCCEEEEEEEECCCCCEECCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
LDKGKVLQKISNKNLQEVLIAKQVDDEKVAEIRKLNIDGIIISEDMKRFYPNNTLASHVL
CCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHCCCCHHHHHHH
GFTGIDNQGLDGVELAFDNFLRGIPGRIFTPMDAIGRKMDVGEEEYFEPLPGYNVVLTID
CCCCCCCCCCCHHHHHHHHHHHCCCCCEECCHHHHCCCCCCCCHHHCCCCCCCEEEEEEH
ETIQHFAEKALNQAMVHSKPSKGAVAIVMDPKTGEILALANRPNFNPNNPFEGPQEEWYK
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCHHHHHH
VWRNKAISDSYEPGSVFKTITASAALEEKLVGLNEQFYCPGYTIVSGHRINCWATHGSEN
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCEEEECCCEEEEEEECCCHH
FVQGVQNSCNAVFVTLGQRLGVEKLYKYIHDFGFGQRTGILLPGEAPGLVLAESSVGPVE
HHHHHHCCCCEEEEEHHHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCCEE
LATNSFGQGIAVTPLQMITAVSAIANGGKLMQPLIVKSIVDSNGKVVKEFKPKVVRQVIS
EECCCCCCCEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EQTSSTMREILKSVVSEGTGKAGYIEGFDVAGKTGTTEKYMPGKYVASFIGFAPAEDPKV
HHHHHHHHHHHHHHHHCCCCCCCCEECEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCE
IVLVVIDEPNNPETHFGSQLAAPVVKSILEDTLRYLEVQPRGIEKPASVVVPDVRNMKLY
EEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEECCCCCCEEEE
EAENIILSNKLNFIIEGNGDTVFDQMPKPGAIVEENTQVILYLNAEKIQEVVVPDLTGKS
ECCCEEEECCEEEEEECCCCCHHHCCCCCCCEEECCCEEEEEECHHHHHHHHCCCCCCCH
VKEATEILNSLGLKIRIKGSGFAVNQSPKEGTILKKGETVEVEFRPKEK
HHHHHHHHHHCCCEEEECCCCEEECCCCCCCCEEECCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]