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The map label for this gene is xseA [H]

Identifier: 167040174

GI number: 167040174

Start: 1558787

End: 1559992

Strand: Direct

Name: xseA [H]

Synonym: Teth514_1536

Alternate gene names: 167040174

Gene position: 1558787-1559992 (Clockwise)

Preceding gene: 167040173

Following gene: 167040175

Centisome position: 63.44

GC content: 32.5

Gene sequence:

>1206_bases
ATGCAGTTAAAGGCGCTTGAAGTCAGAGAAATTACAGACTATATCAAAAAAATGATGGATAATGATATAATTTTGAGAAA
TGTGCGGGTTAAAGGAGAAATTTCTAATTTGAAATACCATAGCACAGGAATATATTTCACTTTGAAAGATGAAATAGCCT
CTTTAAAATGTGTGATGTTTAATGAATATGGAAAGCTTTTAAATTTTACTTTGCAAGATGGTATGTCAGTGATTGTGACA
GGTAGAATATCTGTATATGAAAGAAATGGAACTTATCAACTGTACGCTCAAAGTATACAGTCGGATGGAATTGGAGCTTT
ATACTTTGCTTTTAATAAACTTAAAGAGAAACTGCAAAAAGAAGGACTTTTTGATTCTGATAAAAAGAAACCTATCCCTA
AACATCCTAAAAAAATTGCTGTGGTGACTTCTCCAACAGGGGCTGTAATACGAGATATAATAACAATTTCGAGAAGGAGA
AATCCAACAGTAGACATTTTAGTAGTTCCAGTTTTGGTACAAGGTAGTTCGGCAGCGGATGAAATATGCAACGCTTTTCG
AATTTTGAACAAAAGGGAAGACATTGATGTAATTATTTTAGCAAGGGGTGGAGGTTCATTAGAAGAAATTTGGCCTTTCA
ATGAAGAAAAAGTGGCAAGATGCATTTATGCATCTCGCATACCAGTTGTTTCTGCAGTAGGGCATGAGACAGACTTTACT
ATTTCTGATTTTGTGGCGGATTTGAGAGCTCCTACCCCTTCTGCAGCTGCTGAAATTGTAGTACCAGACATAAAAGTTTA
CCAAAGGGAATTGTTTTTATTAAAAACGAAATTATTAACATTGATGACTGCTGAATTAAATCGCAAGAAAAAAGAATTTG
AAGGGCTTAAAAGGGCTTTGTATCTTAATAGCCCCACTAAGAAAAGTGAAATTTTAAGGCATAAAGTTGAAAATTTAACA
GCCTCTTTATACAATGAAATGCTTTCTATATACCAGCATAAAAGAAATGATTTTTTAATTTTAGCAGAAAAGTTGAATTC
TTTAAGTCCTTTAAAAGTACTTACAAGAGGTTATACAATTGTTTTAGATAAGCAAGAAAAAGTTATTTCTTCTGTGAGAG
ATATAAAACCTTATGATGAAATAAAAATCTTATTTAAAGATGGCAAAGCTAAAGCGATTGTACAAGAGGTGAAAGAGAAT
GAATGA

Upstream 100 bases:

>100_bases
AGTGTAAAAGACCTGTGTTCTTACGTAACACCAGTTCCAGGAGGAGTTGGACCTGTGACGACAGCTATGATACTTAAAAA
TACCCTGGAGGCTTTTAAAT

Downstream 100 bases:

>100_bases
GGAATTGACTTTTGAAGAAGAAATGATGAGATTAGAAGAAATTGTAAATACACTAGAAAAAGGAAATTTAATGTTGGAAG
AGTCTTTTAACTTGTTTAAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MQLKALEVREITDYIKKMMDNDIILRNVRVKGEISNLKYHSTGIYFTLKDEIASLKCVMFNEYGKLLNFTLQDGMSVIVT
GRISVYERNGTYQLYAQSIQSDGIGALYFAFNKLKEKLQKEGLFDSDKKKPIPKHPKKIAVVTSPTGAVIRDIITISRRR
NPTVDILVVPVLVQGSSAADEICNAFRILNKREDIDVIILARGGGSLEEIWPFNEEKVARCIYASRIPVVSAVGHETDFT
ISDFVADLRAPTPSAAAEIVVPDIKVYQRELFLLKTKLLTLMTAELNRKKKEFEGLKRALYLNSPTKKSEILRHKVENLT
ASLYNEMLSIYQHKRNDFLILAEKLNSLSPLKVLTRGYTIVLDKQEKVISSVRDIKPYDEIKILFKDGKAKAIVQEVKEN
E

Sequences:

>Translated_401_residues
MQLKALEVREITDYIKKMMDNDIILRNVRVKGEISNLKYHSTGIYFTLKDEIASLKCVMFNEYGKLLNFTLQDGMSVIVT
GRISVYERNGTYQLYAQSIQSDGIGALYFAFNKLKEKLQKEGLFDSDKKKPIPKHPKKIAVVTSPTGAVIRDIITISRRR
NPTVDILVVPVLVQGSSAADEICNAFRILNKREDIDVIILARGGGSLEEIWPFNEEKVARCIYASRIPVVSAVGHETDFT
ISDFVADLRAPTPSAAAEIVVPDIKVYQRELFLLKTKLLTLMTAELNRKKKEFEGLKRALYLNSPTKKSEILRHKVENLT
ASLYNEMLSIYQHKRNDFLILAEKLNSLSPLKVLTRGYTIVLDKQEKVISSVRDIKPYDEIKILFKDGKAKAIVQEVKEN
E
>Mature_401_residues
MQLKALEVREITDYIKKMMDNDIILRNVRVKGEISNLKYHSTGIYFTLKDEIASLKCVMFNEYGKLLNFTLQDGMSVIVT
GRISVYERNGTYQLYAQSIQSDGIGALYFAFNKLKEKLQKEGLFDSDKKKPIPKHPKKIAVVTSPTGAVIRDIITISRRR
NPTVDILVVPVLVQGSSAADEICNAFRILNKREDIDVIILARGGGSLEEIWPFNEEKVARCIYASRIPVVSAVGHETDFT
ISDFVADLRAPTPSAAAEIVVPDIKVYQRELFLLKTKLLTLMTAELNRKKKEFEGLKRALYLNSPTKKSEILRHKVENLT
ASLYNEMLSIYQHKRNDFLILAEKLNSLSPLKVLTRGYTIVLDKQEKVISSVRDIKPYDEIKILFKDGKAKAIVQEVKEN
E

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=418, Percent_Identity=34.9282296650718, Blast_Score=262, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45546; Mature: 45546

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKALEVREITDYIKKMMDNDIILRNVRVKGEISNLKYHSTGIYFTLKDEIASLKCVMF
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCEEEECCEEEEEECCCCCCEEEEEE
NEYGKLLNFTLQDGMSVIVTGRISVYERNGTYQLYAQSIQSDGIGALYFAFNKLKEKLQK
HHHHHHHEEEHHCCCEEEEEEEEEEEEECCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHH
EGLFDSDKKKPIPKHPKKIAVVTSPTGAVIRDIITISRRRNPTVDILVVPVLVQGSSAAD
CCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHH
EICNAFRILNKREDIDVIILARGGGSLEEIWPFNEEKVARCIYASRIPVVSAVGHETDFT
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCC
ISDFVADLRAPTPSAAAEIVVPDIKVYQRELFLLKTKLLTLMTAELNRKKKEFEGLKRAL
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YLNSPTKKSEILRHKVENLTASLYNEMLSIYQHKRNDFLILAEKLNSLSPLKVLTRGYTI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHCCEEE
VLDKQEKVISSVRDIKPYDEIKILFKDGKAKAIVQEVKENE
EEECHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MQLKALEVREITDYIKKMMDNDIILRNVRVKGEISNLKYHSTGIYFTLKDEIASLKCVMF
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCEEEECCEEEEEECCCCCCEEEEEE
NEYGKLLNFTLQDGMSVIVTGRISVYERNGTYQLYAQSIQSDGIGALYFAFNKLKEKLQK
HHHHHHHEEEHHCCCEEEEEEEEEEEEECCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHH
EGLFDSDKKKPIPKHPKKIAVVTSPTGAVIRDIITISRRRNPTVDILVVPVLVQGSSAAD
CCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHH
EICNAFRILNKREDIDVIILARGGGSLEEIWPFNEEKVARCIYASRIPVVSAVGHETDFT
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCC
ISDFVADLRAPTPSAAAEIVVPDIKVYQRELFLLKTKLLTLMTAELNRKKKEFEGLKRAL
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YLNSPTKKSEILRHKVENLTASLYNEMLSIYQHKRNDFLILAEKLNSLSPLKVLTRGYTI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHCCEEE
VLDKQEKVISSVRDIKPYDEIKILFKDGKAKAIVQEVKENE
EEECHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA