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The map label for this gene is aspS [H]

Identifier: 167040111

GI number: 167040111

Start: 1506255

End: 1508033

Strand: Direct

Name: aspS [H]

Synonym: Teth514_1473

Alternate gene names: 167040111

Gene position: 1506255-1508033 (Clockwise)

Preceding gene: 167040110

Following gene: 167040112

Centisome position: 61.3

GC content: 35.3

Gene sequence:

>1779_bases
ATGGGAGAACAATTAAATGGACTTAAAAGAACTCACATGTGTGGAGAATTGACAGTTGAAGACGTAGATAAATATGTTGT
AGTTATGGGATGGGTACAAAGGAGAAGAGACCATGGAGGATTAGTGTTTATAGATTTAAGAGATAGAACAGGCATTGTGC
AGGTGGTTTTTAGCAATGAGGTTTCTTCTGAAGCTTTTGAAAAAGTGCAAAGTGTAAGAAGTGAATACGTCCTTGCAATA
GAGGGAAAAGTGGTAAAAAGGTCACCTGAAAATGTAAATCCTAAAATTTCTACAGGAGAAATTGAAATATATGCCAATAC
TTTAAAAATTTTAAGTAAATCAGAAACTCCGCCTTTCCCAATAGAGGATAGGAGCAATGTATCAGAGGCCGTAAGGTTAA
AATACAGGTATTTAGATTTGAGAAGACCTTCAATGCAGAAAAATTTGATGACTCGGTTTAAAATAACTAAAGTTGTTCGT
GACTTTTTGAATAAAAATGGTTTTATAGAGATAGAAACGCCTCTTTTAATTAAAAGTACGCCAGAAGGTGCAAGAGATTA
CCTCGTACCAAGTAGAATTTATCCAGGAAAATTTTATGCTTTGCCGCAATCTCCTCAAATATTCAAACAACTTCTTATGA
TTTCTGGATTTGATAAATATTACCAAATTGCTAAGTGTTTAAGAGATGAGGATTTGAGGGCAGATAGGCAACCAGAGTTT
ACACAAATAGATATAGAAATGTCTTTTGTAGAAGTAGAAGATGTTTTGAAAATTAACGAAAAAATGATTGCAGAGATATT
TAAAGAGACTTTAGGCATTGATGTACCAATTCCTTTTAAAAGATTATCTTATCAAGAATCCATGGAAAGATTTGGGACAG
ATAAACCAGACTTGAGGTTTGGAATGGAACTTAAGGATTTATCTGATATAGTGGCACAATCAGAATTTAATGTGTTTAAG
ACTGCTTTAAAAAATAACGGTTCTGTGAGAGGTATAAATGTAAAAGGTGCTGCTTCTATGCCAAGAAGACAGTTGGACGA
ACTGGTAGAGTTTGCAAAAACTTATGGCGCTAAAGGACTTTTGTGGATACAAGTTTTTGAAAAGGAAGTGAAATCTCCTG
CTACTAAATTTTTAAGTGAAGAAGAAATGAAGAAAATACTCGAAAGACTTGAGGCAGAAGCCGGAGATTTGCTACTAATT
GTGGCAGACAAAGATGAAATAGTTTTTGATACTTTAGCTCATTTGAGGCTAGAGCTTGGCAAGAGATTTAATTTAATTGA
TGAGAATAAATATGAGTTTGTTTGGATAGTAGATTTTCCACTTTTAGAGTACGACGAAGGAGAAAAAAGGTATGTAGCAA
AGCACCATCCTTTTACTGCTCCTAAAGATGAAGATATAGAGCTACTGGAAAAGGAACCTTTAAAAGTCAGGGCAAAGGCT
TATGACATAGTTTTAAATGGTACAGAGATTGGTGGAGGAAGTATAAGGATACACGATACTGAGCTTCAAAAAAGAATGTT
TAAAGTTTTGGGATTTAGCGAAGAAAAAGCGTGGGAAAGATTTGGATTTTTGATGGAGGCTTTCAAATACGGTGCTCCTC
CCCATGGAGGTATAGCTTATGGGTTGGATAGGCTTGCAATGATTATAACGGGAAGCGACACCATAAGGGATGTAATTGCA
TTTCCAAAGACTCAAAATGCAGTGTGCTTGATGACAGATGCTCCTTCTGAGGTTTCAGAAGAGCAGTTAAAGGAATTGCA
CATAAAGGTAGACCTATAA

Upstream 100 bases:

>100_bases
ACAAAGTTAAATTGAAAAATATGAGAGATGGAAGCGAAGTAGAAATATCCATTGATGAGATAGAACAAAGGATAAAAAAT
ATATAAACGGAGGGAGTTAA

Downstream 100 bases:

>100_bases
ACGTTTACCAGTTGAAAAATAGAGGCTTTTGTGCTATTATTTATATAGAAATATGAATAAAGTTGAAAAGCCCTGTGGTG
TACGTGAGGTCCGGTGAAAG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MGEQLNGLKRTHMCGELTVEDVDKYVVVMGWVQRRRDHGGLVFIDLRDRTGIVQVVFSNEVSSEAFEKVQSVRSEYVLAI
EGKVVKRSPENVNPKISTGEIEIYANTLKILSKSETPPFPIEDRSNVSEAVRLKYRYLDLRRPSMQKNLMTRFKITKVVR
DFLNKNGFIEIETPLLIKSTPEGARDYLVPSRIYPGKFYALPQSPQIFKQLLMISGFDKYYQIAKCLRDEDLRADRQPEF
TQIDIEMSFVEVEDVLKINEKMIAEIFKETLGIDVPIPFKRLSYQESMERFGTDKPDLRFGMELKDLSDIVAQSEFNVFK
TALKNNGSVRGINVKGAASMPRRQLDELVEFAKTYGAKGLLWIQVFEKEVKSPATKFLSEEEMKKILERLEAEAGDLLLI
VADKDEIVFDTLAHLRLELGKRFNLIDENKYEFVWIVDFPLLEYDEGEKRYVAKHHPFTAPKDEDIELLEKEPLKVRAKA
YDIVLNGTEIGGGSIRIHDTELQKRMFKVLGFSEEKAWERFGFLMEAFKYGAPPHGGIAYGLDRLAMIITGSDTIRDVIA
FPKTQNAVCLMTDAPSEVSEEQLKELHIKVDL

Sequences:

>Translated_592_residues
MGEQLNGLKRTHMCGELTVEDVDKYVVVMGWVQRRRDHGGLVFIDLRDRTGIVQVVFSNEVSSEAFEKVQSVRSEYVLAI
EGKVVKRSPENVNPKISTGEIEIYANTLKILSKSETPPFPIEDRSNVSEAVRLKYRYLDLRRPSMQKNLMTRFKITKVVR
DFLNKNGFIEIETPLLIKSTPEGARDYLVPSRIYPGKFYALPQSPQIFKQLLMISGFDKYYQIAKCLRDEDLRADRQPEF
TQIDIEMSFVEVEDVLKINEKMIAEIFKETLGIDVPIPFKRLSYQESMERFGTDKPDLRFGMELKDLSDIVAQSEFNVFK
TALKNNGSVRGINVKGAASMPRRQLDELVEFAKTYGAKGLLWIQVFEKEVKSPATKFLSEEEMKKILERLEAEAGDLLLI
VADKDEIVFDTLAHLRLELGKRFNLIDENKYEFVWIVDFPLLEYDEGEKRYVAKHHPFTAPKDEDIELLEKEPLKVRAKA
YDIVLNGTEIGGGSIRIHDTELQKRMFKVLGFSEEKAWERFGFLMEAFKYGAPPHGGIAYGLDRLAMIITGSDTIRDVIA
FPKTQNAVCLMTDAPSEVSEEQLKELHIKVDL
>Mature_591_residues
GEQLNGLKRTHMCGELTVEDVDKYVVVMGWVQRRRDHGGLVFIDLRDRTGIVQVVFSNEVSSEAFEKVQSVRSEYVLAIE
GKVVKRSPENVNPKISTGEIEIYANTLKILSKSETPPFPIEDRSNVSEAVRLKYRYLDLRRPSMQKNLMTRFKITKVVRD
FLNKNGFIEIETPLLIKSTPEGARDYLVPSRIYPGKFYALPQSPQIFKQLLMISGFDKYYQIAKCLRDEDLRADRQPEFT
QIDIEMSFVEVEDVLKINEKMIAEIFKETLGIDVPIPFKRLSYQESMERFGTDKPDLRFGMELKDLSDIVAQSEFNVFKT
ALKNNGSVRGINVKGAASMPRRQLDELVEFAKTYGAKGLLWIQVFEKEVKSPATKFLSEEEMKKILERLEAEAGDLLLIV
ADKDEIVFDTLAHLRLELGKRFNLIDENKYEFVWIVDFPLLEYDEGEKRYVAKHHPFTAPKDEDIELLEKEPLKVRAKAY
DIVLNGTEIGGGSIRIHDTELQKRMFKVLGFSEEKAWERFGFLMEAFKYGAPPHGGIAYGLDRLAMIITGSDTIRDVIAF
PKTQNAVCLMTDAPSEVSEEQLKELHIKVDL

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=593, Percent_Identity=42.1585160202361, Blast_Score=455, Evalue=1e-128,
Organism=Homo sapiens, GI45439306, Length=311, Percent_Identity=27.3311897106109, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI5031815, Length=292, Percent_Identity=26.7123287671233, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI194272210, Length=298, Percent_Identity=26.510067114094, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4758762, Length=283, Percent_Identity=27.208480565371, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI226491502, Length=257, Percent_Identity=22.9571984435798, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788173, Length=587, Percent_Identity=49.9148211243612, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI1790571, Length=320, Percent_Identity=24.6875, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789256, Length=320, Percent_Identity=24.6875, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566633, Length=605, Percent_Identity=36.5289256198347, Blast_Score=357, Evalue=9e-99,
Organism=Caenorhabditis elegans, GI17551876, Length=276, Percent_Identity=28.2608695652174, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994340, Length=355, Percent_Identity=22.5352112676056, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17535927, Length=355, Percent_Identity=22.5352112676056, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=355, Percent_Identity=22.5352112676056, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71984122, Length=304, Percent_Identity=24.3421052631579, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=622, Percent_Identity=35.8520900321543, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6323011, Length=287, Percent_Identity=29.9651567944251, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320242, Length=253, Percent_Identity=24.5059288537549, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321807, Length=285, Percent_Identity=24.2105263157895, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24584738, Length=602, Percent_Identity=37.8737541528239, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=28.4090909090909, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640849, Length=403, Percent_Identity=25.3101736972705, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24640851, Length=403, Percent_Identity=25.3101736972705, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19921528, Length=289, Percent_Identity=25.6055363321799, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67925; Mature: 67794

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEQLNGLKRTHMCGELTVEDVDKYVVVMGWVQRRRDHGGLVFIDLRDRTGIVQVVFSNE
CCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCC
VSSEAFEKVQSVRSEYVLAIEGKVVKRSPENVNPKISTGEIEIYANTLKILSKSETPPFP
CCHHHHHHHHHHHHCEEEEEECEEEECCCCCCCCCEECCEEEEEEHHHHHHHCCCCCCCC
IEDRSNVSEAVRLKYRYLDLRRPSMQKNLMTRFKITKVVRDFLNKNGFIEIETPLLIKST
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECC
PEGARDYLVPSRIYPGKFYALPQSPQIFKQLLMISGFDKYYQIAKCLRDEDLRADRQPEF
CCCCHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCE
TQIDIEMSFVEVEDVLKINEKMIAEIFKETLGIDVPIPFKRLSYQESMERFGTDKPDLRF
EEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
GMELKDLSDIVAQSEFNVFKTALKNNGSVRGINVKGAASMPRRQLDELVEFAKTYGAKGL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCE
LWIQVFEKEVKSPATKFLSEEEMKKILERLEAEAGDLLLIVADKDEIVFDTLAHLRLELG
EEHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHC
KRFNLIDENKYEFVWIVDFPLLEYDEGEKRYVAKHHPFTAPKDEDIELLEKEPLKVRAKA
CCCCCCCCCCEEEEEEEECCEEECCCCCCCEEECCCCCCCCCCCCHHHHCCCCCEEEEEE
YDIVLNGTEIGGGSIRIHDTELQKRMFKVLGFSEEKAWERFGFLMEAFKYGAPPHGGIAY
EEEEEECCEECCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
GLDRLAMIITGSDTIRDVIAFPKTQNAVCLMTDAPSEVSEEQLKELHIKVDL
HHHCEEEEEECCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHEEEEECC
>Mature Secondary Structure 
GEQLNGLKRTHMCGELTVEDVDKYVVVMGWVQRRRDHGGLVFIDLRDRTGIVQVVFSNE
CCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCC
VSSEAFEKVQSVRSEYVLAIEGKVVKRSPENVNPKISTGEIEIYANTLKILSKSETPPFP
CCHHHHHHHHHHHHCEEEEEECEEEECCCCCCCCCEECCEEEEEEHHHHHHHCCCCCCCC
IEDRSNVSEAVRLKYRYLDLRRPSMQKNLMTRFKITKVVRDFLNKNGFIEIETPLLIKST
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECC
PEGARDYLVPSRIYPGKFYALPQSPQIFKQLLMISGFDKYYQIAKCLRDEDLRADRQPEF
CCCCHHCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCE
TQIDIEMSFVEVEDVLKINEKMIAEIFKETLGIDVPIPFKRLSYQESMERFGTDKPDLRF
EEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
GMELKDLSDIVAQSEFNVFKTALKNNGSVRGINVKGAASMPRRQLDELVEFAKTYGAKGL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCE
LWIQVFEKEVKSPATKFLSEEEMKKILERLEAEAGDLLLIVADKDEIVFDTLAHLRLELG
EEHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHC
KRFNLIDENKYEFVWIVDFPLLEYDEGEKRYVAKHHPFTAPKDEDIELLEKEPLKVRAKA
CCCCCCCCCCEEEEEEEECCEEECCCCCCCEEECCCCCCCCCCCCHHHHCCCCCEEEEEE
YDIVLNGTEIGGGSIRIHDTELQKRMFKVLGFSEEKAWERFGFLMEAFKYGAPPHGGIAY
EEEEEECCEECCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
GLDRLAMIITGSDTIRDVIAFPKTQNAVCLMTDAPSEVSEEQLKELHIKVDL
HHHCEEEEEECCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA