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The map label for this gene is cbiL [H]

Identifier: 167038979

GI number: 167038979

Start: 328199

End: 328873

Strand: Direct

Name: cbiL [H]

Synonym: Teth514_0312

Alternate gene names: 167038979

Gene position: 328199-328873 (Clockwise)

Preceding gene: 167038978

Following gene: 167038980

Centisome position: 13.36

GC content: 36.89

Gene sequence:

>675_bases
ATGGCAAAATTATACGGCATAGGAGTAGGACCGGGTGAGGAAAGCCTTATTACTTTAAAAGCTGTAAAAATACTTCAAAA
GGCAGATGTGGTGATAGCGCCCACAAGCAAAGGAGAAGGAAGTATTGCTTATGAGATTGCAAAGCCTTATATAAAAGGCG
ATGTAGTATTGATGGAATTTCCCATGACCTACTCAAAAGAAGACCTTAAAACAAAGTGGGAAGAAAATATTGAAAAAATC
AAAGAGTTGCTTGATGAGGGGAAAGACGTAGCTTTTATAACAATAGGAGACCCCATGATTTACAGTACCTACATATACAT
TTTAAAAGGGATTAAGGATTACGAAGTAGAGACCATTCCTGGAATTACCTCATATAGTGCAGCCGCTTCAAGGTTAAATA
TCCCAGTTGCGGAGGGAAACGAGACTTTTGCAGTGATTCCATCAGGAGATGTGACGGAAATTTCAAAAGCACTTGATATG
TTTGATAACGTGGTATTGATGAAAATTTCGAGAAAATACGATGAAATAGTAAATCTTCTAAAAGAAAAAAGCTTCAAAGG
ATACCTTGTGATAAAGTGCGGCCATCAAGATGAAAAAATATCCTGCGACCTTGATAGATATATAGGGAAAAAGATAGACT
ATTTGTCACTCATTATTGCAAAGAAGGTGAAGTAG

Upstream 100 bases:

>100_bases
ATATGTGTAAATATTTCAGTTTCAAAGGAAGCAGGAAATAAAACGATGATGATAGCTAGAAATCCTGTTTACATAATAAC
GGCGAAAAGAGAGGGATAGA

Downstream 100 bases:

>100_bases
CCGTGATTTATTTTATTGGTGCAGGACCAGGAGACCCTGAACTTATAACATTAAAAGGGATGAAAATAATACAGGCTTGT
GATGTCATCATATACGCAGG

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MAKLYGIGVGPGEESLITLKAVKILQKADVVIAPTSKGEGSIAYEIAKPYIKGDVVLMEFPMTYSKEDLKTKWEENIEKI
KELLDEGKDVAFITIGDPMIYSTYIYILKGIKDYEVETIPGITSYSAAASRLNIPVAEGNETFAVIPSGDVTEISKALDM
FDNVVLMKISRKYDEIVNLLKEKSFKGYLVIKCGHQDEKISCDLDRYIGKKIDYLSLIIAKKVK

Sequences:

>Translated_224_residues
MAKLYGIGVGPGEESLITLKAVKILQKADVVIAPTSKGEGSIAYEIAKPYIKGDVVLMEFPMTYSKEDLKTKWEENIEKI
KELLDEGKDVAFITIGDPMIYSTYIYILKGIKDYEVETIPGITSYSAAASRLNIPVAEGNETFAVIPSGDVTEISKALDM
FDNVVLMKISRKYDEIVNLLKEKSFKGYLVIKCGHQDEKISCDLDRYIGKKIDYLSLIIAKKVK
>Mature_223_residues
AKLYGIGVGPGEESLITLKAVKILQKADVVIAPTSKGEGSIAYEIAKPYIKGDVVLMEFPMTYSKEDLKTKWEENIEKIK
ELLDEGKDVAFITIGDPMIYSTYIYILKGIKDYEVETIPGITSYSAAASRLNIPVAEGNETFAVIPSGDVTEISKALDMF
DNVVLMKISRKYDEIVNLLKEKSFKGYLVIKCGHQDEKISCDLDRYIGKKIDYLSLIIAKKVK

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 24962; Mature: 24831

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYGIGVGPGEESLITLKAVKILQKADVVIAPTSKGEGSIAYEIAKPYIKGDVVLMEF
CCEEEEEECCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCCCEEEEEC
PMTYSKEDLKTKWEENIEKIKELLDEGKDVAFITIGDPMIYSTYIYILKGIKDYEVETIP
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEECC
GITSYSAAASRLNIPVAEGNETFAVIPSGDVTEISKALDMFDNVVLMKISRKYDEIVNLL
CCCCHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHCEEEEHHHHHHHHHHHHH
KEKSFKGYLVIKCGHQDEKISCDLDRYIGKKIDYLSLIIAKKVK
HHCCCCCEEEEEECCCCCCEEECHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKLYGIGVGPGEESLITLKAVKILQKADVVIAPTSKGEGSIAYEIAKPYIKGDVVLMEF
CEEEEEECCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCCCEEEEEC
PMTYSKEDLKTKWEENIEKIKELLDEGKDVAFITIGDPMIYSTYIYILKGIKDYEVETIP
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEECC
GITSYSAAASRLNIPVAEGNETFAVIPSGDVTEISKALDMFDNVVLMKISRKYDEIVNLL
CCCCHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHHHHHHHCEEEEHHHHHHHHHHHHH
KEKSFKGYLVIKCGHQDEKISCDLDRYIGKKIDYLSLIIAKKVK
HHCCCCCEEEEEECCCCCCEEECHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]