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The map label for this gene is csd [H]

Identifier: 167038956

GI number: 167038956

Start: 308815

End: 310062

Strand: Direct

Name: csd [H]

Synonym: Teth514_0289

Alternate gene names: 167038956

Gene position: 308815-310062 (Clockwise)

Preceding gene: 167038955

Following gene: 167038957

Centisome position: 12.57

GC content: 37.66

Gene sequence:

>1248_bases
ATGGAGGAGGATTTTAAAGTGAAATATGTTGATGTAGAAAAGATTAAAAAAGACTTTCCTATATTGAATGTTAAACCTCA
TGGTAAAAAGCTTATTTACCTTGACAATGCTGCCACAACTCAAAAGCCAATTGAAGTCATAAAAGCTATGGATAAATATT
ATGAAGAATTAAACGCCAATGTATACAGAAGCCCACACTATTTAAGCGCTCTTTCCACACAGGCTTATGAAGAGGCAAGA
GAAAGAGTAAAAAAATTTATTAACGCAAAAAGAGAAGAATCCATAATATTTACGAGAAATACTACAGAATCAATAAACTT
TATAGCATATACGTGGGGAATGAAATATATAAACGAAGGGGACGAAATAATACTGACAATAGCCGAGCACCACAGCAATA
TGCTTCCATGGCAAATGGTAGCGGAAGCTAAAAAGGCGAGACTCAAATATGTCCACCTTGATGAGAATTTTAGGCTTTCT
ATGAAAGACTTTAAAGAAAAAATGTCTGACAAAGTAAAATTGGTTGCTGTGCAACACATGTCAAATGTTTTAGGTATAAT
AAATCCTGTGGAGGAGATTACACATATTGCACACAAATACGGCGCAAAAGTGTTAATAGATGGAGCACAAAGTGTACCTC
ATATGCTGATTGATGTACAAAAAATAGGCTGTGACTTTTTTGCTTTTTCTGGTCACAAGATGCTCGGACCTATGGGAATC
GGTGTACTTTATATAAAAGAGGACTTGCTTTCTGATGTGCCTCCTTTTTTAAGAGGTGGAGAGATGATAGACGAAGTCTT
TGAAGACCGTGCAACTTTTGCTCCCCCACCTCTTAAATTTGAAGCAGGTACTCCCAACGTAAAAGGGGCTTGTGTGCTTG
TTTCTGCAATAGATTATATAGAAAAAATTGGGCTTTCCAATATTCATAATCACGAAGGCGAGCTTTTGGAGTATGGCCTT
CAGAAAATGAAAGAATTAGACTTTGTAAAATTGTATGGCCCCAACGATGCGAAGGAAAGGGGAGGCTTAATTTCCTTCAA
TGTAGAAGGTGTCCATCCTCACGACGTTGCTACAATACTAGACGAAGAAGGAATTGCTGTAAGAAGTGGGCACCACTGTT
GTCTGCCTTTAATGAGGTACTTAGGTGTTCCTGCAACTGTAAGAGCAAGCTTTTACCTCTACAACGACTTTGACGATATT
GACGCACTTGTTGAAGGACTAAAAAAAGTCAGGAAGTGGTTCAAATGA

Upstream 100 bases:

>100_bases
AAAATGCACAATATGATAAAATTTCTCTAGGTTATTGTGAAACCTCAAAAGGCTCTAAAAATAATTGGTTTCACAATAAA
TTAACCTAAAAGGGTCATAT

Downstream 100 bases:

>100_bases
GCGATTTAAATCAGCTTTATTCTGAGGTTATAATGGAACATTACGAAAACTCTCCCCATGAAAAAGAACTTAAAGATGCT
ACCCACAAAGAAAGAGGTTA

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MEEDFKVKYVDVEKIKKDFPILNVKPHGKKLIYLDNAATTQKPIEVIKAMDKYYEELNANVYRSPHYLSALSTQAYEEAR
ERVKKFINAKREESIIFTRNTTESINFIAYTWGMKYINEGDEIILTIAEHHSNMLPWQMVAEAKKARLKYVHLDENFRLS
MKDFKEKMSDKVKLVAVQHMSNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMLIDVQKIGCDFFAFSGHKMLGPMGI
GVLYIKEDLLSDVPPFLRGGEMIDEVFEDRATFAPPPLKFEAGTPNVKGACVLVSAIDYIEKIGLSNIHNHEGELLEYGL
QKMKELDFVKLYGPNDAKERGGLISFNVEGVHPHDVATILDEEGIAVRSGHHCCLPLMRYLGVPATVRASFYLYNDFDDI
DALVEGLKKVRKWFK

Sequences:

>Translated_415_residues
MEEDFKVKYVDVEKIKKDFPILNVKPHGKKLIYLDNAATTQKPIEVIKAMDKYYEELNANVYRSPHYLSALSTQAYEEAR
ERVKKFINAKREESIIFTRNTTESINFIAYTWGMKYINEGDEIILTIAEHHSNMLPWQMVAEAKKARLKYVHLDENFRLS
MKDFKEKMSDKVKLVAVQHMSNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMLIDVQKIGCDFFAFSGHKMLGPMGI
GVLYIKEDLLSDVPPFLRGGEMIDEVFEDRATFAPPPLKFEAGTPNVKGACVLVSAIDYIEKIGLSNIHNHEGELLEYGL
QKMKELDFVKLYGPNDAKERGGLISFNVEGVHPHDVATILDEEGIAVRSGHHCCLPLMRYLGVPATVRASFYLYNDFDDI
DALVEGLKKVRKWFK
>Mature_415_residues
MEEDFKVKYVDVEKIKKDFPILNVKPHGKKLIYLDNAATTQKPIEVIKAMDKYYEELNANVYRSPHYLSALSTQAYEEAR
ERVKKFINAKREESIIFTRNTTESINFIAYTWGMKYINEGDEIILTIAEHHSNMLPWQMVAEAKKARLKYVHLDENFRLS
MKDFKEKMSDKVKLVAVQHMSNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMLIDVQKIGCDFFAFSGHKMLGPMGI
GVLYIKEDLLSDVPPFLRGGEMIDEVFEDRATFAPPPLKFEAGTPNVKGACVLVSAIDYIEKIGLSNIHNHEGELLEYGL
QKMKELDFVKLYGPNDAKERGGLISFNVEGVHPHDVATILDEEGIAVRSGHHCCLPLMRYLGVPATVRASFYLYNDFDDI
DALVEGLKKVRKWFK

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=229, Percent_Identity=28.82096069869, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI156713448, Length=246, Percent_Identity=28.4552845528455, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787970, Length=403, Percent_Identity=43.9205955334988, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1789175, Length=398, Percent_Identity=38.1909547738693, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI48994898, Length=231, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193211090, Length=383, Percent_Identity=24.2819843342037, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI25143064, Length=237, Percent_Identity=26.1603375527426, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319831, Length=255, Percent_Identity=32.156862745098, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129463, Length=265, Percent_Identity=28.6792452830189, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 47241; Mature: 47241

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEDFKVKYVDVEKIKKDFPILNVKPHGKKLIYLDNAATTQKPIEVIKAMDKYYEELNAN
CCCCCEEEEEEHHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
VYRSPHYLSALSTQAYEEARERVKKFINAKREESIIFTRNTTESINFIAYTWGMKYINEG
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCHHHHCCC
DEIILTIAEHHSNMLPWQMVAEAKKARLKYVHLDENFRLSMKDFKEKMSDKVKLVAVQHM
CEEEEEEEHHCCCCCCHHHHHHHHHHHEEEEEECCCCEECHHHHHHHHCCCEEEHHHHHH
SNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMLIDVQKIGCDFFAFSGHKMLGPMGI
HHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCEEEECCCCEECCCCC
GVLYIKEDLLSDVPPFLRGGEMIDEVFEDRATFAPPPLKFEAGTPNVKGACVLVSAIDYI
EEEEEEHHHHHCCCHHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
EKIGLSNIHNHEGELLEYGLQKMKELDFVKLYGPNDAKERGGLISFNVEGVHPHDVATIL
HHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHCCCEEEEEECCCCCHHHHHHH
DEEGIAVRSGHHCCLPLMRYLGVPATVRASFYLYNDFDDIDALVEGLKKVRKWFK
CCCCCEEECCCCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEEDFKVKYVDVEKIKKDFPILNVKPHGKKLIYLDNAATTQKPIEVIKAMDKYYEELNAN
CCCCCEEEEEEHHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
VYRSPHYLSALSTQAYEEARERVKKFINAKREESIIFTRNTTESINFIAYTWGMKYINEG
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEECCHHHHCCC
DEIILTIAEHHSNMLPWQMVAEAKKARLKYVHLDENFRLSMKDFKEKMSDKVKLVAVQHM
CEEEEEEEHHCCCCCCHHHHHHHHHHHEEEEEECCCCEECHHHHHHHHCCCEEEHHHHHH
SNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMLIDVQKIGCDFFAFSGHKMLGPMGI
HHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCEEEECCCCEECCCCC
GVLYIKEDLLSDVPPFLRGGEMIDEVFEDRATFAPPPLKFEAGTPNVKGACVLVSAIDYI
EEEEEEHHHHHCCCHHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
EKIGLSNIHNHEGELLEYGLQKMKELDFVKLYGPNDAKERGGLISFNVEGVHPHDVATIL
HHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHCCCEEEEEECCCCCHHHHHHH
DEEGIAVRSGHHCCLPLMRYLGVPATVRASFYLYNDFDDIDALVEGLKKVRKWFK
CCCCCEEECCCCHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]