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The map label for this gene is ziaR [H]

Identifier: 167038914

GI number: 167038914

Start: 261931

End: 262227

Strand: Direct

Name: ziaR [H]

Synonym: Teth514_0245

Alternate gene names: 167038914

Gene position: 261931-262227 (Clockwise)

Preceding gene: 167038913

Following gene: 167038915

Centisome position: 10.66

GC content: 28.28

Gene sequence:

>297_bases
GTGAAAGAAGTGGAAGCTGATGTATATAATAAAGCTGCTGAATACTTTAAAGCATTATCACATCCTACAAGAATAAAGAT
AATAGAGCTTTTAAGCAAAAAAGAAATGTGCGTATGTCAGATGATGGCAGCACTAAATTTAGACCAATCTCATGTATCAA
GGCATTTAATGGTATTAAGAGCAAATAAAATGGTAAAAACAAGAAGAGAAGGGACTATAATTTATTATTCTTTAACAGAT
GAAAATATCATAAACATTATCGAGAAAGTGAAAAATATTTTTCTTGTCAAAAAATAA

Upstream 100 bases:

>100_bases
AGTTTTTTAAAGAATATTTAGTTAAAGTAGCAGAAAGATTAAATTGACAAAAAATTAACTTGACTATATTTGAAAAATCG
AATATAATTTATAGGAAAGG

Downstream 100 bases:

>100_bases
TTTTTTTACTTGCTATATTCGAATATTCGAATATAAAAATATACAAGGAGGTTAATATAAATGATAATTGCTTTTTTAAA
TGCTGGGGAGGAGGTGAAAT

Product: regulatory protein ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MKEVEADVYNKAAEYFKALSHPTRIKIIELLSKKEMCVCQMMAALNLDQSHVSRHLMVLRANKMVKTRREGTIIYYSLTD
ENIINIIEKVKNIFLVKK

Sequences:

>Translated_98_residues
MKEVEADVYNKAAEYFKALSHPTRIKIIELLSKKEMCVCQMMAALNLDQSHVSRHLMVLRANKMVKTRREGTIIYYSLTD
ENIINIIEKVKNIFLVKK
>Mature_98_residues
MKEVEADVYNKAAEYFKALSHPTRIKIIELLSKKEMCVCQMMAALNLDQSHVSRHLMVLRANKMVKTRREGTIIYYSLTD
ENIINIIEKVKNIFLVKK

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11443; Mature: 11443

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVEADVYNKAAEYFKALSHPTRIKIIELLSKKEMCVCQMMAALNLDQSHVSRHLMVLR
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
ANKMVKTRREGTIIYYSLTDENIINIIEKVKNIFLVKK
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEVEADVYNKAAEYFKALSHPTRIKIIELLSKKEMCVCQMMAALNLDQSHVSRHLMVLR
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
ANKMVKTRREGTIIYYSLTDENIINIIEKVKNIFLVKK
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]