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The map label for this gene is php [H]

Identifier: 167038848

GI number: 167038848

Start: 179392

End: 180291

Strand: Direct

Name: php [H]

Synonym: Teth514_0178

Alternate gene names: 167038848

Gene position: 179392-180291 (Clockwise)

Preceding gene: 167038847

Following gene: 167038849

Centisome position: 7.3

GC content: 27.56

Gene sequence:

>900_bases
ATGATTTTAGATAATAATACTGGTTTTAAAGATATAGGTTATACTCTTATACATGAACATTTGACTATTGATTTATCAAG
ACTCAAAGAAGATGATGATGCCAAACTTGATGATGTAGATAGCTTAATTGAAGATTTAAAAGAACTCAAAAAAAGTGGCA
TAGATACTATCGTTGATGTTACAAACATAGGTATGGGTCGAGATATTGAAAGAATCAAGTATATTTCTGATATTTCAAAT
ATGAATGTGATTTTATCTACTGGATTTTATAAAGAACCTTTTTTGCCGGAAATAGTTTATAAGAGTTCTGTTAAAGAATT
GGCTGATATATTTATTGATGAAATTATTAATGGAATCGATGGTACAAATTATAAAGCATCTGTGATAGGCGAGATAGGCA
CAAGTAAAGAAGAAATAAAAGAAGTAGAAAGAAAAATTTTTGAAGCTGCTGCAATTGCACATAATGAAACCGGAGTACCG
ATAATAACTCATACAACGTTAGGGCTTTTAGGATTAGAACAGATTAAAATTTTTAAAAATGTGAAAGTAAATTTAGAAAA
AGTAGTTATAGGGCATGTTGATTTAAACATTGATATGGATTATTATTTAACTTTACTTGATAGTGGATGTTATCTTGCTT
TTGACACAATTGGTAAAACTAATTATCAACCAGATGAGTTAAGAGCAATATCTATAAAGAAACTTATTGACAAAGGATTT
ATTAACAAAATTCTCCTTTCATTGGATATTTCAAGAAAATCTTATCTAAAAAATTATGGTGGTTTTGGCCATTCATATAT
AGTAGAAAAATTTATTCCTCTTTTAAAAAACAATGGGTTAACAGAAGAAGATATAAAGACTATATTATACAGAAATCCAT
TGAACTTGATTGGAGGATAA

Upstream 100 bases:

>100_bases
GCTGGCAGAGATAATTGATAGCAATATTAGCCATCCAAAACTATTTTATGAATATTTTAACACTAAAGAATATGATGATA
TTTTATTTGAGGTGAATTAA

Downstream 100 bases:

>100_bases
AGAATGATTACGTATCCTATTAAACAGATTAGCTTAGAGGAAGCAATTAATTTGCAGTTTAAATTAGTAGATATCATCCA
ATCAGTTTTTCGAGGGCATG

Product: aryldialkylphosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MILDNNTGFKDIGYTLIHEHLTIDLSRLKEDDDAKLDDVDSLIEDLKELKKSGIDTIVDVTNIGMGRDIERIKYISDISN
MNVILSTGFYKEPFLPEIVYKSSVKELADIFIDEIINGIDGTNYKASVIGEIGTSKEEIKEVERKIFEAAAIAHNETGVP
IITHTTLGLLGLEQIKIFKNVKVNLEKVVIGHVDLNIDMDYYLTLLDSGCYLAFDTIGKTNYQPDELRAISIKKLIDKGF
INKILLSLDISRKSYLKNYGGFGHSYIVEKFIPLLKNNGLTEEDIKTILYRNPLNLIGG

Sequences:

>Translated_299_residues
MILDNNTGFKDIGYTLIHEHLTIDLSRLKEDDDAKLDDVDSLIEDLKELKKSGIDTIVDVTNIGMGRDIERIKYISDISN
MNVILSTGFYKEPFLPEIVYKSSVKELADIFIDEIINGIDGTNYKASVIGEIGTSKEEIKEVERKIFEAAAIAHNETGVP
IITHTTLGLLGLEQIKIFKNVKVNLEKVVIGHVDLNIDMDYYLTLLDSGCYLAFDTIGKTNYQPDELRAISIKKLIDKGF
INKILLSLDISRKSYLKNYGGFGHSYIVEKFIPLLKNNGLTEEDIKTILYRNPLNLIGG
>Mature_299_residues
MILDNNTGFKDIGYTLIHEHLTIDLSRLKEDDDAKLDDVDSLIEDLKELKKSGIDTIVDVTNIGMGRDIERIKYISDISN
MNVILSTGFYKEPFLPEIVYKSSVKELADIFIDEIINGIDGTNYKASVIGEIGTSKEEIKEVERKIFEAAAIAHNETGVP
IITHTTLGLLGLEQIKIFKNVKVNLEKVVIGHVDLNIDMDYYLTLLDSGCYLAFDTIGKTNYQPDELRAISIKKLIDKGF
INKILLSLDISRKSYLKNYGGFGHSYIVEKFIPLLKNNGLTEEDIKTILYRNPLNLIGG

Specific function: Its real enzymatic activity is not yet known. It was tested for general esterase, aminopeptidase, sulfatase, phosphatase, carbonic anhydrase, phosphodiesterase, and phosphotriesterase activities with the following substrates:P- nitrophenyl acetate, L-alan

COG id: COG1735

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphotriesterase family [H]

Homologues:

Organism=Homo sapiens, GI20070186, Length=269, Percent_Identity=31.5985130111524, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI47933341, Length=269, Percent_Identity=31.5985130111524, Blast_Score=138, Evalue=5e-33,
Organism=Escherichia coli, GI1789780, Length=285, Percent_Identity=43.1578947368421, Blast_Score=263, Evalue=7e-72,
Organism=Drosophila melanogaster, GI24645325, Length=333, Percent_Identity=24.9249249249249, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017947
- InterPro:   IPR001559 [H]

Pfam domain/function: PF02126 PTE [H]

EC number: NA

Molecular weight: Translated: 33621; Mature: 33621

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01322 PHOSPHOTRIESTERASE_1 ; PS01323 PHOSPHOTRIESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDNNTGFKDIGYTLIHEHLTIDLSRLKEDDDAKLDDVDSLIEDLKELKKSGIDTIVDV
CEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEHH
TNIGMGRDIERIKYISDISNMNVILSTGFYKEPFLPEIVYKSSVKELADIFIDEIINGID
HHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GTNYKASVIGEIGTSKEEIKEVERKIFEAAAIAHNETGVPIITHTTLGLLGLEQIKIFKN
CCCEEEEEHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
VKVNLEKVVIGHVDLNIDMDYYLTLLDSGCYLAFDTIGKTNYQPDELRAISIKKLIDKGF
CCEEEEEEEEEEEEEEECHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
INKILLSLDISRKSYLKNYGGFGHSYIVEKFIPLLKNNGLTEEDIKTILYRNPLNLIGG
HHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MILDNNTGFKDIGYTLIHEHLTIDLSRLKEDDDAKLDDVDSLIEDLKELKKSGIDTIVDV
CEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEHH
TNIGMGRDIERIKYISDISNMNVILSTGFYKEPFLPEIVYKSSVKELADIFIDEIINGID
HHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
GTNYKASVIGEIGTSKEEIKEVERKIFEAAAIAHNETGVPIITHTTLGLLGLEQIKIFKN
CCCEEEEEHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHH
VKVNLEKVVIGHVDLNIDMDYYLTLLDSGCYLAFDTIGKTNYQPDELRAISIKKLIDKGF
CCEEEEEEEEEEEEEEECHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
INKILLSLDISRKSYLKNYGGFGHSYIVEKFIPLLKNNGLTEEDIKTILYRNPLNLIGG
HHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9548740 [H]