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The map label for this gene is oprM [H]

Identifier: 162149524

GI number: 162149524

Start: 3846681

End: 3848216

Strand: Direct

Name: oprM [H]

Synonym: GDI_3762

Alternate gene names: 162149524

Gene position: 3846681-3848216 (Clockwise)

Preceding gene: 162149523

Following gene: 162149526

Centisome position: 97.53

GC content: 70.31

Gene sequence:

>1536_bases
GTGACCATGAGCGCGAGCATGAAGACGAGACGCACATTCCACCGGGCCGGGCTGATGCTGCTGGCCGCCACGATGCTGGC
GGGGTGCACGGTGGGGCCGCGCTACCAGCCGGACCGGATGAAGCTGCCGCCGGGCTTTGCCGAGGACGAGCATGCCGCGA
CGCCGGCGGAAATCGCCCGCACCAATGCCGAGCTGAAGGACTGGTGGCACCGCTTCGGCGACGCCGAGCTGGACCGGCTG
GTCGACCGCGCGATCGCGGGCAATTACGACCTGCAGATCGCCGGCCAGCGCATCCTGGCCGAGCGCGCGCTGCGCGACGT
CCAGGCCTCCGCCTGGTATCCGCAGGTCGATGCCAACACCACCGACGGTGACGCCCGCTATTCCATCAACGTGGACAACT
GGCCGCTGCGCCCGGGCAATCCGGCCAACCGGCCGGGGGCGTCGTACCTGTCCTACGGCGTCAGCGCCAGCTGGCAGATC
GACGTGTTCGGCCGCATCCGCCGCGCGGTCGAGGCCTCGGAACACGCGGTCGAGGAGAATGTCGAGGAACGGCGCGCGGT
GCTGATGACCATGCTGTCGTCGCTGGTCAGCGACTACATGGTGCTGCGCGACACCCAACTGCGGCTGGAGATCTCGAACC
GCAACATCGGGGTGGCGCAGGAAGCCTACGACCTGACGCGGCGCCTGTATCTGGAGGGCGTGGGCAACACGCTGCAGATC
GCCCAGGCGAAGGCCGAGCTGGACGCCCAGCAGGCGGCGCGCGAGCCGCTGCGCACCCATATCGCGCAGATCACCCACGC
CATCGACGTGCTGATGGGCCAGGTGCCCGGCACCACCGAGGCCGAGCTGAAGGTGGCGCAGCCGCTGCCCCAGGTGCCGG
AATTCCCGGCGACGGTGCCCTCGATCGTGCTGGGCAACCGGCCCGACATCCGCCGCGCCGAGCGCGCCTATGCCGAGGCG
ACGGCGCGGATCGGGGTGGCGGTGGCGCAGATGTATCCGAATTTCGCCATTCCGCTGAACTTCAACCCCAACGCGTCGGC
GATGTACCAGGTGTTCGAGGCCGGGGCGCTGAGCTGGCAGTTCTTCATGCTGGCGTCGCTGCCGCTGATGCATGGCGGCA
AGCTGACCGGGCAGATCCGCGCCGCCCAGGCGGCGGCGGAAGCCAGCCGCCTGACCTACCGCCAGACGGTGCTGGGCGCG
TTCCGCGAGGTCGAGGACGCGATGGCGGCGTGGCATGACGACGTGGAGCACACCGAACTGCTGCACCGCGCCGCCGAGGA
CAGCCGGCTGGCCAGCGACCGGGCGCGCAAGCTGTATGCCGCCGGGCTGGTGGGCTTCCTGGAGGTGCTGACCACCGAGC
GCACCGCCCTGGCCGCCGAGAACGCCGAGGCCGTGGCGCGGCTGGAACGCCTGCAGGATGCCATCGACCTCTATACCGCC
ATGGGTGCCGGCTGGCAGGGCGTGGGGGTGACCGCCTCCGCCCTGCCGGTGTCGCTGGAGAAGCAGAACGTCCTGGCGCG
GGCGTTCCAGGATTGA

Upstream 100 bases:

>100_bases
GTGCGCGCGGACACACGCCGGGCGCGGCCCTGCGGGCCGCTCTCGCTCACCAGCCCACGTCTGCGGGCACACATCTTTCA
AACGGACATCGGGCCCGAAC

Downstream 100 bases:

>100_bases
GGGAAGACGTTTTTTTTGAAAAAAGAACCAGAAAACTTTTGATCTGTTCAGGGATTTTCTTGCGTTAGGCTACGGCGCGG
TTGAAGATTGGTGGGACAGG

Product: outer membrane protein oprM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MTMSASMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAELKDWWHRFGDAELDRL
VDRAIAGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGDARYSINVDNWPLRPGNPANRPGASYLSYGVSASWQI
DVFGRIRRAVEASEHAVEENVEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQI
AQAKAELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVAQPLPQVPEFPATVPSIVLGNRPDIRRAERAYAEA
TARIGVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGA
FREVEDAMAAWHDDVEHTELLHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTA
MGAGWQGVGVTASALPVSLEKQNVLARAFQD

Sequences:

>Translated_511_residues
MTMSASMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAELKDWWHRFGDAELDRL
VDRAIAGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGDARYSINVDNWPLRPGNPANRPGASYLSYGVSASWQI
DVFGRIRRAVEASEHAVEENVEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQI
AQAKAELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVAQPLPQVPEFPATVPSIVLGNRPDIRRAERAYAEA
TARIGVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGA
FREVEDAMAAWHDDVEHTELLHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTA
MGAGWQGVGVTASALPVSLEKQNVLARAFQD
>Mature_510_residues
TMSASMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIARTNAELKDWWHRFGDAELDRLV
DRAIAGNYDLQIAGQRILAERALRDVQASAWYPQVDANTTDGDARYSINVDNWPLRPGNPANRPGASYLSYGVSASWQID
VFGRIRRAVEASEHAVEENVEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQIA
QAKAELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVAQPLPQVPEFPATVPSIVLGNRPDIRRAERAYAEAT
ARIGVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQFFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAF
REVEDAMAAWHDDVEHTELLHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTAM
GAGWQGVGVTASALPVSLEKQNVLARAFQD

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=467, Percent_Identity=27.1948608137045, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI2367348, Length=480, Percent_Identity=23.9583333333333, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 56235; Mature: 56104

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSASMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TNAELKDWWHRFGDAELDRLVDRAIAGNYDLQIAGQRILAERALRDVQASAWYPQVDANT
CCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDGDARYSINVDNWPLRPGNPANRPGASYLSYGVSASWQIDVFGRIRRAVEASEHAVEEN
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHH
VEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHH
AQAKAELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVAQPLPQVPEFPATVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCC
SIVLGNRPDIRRAERAYAEATARIGVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQ
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHH
FFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAFREVEDAMAAWHDDVEHTEL
HHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MGAGWQGVGVTASALPVSLEKQNVLARAFQD
HCCCCCCCCCCHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TMSASMKTRRTFHRAGLMLLAATMLAGCTVGPRYQPDRMKLPPGFAEDEHAATPAEIAR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
TNAELKDWWHRFGDAELDRLVDRAIAGNYDLQIAGQRILAERALRDVQASAWYPQVDANT
CCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDGDARYSINVDNWPLRPGNPANRPGASYLSYGVSASWQIDVFGRIRRAVEASEHAVEEN
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHH
VEERRAVLMTMLSSLVSDYMVLRDTQLRLEISNRNIGVAQEAYDLTRRLYLEGVGNTLQI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHH
AQAKAELDAQQAAREPLRTHIAQITHAIDVLMGQVPGTTEAELKVAQPLPQVPEFPATVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCC
SIVLGNRPDIRRAERAYAEATARIGVAVAQMYPNFAIPLNFNPNASAMYQVFEAGALSWQ
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHH
FFMLASLPLMHGGKLTGQIRAAQAAAEASRLTYRQTVLGAFREVEDAMAAWHDDVEHTEL
HHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LHRAAEDSRLASDRARKLYAAGLVGFLEVLTTERTALAAENAEAVARLERLQDAIDLYTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MGAGWQGVGVTASALPVSLEKQNVLARAFQD
HCCCCCCCCCCHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]