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The map label for this gene is ychM [C]

Identifier: 162149397

GI number: 162149397

Start: 3715506

End: 3717191

Strand: Direct

Name: ychM [C]

Synonym: GDI_3635

Alternate gene names: 162149397

Gene position: 3715506-3717191 (Clockwise)

Preceding gene: 162149396

Following gene: 162149398

Centisome position: 94.2

GC content: 71.71

Gene sequence:

>1686_bases
GTGCGGCGGGCGCGCACGGCCCCCCGCGCCCTGGTATCCGGCGTCTGCGCGCCGGGCGGGGCGCGCGACGTGGTGGCCGG
CGTGACCCTGGCCTCGATGAACATTCCGCAGGTGCTGGGCTATGCCGGCATTGCCGCGATGCCGGCCGTGACCGGCCTGT
ATACCGTGCTGCTGCCGCTGGTGGCGTTCGCCCTGCTGGGGTCGTCGCGGCATCTGGTGGTGGCGGCCGATTCCGCCACC
GCCGCCATCTTTTCCAGCGGCCTGGCCGGCATGGCGGCGGCGGGCAGCCCGAAATACGTGGCGCTGGTCGGCACGGTCAC
GTGGCTGGTGGCCGGTTTCCTGTTCGTGGGGCGACTGTTCCGGCTGGGATTCCTGGCGGATTTCTTTTCGCGCACCGTGC
TGGTGGGGTTCCTGGCCGGGGTCGGGGTGCAGGTCGGCATCGCGATGTCGCGCGACATGCTGGGCGTGGCCGCGACCGCC
CATAACCCGGTGCGGCAGTTGCTGCAGGTCGCGGACGGGCTGCCGCACGCCCATCCGCTGACGGTCGGGCTGTCGCTGCT
GGTCGTGGCGGTCATCATGGGGGGGCGGCGGCTGGTGCCGCACGCGCCGCTGGCCATGGTCGCGGTGGTGGGCGGCATCC
TGGCCAGCCGGGTGCTGGACCTAGCGGGGCGGGGGGTGGCCGTCATCGGTCCGATCGCGGGCGGCCTGCCGTCGCTGGGG
CTGCCGGACGTATCGTGGAACGAGATGGTGGCCCTGCTGCCCGTCGCGACCTCGTGCGTGTTCGTCATCATCGCGCAGAG
CGCCGCGACATCGCGGGCTTTCGCCCTGCGCGCTCATGAGGAGGTGGACGAAAACGCCGATATCCTGGGCCTGTGCGCCG
CCAATGCCGCCGCCGCGCTGACGGGCGCCTTCGTCGTGAACGGCAGCCCCACCCAGACGGCCATGGCGGTGCGGGCGGGC
GCGCGCAGCCAGCGGGCGCAGGTGGCATTCGCGCTGGTCACGCTGGTGGTGGTGCTGGTGCTGACCGGGCCGCTGCGCGA
CCTGCCGCGCTGCGTGCTGGCGTCCATCGTCTTCACCGTGGCGGTGGGGATGATCGACTGGCGGGCCATGTGGGCCATCC
GGCGCGAAAGCCCGGGCGAATTCGGCCTGGCCATGGTCACAGCCGCCGCCGTGGTGGGGATCGGGGTGGAACAGGGCATC
TTCCTGGCCATCGCGCTGTCGCTGTTCCGCCATGTCCGGCACAGCTATCGCCCGCACACCATGGTGCTGCGGCAGGACCC
GGTGACCGGCGCGCTGGAGACCGAACCCGTCGCCCCCGGCAGGCAGACGGAACCGGGGCTGGTCGTCTATCGCTTCGGCG
CCGACCTGTTCTACGCCAATTGCAGCCGCTTCACCGACGACGTGCACCTGCTGATCGATCATGCGCCGGCGCCGGTGCGC
TGCTTGATCGTCGATGCCAGCGCGATCACGGACATCGATTTCTCCGCCGCCGGTGCGCTGCGCGACCTGCTGGCGGACTT
GCGCAGGCGGGGCATCGTCGTGCTGTTCGGCCGGGTCAGTTCCTATCTGCGGGCCGACATGCAACGGCACCGCATCCTGT
CGGCCGAAGACCCGAACGCCAACTTCGCCGCCCTGCATCCGGCGCTGGCGGCCGGACGGGCGATCGTGAAGGCAGCCGGG
GCCTGA

Upstream 100 bases:

>100_bases
GCGCCGGCACCGGCAGCGGGGCCTGACCATGGCGCGGCCAGGCATGATTCGGCCAGGCATGATCCGGACAGGCATGATCC
GGGCCGGCATGGCGGCGTCG

Downstream 100 bases:

>100_bases
CCTGTGTCCGTGACAGTGCGTTGCCGGGGGAATCACCTTTGCACGACGTCCTTGCGCCCCCGGCGCGCGATGAACACGTG
CCCTGCACCATCATGGAAAA

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MRRARTAPRALVSGVCAPGGARDVVAGVTLASMNIPQVLGYAGIAAMPAVTGLYTVLLPLVAFALLGSSRHLVVAADSAT
AAIFSSGLAGMAAAGSPKYVALVGTVTWLVAGFLFVGRLFRLGFLADFFSRTVLVGFLAGVGVQVGIAMSRDMLGVAATA
HNPVRQLLQVADGLPHAHPLTVGLSLLVVAVIMGGRRLVPHAPLAMVAVVGGILASRVLDLAGRGVAVIGPIAGGLPSLG
LPDVSWNEMVALLPVATSCVFVIIAQSAATSRAFALRAHEEVDENADILGLCAANAAAALTGAFVVNGSPTQTAMAVRAG
ARSQRAQVAFALVTLVVVLVLTGPLRDLPRCVLASIVFTVAVGMIDWRAMWAIRRESPGEFGLAMVTAAAVVGIGVEQGI
FLAIALSLFRHVRHSYRPHTMVLRQDPVTGALETEPVAPGRQTEPGLVVYRFGADLFYANCSRFTDDVHLLIDHAPAPVR
CLIVDASAITDIDFSAAGALRDLLADLRRRGIVVLFGRVSSYLRADMQRHRILSAEDPNANFAALHPALAAGRAIVKAAG
A

Sequences:

>Translated_561_residues
MRRARTAPRALVSGVCAPGGARDVVAGVTLASMNIPQVLGYAGIAAMPAVTGLYTVLLPLVAFALLGSSRHLVVAADSAT
AAIFSSGLAGMAAAGSPKYVALVGTVTWLVAGFLFVGRLFRLGFLADFFSRTVLVGFLAGVGVQVGIAMSRDMLGVAATA
HNPVRQLLQVADGLPHAHPLTVGLSLLVVAVIMGGRRLVPHAPLAMVAVVGGILASRVLDLAGRGVAVIGPIAGGLPSLG
LPDVSWNEMVALLPVATSCVFVIIAQSAATSRAFALRAHEEVDENADILGLCAANAAAALTGAFVVNGSPTQTAMAVRAG
ARSQRAQVAFALVTLVVVLVLTGPLRDLPRCVLASIVFTVAVGMIDWRAMWAIRRESPGEFGLAMVTAAAVVGIGVEQGI
FLAIALSLFRHVRHSYRPHTMVLRQDPVTGALETEPVAPGRQTEPGLVVYRFGADLFYANCSRFTDDVHLLIDHAPAPVR
CLIVDASAITDIDFSAAGALRDLLADLRRRGIVVLFGRVSSYLRADMQRHRILSAEDPNANFAALHPALAAGRAIVKAAG
A
>Mature_561_residues
MRRARTAPRALVSGVCAPGGARDVVAGVTLASMNIPQVLGYAGIAAMPAVTGLYTVLLPLVAFALLGSSRHLVVAADSAT
AAIFSSGLAGMAAAGSPKYVALVGTVTWLVAGFLFVGRLFRLGFLADFFSRTVLVGFLAGVGVQVGIAMSRDMLGVAATA
HNPVRQLLQVADGLPHAHPLTVGLSLLVVAVIMGGRRLVPHAPLAMVAVVGGILASRVLDLAGRGVAVIGPIAGGLPSLG
LPDVSWNEMVALLPVATSCVFVIIAQSAATSRAFALRAHEEVDENADILGLCAANAAAALTGAFVVNGSPTQTAMAVRAG
ARSQRAQVAFALVTLVVVLVLTGPLRDLPRCVLASIVFTVAVGMIDWRAMWAIRRESPGEFGLAMVTAAAVVGIGVEQGI
FLAIALSLFRHVRHSYRPHTMVLRQDPVTGALETEPVAPGRQTEPGLVVYRFGADLFYANCSRFTDDVHLLIDHAPAPVR
CLIVDASAITDIDFSAAGALRDLLADLRRRGIVVLFGRVSSYLRADMQRHRILSAEDPNANFAALHPALAAGRAIVKAAG
A

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=481, Percent_Identity=23.4927234927235, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI39752683, Length=481, Percent_Identity=23.4927234927235, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI94721257, Length=467, Percent_Identity=25.0535331905782, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI94721253, Length=467, Percent_Identity=25.0535331905782, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI94721259, Length=467, Percent_Identity=25.0535331905782, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI94721255, Length=467, Percent_Identity=25.0535331905782, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI45827802, Length=440, Percent_Identity=23.8636363636364, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI100913030, Length=612, Percent_Identity=21.7320261437909, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI262206105, Length=539, Percent_Identity=22.8200371057514, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI262206075, Length=539, Percent_Identity=22.8200371057514, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI262206069, Length=539, Percent_Identity=22.8200371057514, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI262206063, Length=539, Percent_Identity=22.8200371057514, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI269784651, Length=477, Percent_Identity=21.5932914046122, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI47131207, Length=501, Percent_Identity=25.9481037924152, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI20336272, Length=501, Percent_Identity=25.9481037924152, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI16418413, Length=556, Percent_Identity=21.2230215827338, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI217272867, Length=556, Percent_Identity=21.2230215827338, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4505697, Length=483, Percent_Identity=20.2898550724638, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87081859, Length=429, Percent_Identity=25.1748251748252, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562578, Length=618, Percent_Identity=22.4919093851133, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI86564196, Length=595, Percent_Identity=22.5210084033613, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17566848, Length=572, Percent_Identity=23.6013986013986, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI86565215, Length=551, Percent_Identity=23.956442831216, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17551690, Length=556, Percent_Identity=22.4820143884892, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI86564876, Length=523, Percent_Identity=21.6061185468451, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193203292, Length=503, Percent_Identity=19.0854870775348, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86565213, Length=247, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325260, Length=574, Percent_Identity=21.602787456446, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24649801, Length=539, Percent_Identity=25.6029684601113, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI19922482, Length=518, Percent_Identity=21.6216216216216, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21358229, Length=537, Percent_Identity=22.3463687150838, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI85815873, Length=424, Percent_Identity=22.877358490566, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24663084, Length=529, Percent_Identity=20.9829867674858, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357695, Length=529, Percent_Identity=20.9829867674858, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666186, Length=655, Percent_Identity=22.1374045801527, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 58191; Mature: 58191

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHCHHHHHCCCC
>Mature Secondary Structure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CCHHHHHHHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]