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The map label for this gene is yciK [H]

Identifier: 162149274

GI number: 162149274

Start: 3605831

End: 3606550

Strand: Direct

Name: yciK [H]

Synonym: GDI_3506

Alternate gene names: 162149274

Gene position: 3605831-3606550 (Clockwise)

Preceding gene: 162149273

Following gene: 162149275

Centisome position: 91.42

GC content: 76.11

Gene sequence:

>720_bases
ATGACTCCAGCCACAGTGACCGGGGCCCCGGTGGCACTGGTCACCGGGGCCAGCCGGGGCATCGGCCGCGCCACCGCCCT
GGCCCTGGCCGCGGGCGGGGCGCACTGCATCCTGACCGCCCGCACCCCCGGCGGATTGGAGGAAACCGACGACCTGATCG
AACGCCGCACCGGCCGCCGCGCGACCCTGCTGCCGCTGGACCTGCGCGACGGGGACGCGATCGACACGCTGGGCCCGTCG
ATCGCCGCCCGCTTCGGCCGGCTGGACGTGCTGGTCCATTGCGCCGCCATGCTGGGGGTCCTGACCCCCGTCACCCATAT
GCGCGACGCCGACTGGACCGCCACGCTGGCGGTCAACGCCACGGCCGCCTGGCGGATGATCCGCACCACCGCGCCCCTGC
TGGAACGCGCGCCCGCCGGCCGCGCCGTGTTCCTGACCGACGGGCACGCGACGCACCCCGCCAGCTTCTGGGGCATGATG
GCCGCGTCCAAGGCCGCGATGGAGGCCGTCGTCCTGACCTGGGCCGACGAAATCGCCCCCGGCAGCCCCCTGCGGGTCAA
TCTGTACGACCCCGGCCCGGTGGCCACCCGCCTGCGCGTGCAGGCCATGCCGGCCGCCGACCTGTCCGCCCTGCCCCGCC
CGGACGCGGCGGGCGCGGCCATCGCCGCCCTGTGCCGGCCGGACGAGACCCGGCACGGGCAGCGTATCCGCGCATCCTGA

Upstream 100 bases:

>100_bases
CCGCCGCCGGCCGGTACTGCGACGCCTGCTTCACCGGCGACTACCCGATCCCCCTGGTGGATTACGAAGCCGCAGGCGAC
GACGCGCGTCCCGGCACTCC

Downstream 100 bases:

>100_bases
CGCGACCGCCCCGCCCTGCTATAACACCGGCATGGCCAAGAAAAATTCCCATCCCCAGGCAACCGGCACCCAGGCCACCC
AGGCCCTGACCCGTGCGGGA

Product: short-chain dehydrogenase/reductase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTPATVTGAPVALVTGASRGIGRATALALAAGGAHCILTARTPGGLEETDDLIERRTGRRATLLPLDLRDGDAIDTLGPS
IAARFGRLDVLVHCAAMLGVLTPVTHMRDADWTATLAVNATAAWRMIRTTAPLLERAPAGRAVFLTDGHATHPASFWGMM
AASKAAMEAVVLTWADEIAPGSPLRVNLYDPGPVATRLRVQAMPAADLSALPRPDAAGAAIAALCRPDETRHGQRIRAS

Sequences:

>Translated_239_residues
MTPATVTGAPVALVTGASRGIGRATALALAAGGAHCILTARTPGGLEETDDLIERRTGRRATLLPLDLRDGDAIDTLGPS
IAARFGRLDVLVHCAAMLGVLTPVTHMRDADWTATLAVNATAAWRMIRTTAPLLERAPAGRAVFLTDGHATHPASFWGMM
AASKAAMEAVVLTWADEIAPGSPLRVNLYDPGPVATRLRVQAMPAADLSALPRPDAAGAAIAALCRPDETRHGQRIRAS
>Mature_238_residues
TPATVTGAPVALVTGASRGIGRATALALAAGGAHCILTARTPGGLEETDDLIERRTGRRATLLPLDLRDGDAIDTLGPSI
AARFGRLDVLVHCAAMLGVLTPVTHMRDADWTATLAVNATAAWRMIRTTAPLLERAPAGRAVFLTDGHATHPASFWGMMA
ASKAAMEAVVLTWADEIAPGSPLRVNLYDPGPVATRLRVQAMPAADLSALPRPDAAGAAIAALCRPDETRHGQRIRAS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787526, Length=206, Percent_Identity=34.4660194174757, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787335, Length=191, Percent_Identity=30.3664921465969, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789378, Length=192, Percent_Identity=31.25, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786812, Length=186, Percent_Identity=29.5698924731183, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24872; Mature: 24741

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPATVTGAPVALVTGASRGIGRATALALAAGGAHCILTARTPGGLEETDDLIERRTGRR
CCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCE
ATLLPLDLRDGDAIDTLGPSIAARFGRLDVLVHCAAMLGVLTPVTHMRDADWTATLAVNA
EEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
TAAWRMIRTTAPLLERAPAGRAVFLTDGHATHPASFWGMMAASKAAMEAVVLTWADEIAP
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHCCC
GSPLRVNLYDPGPVATRLRVQAMPAADLSALPRPDAAGAAIAALCRPDETRHGQRIRAS
CCCEEEEEECCCCCCEEEEEEECCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCCEECCC
>Mature Secondary Structure 
TPATVTGAPVALVTGASRGIGRATALALAAGGAHCILTARTPGGLEETDDLIERRTGRR
CCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCE
ATLLPLDLRDGDAIDTLGPSIAARFGRLDVLVHCAAMLGVLTPVTHMRDADWTATLAVNA
EEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
TAAWRMIRTTAPLLERAPAGRAVFLTDGHATHPASFWGMMAASKAAMEAVVLTWADEIAP
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHCCC
GSPLRVNLYDPGPVATRLRVQAMPAADLSALPRPDAAGAAIAALCRPDETRHGQRIRAS
CCCEEEEEECCCCCCEEEEEEECCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]