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The map label for this gene is ccmE

Identifier: 162149210

GI number: 162149210

Start: 3538530

End: 3539051

Strand: Direct

Name: ccmE

Synonym: GDI_3440

Alternate gene names: 162149210

Gene position: 3538530-3539051 (Clockwise)

Preceding gene: 162149209

Following gene: 162149211

Centisome position: 89.72

GC content: 71.65

Gene sequence:

>522_bases
ATGACCCGCAAGAGCCGCCGCCTGTGGCTGGTGGGCGCGTGCCTGCTGGGGCTGGGCACTGCCACCGCCCTGGTGCTGAA
CGCGTTTTCGTCCAACATCGTCTTCTTCATGGCGCCGTCGCAGGTCCGGGCCCATCCGCCGGCCGCCGACCGCACGATCC
GGCTGGGCGGCATGGTGGTGGCGGGGTCGGTGCGGCGCCAGACACAGGGCGACACGCCGATCGCGCTGTTCGACGTGACC
GACGGCCAGGCCGCCGTCACCGTGCGCTATGCCGGCATCCTGCCCGACCTGTTCCGCGAGGGACAGAGCGTGGTCGCCGT
CGGCACCGTGGCGCCGGACGGCGCCTTCCGCGCCAGCGAGGTCCTGGCCAAGCATGACGAGACCTATATGCCCAAGGAAG
TGGCCGAGGCGCTGCGCCGCAGCGGCAAGTGGGACCCGCGCTACGGCAAGGCCCCCGACGCCGCAAGCTGGAACACCATG
ACCGTGGGCGATGCGCGCCACGGCGAGGCCAACCGGTCATGA

Upstream 100 bases:

>100_bases
TGCGCCTGCGTCGGGCGAAGGCCCGCCTGGCAACGGTCGAAGCGAAAGCCCGCCTGGCCACGGTCGAGGCGAAGGCCCGC
CAGGCGACGGGGCGGCAGGC

Downstream 100 bases:

>100_bases
CGCCGGAACTGGGCAATTTCGCGCTGGCGCTGGCCTGCTGCCTGGCCGGCGGGCAGGCGATCCTGCCGCTGGTGGGCGCG
CGGCGGCGCGACCCGCGGCT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MTRKSRRLWLVGACLLGLGTATALVLNAFSSNIVFFMAPSQVRAHPPAADRTIRLGGMVVAGSVRRQTQGDTPIALFDVT
DGQAAVTVRYAGILPDLFREGQSVVAVGTVAPDGAFRASEVLAKHDETYMPKEVAEALRRSGKWDPRYGKAPDAASWNTM
TVGDARHGEANRS

Sequences:

>Translated_173_residues
MTRKSRRLWLVGACLLGLGTATALVLNAFSSNIVFFMAPSQVRAHPPAADRTIRLGGMVVAGSVRRQTQGDTPIALFDVT
DGQAAVTVRYAGILPDLFREGQSVVAVGTVAPDGAFRASEVLAKHDETYMPKEVAEALRRSGKWDPRYGKAPDAASWNTM
TVGDARHGEANRS
>Mature_172_residues
TRKSRRLWLVGACLLGLGTATALVLNAFSSNIVFFMAPSQVRAHPPAADRTIRLGGMVVAGSVRRQTQGDTPIALFDVTD
GQAAVTVRYAGILPDLFREGQSVVAVGTVAPDGAFRASEVLAKHDETYMPKEVAEALRRSGKWDPRYGKAPDAASWNTMT
VGDARHGEANRS

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Also required for indole-3-acetic acid (IAA) biosynthesis

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=143, Percent_Identity=41.958041958042, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_GLUDA (Q69AY8)

Other databases:

- EMBL:   AY456185
- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001603671.1
- RefSeq:   YP_002277279.1
- ProteinModelPortal:   Q69AY8
- SMR:   Q69AY8
- GeneID:   5790861
- GeneID:   6976367
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_2933
- HOGENOM:   HBG296631
- OMA:   HVEFAVH
- ProtClustDB:   PRK13254
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 18539; Mature: 18408

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: BINDING 125-125

Signals:

None

Transmembrane regions:

HASH(0x17a9c228)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKSRRLWLVGACLLGLGTATALVLNAFSSNIVFFMAPSQVRAHPPAADRTIRLGGMVV
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECCEEE
AGSVRRQTQGDTPIALFDVTDGQAAVTVRYAGILPDLFREGQSVVAVGTVAPDGAFRASE
ECCCHHCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHCCCCEEEEEEECCCCCHHHHH
VLAKHDETYMPKEVAEALRRSGKWDPRYGKAPDAASWNTMTVGDARHGEANRS
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCH
>Mature Secondary Structure 
TRKSRRLWLVGACLLGLGTATALVLNAFSSNIVFFMAPSQVRAHPPAADRTIRLGGMVV
CCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECCEEE
AGSVRRQTQGDTPIALFDVTDGQAAVTVRYAGILPDLFREGQSVVAVGTVAPDGAFRASE
ECCCHHCCCCCCCEEEEEECCCCEEEEEEECCCCHHHHHCCCCEEEEEEECCCCCHHHHH
VLAKHDETYMPKEVAEALRRSGKWDPRYGKAPDAASWNTMTVGDARHGEANRS
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA