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The map label for this gene is mdtA [H]

Identifier: 162149135

GI number: 162149135

Start: 3462849

End: 3464156

Strand: Direct

Name: mdtA [H]

Synonym: GDI_3365

Alternate gene names: 162149135

Gene position: 3462849-3464156 (Clockwise)

Preceding gene: 162149131

Following gene: 162149136

Centisome position: 87.8

GC content: 68.65

Gene sequence:

>1308_bases
ATGGACAAACCGACACGCGACCCTTCCGAAGCGCCCGCGCATGAGGCAGCCGGACGGCAGGGCGGGCCCCGGGGCGGATC
ACGTCGCCGTCTGCTTCTCTGGGGAACGGCGCTGGTCGGCGCGGCGGTGATCGCGGCGGCGTTCCTGCGGCCGCATACCC
ACACCACCGGCGGCAGCGGCCGCCACGGCCACCAGGCGGTCGGGGACGCGCAGCCCGTCGCCGTGGCGACGGTCCATCCC
GGCGACATGCCGATCGAACTGACCGAACTGGGCACCGTGGTGCCGATCACGAACGTCACGGTACAGCCCCGCGTCGACGG
CTACCTGATGCAGGTCCTGTTCACCGAGGGCCAGCACGTGAAGAAGGGCGACCTGCTGGCGCTGATCGACACCCGGCCGT
ACGAGGTGGCGCTGGCGCAGTACCAGGGCCAGCTGGCCTCGGACATCGCGCAGCTCCAGCAGGCGCGGGTGGACAACGAC
CGCTACCAGCGCCTGGTCCGCCAGAACAGTATCGCGACCCAGACCGCCCAGGACCAGCAATACAAGGTCGCGCAGCTCGA
AGGCACCGTGAAGGTCGACCAGGCCATGGTCGACAACGAAAAACTGCAGCTCGTGTACTGCCACGTCATCGCCCCCGTGG
ACGGGCGCGTCGGCATCCGCCAGGTGGACATGGGCAACTACGTGACCGCCGGGCAGACCAACGGGCTGGTCATCCTGACG
CAGATGCAGCCGATTTCGGTCATCTTCACCCTGCCCGAAACCGAACTGGGCGCGGTGGCCGAGCGGCTGCGCACCGGCAT
CGCCCTGCCGGTCGCGGCCTGGGACAGCACCAACACGCGCAAGATCGCCGACGGCACGGTCAGCGTGCTGGACAGCCAGA
TCGACACCTCGACCGGCACGGTGCGCCTGCGCTCGATCTTCACAAACCAGGACGAAACCCTGTTCCCGAACCAGTTCGTC
AACGCCCACCTGCTGGTCAACACCCAGCATAACGTGCTGCTGGTGCCGACCAACGCGGTCCAGACCGGGCCCAACGGACC
GTTCACCTATGTCGTCAAGCCCGACAAAACGGTCGAGGTCCGCGACATCAAGACCGGCGCCACCCACGGCGACGTGGTGG
TCGCGGCCTCGGGCCTGAAGGATGGCGACGTGGTCGTGACCGACGGCACCGACCGCCTGCATGCGGGGTCGAAGGTCACC
ATCCCGGCGGCGGCCGACGCCAGGACGGGTACCGACACCAAGACGGGCGCCGATACCAAGGCGGGCACGGACAACGGGTC
CCGTTCGGGCGCCCAGGGTCGGCAATGA

Upstream 100 bases:

>100_bases
TTAACGTCAATTCCCGACGCAGATGCTAACACTGCCCCCGAAGCCGCTCACGCGGCACGACGCGCCCGACGCCAACTGGA
TTGAGGAAGACCCGACGACC

Downstream 100 bases:

>100_bases
CCCCCTCGGCCATGAACCCGGCCAATCCCCCGATCCGTCTTCCCCTGCCGGAGAGCCGTGCGTGAATCCCTCCCGCCTGT
TCATCGAACGCCCGGTCGCG

Product: multidrug resistance protein mdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MDKPTRDPSEAPAHEAAGRQGGPRGGSRRRLLLWGTALVGAAVIAAAFLRPHTHTTGGSGRHGHQAVGDAQPVAVATVHP
GDMPIELTELGTVVPITNVTVQPRVDGYLMQVLFTEGQHVKKGDLLALIDTRPYEVALAQYQGQLASDIAQLQQARVDND
RYQRLVRQNSIATQTAQDQQYKVAQLEGTVKVDQAMVDNEKLQLVYCHVIAPVDGRVGIRQVDMGNYVTAGQTNGLVILT
QMQPISVIFTLPETELGAVAERLRTGIALPVAAWDSTNTRKIADGTVSVLDSQIDTSTGTVRLRSIFTNQDETLFPNQFV
NAHLLVNTQHNVLLVPTNAVQTGPNGPFTYVVKPDKTVEVRDIKTGATHGDVVVAASGLKDGDVVVTDGTDRLHAGSKVT
IPAAADARTGTDTKTGADTKAGTDNGSRSGAQGRQ

Sequences:

>Translated_435_residues
MDKPTRDPSEAPAHEAAGRQGGPRGGSRRRLLLWGTALVGAAVIAAAFLRPHTHTTGGSGRHGHQAVGDAQPVAVATVHP
GDMPIELTELGTVVPITNVTVQPRVDGYLMQVLFTEGQHVKKGDLLALIDTRPYEVALAQYQGQLASDIAQLQQARVDND
RYQRLVRQNSIATQTAQDQQYKVAQLEGTVKVDQAMVDNEKLQLVYCHVIAPVDGRVGIRQVDMGNYVTAGQTNGLVILT
QMQPISVIFTLPETELGAVAERLRTGIALPVAAWDSTNTRKIADGTVSVLDSQIDTSTGTVRLRSIFTNQDETLFPNQFV
NAHLLVNTQHNVLLVPTNAVQTGPNGPFTYVVKPDKTVEVRDIKTGATHGDVVVAASGLKDGDVVVTDGTDRLHAGSKVT
IPAAADARTGTDTKTGADTKAGTDNGSRSGAQGRQ
>Mature_435_residues
MDKPTRDPSEAPAHEAAGRQGGPRGGSRRRLLLWGTALVGAAVIAAAFLRPHTHTTGGSGRHGHQAVGDAQPVAVATVHP
GDMPIELTELGTVVPITNVTVQPRVDGYLMQVLFTEGQHVKKGDLLALIDTRPYEVALAQYQGQLASDIAQLQQARVDND
RYQRLVRQNSIATQTAQDQQYKVAQLEGTVKVDQAMVDNEKLQLVYCHVIAPVDGRVGIRQVDMGNYVTAGQTNGLVILT
QMQPISVIFTLPETELGAVAERLRTGIALPVAAWDSTNTRKIADGTVSVLDSQIDTSTGTVRLRSIFTNQDETLFPNQFV
NAHLLVNTQHNVLLVPTNAVQTGPNGPFTYVVKPDKTVEVRDIKTGATHGDVVVAASGLKDGDVVVTDGTDRLHAGSKVT
IPAAADARTGTDTKTGADTKAGTDNGSRSGAQGRQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=370, Percent_Identity=44.5945945945946, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1789929, Length=396, Percent_Identity=29.040404040404, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786668, Length=353, Percent_Identity=30.8781869688385, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789665, Length=383, Percent_Identity=30.0261096605744, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081951, Length=163, Percent_Identity=28.8343558282209, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46295; Mature: 46295

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPTRDPSEAPAHEAAGRQGGPRGGSRRRLLLWGTALVGAAVIAAAFLRPHTHTTGGSG
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCC
RHGHQAVGDAQPVAVATVHPGDMPIELTELGTVVPITNVTVQPRVDGYLMQVLFTEGQHV
CCCCCCCCCCCCEEEEEECCCCCCEEHHHCCCEEEEECEEECCCCCCEEEEEECCCCCCC
KKGDLLALIDTRPYEVALAQYQGQLASDIAQLQQARVDNDRYQRLVRQNSIATQTAQDQQ
CCCCEEEEEECCCCEEHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCCCCC
YKVAQLEGTVKVDQAMVDNEKLQLVYCHVIAPVDGRVGIRQVDMGNYVTAGQTNGLVILT
EEEEEECCCEEEHHHHCCCCCEEEEEEEEEECCCCCCCEEEECCCCEEECCCCCCEEEEE
QMQPISVIFTLPETELGAVAERLRTGIALPVAAWDSTNTRKIADGTVSVLDSQIDTSTGT
ECCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCEEECCCHHHHHHHHCCCCCCE
VRLRSIFTNQDETLFPNQFVNAHLLVNTQHNVLLVPTNAVQTGPNGPFTYVVKPDKTVEV
EEEEEEECCCCCEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCCEEEE
RDIKTGATHGDVVVAASGLKDGDVVVTDGTDRLHAGSKVTIPAAADARTGTDTKTGADTK
EEEECCCCCCCEEEEECCCCCCCEEEECCCCHHCCCCEEEEECCCCCCCCCCCCCCCCCC
AGTDNGSRSGAQGRQ
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MDKPTRDPSEAPAHEAAGRQGGPRGGSRRRLLLWGTALVGAAVIAAAFLRPHTHTTGGSG
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCC
RHGHQAVGDAQPVAVATVHPGDMPIELTELGTVVPITNVTVQPRVDGYLMQVLFTEGQHV
CCCCCCCCCCCCEEEEEECCCCCCEEHHHCCCEEEEECEEECCCCCCEEEEEECCCCCCC
KKGDLLALIDTRPYEVALAQYQGQLASDIAQLQQARVDNDRYQRLVRQNSIATQTAQDQQ
CCCCEEEEEECCCCEEHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCCCCC
YKVAQLEGTVKVDQAMVDNEKLQLVYCHVIAPVDGRVGIRQVDMGNYVTAGQTNGLVILT
EEEEEECCCEEEHHHHCCCCCEEEEEEEEEECCCCCCCEEEECCCCEEECCCCCCEEEEE
QMQPISVIFTLPETELGAVAERLRTGIALPVAAWDSTNTRKIADGTVSVLDSQIDTSTGT
ECCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCEEECCCHHHHHHHHCCCCCCE
VRLRSIFTNQDETLFPNQFVNAHLLVNTQHNVLLVPTNAVQTGPNGPFTYVVKPDKTVEV
EEEEEEECCCCCEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCCEEEE
RDIKTGATHGDVVVAASGLKDGDVVVTDGTDRLHAGSKVTIPAAADARTGTDTKTGADTK
EEEECCCCCCCEEEEECCCCCCCEEEECCCCHHCCCCEEEEECCCCCCCCCCCCCCCCCC
AGTDNGSRSGAQGRQ
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA