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The map label for this gene is cocE [H]

Identifier: 162148919

GI number: 162148919

Start: 3238791

End: 3240803

Strand: Direct

Name: cocE [H]

Synonym: GDI_3149

Alternate gene names: 162148919

Gene position: 3238791-3240803 (Clockwise)

Preceding gene: 162148918

Following gene: 162148920

Centisome position: 82.12

GC content: 67.71

Gene sequence:

>2013_bases
TTGACACTTTCTACACGTCGTCGCCCGGGCGGGACGATCACCTTCCTGACCGCCCTGACCCTGGCCAGCAGCATCGGTGC
CATCGGCCTGGGCAACCCGGGCCACGCCGCCCCCAAGCCGTCCCGGACCGCCACCCCCGCGTCCACGCAGCAGGGTGCCT
CGGTGCTGACCGTCCAGACCGGGAGCGACATCCCCGCCCATGTCACCTTTCCGACCGACGGGCGCGACTACGTCAAGCGC
GACGTCATGATCCCGATGCGCGACGGGGTGAAGCTGCACACCGTCATCGTGGTGCCCCGCAACGCGCATGACGCGCCGAT
CCTGCTGACGCGCACGCCCTATCACGCGTCGCAGCGGCTGAACCGGGTCGAGGATTCGCCGTCCATGCGCGCGCTGCTGC
CGCAGGGCGACGATGTGTTCGTCGAATCGGGCTATATCCGCGTCTTCCAGGACATTCGGGGCAAGTACGGGTCGGAAGGC
GATTACGTGATGACGCGCCCGGTGCGCGGGCCGCTGAACCCCACCCGCACCGACGAGGTCACCGACGCGTGGGACACGAT
CGACTGGCTGGTCAAGAACCTGCCGGAATCGAACGGCCGCGTGGGCATGCTGGGCTCGTCCTATGAGGGGTTCACCGTGG
TCATGGCGCTGCTGAACCCGCATCCGGCGCTGAAGGTCGCGGCCCCGGAAAGCCCGATGGTCGACGGCTGGATGGGCGAT
GACTGGTACCATTACGGCGCCTTCCGCCAGGGCGGGCTGGATTATTTCACCGAGCAGATGACCGTCCGTGGCGAGGGCAA
CCCGATTCCCCGCGTGGACCGCGACGATTACACGAACTTCCTGCGGGCCGGATCGGCCGGGCAGTTCGCCACCGCCGCCG
GTCTGGACCAGTTCCCGTGGTGGCAGCGCATGCTGGCCCACCCGGACTACGATGCCTTCTGGCAGAACCAGGCCCTGGAC
AAGCTGATCACCCGCCACCCGCTGACGGTGCCCACCCTGTGGGAACAGGGCCTGTGGGACCAGGAAGACATGTGGGGCGC
GATCCATTCCTGGCAGGCGCTGAAGAAGACCAGCCCCAGCGTGCCGAACATCCTGGTCATGGGCCCGTGGCGGCACAGCC
AGGTCAATTATGACGGATCGGAACTGGGCCCGCTGCATTGGGACGGCGACACCGCGCACCAGTTCCGGCGCGACGTGCTG
CTGCCGTTCTTCAACCAGTACCTGCGCCCCGGCGCGCCGGCGGCGAACCTGCCGGAAGCCATCATCTACAATTCCGGCGA
GAACCACTGGGACCGCTTCCCGCGCTGGCCCCTGGCCTGCGATGGCAAGGGCTGCGCCCATCCGATGAAGCCGCTGTTCC
TGCAGGCGGGATACGGCCTGTCGTTCGATCATCCGGCGGCGGACGGGCAGGATTCCTATGTGTCCGATCCCGCGCATCCG
GTGCCCTTCCTGCAGCGCCCGTTCAATTTCGCGACCGACGGCGCACGCTGGAAGACGTGGCTGGTGCAGGACCAGCGCCA
GGCGGAAAGCCGCCCGGACGTCCTGACCTATGAAACCCCGGTCCTGACGCAGTCGGTCCGCGTCAGCGGCGTGCCGGTGG
CGGATCTGTTCGCGGCGACCAGCGGCACCGATTCGGACTGGGTGGTGAAGCTGATCGACGTGCAGCCGGCCACCAACGGC
GACCGGCCGGAGATGGGCGGATACGAGCTGGCGGTGTCGATGGACATCTTCCGCGGCCGCTATCGCGAGGGCTTCGATCA
TTCGGTGGCCACGGTGCCGAACCAGGTGGCGCGCTATCGCTTCACGCTGCCGGCGGTCAACCACGTGTTCCAGCCGGGGC
ACCGGATCATGGTGCAGATCCAGTCCTCGCTGTTCCCACTCTATGACCGCAACCCGCAGACCTTCGTGCCCAACGTGCTG
CGCGCCACGCCGCATGACTTCGTCGCCGCGACGCAGTCGGTCCATCGCGGCGGCGACCAGTCCACGGCGATCTGGCTGCC
GGTCGTCCCGTAA

Upstream 100 bases:

>100_bases
CCGGCGAGGCCCGGTTGCCTGATCCGTTCGGTTGCGACATGGTCATGCCAACGAAACACCTTGTCCTCCGCTGTGGCGGA
GATCAGCAGGAGCGTATGGT

Downstream 100 bases:

>100_bases
CCGCCCGGCGCACAACGGCGTCACGGAGTGGCCGGAGGGGGAGTCATGCGTCTATGATGGCCGCATGAACTCCCCCTCCC
CCGTTTCGGCCGCGATCCTC

Product: dipeptidyl-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MTLSTRRRPGGTITFLTALTLASSIGAIGLGNPGHAAPKPSRTATPASTQQGASVLTVQTGSDIPAHVTFPTDGRDYVKR
DVMIPMRDGVKLHTVIVVPRNAHDAPILLTRTPYHASQRLNRVEDSPSMRALLPQGDDVFVESGYIRVFQDIRGKYGSEG
DYVMTRPVRGPLNPTRTDEVTDAWDTIDWLVKNLPESNGRVGMLGSSYEGFTVVMALLNPHPALKVAAPESPMVDGWMGD
DWYHYGAFRQGGLDYFTEQMTVRGEGNPIPRVDRDDYTNFLRAGSAGQFATAAGLDQFPWWQRMLAHPDYDAFWQNQALD
KLITRHPLTVPTLWEQGLWDQEDMWGAIHSWQALKKTSPSVPNILVMGPWRHSQVNYDGSELGPLHWDGDTAHQFRRDVL
LPFFNQYLRPGAPAANLPEAIIYNSGENHWDRFPRWPLACDGKGCAHPMKPLFLQAGYGLSFDHPAADGQDSYVSDPAHP
VPFLQRPFNFATDGARWKTWLVQDQRQAESRPDVLTYETPVLTQSVRVSGVPVADLFAATSGTDSDWVVKLIDVQPATNG
DRPEMGGYELAVSMDIFRGRYREGFDHSVATVPNQVARYRFTLPAVNHVFQPGHRIMVQIQSSLFPLYDRNPQTFVPNVL
RATPHDFVAATQSVHRGGDQSTAIWLPVVP

Sequences:

>Translated_670_residues
MTLSTRRRPGGTITFLTALTLASSIGAIGLGNPGHAAPKPSRTATPASTQQGASVLTVQTGSDIPAHVTFPTDGRDYVKR
DVMIPMRDGVKLHTVIVVPRNAHDAPILLTRTPYHASQRLNRVEDSPSMRALLPQGDDVFVESGYIRVFQDIRGKYGSEG
DYVMTRPVRGPLNPTRTDEVTDAWDTIDWLVKNLPESNGRVGMLGSSYEGFTVVMALLNPHPALKVAAPESPMVDGWMGD
DWYHYGAFRQGGLDYFTEQMTVRGEGNPIPRVDRDDYTNFLRAGSAGQFATAAGLDQFPWWQRMLAHPDYDAFWQNQALD
KLITRHPLTVPTLWEQGLWDQEDMWGAIHSWQALKKTSPSVPNILVMGPWRHSQVNYDGSELGPLHWDGDTAHQFRRDVL
LPFFNQYLRPGAPAANLPEAIIYNSGENHWDRFPRWPLACDGKGCAHPMKPLFLQAGYGLSFDHPAADGQDSYVSDPAHP
VPFLQRPFNFATDGARWKTWLVQDQRQAESRPDVLTYETPVLTQSVRVSGVPVADLFAATSGTDSDWVVKLIDVQPATNG
DRPEMGGYELAVSMDIFRGRYREGFDHSVATVPNQVARYRFTLPAVNHVFQPGHRIMVQIQSSLFPLYDRNPQTFVPNVL
RATPHDFVAATQSVHRGGDQSTAIWLPVVP
>Mature_669_residues
TLSTRRRPGGTITFLTALTLASSIGAIGLGNPGHAAPKPSRTATPASTQQGASVLTVQTGSDIPAHVTFPTDGRDYVKRD
VMIPMRDGVKLHTVIVVPRNAHDAPILLTRTPYHASQRLNRVEDSPSMRALLPQGDDVFVESGYIRVFQDIRGKYGSEGD
YVMTRPVRGPLNPTRTDEVTDAWDTIDWLVKNLPESNGRVGMLGSSYEGFTVVMALLNPHPALKVAAPESPMVDGWMGDD
WYHYGAFRQGGLDYFTEQMTVRGEGNPIPRVDRDDYTNFLRAGSAGQFATAAGLDQFPWWQRMLAHPDYDAFWQNQALDK
LITRHPLTVPTLWEQGLWDQEDMWGAIHSWQALKKTSPSVPNILVMGPWRHSQVNYDGSELGPLHWDGDTAHQFRRDVLL
PFFNQYLRPGAPAANLPEAIIYNSGENHWDRFPRWPLACDGKGCAHPMKPLFLQAGYGLSFDHPAADGQDSYVSDPAHPV
PFLQRPFNFATDGARWKTWLVQDQRQAESRPDVLTYETPVLTQSVRVSGVPVADLFAATSGTDSDWVVKLIDVQPATNGD
RPEMGGYELAVSMDIFRGRYREGFDHSVATVPNQVARYRFTLPAVNHVFQPGHRIMVQIQSSLFPLYDRNPQTFVPNVLR
ATPHDFVAATQSVHRGGDQSTAIWLPVVP

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 74607; Mature: 74475

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTRRRPGGTITFLTALTLASSIGAIGLGNPGHAAPKPSRTATPASTQQGASVLTVQT
CCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
GSDIPAHVTFPTDGRDYVKRDVMIPMRDGVKLHTVIVVPRNAHDAPILLTRTPYHASQRL
CCCCCEEEECCCCCHHHHHHCCEEECCCCCEEEEEEEEECCCCCCCEEEEECCCHHHHHH
NRVEDSPSMRALLPQGDDVFVESGYIRVFQDIRGKYGSEGDYVMTRPVRGPLNPTRTDEV
HHHCCCCCCEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCH
TDAWDTIDWLVKNLPESNGRVGMLGSSYEGFTVVMALLNPHPALKVAAPESPMVDGWMGD
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHEEHHCCCCCEEEECCCCCCCCCCCCC
DWYHYGAFRQGGLDYFTEQMTVRGEGNPIPRVDRDDYTNFLRAGSAGQFATAAGLDQFPW
CCEECCCCCCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCCCHH
WQRMLAHPDYDAFWQNQALDKLITRHPLTVPTLWEQGLWDQEDMWGAIHSWQALKKTSPS
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
VPNILVMGPWRHSQVNYDGSELGPLHWDGDTAHQFRRDVLLPFFNQYLRPGAPAANLPEA
CCEEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IIYNSGENHWDRFPRWPLACDGKGCAHPMKPLFLQAGYGLSFDHPAADGQDSYVSDPAHP
EEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
VPFLQRPFNFATDGARWKTWLVQDQRQAESRPDVLTYETPVLTQSVRVSGVPVADLFAAT
CCHHHCCCCCCCCCCCEEEEEECCHHHHCCCCCEEEECCCCCCCCEEECCCCHHHHHHHC
SGTDSDWVVKLIDVQPATNGDRPEMGGYELAVSMDIFRGRYREGFDHSVATVPNQVARYR
CCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHCCHHHHHEE
FTLPAVNHVFQPGHRIMVQIQSSLFPLYDRNPQTFVPNVLRATPHDFVAATQSVHRGGDQ
EECHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCC
STAIWLPVVP
CCEEEEECCC
>Mature Secondary Structure 
TLSTRRRPGGTITFLTALTLASSIGAIGLGNPGHAAPKPSRTATPASTQQGASVLTVQT
CCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
GSDIPAHVTFPTDGRDYVKRDVMIPMRDGVKLHTVIVVPRNAHDAPILLTRTPYHASQRL
CCCCCEEEECCCCCHHHHHHCCEEECCCCCEEEEEEEEECCCCCCCEEEEECCCHHHHHH
NRVEDSPSMRALLPQGDDVFVESGYIRVFQDIRGKYGSEGDYVMTRPVRGPLNPTRTDEV
HHHCCCCCCEEECCCCCEEEEECCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCH
TDAWDTIDWLVKNLPESNGRVGMLGSSYEGFTVVMALLNPHPALKVAAPESPMVDGWMGD
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHEEHHCCCCCEEEECCCCCCCCCCCCC
DWYHYGAFRQGGLDYFTEQMTVRGEGNPIPRVDRDDYTNFLRAGSAGQFATAAGLDQFPW
CCEECCCCCCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHCCCCCCHH
WQRMLAHPDYDAFWQNQALDKLITRHPLTVPTLWEQGLWDQEDMWGAIHSWQALKKTSPS
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
VPNILVMGPWRHSQVNYDGSELGPLHWDGDTAHQFRRDVLLPFFNQYLRPGAPAANLPEA
CCEEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IIYNSGENHWDRFPRWPLACDGKGCAHPMKPLFLQAGYGLSFDHPAADGQDSYVSDPAHP
EEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
VPFLQRPFNFATDGARWKTWLVQDQRQAESRPDVLTYETPVLTQSVRVSGVPVADLFAAT
CCHHHCCCCCCCCCCCEEEEEECCHHHHCCCCCEEEECCCCCCCCEEECCCCHHHHHHHC
SGTDSDWVVKLIDVQPATNGDRPEMGGYELAVSMDIFRGRYREGFDHSVATVPNQVARYR
CCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHCCHHHHHEE
FTLPAVNHVFQPGHRIMVQIQSSLFPLYDRNPQTFVPNVLRATPHDFVAATQSVHRGGDQ
EECHHHHHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCC
STAIWLPVVP
CCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]