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The map label for this gene is nrdJ [H]

Identifier: 162146732

GI number: 162146732

Start: 924246

End: 925928

Strand: Reverse

Name: nrdJ [H]

Synonym: GDI_0910

Alternate gene names: 162146732

Gene position: 925928-924246 (Counterclockwise)

Preceding gene: 162146740

Following gene: 162146731

Centisome position: 23.48

GC content: 73.86

Gene sequence:

>1683_bases
ATGGACCTACCATATCCGGCTTTCGCCCCGTCACGAAGCGAGCCTAGACTGATGGTCATGACAGCCCGAAGCCATTGGAA
CGGCGTACGCATGCGTACCACGCAGGCCGCCGCGGACCCGGACGACGCCCTCCGCGCCGTCACCCTGCCCGTCGATTGGG
ACGACGAGGCCGCGGCTGCGCTGGCGCGGATGGCGCCGGGGCGCGGCACGGTCCGCCTGGCGGCCGAGGCCGCGCGCTGG
GTGGACGACCTGGCGGTCGGTCCCCTTGCCGCCCAGGCGCGGTCGCTGTCATGCCTGCTGATGATGCGCCAGGCCGCCCC
GACGGAGTCGCTGTGGACCGGCCAGCATGACCGGCGCCCCGGCTTCATCGTCAACCTGGCGGGGTTCGTGCAGCCCGGGT
CCGGCTTCCTGGCCGACGATTTCGTGGCCGCGCTGCGCCTGATGTGCCTGGTGCTGCGCGACGCCGCCGAGCGCAAGGCC
GCGCTGCGCAACGGTGAACTGCCGTTCCTCGACCTTCCGCCTCCGGCGCCTCCGACCGGCGGCAAGGCCAAGGCCCGCAC
GGCGGGGGCCAGGGCGGGGACGAAAACCGGGGCCGGTCCCGATCCGCGCCAGTCGGACCTGCCCCAGCCGCCCCTGGTCG
CGGGCAACCTGCTGCTGACCAACCTCGATGCCTGCCTGGCCGCGCTGGGCCTGGATTATGACAGCGAGACGGCACGTGAC
GTGGCGTGCAGCCTGGCGTCGCTGGCGACGTCGGTCGCGCATGCCGGCGGCGGGGTCGATTCCCTGCTGCTGCCGCCCGC
GCGCAGCGTCGTGCCGGGCCTGGCGGAGGCCGCCCGGGCCGTCTGGCGCGATGCCGCGGTGGAAACCGACACCATCCTGC
CCCGCATCGAGACCGGATTTTCCGCCCCCGGCCCGATCGACGCCCTGCTGGGGGTCGAGGCCTGCGGGCTGGCCCCGATC
TTCTCGCCCCTGCGGCCGGACGGGCGCCTGGCCGCCAGCACCCTGGCACGGCTGGCCTGGCGCGGCCTGACGCCCGAATC
CGCCTTCGCCGCCGCCCTGGCGGGCGAGACCGTGCTGCGGCTGCCCGACACCCAGGCCCATCAGGCCATGCATCGCGCCG
TGGCCGGGTTCGTCGACCGCATGCCCGCCCGGCCCGACGCCACGGCCGTGCCGCTGCGCGCGCGCCTGGCGCTGGAACGC
GGGGCACGGCGCAACCTGCCGGCACGCCATGGCGGCTTCACGCAGAAGGCCAGTGTCGGCGGCCACCGGCTGTTCCTGCG
CACCGGCGAATACGAGGACGGCACGCTGGGCGAGGTCGCGATCACCCCGGCGCGCGAGGGCCCGATGGCGCGCGGCCTGA
TGGACGCGCTGGGCCAGGCGGTCAGCATCGGCCTGCAATACGGCGCGCCGCTGGACGCCTATGTGGATGCGTTCGCCTAT
ACGCGTTTCGGCCCCGCCGGCACGGTGGAGGGGGATTCGGTTGCATCCTATGCCACCTCTCTGCTGGATTATGCGTTCCG
GGCCTTGTCGGATGCCTATCTGGGCCACAGACTGCCCGACGCGCCGCATCAGGACGACATCGCCGATGCCCCGTCGCCGA
TGCTGCCGCTGGATTTTCCCGCCGCACCCGATGGCCGCGCTTCGGGGGGGCGGCGCGGCGGCCGGTTGCGGCTGGTGGGC
TGA

Upstream 100 bases:

>100_bases
GGGTCCATCCCGCGCCGACGGCGCGCATCCTCACATGTCCGGGATCGCGGAACCCGCGAGTTATCCCCCATATCCACAAT
ATACAGTGGTCTGTATAGGT

Downstream 100 bases:

>100_bases
TCGGCCGCCCTGCGGCCGGACAAACGCCCGCGACCATTTGAACAGGAGTCTCCCATGACGGACAGCACACCCGAAGCCCG
CCTGGACCGGCACGGCATCG

Product: vitamin B12-dependent ribonucleotide reductase

Products: NA

Alternate protein names: Ribonucleoside-diphosphate reductase nrdJ [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MDLPYPAFAPSRSEPRLMVMTARSHWNGVRMRTTQAAADPDDALRAVTLPVDWDDEAAAALARMAPGRGTVRLAAEAARW
VDDLAVGPLAAQARSLSCLLMMRQAAPTESLWTGQHDRRPGFIVNLAGFVQPGSGFLADDFVAALRLMCLVLRDAAERKA
ALRNGELPFLDLPPPAPPTGGKAKARTAGARAGTKTGAGPDPRQSDLPQPPLVAGNLLLTNLDACLAALGLDYDSETARD
VACSLASLATSVAHAGGGVDSLLLPPARSVVPGLAEAARAVWRDAAVETDTILPRIETGFSAPGPIDALLGVEACGLAPI
FSPLRPDGRLAASTLARLAWRGLTPESAFAAALAGETVLRLPDTQAHQAMHRAVAGFVDRMPARPDATAVPLRARLALER
GARRNLPARHGGFTQKASVGGHRLFLRTGEYEDGTLGEVAITPAREGPMARGLMDALGQAVSIGLQYGAPLDAYVDAFAY
TRFGPAGTVEGDSVASYATSLLDYAFRALSDAYLGHRLPDAPHQDDIADAPSPMLPLDFPAAPDGRASGGRRGGRLRLVG

Sequences:

>Translated_560_residues
MDLPYPAFAPSRSEPRLMVMTARSHWNGVRMRTTQAAADPDDALRAVTLPVDWDDEAAAALARMAPGRGTVRLAAEAARW
VDDLAVGPLAAQARSLSCLLMMRQAAPTESLWTGQHDRRPGFIVNLAGFVQPGSGFLADDFVAALRLMCLVLRDAAERKA
ALRNGELPFLDLPPPAPPTGGKAKARTAGARAGTKTGAGPDPRQSDLPQPPLVAGNLLLTNLDACLAALGLDYDSETARD
VACSLASLATSVAHAGGGVDSLLLPPARSVVPGLAEAARAVWRDAAVETDTILPRIETGFSAPGPIDALLGVEACGLAPI
FSPLRPDGRLAASTLARLAWRGLTPESAFAAALAGETVLRLPDTQAHQAMHRAVAGFVDRMPARPDATAVPLRARLALER
GARRNLPARHGGFTQKASVGGHRLFLRTGEYEDGTLGEVAITPAREGPMARGLMDALGQAVSIGLQYGAPLDAYVDAFAY
TRFGPAGTVEGDSVASYATSLLDYAFRALSDAYLGHRLPDAPHQDDIADAPSPMLPLDFPAAPDGRASGGRRGGRLRLVG
>Mature_560_residues
MDLPYPAFAPSRSEPRLMVMTARSHWNGVRMRTTQAAADPDDALRAVTLPVDWDDEAAAALARMAPGRGTVRLAAEAARW
VDDLAVGPLAAQARSLSCLLMMRQAAPTESLWTGQHDRRPGFIVNLAGFVQPGSGFLADDFVAALRLMCLVLRDAAERKA
ALRNGELPFLDLPPPAPPTGGKAKARTAGARAGTKTGAGPDPRQSDLPQPPLVAGNLLLTNLDACLAALGLDYDSETARD
VACSLASLATSVAHAGGGVDSLLLPPARSVVPGLAEAARAVWRDAAVETDTILPRIETGFSAPGPIDALLGVEACGLAPI
FSPLRPDGRLAASTLARLAWRGLTPESAFAAALAGETVLRLPDTQAHQAMHRAVAGFVDRMPARPDATAVPLRARLALER
GARRNLPARHGGFTQKASVGGHRLFLRTGEYEDGTLGEVAITPAREGPMARGLMDALGQAVSIGLQYGAPLDAYVDAFAY
TRFGPAGTVEGDSVASYATSLLDYAFRALSDAYLGHRLPDAPHQDDIADAPSPMLPLDFPAAPDGRASGGRRGGRLRLVG

Specific function: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen [H]

COG id: COG0209

COG function: function code F; Ribonucleotide reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase class-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002876
- InterPro:   IPR017856
- InterPro:   IPR013344
- InterPro:   IPR000788
- InterPro:   IPR013678 [H]

Pfam domain/function: PF08471 Ribonuc_red_2_N; PF02867 Ribonuc_red_lgC [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 58617; Mature: 58617

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPYPAFAPSRSEPRLMVMTARSHWNGVRMRTTQAAADPDDALRAVTLPVDWDDEAAAA
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHH
LARMAPGRGTVRLAAEAARWVDDLAVGPLAAQARSLSCLLMMRQAAPTESLWTGQHDRRP
HHHHCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
GFIVNLAGFVQPGSGFLADDFVAALRLMCLVLRDAAERKAALRNGELPFLDLPPPAPPTG
CEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
GKAKARTAGARAGTKTGAGPDPRQSDLPQPPLVAGNLLLTNLDACLAALGLDYDSETARD
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
VACSLASLATSVAHAGGGVDSLLLPPARSVVPGLAEAARAVWRDAAVETDTILPRIETGF
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCC
SAPGPIDALLGVEACGLAPIFSPLRPDGRLAASTLARLAWRGLTPESAFAAALAGETVLR
CCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEE
LPDTQAHQAMHRAVAGFVDRMPARPDATAVPLRARLALERGARRNLPARHGGFTQKASVG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHCCCCCCCCCCCCCCCCC
GHRLFLRTGEYEDGTLGEVAITPAREGPMARGLMDALGQAVSIGLQYGAPLDAYVDAFAY
CEEEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TRFGPAGTVEGDSVASYATSLLDYAFRALSDAYLGHRLPDAPHQDDIADAPSPMLPLDFP
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AAPDGRASGGRRGGRLRLVG
CCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MDLPYPAFAPSRSEPRLMVMTARSHWNGVRMRTTQAAADPDDALRAVTLPVDWDDEAAAA
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHH
LARMAPGRGTVRLAAEAARWVDDLAVGPLAAQARSLSCLLMMRQAAPTESLWTGQHDRRP
HHHHCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
GFIVNLAGFVQPGSGFLADDFVAALRLMCLVLRDAAERKAALRNGELPFLDLPPPAPPTG
CEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
GKAKARTAGARAGTKTGAGPDPRQSDLPQPPLVAGNLLLTNLDACLAALGLDYDSETARD
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
VACSLASLATSVAHAGGGVDSLLLPPARSVVPGLAEAARAVWRDAAVETDTILPRIETGF
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCC
SAPGPIDALLGVEACGLAPIFSPLRPDGRLAASTLARLAWRGLTPESAFAAALAGETVLR
CCCCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEE
LPDTQAHQAMHRAVAGFVDRMPARPDATAVPLRARLALERGARRNLPARHGGFTQKASVG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCHHCCCCCCCCCCCCCCCCC
GHRLFLRTGEYEDGTLGEVAITPAREGPMARGLMDALGQAVSIGLQYGAPLDAYVDAFAY
CEEEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TRFGPAGTVEGDSVASYATSLLDYAFRALSDAYLGHRLPDAPHQDDIADAPSPMLPLDFP
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
AAPDGRASGGRRGGRLRLVG
CCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]