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The map label for this gene is adh [H]

Identifier: 162146724

GI number: 162146724

Start: 917549

End: 918619

Strand: Reverse

Name: adh [H]

Synonym: GDI_0902

Alternate gene names: 162146724

Gene position: 918619-917549 (Counterclockwise)

Preceding gene: 162146725

Following gene: 162146723

Centisome position: 23.29

GC content: 70.31

Gene sequence:

>1071_bases
GTGATCCAGATCATGGTACGGGGTGTGCCGATATGGTGCAGTTCCTGCGCCGATCCTGCCCACCGCGCCGGAGACCCCGC
GATGATGCACGCGATGCGATTGAATGCCCCGCATACCGACCTGGAATGGGTGGAACTGCCCGACCGCCTGCCCGGCCCCG
GCGAGATCCGGGTGCGCGTCGGGGCCTGCGGCGTGTGCCGCACCGACCTGCACGTGGTGGATGGCGACCTGCCCTTTCCC
GGCCATCCGGTCATTCCGGGGCACGAGATCGTGGGCCGGATCGAGGCGCTGGGCGAGGGTGTGCAGGACCTGAAGATCGG
CCAGCGGGTCGGCGTGCCGTGGCTGGGCCATACCTGCGGCATCTGCCGCTACTGCCACAGCGGGCATGAAAACCTGTGCG
ACCATCCGCTTTTCACCGGCTACACCCGCGACGGCGGCTATGCCACCGCCGCCATCGCCGATGCCCGCTATGCGTTTCCG
CTGGGCGAGGAAGGCAGCGACGTGGACCTGGCCCCCCTGCTGTGCGCGGGGCTGATCGGCTGGCGGTCGCTGGTGATGGC
GGGCGAGGACGCGAAGACGGTGGGGCTGTACGGCTTCGGCGCCGCCGCGCACATCATCGCCCAGGTGGCGCTGTGGCAGG
GCCGCACCGTCTATGGCTTCACCCGCCCGGGCGACCGCCCGACGCAGGATTTCGCCCGGTCGCTGGGCGCGACCTGGGCC
GGCGGATCGGACGAGGCGCCGCCGGAGAAGCTGGACGCCGCCATCATCTTCGCCCCCGTGGGCGCGCTGGTTCCGGCGGC
CCTGCGCGCGGTGCGCAAGGGCGGCCGCGTGGTCTGTGCCGGTATCCACATGAGCGACATCCCCAGCTTCCCCTACGATT
TGTTTTGGGAGGAACGGCAACTGGTTTCGGTCGCCAACCTGACACGGCAGGACGGTATCGATTTCCTCTCGCTGGCGCCC
AGGATCGGCGTCCGCACCAAGACGACGCGCTACGACCTGCGCGATGCCAACCGCGCGCTGGCCGACCTGCGGGCCGGACG
GTTCGAGGGCGCGGCGGTGCTGGTGCCCTGA

Upstream 100 bases:

>100_bases
ACGCATGCGCGTTTCCGGCTAAATTCTTAACGGCGTCCCCGCAACGCGCATACTGCCTGCCGGGCGGACCCGGTCACGAT
CCGGTTATGGCGGGGCCGGA

Downstream 100 bases:

>100_bases
GCGGCGCGGGCGGGCAAAGGGCGCGGATTGAGGCATTTTACCGGCCATTCCGCTTTATCGCTGGCCTTTTCGGCGGGGGT
TCTTTATGGAGCGCCCTTTC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MIQIMVRGVPIWCSSCADPAHRAGDPAMMHAMRLNAPHTDLEWVELPDRLPGPGEIRVRVGACGVCRTDLHVVDGDLPFP
GHPVIPGHEIVGRIEALGEGVQDLKIGQRVGVPWLGHTCGICRYCHSGHENLCDHPLFTGYTRDGGYATAAIADARYAFP
LGEEGSDVDLAPLLCAGLIGWRSLVMAGEDAKTVGLYGFGAAAHIIAQVALWQGRTVYGFTRPGDRPTQDFARSLGATWA
GGSDEAPPEKLDAAIIFAPVGALVPAALRAVRKGGRVVCAGIHMSDIPSFPYDLFWEERQLVSVANLTRQDGIDFLSLAP
RIGVRTKTTRYDLRDANRALADLRAGRFEGAAVLVP

Sequences:

>Translated_356_residues
MIQIMVRGVPIWCSSCADPAHRAGDPAMMHAMRLNAPHTDLEWVELPDRLPGPGEIRVRVGACGVCRTDLHVVDGDLPFP
GHPVIPGHEIVGRIEALGEGVQDLKIGQRVGVPWLGHTCGICRYCHSGHENLCDHPLFTGYTRDGGYATAAIADARYAFP
LGEEGSDVDLAPLLCAGLIGWRSLVMAGEDAKTVGLYGFGAAAHIIAQVALWQGRTVYGFTRPGDRPTQDFARSLGATWA
GGSDEAPPEKLDAAIIFAPVGALVPAALRAVRKGGRVVCAGIHMSDIPSFPYDLFWEERQLVSVANLTRQDGIDFLSLAP
RIGVRTKTTRYDLRDANRALADLRAGRFEGAAVLVP
>Mature_356_residues
MIQIMVRGVPIWCSSCADPAHRAGDPAMMHAMRLNAPHTDLEWVELPDRLPGPGEIRVRVGACGVCRTDLHVVDGDLPFP
GHPVIPGHEIVGRIEALGEGVQDLKIGQRVGVPWLGHTCGICRYCHSGHENLCDHPLFTGYTRDGGYATAAIADARYAFP
LGEEGSDVDLAPLLCAGLIGWRSLVMAGEDAKTVGLYGFGAAAHIIAQVALWQGRTVYGFTRPGDRPTQDFARSLGATWA
GGSDEAPPEKLDAAIIFAPVGALVPAALRAVRKGGRVVCAGIHMSDIPSFPYDLFWEERQLVSVANLTRQDGIDFLSLAP
RIGVRTKTTRYDLRDANRALADLRAGRFEGAAVLVP

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=101, Percent_Identity=41.5841584158416, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI34577061, Length=83, Percent_Identity=44.578313253012, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4501929, Length=101, Percent_Identity=40.5940594059406, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI71743840, Length=90, Percent_Identity=40, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI262073058, Length=90, Percent_Identity=40, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI71565154, Length=85, Percent_Identity=40, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87081918, Length=340, Percent_Identity=30.5882352941176, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082401, Length=136, Percent_Identity=36.7647058823529, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786518, Length=154, Percent_Identity=35.7142857142857, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787863, Length=225, Percent_Identity=31.1111111111111, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI226510992, Length=123, Percent_Identity=34.9593495934959, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790045, Length=262, Percent_Identity=26.7175572519084, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788075, Length=168, Percent_Identity=25.5952380952381, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=275, Percent_Identity=28.7272727272727, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562582, Length=160, Percent_Identity=30, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=160, Percent_Identity=29.375, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562878, Length=165, Percent_Identity=28.4848484848485, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=259, Percent_Identity=25.8687258687259, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324486, Length=275, Percent_Identity=31.2727272727273, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323961, Length=163, Percent_Identity=36.8098159509202, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323729, Length=146, Percent_Identity=39.7260273972603, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319621, Length=352, Percent_Identity=28.6931818181818, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323980, Length=142, Percent_Identity=35.2112676056338, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319949, Length=197, Percent_Identity=33.502538071066, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17737895, Length=89, Percent_Identity=38.2022471910112, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR014187
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 38209; Mature: 38209

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIMVRGVPIWCSSCADPAHRAGDPAMMHAMRLNAPHTDLEWVELPDRLPGPGEIRVRV
CEEEEEECCCEEECCCCCHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEEE
GACGVCRTDLHVVDGDLPFPGHPVIPGHEIVGRIEALGEGVQDLKIGQRVGVPWLGHTCG
ECCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHH
ICRYCHSGHENLCDHPLFTGYTRDGGYATAAIADARYAFPLGEEGSDVDLAPLLCAGLIG
HHHHHHCCCCCCCCCCCCCCEECCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHH
WRSLVMAGEDAKTVGLYGFGAAAHIIAQVALWQGRTVYGFTRPGDRPTQDFARSLGATWA
HHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCC
GGSDEAPPEKLDAAIIFAPVGALVPAALRAVRKGGRVVCAGIHMSDIPSFPYDLFWEERQ
CCCCCCCHHHHCEEEEEECHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCHHHHHHHHH
LVSVANLTRQDGIDFLSLAPRIGVRTKTTRYDLRDANRALADLRAGRFEGAAVLVP
HHHHHHHHHHCCCCHHHHCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MIQIMVRGVPIWCSSCADPAHRAGDPAMMHAMRLNAPHTDLEWVELPDRLPGPGEIRVRV
CEEEEEECCCEEECCCCCHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEEE
GACGVCRTDLHVVDGDLPFPGHPVIPGHEIVGRIEALGEGVQDLKIGQRVGVPWLGHTCG
ECCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHH
ICRYCHSGHENLCDHPLFTGYTRDGGYATAAIADARYAFPLGEEGSDVDLAPLLCAGLIG
HHHHHHCCCCCCCCCCCCCCEECCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHH
WRSLVMAGEDAKTVGLYGFGAAAHIIAQVALWQGRTVYGFTRPGDRPTQDFARSLGATWA
HHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCC
GGSDEAPPEKLDAAIIFAPVGALVPAALRAVRKGGRVVCAGIHMSDIPSFPYDLFWEERQ
CCCCCCCHHHHCEEEEEECHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCHHHHHHHHH
LVSVANLTRQDGIDFLSLAPRIGVRTKTTRYDLRDANRALADLRAGRFEGAAVLVP
HHHHHHHHHHCCCCHHHHCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]