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The map label for this gene is pyrH [H]

Identifier: 161870972

GI number: 161870972

Start: 2103651

End: 2104370

Strand: Direct

Name: pyrH [H]

Synonym: NMCC_2067

Alternate gene names: 161870972

Gene position: 2103651-2104370 (Clockwise)

Preceding gene: 161870971

Following gene: 161870973

Centisome position: 97.69

GC content: 52.78

Gene sequence:

>720_bases
ATGACACAGCAAATCAAATACAAACGCGTATTACTGAAACTCTCCGGCGAATCCCTGATGGGTTCCGATCCGTTCGGCAT
CAATCACGACACCATCGTCCAAACCGTCGGCGAAATTGCCGAAGTCGTTAAAATGGGCGTACAGGTCGGCATCGTCGTGG
GCGGCGGCAATATTTTCCGGGGCGTATCCGCCCAAGCAGGCAGCATGGACCGCGCCACTGCCGATTACATGGGTATGATG
GCGACCGTGATGAACGCCTTGGCACTCAAAGACGCATTTGAAACTTTAGGCATCAAAGCGCGCGTACAATCCGCACTGTC
TATGCAGCAAATCGCTGAAACTTACGCCCGTCCTAAAGCCATCCAATATTTGGAAGAAGGCAAAGTCGTGATTTTTGCCG
CCGGTACCGGTAACCCGTTCTTCACGACCGACACTGCCGCCGCATTGCGCGGTGCGGAAATGAACTGCGACGTGATGCTT
AAAGCCACCAACGTCGACGGCGTGTACACCGCAGACCCCAAAAAAGACTCATCCGCCACGCGCTACGAAACCATTACTTT
TGACGAAGCCTTGTTGAAAAACCTCAAAGTGATGGATGCCACCGCTTTCGCCCTCTGCCGCGAACGCAAGCTCAATATTG
TAGTATTCGGCATTGCTAAAGAAGGCTCGCTCAAACGTGTAGTAACCGGTGAAAACGAAGGTACGCTGGTTCACTGCTGA

Upstream 100 bases:

>100_bases
AAACAATAATAAACCGACACACCCTATCATTAATATTCCGACCGTTTGAAATTCAGACGACCCAACTCCGACCGACGACA
TTCAAGAAAGCAAGGTATCC

Downstream 100 bases:

>100_bases
TTGACCATAGTGTCGGCAGATATAGTCGCATATGGGCTTCAGACAGCCATTTATTATATGGAGATTATAGTGGATTAAAT
TTAAACCAGTACGGCGTTGC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVKMGVQVGIVVGGGNIFRGVSAQAGSMDRATADYMGMM
ATVMNALALKDAFETLGIKARVQSALSMQQIAETYARPKAIQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVML
KATNVDGVYTADPKKDSSATRYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGIAKEGSLKRVVTGENEGTLVHC

Sequences:

>Translated_239_residues
MTQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVKMGVQVGIVVGGGNIFRGVSAQAGSMDRATADYMGMM
ATVMNALALKDAFETLGIKARVQSALSMQQIAETYARPKAIQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVML
KATNVDGVYTADPKKDSSATRYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGIAKEGSLKRVVTGENEGTLVHC
>Mature_238_residues
TQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVKMGVQVGIVVGGGNIFRGVSAQAGSMDRATADYMGMMA
TVMNALALKDAFETLGIKARVQSALSMQQIAETYARPKAIQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVMLK
ATNVDGVYTADPKKDSSATRYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGIAKEGSLKRVVTGENEGTLVHC

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=53.6796536796537, Blast_Score=260, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25675; Mature: 25544

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVKMGVQVGIVVGGGNIFR
CCCCHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEC
GVSAQAGSMDRATADYMGMMATVMNALALKDAFETLGIKARVQSALSMQQIAETYARPKA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHH
IQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVMLKATNVDGVYTADPKKDSSAT
HHHHHCCCEEEEEECCCCCCEECCHHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCCCC
RYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGIAKEGSLKRVVTGENEGTLVHC
EEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCEEEC
>Mature Secondary Structure 
TQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVKMGVQVGIVVGGGNIFR
CCCHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEC
GVSAQAGSMDRATADYMGMMATVMNALALKDAFETLGIKARVQSALSMQQIAETYARPKA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHH
IQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVMLKATNVDGVYTADPKKDSSAT
HHHHHCCCEEEEEECCCCCCEECCHHHHHCCCCCCCEEEEEEECCCCEEECCCCCCCCCC
RYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGIAKEGSLKRVVTGENEGTLVHC
EEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA