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The map label for this gene is lpcA [H]

Identifier: 161870960

GI number: 161870960

Start: 2094004

End: 2094597

Strand: Direct

Name: lpcA [H]

Synonym: NMCC_2055

Alternate gene names: 161870960

Gene position: 2094004-2094597 (Clockwise)

Preceding gene: 161870959

Following gene: 161870961

Centisome position: 97.24

GC content: 58.42

Gene sequence:

>594_bases
ATGACGACATTACAAGAACGCGTTGCCGCCCATTTTGCCGAAAGCATCCGTGCCAAACAGGAAGCCGAAAAAGTACTGGT
CGAGCCGACCGTACAGGCTGCCGAGCTGATGCTGCAATGCCTGATGAACGACGGCAAGATTCTGGCGTGCGGCAACGGCG
GTTCGGCCGCCGATGCCCAGCACTTCGCCGCCGAAATGACCGGACGCTTTGAAAAAGAGCGCATGGAACTCGCCGCCGTC
GCCCTGACCACAGACACCTCCGCGCTGACCGCCATCGGTAACGACTACGGCTTCAACCACGTCTTCAGCAAACAGGTACG
CGCCCTCGGACGTGCAGGCGACGTCTTGGTCGGCATTTCCACTTCCGGCAATTCCGCCAACGTCATCGAAGCCGTCAAAG
CCGCACACGAACGCGATATGCACGTCATCGCCCTGACCGGCCGCGACGGCGGCAAAATCGCCGCCATGCTCAAAGACACC
GACGTTTTACTCAACGTTCCCTATCCTCGAACTGCCCGTATTCAGGAAAACCACATCCTGCTGATACACGCCATGTGCGA
CTGTATCGACTCCGTACTGCTGGAAGGAATGTAA

Upstream 100 bases:

>100_bases
CAACAGAACAGGCTGACAAACGTACCGTGCCGCCTCGATGCGGTACTGATTGAAGGAAACCGCCCGCCCGAGTGGATACA
GAATATTACAGGTTGACGAT

Downstream 100 bases:

>100_bases
CCCTTTTCAGACGGCATGGCGCAAAGCAATGCCGTCTGAAACGCCCAAGAAAGGAAGCACCCGATGAAACCCAAACCGCA
CACCGTCCGCACCCTGATTG

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTTLQERVAAHFAESIRAKQEAEKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEMTGRFEKERMELAAV
ALTTDTSALTAIGNDYGFNHVFSKQVRALGRAGDVLVGISTSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAMLKDT
DVLLNVPYPRTARIQENHILLIHAMCDCIDSVLLEGM

Sequences:

>Translated_197_residues
MTTLQERVAAHFAESIRAKQEAEKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEMTGRFEKERMELAAV
ALTTDTSALTAIGNDYGFNHVFSKQVRALGRAGDVLVGISTSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAMLKDT
DVLLNVPYPRTARIQENHILLIHAMCDCIDSVLLEGM
>Mature_196_residues
TTLQERVAAHFAESIRAKQEAEKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEMTGRFEKERMELAAVA
LTTDTSALTAIGNDYGFNHVFSKQVRALGRAGDVLVGISTSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAMLKDTD
VLLNVPYPRTARIQENHILLIHAMCDCIDSVLLEGM

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=191, Percent_Identity=52.3560209424084, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1786416, Length=165, Percent_Identity=49.6969696969697, Blast_Score=157, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21104; Mature: 20973

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLQERVAAHFAESIRAKQEAEKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHH
HFAAEMTGRFEKERMELAAVALTTDTSALTAIGNDYGFNHVFSKQVRALGRAGDVLVGIS
HHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
TSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAMLKDTDVLLNVPYPRTARIQENHIL
CCCCCHHHHHHHHHHHHCCEEEEEEECCCCCEEEEEEECCEEEEECCCCCCCEECCCCEE
LIHAMCDCIDSVLLEGM
EHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTLQERVAAHFAESIRAKQEAEKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHH
HFAAEMTGRFEKERMELAAVALTTDTSALTAIGNDYGFNHVFSKQVRALGRAGDVLVGIS
HHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEE
TSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAMLKDTDVLLNVPYPRTARIQENHIL
CCCCCHHHHHHHHHHHHCCEEEEEEECCCCCEEEEEEECCEEEEECCCCCCCEECCCCEE
LIHAMCDCIDSVLLEGM
EHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA