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The map label for this gene is katA [H]

Identifier: 161870846

GI number: 161870846

Start: 1979152

End: 1980666

Strand: Direct

Name: katA [H]

Synonym: NMCC_1929

Alternate gene names: 161870846

Gene position: 1979152-1980666 (Clockwise)

Preceding gene: 161870845

Following gene: 161870847

Centisome position: 91.91

GC content: 57.56

Gene sequence:

>1515_bases
ATGACTACCTCCAAATGCCCCGTAACCCATCTGACCATGAACAACGGCGCGCCTGTTGCCGACAATCAAAACAGCCTGAC
CGCCGGTCCGCGCGGCCCCCTGCTGGCGCAGGATTTGTGGCTGAATGAAAAACTCGCCGACTTCGTGCGCGAAGTCATTC
CCGAACGCCGTATGCACGCCAAAGGTTCGGGCGCGTTCGGTACGTTTACCGTAACACACGACATCACCAAATACACCCGC
GCCAAAATCTTCAGCGAAGTCGGCAAAAAAACTGAAATGTTCGCCCGTTTCACCACCGTGGCAGGCGAACGCGGCGCAGC
CGATGCAGAACGCGACATCCGCGGTTTTGCATTGAAATTTTATACCGAAGAAGGCAACTGGGATGTGGTCGGCAACAACA
CGCCCGTGTTCTTCCTGCGCGACCCGCGTAAGTTCCCCGACCTGAATAAAGCCGTCAAACGCGATCCGCGCACCAATATG
CGCTCTGCCACAAACAACTGGGACTTCTGGACGCTGCTGCCCGAAGCCCTGCACCAAGTTACCATCGTGATGAGCGACCG
CGGCATCCCAGCCGGCTACCGCCATATGCACGGCTTCGGTTCGCATACCTACAGCTTCTGGAACGAAGCAGGCGAGCGTT
TTTGGGTGAAATTCCATTTCCGCACCCAACAAGGCATTAAAAACCTGACCAACGAAGAAGCCGCCAAAATCATCGCCGAC
GACCGCGAAAGCCATCAGCGCGACCTGTACGAAGCCATCGAACGCGGCGAGTTTCCGAAATGGACGATGTACATCCAAGT
CATGCCTGAAGCAGACGCGGAAAAAGTACCTTATCATCCGTTTGACTTGACCAAAGTTTGGCCGAAAAAAGACTATCCGC
TGATTGAAGTGGGCGAATTCGAGTTGAACCGCAATCCCGAAAACTTCTTCGCCGATGTGGAACAATCCGCCTTCGCACCG
AGCAACCTCGTTCCCGGTGTCGGCGCCAGCCCAGATAAAATGTTGCAGGCGCGTTTGTTCAATTACGCCGACGCGCAACG
CTACCGCTTGGGCGTGAACTTCCGCCAAATCCCTGTCAACCGTCCGCGTTGCCCTGTTCACAGCAACCAGCGCGACGGAC
AAGGCAGAGCCGACGGCAACTACGGCAGCCTGCCGCACTACGAACCCAACAGCTTCGGACAATGGCAGCAGCAGCCCGAC
TTCGCCGAACCGCCTTTGAAAATCAACGGCGACGCGGCACACTGGGACTACCGCCAAGATGATGACGACTACTTCAGCCA
ACCGCGCGCCCTGTTCAACCTGATGAACGACGCGCAGAAACAGGCATTGTTCGGCAACACCGCCGCCGCAATGGGCGACG
CGCCCGACTTCATCAAATACCGCCATATCCGCAACTGCTACCGTTGCGATCCGGCATACGGTGAAGGCGTGGCAAAAGCC
CTCGGACTGACTGTCGAAGACGCACAAGCCGCCCGCGCGACCGACCCCGCACTCGGCCAGCCCGGTTTGCTGTAA

Upstream 100 bases:

>100_bases
TTATTGCAATCAAGAAACCGGTTACGAATACGCTTTCCGCCAAATCGTACTGTAAGCCGTTTACCCCCATTTGACCAACC
TGAGAAAAGGAACAAGAGCG

Downstream 100 bases:

>100_bases
GGGGGCATTATGTGGATGGAAATTGAAGAAATCCTGTCCCGCGCCGTCCGCTACCGGAAATAACCGGGCATAAAAATGCC
GTCTGAAACGTCGTTTGACC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MTTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTHDITKYTR
AKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNM
RSATNNWDFWTLLPEALHQVTIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKFHFRTQQGIKNLTNEEAAKIIAD
DRESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKVPYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQSAFAP
SNLVPGVGASPDKMLQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRADGNYGSLPHYEPNSFGQWQQQPD
FAEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFGNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGVAKA
LGLTVEDAQAARATDPALGQPGLL

Sequences:

>Translated_504_residues
MTTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTHDITKYTR
AKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNM
RSATNNWDFWTLLPEALHQVTIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKFHFRTQQGIKNLTNEEAAKIIAD
DRESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKVPYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQSAFAP
SNLVPGVGASPDKMLQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRADGNYGSLPHYEPNSFGQWQQQPD
FAEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFGNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGVAKA
LGLTVEDAQAARATDPALGQPGLL
>Mature_503_residues
TTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTHDITKYTRA
KIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMR
SATNNWDFWTLLPEALHQVTIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKFHFRTQQGIKNLTNEEAAKIIADD
RESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKVPYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQSAFAPS
NLVPGVGASPDKMLQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRADGNYGSLPHYEPNSFGQWQQQPDF
AEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFGNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGVAKAL
GLTVEDAQAARATDPALGQPGLL

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=473, Percent_Identity=52.6427061310782, Blast_Score=506, Evalue=1e-143,
Organism=Escherichia coli, GI48994891, Length=497, Percent_Identity=42.4547283702213, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=49.8942917547569, Blast_Score=469, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI25151141, Length=473, Percent_Identity=48.2029598308668, Blast_Score=453, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI25147792, Length=473, Percent_Identity=47.9915433403806, Blast_Score=452, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6320462, Length=481, Percent_Identity=48.6486486486487, Blast_Score=408, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321525, Length=549, Percent_Identity=35.3369763205829, Blast_Score=303, Evalue=3e-83,
Organism=Drosophila melanogaster, GI17981717, Length=476, Percent_Identity=47.4789915966387, Blast_Score=451, Evalue=1e-127,
Organism=Drosophila melanogaster, GI19920968, Length=475, Percent_Identity=44.421052631579, Blast_Score=421, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 57194; Mature: 57062

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHA
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCC
KGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKF
CCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEE
YTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMRSATNNWDFWTLLPEALHQV
EEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCEE
TIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKFHFRTQQGIKNLTNEEAAKIIAD
EEEEECCCCCCCHHHHCCCCCHHHHHHHHCCCEEEEEEEEECHHHHHHCCHHHHHHHHHC
DRESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKVPYHPFDLTKVWPKKDYPLIEVGEF
CHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCE
ELNRNPENFFADVEQSAFAPSNLVPGVGASPDKMLQARLFNYADAQRYRLGVNFRQIPVN
EECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCEEECCCC
RPRCPVHSNQRDGQGRADGNYGSLPHYEPNSFGQWQQQPDFAEPPLKINGDAAHWDYRQD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
DDDYFSQPRALFNLMNDAQKQALFGNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGVAKA
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
LGLTVEDAQAARATDPALGQPGLL
HCCCCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHA
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCC
KGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKF
CCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEEE
YTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMRSATNNWDFWTLLPEALHQV
EEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCEE
TIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKFHFRTQQGIKNLTNEEAAKIIAD
EEEEECCCCCCCHHHHCCCCCHHHHHHHHCCCEEEEEEEEECHHHHHHCCHHHHHHHHHC
DRESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKVPYHPFDLTKVWPKKDYPLIEVGEF
CHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCE
ELNRNPENFFADVEQSAFAPSNLVPGVGASPDKMLQARLFNYADAQRYRLGVNFRQIPVN
EECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCEEECCCC
RPRCPVHSNQRDGQGRADGNYGSLPHYEPNSFGQWQQQPDFAEPPLKINGDAAHWDYRQD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
DDDYFSQPRALFNLMNDAQKQALFGNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGVAKA
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
LGLTVEDAQAARATDPALGQPGLL
HCCCCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8188593; 7542800 [H]