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The map label for this gene is aroE [H]

Identifier: 161870711

GI number: 161870711

Start: 1833515

End: 1834324

Strand: Direct

Name: aroE [H]

Synonym: NMCC_1783

Alternate gene names: 161870711

Gene position: 1833515-1834324 (Clockwise)

Preceding gene: 161870705

Following gene: 161870712

Centisome position: 85.14

GC content: 55.06

Gene sequence:

>810_bases
ATGACCGCCCTCCCCCGTTACTCCGTTTTCGGCAACCCCGTTGCACACAGTAAATCGCCGCAAATCCATCAGCAATTTGC
CCTTCAGGAAGGCGTTGACATTGAATACGAACGCATTTGCGCCGACATCGGCGGTTTCGCGCAGGCGGTTTCGACATTTT
TTGGAACAGGCGGTTGCGGGGCAAACGTTACCGTACCGTTCAAACAGGAAGCGTTTCATCTGGCGGACGAGCATTCCGAC
CGCGCTTTGGCAGCAGGTGCGGTCAATACGCTGATTCTGTTGAAAAACGGCAAGCTGCGTGGCGACAATACCGACGGTAT
CGGTTTGGCCAACGACATCACGCAGGTCAAAAACATTGCCATCGAGGGCAAAACCATTTTGCTTTTGGGCGCAGGCGGCG
CGGTGCGCGGCGTGATTCCGGTTTTGAAAGAACACCGCCCTGCCCGTATCGTCATTGCCAACCGTACCCGCGCCAAAGCC
GAGGAATTGGCGCAGCTTTTCGGCATTGAAGCCGTCCCGATGGCGGATGTGAACGGCGGTTTTGATATCATCATCAACGG
CACGTCCGGCGGTCTAAACGGTCAGATTCCCGATATTCCGCCCGATATTTTTCAAAACTGCGCGCTTGCCTACGATATGG
TGTACGGCTGCGCGGCAAAACCGTTTTTAGATTTTGCACGACAATCGGGTGCGAAAAAAACTGCCGACGGACTGGGTATG
CTAGTCGGTCAAGCGGCGGCTTCCTACGCCCTCTGGCGCGGATTTACGCCCGATATCCGCCCTGTTATCGAATACATGAA
AGCCATGTAA

Upstream 100 bases:

>100_bases
AAATATTCCGTCATGCTATCTGACAACCGTTTCAGACGGCATCGTTTCCATCTGTACGCCGCCGTTATAAAATAGCCTTC
CCGTCTTTTGGAACACGACC

Downstream 100 bases:

>100_bases
TATGTTCCGCATCGTCAAATGGCTGATTGCCCTGCCCGTCGGCATCTTTATCTTTTTCAATGCCTATGTGTACGGCAACA
TCATTACCTACCGCGCCGTC

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTALPRYSVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCGANVTVPFKQEAFHLADEHSD
RALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKA
EELAQLFGIEAVPMADVNGGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGM
LVGQAAASYALWRGFTPDIRPVIEYMKAM

Sequences:

>Translated_269_residues
MTALPRYSVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCGANVTVPFKQEAFHLADEHSD
RALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKA
EELAQLFGIEAVPMADVNGGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGM
LVGQAAASYALWRGFTPDIRPVIEYMKAM
>Mature_268_residues
TALPRYSVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCGANVTVPFKQEAFHLADEHSDR
ALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIAIEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAE
ELAQLFGIEAVPMADVNGGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGML
VGQAAASYALWRGFTPDIRPVIEYMKAM

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=267, Percent_Identity=50.936329588015, Blast_Score=253, Evalue=7e-69,
Organism=Escherichia coli, GI1787983, Length=277, Percent_Identity=29.9638989169675, Blast_Score=88, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=277, Percent_Identity=28.5198555956679, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28499; Mature: 28368

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALPRYSVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ANVTVPFKQEAFHLADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIA
CCEEECCHHHHHHHHCCCCCCCHHHCCCEEEEEEECCEECCCCCCCCCCHHHHHHHHHEE
IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVNGG
ECCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCC
FDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGM
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
LVGQAAASYALWRGFTPDIRPVIEYMKAM
HHHHHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TALPRYSVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIGGFAQAVSTFFGTGGCG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ANVTVPFKQEAFHLADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLANDITQVKNIA
CCEEECCHHHHHHHHCCCCCCCHHHCCCEEEEEEECCEECCCCCCCCCCHHHHHHHHHEE
IEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKAEELAQLFGIEAVPMADVNGG
ECCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCC
FDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCAAKPFLDFARQSGAKKTADGLGM
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
LVGQAAASYALWRGFTPDIRPVIEYMKAM
HHHHHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]