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The map label for this gene is ftsW [H]

Identifier: 161870653

GI number: 161870653

Start: 1767217

End: 1768542

Strand: Reverse

Name: ftsW [H]

Synonym: NMCC_1723

Alternate gene names: 161870653

Gene position: 1768542-1767217 (Counterclockwise)

Preceding gene: 161870654

Following gene: 161870652

Centisome position: 82.13

GC content: 53.24

Gene sequence:

>1326_bases
GTGCAAACAGACTGGCAGGTGGTTTTTTTGAAGATTTCGGAAGTATTGGTAAAAGTGGGCGACGGTGTCCACACTCTGCT
GCTCGACAGGCCGATTGTGCGCGACGGCAGGAAATTCGACGCGCCGCTTTTGTGGATGGTGGTGCTGATGACGGCGTTCA
GCCTGCTGATGATTTATTCGGCTTCTGTGTATTTGGCATCAAAAGAAGGCGGCGATCAGTTTTTCTATTTGACCAGACAG
GCGGGGTTCGTCGTTGCCGGCTTGATAGCGAGCGGTTTTTTATGGTTTCTTTGCAGGATGAGGACATGGCGGCGGCTTGT
GCCGTGGATTTTTGCCCTATCCGGCCTGTTGCTGGTAGTCGTATTGATTGCCGGGCGCGAAATCAATGGCGCGACCCGTT
GGATACCTTTGGGTCCGTTGAATTTCCAGCCGACCGAGCTGTTCAAGCTGGCGGTCATCCTTTATTTGGCAAGCCTGTTC
ACGCGCCGTGAAGAAGTGTTGCGCAGCATGGAAAGTTTGGGTTGGCAGTCGATTTGGCGGGGGACGGCCAATCTGATCAT
GTCCGCCACCAATCCGCAGGCACGTCGTGAAACATTAGAAATGTACGGCCGTTTCCGGGCGATCATCCTGCCGATTATGC
TGGTGGCGTTCGGTTTGGTGCTGATAATGGTACAGCCGGATTTCGGTTCGTTTGTCGTCATTACCGTCATTGCCGTTGGA
ATGCTGTTTTTGGCAGGATTGCCGTGGAAATATTTTTTCGTCCTGGTAGGCAGCGTCTTGGGCGGGATGGTGCTGATGAT
TACCGCCGCTCCCTACCGTGTGCAGCGGGTAGTGGCATTTTTGGACCCGTGGAAAGACCCGCAGGGTGCCGGCTACCAGC
TTACCCACTCTCTGATGGCAATCGGGCGCGGAGAGTGGTTCGGTATGGGTTTGGGTGCGAGTTTGAGCAAACGCGGCTTT
CTGCCGGAAGCGCATACCGATTTTATTTTTGCCATCATCGCCGAAGAATTCGGTTTCTTCGGTATGTGCGTGCTGATATT
CTGTTACGGCTGGCTGGTGGTGCGGGCGTTTTCCATCGGCAAGCAGTCGCGCGATTTGGGTTTGACTTTCAACGCCTATA
TCGCTTCGGGTATCGGCATTTGGATCGGTATCCAAAGTTTCTTCAATATCGGTGTGAACATCGGTGCTTTGCCGACCAAA
GGTCTGACGCTGCCGTTGATGTCCTATGGCGGTTCGTCAGTCTTTTTCATGCTGATCAGCATGATGCTGCTGTTGCGTAT
AGATTATGAAAACCGCCGGAAAATGCGCGGTTATCGGGTGGAGTAA

Upstream 100 bases:

>100_bases
ATTGTTGGGCGGCAAGTAAAGATTTAGAATACCGATTTGGGATGTATCGTATGTTCGGACGGCATTGTCTGCCGTCTGAA
ATTTTTGCCCTTTGCGGCAG

Downstream 100 bases:

>100_bases
ATCATGGGCGGTAAAACCTTTATGCTGATGGCGGGCGGAACGGGCGGACATATTTTCCCCGCGCTGGCGGTGGCGGATTC
ATTGCGCGCGCGCGGCCATC

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MQTDWQVVFLKISEVLVKVGDGVHTLLLDRPIVRDGRKFDAPLLWMVVLMTAFSLLMIYSASVYLASKEGGDQFFYLTRQ
AGFVVAGLIASGFLWFLCRMRTWRRLVPWIFALSGLLLVVVLIAGREINGATRWIPLGPLNFQPTELFKLAVILYLASLF
TRREEVLRSMESLGWQSIWRGTANLIMSATNPQARRETLEMYGRFRAIILPIMLVAFGLVLIMVQPDFGSFVVITVIAVG
MLFLAGLPWKYFFVLVGSVLGGMVLMITAAPYRVQRVVAFLDPWKDPQGAGYQLTHSLMAIGRGEWFGMGLGASLSKRGF
LPEAHTDFIFAIIAEEFGFFGMCVLIFCYGWLVVRAFSIGKQSRDLGLTFNAYIASGIGIWIGIQSFFNIGVNIGALPTK
GLTLPLMSYGGSSVFFMLISMMLLLRIDYENRRKMRGYRVE

Sequences:

>Translated_441_residues
MQTDWQVVFLKISEVLVKVGDGVHTLLLDRPIVRDGRKFDAPLLWMVVLMTAFSLLMIYSASVYLASKEGGDQFFYLTRQ
AGFVVAGLIASGFLWFLCRMRTWRRLVPWIFALSGLLLVVVLIAGREINGATRWIPLGPLNFQPTELFKLAVILYLASLF
TRREEVLRSMESLGWQSIWRGTANLIMSATNPQARRETLEMYGRFRAIILPIMLVAFGLVLIMVQPDFGSFVVITVIAVG
MLFLAGLPWKYFFVLVGSVLGGMVLMITAAPYRVQRVVAFLDPWKDPQGAGYQLTHSLMAIGRGEWFGMGLGASLSKRGF
LPEAHTDFIFAIIAEEFGFFGMCVLIFCYGWLVVRAFSIGKQSRDLGLTFNAYIASGIGIWIGIQSFFNIGVNIGALPTK
GLTLPLMSYGGSSVFFMLISMMLLLRIDYENRRKMRGYRVE
>Mature_441_residues
MQTDWQVVFLKISEVLVKVGDGVHTLLLDRPIVRDGRKFDAPLLWMVVLMTAFSLLMIYSASVYLASKEGGDQFFYLTRQ
AGFVVAGLIASGFLWFLCRMRTWRRLVPWIFALSGLLLVVVLIAGREINGATRWIPLGPLNFQPTELFKLAVILYLASLF
TRREEVLRSMESLGWQSIWRGTANLIMSATNPQARRETLEMYGRFRAIILPIMLVAFGLVLIMVQPDFGSFVVITVIAVG
MLFLAGLPWKYFFVLVGSVLGGMVLMITAAPYRVQRVVAFLDPWKDPQGAGYQLTHSLMAIGRGEWFGMGLGASLSKRGF
LPEAHTDFIFAIIAEEFGFFGMCVLIFCYGWLVVRAFSIGKQSRDLGLTFNAYIASGIGIWIGIQSFFNIGVNIGALPTK
GLTLPLMSYGGSSVFFMLISMMLLLRIDYENRRKMRGYRVE

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=394, Percent_Identity=38.8324873096447, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1786853, Length=406, Percent_Identity=30.7881773399015, Blast_Score=138, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 49503; Mature: 49503

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDWQVVFLKISEVLVKVGDGVHTLLLDRPIVRDGRKFDAPLLWMVVLMTAFSLLMIYS
CCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ASVYLASKEGGDQFFYLTRQAGFVVAGLIASGFLWFLCRMRTWRRLVPWIFALSGLLLVV
HHEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIAGREINGATRWIPLGPLNFQPTELFKLAVILYLASLFTRREEVLRSMESLGWQSIWR
HHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GTANLIMSATNPQARRETLEMYGRFRAIILPIMLVAFGLVLIMVQPDFGSFVVITVIAVG
HHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHH
MLFLAGLPWKYFFVLVGSVLGGMVLMITAAPYRVQRVVAFLDPWKDPQGAGYQLTHSLMA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
IGRGEWFGMGLGASLSKRGFLPEAHTDFIFAIIAEEFGFFGMCVLIFCYGWLVVRAFSIG
HCCCCEEECCCCCCCHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
KQSRDLGLTFNAYIASGIGIWIGIQSFFNIGVNIGALPTKGLTLPLMSYGGSSVFFMLIS
CCCCCCCCEEHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHH
MMLLLRIDYENRRKMRGYRVE
HHHHHHCCCHHHHHCCCCCCC
>Mature Secondary Structure
MQTDWQVVFLKISEVLVKVGDGVHTLLLDRPIVRDGRKFDAPLLWMVVLMTAFSLLMIYS
CCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ASVYLASKEGGDQFFYLTRQAGFVVAGLIASGFLWFLCRMRTWRRLVPWIFALSGLLLVV
HHEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIAGREINGATRWIPLGPLNFQPTELFKLAVILYLASLFTRREEVLRSMESLGWQSIWR
HHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GTANLIMSATNPQARRETLEMYGRFRAIILPIMLVAFGLVLIMVQPDFGSFVVITVIAVG
HHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHH
MLFLAGLPWKYFFVLVGSVLGGMVLMITAAPYRVQRVVAFLDPWKDPQGAGYQLTHSLMA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
IGRGEWFGMGLGASLSKRGFLPEAHTDFIFAIIAEEFGFFGMCVLIFCYGWLVVRAFSIG
HCCCCEEECCCCCCCHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
KQSRDLGLTFNAYIASGIGIWIGIQSFFNIGVNIGALPTKGLTLPLMSYGGSSVFFMLIS
CCCCCCCCEEHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHH
MMLLLRIDYENRRKMRGYRVE
HHHHHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]