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The map label for this gene is tyrA [H]

Identifier: 161870636

GI number: 161870636

Start: 1743363

End: 1744034

Strand: Direct

Name: tyrA [H]

Synonym: NMCC_1706

Alternate gene names: 161870636

Gene position: 1743363-1744034 (Clockwise)

Preceding gene: 161870634

Following gene: 161870639

Centisome position: 80.96

GC content: 59.97

Gene sequence:

>672_bases
TTGGTACTGATTGCCACGCCCGTCGCCACCGTTCCCGACATTTTGACCGCGCTGCGCCCCGTTTTGCCGGAACACACTTG
GATTTCCGATGTCGGCAGCACCAAATCTTCGGTCATCGAAGCCTTCCGCCGCTGTCTGCCCGACCGTCTGCACCACTGCA
TCGCCGCCCACCCAATTGCCGGTTCGGACAGAAGCGGTGCGCAAGCCGCGCAGTTCGGGCTGTTCCGCCACAGAAAACTC
ATCATCACGCCACACGGCGGCGAACATTCAGACGGCATTGCCTTGGTAGAAGAACTGTGGCACGCGGTCGGTGCGGAAAT
TTATACGATGGACGCGCAACGCCACGACGCGGTTTTCGCTGCCGTCTCCCATATGCCCCACCTGACCGCCTTCGCCTATG
TCCACCAGATTCTCGACCACCCCGACGGACAGGAATATCTGAAATTCGCCGCCACGGGCTTTCGGGACTTCACCCGCATC
GCCTCCGGTCATCCCGCCGTGTGGGCGGACATCTGCCTTGCCAACAAAGACAGCCTGCTGCAACTGGTTCAAGGCTTGGG
CAAACAGTTGGACGTTTTGGCAAACATCCTGACCACCGACGACCGCGAAGCCCTGTACCGCTATTTTGAAGAAGCCAAAA
CCACACGCGACCGCTGGCTGGACGGCAACTGA

Upstream 100 bases:

>100_bases
TATCGACACCGACCGCGACAACCTCGAACGTGCATTGGAACGCGGCGTGATTGACCGTGCGTCCGTTGCCATCGACGCGG
ACAGCATCGGCGGTGCGGAC

Downstream 100 bases:

>100_bases
CCGCCCTGCCGTCTGAAAAGCAAACCGCCCAGACCCGAAATCTGCGGCGGTTTGTCTCAACCGGGCCTGCCGTCCGAACG
CGGACGAATCAGCCAAGGAA

Product: prephenate dehydrogenase, putative

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MVLIATPVATVPDILTALRPVLPEHTWISDVGSTKSSVIEAFRRCLPDRLHHCIAAHPIAGSDRSGAQAAQFGLFRHRKL
IITPHGGEHSDGIALVEELWHAVGAEIYTMDAQRHDAVFAAVSHMPHLTAFAYVHQILDHPDGQEYLKFAATGFRDFTRI
ASGHPAVWADICLANKDSLLQLVQGLGKQLDVLANILTTDDREALYRYFEEAKTTRDRWLDGN

Sequences:

>Translated_223_residues
MVLIATPVATVPDILTALRPVLPEHTWISDVGSTKSSVIEAFRRCLPDRLHHCIAAHPIAGSDRSGAQAAQFGLFRHRKL
IITPHGGEHSDGIALVEELWHAVGAEIYTMDAQRHDAVFAAVSHMPHLTAFAYVHQILDHPDGQEYLKFAATGFRDFTRI
ASGHPAVWADICLANKDSLLQLVQGLGKQLDVLANILTTDDREALYRYFEEAKTTRDRWLDGN
>Mature_223_residues
MVLIATPVATVPDILTALRPVLPEHTWISDVGSTKSSVIEAFRRCLPDRLHHCIAAHPIAGSDRSGAQAAQFGLFRHRKL
IITPHGGEHSDGIALVEELWHAVGAEIYTMDAQRHDAVFAAVSHMPHLTAFAYVHQILDHPDGQEYLKFAATGFRDFTRI
ASGHPAVWADICLANKDSLLQLVQGLGKQLDVLANILTTDDREALYRYFEEAKTTRDRWLDGN

Specific function: Tyrosine biosynthesis [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR002912
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01842 ACT; PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 24718; Mature: 24718

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLIATPVATVPDILTALRPVLPEHTWISDVGSTKSSVIEAFRRCLPDRLHHCIAAHPIA
CEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GSDRSGAQAAQFGLFRHRKLIITPHGGEHSDGIALVEELWHAVGAEIYTMDAQRHDAVFA
CCCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHH
AVSHMPHLTAFAYVHQILDHPDGQEYLKFAATGFRDFTRIASGHPAVWADICLANKDSLL
HHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
QLVQGLGKQLDVLANILTTDDREALYRYFEEAKTTRDRWLDGN
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVLIATPVATVPDILTALRPVLPEHTWISDVGSTKSSVIEAFRRCLPDRLHHCIAAHPIA
CEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GSDRSGAQAAQFGLFRHRKLIITPHGGEHSDGIALVEELWHAVGAEIYTMDAQRHDAVFA
CCCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHH
AVSHMPHLTAFAYVHQILDHPDGQEYLKFAATGFRDFTRIASGHPAVWADICLANKDSLL
HHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHH
QLVQGLGKQLDVLANILTTDDREALYRYFEEAKTTRDRWLDGN
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3106153; 9384377 [H]