| Definition | Neisseria meningitidis 053442, complete genome. |
|---|---|
| Accession | NC_010120 |
| Length | 2,153,416 |
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The map label for this gene is tbpA [H]
Identifier: 161870612
GI number: 161870612
Start: 1713365
End: 1716109
Strand: Reverse
Name: tbpA [H]
Synonym: NMCC_1681
Alternate gene names: 161870612
Gene position: 1716109-1713365 (Counterclockwise)
Preceding gene: 161870613
Following gene: 161870610
Centisome position: 79.69
GC content: 53.11
Gene sequence:
>2745_bases ATGCAACAGCAACATTTGTTCCGATTAAATATTTTATGCCTGTCGCTGATGACTGCGCTGCCTGCTTATGCAGAAAATGT GCAAGCCGGACAAGCACAGGAAAAACAGTTGGATACCATACAGGTAAAAGCCAAAAAACAGAAAACCCGCCGCGATAACG AAGTAACCGGGCTGGGCAAGTTGGTCAAGTCTTCCGATACGCTAAGTAAAGAACAGGTTTTGAATATCCGAGACCTGACC CGTTATGATCCGGGTATTGCCGTGGTCGAACAGGGTCGGGGCGCAAGTTCCGGCTATTCAATACGCGGCATGGATAAAAA CCGCGTTTCCTTAACGGTGGACGGCGTTTCGCAAATACAGTCCTACACCGCGCAGGCGGCATTGGGCGGGACGAGGACGG CGGGCAGCAGCGGCGCAATCAATGAAATCGAGTATGAAAACGTCAAAGCTGTCGAAATCAGCAAAGGCTCAAACTCGGTC GAACAAGGCAGCGGCGCATTGGCGGGCTCGGTCGCATTTCAAACCAAAACCGCCGACGATGTTATCGGGGAAGGCAGGCA GTGGGGCATTCAGAGTAAAACCGCCTATTCCGGCAAAAACCGGGGGCTTACCCAATCCATCGCGCTGGCGGGGCGCATCG GCGGTGCGGAGGCTTTGCTGATCCACACCGGGCGGCGCGCGGGGGAAATCCGCGCCCACGAAGATGCAGGACGCGGCGTT CAGAGCTTTAACAGGCTGGTGCCGGTTGAGGATACCAATCAGTACGCTCATTTCGTGGTCGAAGAAGAATGCCCTAATGG ATATGCGGCTTGTAAAGACAAACCGAAAAAAGATGTTGTCGGCAAAGACGAACGTCAAACGGTTTCTACCCGAGACTACA CGGGTCCCAACCGCTTCCTCGCCGATCCGCTTTCATACGAAAGCCGGTCGTGGTTGTTCCGCCCGGGTTTTCGTTTTGAA AACAAACGGCACTACATCGGCGGCATACTCGAACACACGCAACAAACTTTCGACACGCGCGATATGACGGTTCCGGCATT CCTGACCAAGGCGGTTTTTGATGCAAATTCAAAACAGGCGGGTTCTTTGCCCGGTAACGGCAAATACGTGGGCAACCACA AATACGGCGGTCTGTTTACCAACGGTGAAAACGGTGCGCTGGTGGGCGCGGAATACGGTACGGGCGTGTTTTACGACGAG ACGCACACCAAAAGCCGCTACGGTTTGGAATATGTCTATACCAATGCCGATAAAGACACTTGGGCGGATTATGCCCGCCT CTCTTACGACCGTCAGGGCATCGGTTTGGACAATCATTTTCAGCAGACGCACTGTTCTGCCGACGGTTCGGACAAATATT GCCGTCCGAGTGCCGACAAGCCGTTTTCCTACTACAAATCCGACCGCGTGATTTACGGGGAAAGCCACAGGCTCTTGCAG GCGGCATTCAAAAAATCCTTCGATACCGCCAAAATCCGCCACAACCTGAGCGTGAATCTCGGGTTTGACCGCTTTGGCTC TAATCTGAGCCATCAGGATTATTATTATCAAAATGCCAACCGCGCCTATTCGTCGAAAACGCCCCCTAAAAACGGCAATA AAAACATCAGCCCCAACGGCAGCAAGGAAAAACCCTATTGGGTCAGCATAGGCGGGGGAAATGTGGTTACGGAGCAAATC TGCCGCTTGGGCAACAATACTTATACGGACTGCACGCCGCGCAGCATCAACGGCAAAAGCTATTACGCGGCAGTTCGGGA CAATGTCCGTTTGGGCAGGTGGGCGGATGTCGGCGCGGGGTTGCGCTACGACTACCGCAGTACGCATTCGGACGACGGCA GCGTTTCCACCGGCACGCACCGTACCCTGTCCTGGAACGCCGGCATCGTCCTCAAACCTGCCGACTGGCTGGATTTGACT TACCGCACTTCAACCGGCTTCCGCCTGCCCTCGTTTGCGGAAATGTACGGCTGGCGGGCGGGTGTTCAAAGCAAGGCGGT CAAAATCGATCCGGAAAAATCGTTCAACAAAGAAGCCGGCATCGTGTTTAAAGGCGATTTCGGCAACTTGGAGGCAAGTT GGTTCAATAATGCCTACCGCGATTTGATTGTCCGGGGTTATGAAGCGCAAATTAAAAACGGCAAAGAAGAAGCCAAAGGC GACCCGGCTTACCTCAATGCCCAAAGCGCGCGGATTACCGGCATCAATATTTTGGGCAAAATCGATTGGAACGGCGTATG GGATAAATTGCCCGAAGGTTGGTATTCTACATTTGCCTATAATCGTGTCCATGTCCGCGACATCAAAAAACGCGCAGACC GCACCGATATTCAATCACACCTGTTTGATGCCATCCAACCCTCGCGCTATGTCGTCGGCTTGGGCTATGACCAACCGGAA GGCAAATGGGGTGTGAACGGTATGCTGACTTATTCCAAAGCCAAGGAAATCACAGAGTTGTTGGGCAGCCGGGCTTTGCT CAACGGCAACAGCCGCAATACAAAAGCCACCGCGCGCCGTACCCGCCCTTGGTATATTGTGGATGTGTCCGGTTATTACA CGATTAAAAAACACTTCACCCTCCGTGCGGGCGTGTACAACCTTCTCAACTACCGCTATGTTACTTGGGAAAATGTGCGG CAAACTGCCGGCGGCGCAGTCAACCAACACAAAAATGTCGGCGTTTACAACCGATATGCCGCCCCCGGCCGAAACTACAC ATTTAGCTTGGAAATGAAGTTTTAA
Upstream 100 bases:
>100_bases AGCCTGTGCAATAAGCACGGTTGCCGAACAATCAAGAATAAGGCTTCAGACGGCACCGCTCCTTCCGATGCCGTCTGAAA GCGAAGATTAGGGAAACATT
Downstream 100 bases:
>100_bases ACGTCCAAACGCCGCAAATGCCGTCTGAAAGACTTCAGACGGCATTTTTTACACAATTCCCACCGTTTCCCATCATCCCC GACAATACCGTAATCTTGAA
Product: transferrin-binding protein A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 914; Mature: 914
Protein sequence:
>914_residues MQQQHLFRLNILCLSLMTALPAYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKSSDTLSKEQVLNIRDLT RYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSV EQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGV QSFNRLVPVEDTNQYAHFVVEEECPNGYAACKDKPKKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFE NKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANSKQAGSLPGNGKYVGNHKYGGLFTNGENGALVGAEYGTGVFYDE THTKSRYGLEYVYTNADKDTWADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQ AAFKKSFDTAKIRHNLSVNLGFDRFGSNLSHQDYYYQNANRAYSSKTPPKNGNKNISPNGSKEKPYWVSIGGGNVVTEQI CRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPADWLDLT YRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKNGKEEAKG DPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVHVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPE GKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNYRYVTWENVR QTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMKF
Sequences:
>Translated_914_residues MQQQHLFRLNILCLSLMTALPAYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKSSDTLSKEQVLNIRDLT RYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSV EQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGV QSFNRLVPVEDTNQYAHFVVEEECPNGYAACKDKPKKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFE NKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANSKQAGSLPGNGKYVGNHKYGGLFTNGENGALVGAEYGTGVFYDE THTKSRYGLEYVYTNADKDTWADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQ AAFKKSFDTAKIRHNLSVNLGFDRFGSNLSHQDYYYQNANRAYSSKTPPKNGNKNISPNGSKEKPYWVSIGGGNVVTEQI CRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPADWLDLT YRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKNGKEEAKG DPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVHVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPE GKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNYRYVTWENVR QTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMKF >Mature_914_residues MQQQHLFRLNILCLSLMTALPAYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKSSDTLSKEQVLNIRDLT RYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSV EQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGV QSFNRLVPVEDTNQYAHFVVEEECPNGYAACKDKPKKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFE NKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANSKQAGSLPGNGKYVGNHKYGGLFTNGENGALVGAEYGTGVFYDE THTKSRYGLEYVYTNADKDTWADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQ AAFKKSFDTAKIRHNLSVNLGFDRFGSNLSHQDYYYQNANRAYSSKTPPKNGNKNISPNGSKEKPYWVSIGGGNVVTEQI CRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPADWLDLT YRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKNGKEEAKG DPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVHVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPE GKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNYRYVTWENVR QTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMKF
Specific function: Acts as a transferrin receptor and is required for transferrin utilization [H]
COG id: COG1629
COG function: function code P; Outer membrane receptor proteins, mostly Fe transport
Gene ontology:
Cell location: Cell outer membrane [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the tonB-dependent receptor family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012910 - InterPro: IPR000531 - InterPro: IPR010916 - InterPro: IPR010949 - InterPro: IPR010948 - InterPro: IPR010917 [H]
Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]
EC number: NA
Molecular weight: Translated: 101827; Mature: 101827
Theoretical pI: Translated: 9.73; Mature: 9.73
Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQQQHLFRLNILCLSLMTALPAYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGK CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEHHHHHHCCCCHHHHHHH LVKSSDTLSKEQVLNIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQ HHHCCCCCCHHHHCCHHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEEEEEECCHHHHH SYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADD HHHHHHHCCCCCCCCCCCCCCCEECCCEEEEEEECCCCCHHHCCCCEEEEEEEECCCHHH VIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGV HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEECCHHCCCH QSFNRLVPVEDTNQYAHFVVEEECPNGYAACKDKPKKDVVGKDERQTVSTRDYTGPNRFL HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC ADPLSYESRSWLFRPGFRFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANSKQA CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC GSLPGNGKYVGNHKYGGLFTNGENGALVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDT CCCCCCCEEECCCCCCCEEECCCCCEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCHH WADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQ HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCHHHHH AAFKKSFDTAKIRHNLSVNLGFDRFGSNLSHQDYYYQNANRAYSSKTPPKNGNKNISPNG HHHHCCCCCEEEEECEEEEECHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC SKEKPYWVSIGGGNVVTEQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAG CCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCC LRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPADWLDLTYRTSTGFRLPSFAEMYGWRA CEECCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCEEEEEECCCCCCCCCHHHHHHHHC GVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKNGKEEAKG CCCCCEEEECCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHCCCCHHHHCCCHHHCCC DPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVHVRDIKKRADRTDIQSH CCCEEECCCCEEEEEEEEEEECCCCHHHHCCCCHHHHHHCCEEHHHHHHHHHCHHHHHHH LFDAIQPSRYVVGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARR HHHHCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEECCCCCCCCHHHHC TRPWYIVDVSGYYTIKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYA CCCEEEEECCCEEEEEEEEEEHHHHHHHHCEEEEEHHHHHHHCCCCCCCCCCCCCEEEEC APGRNYTFSLEMKF CCCCCEEEEEEECC >Mature Secondary Structure MQQQHLFRLNILCLSLMTALPAYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGK CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEHHHHHHCCCCHHHHHHH LVKSSDTLSKEQVLNIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQ HHHCCCCCCHHHHCCHHHHHHCCCCEEEEECCCCCCCCCEEECCCCCEEEEEECCHHHHH SYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADD HHHHHHHCCCCCCCCCCCCCCCEECCCEEEEEEECCCCCHHHCCCCEEEEEEEECCCHHH VIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGV HHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEECCHHCCCH QSFNRLVPVEDTNQYAHFVVEEECPNGYAACKDKPKKDVVGKDERQTVSTRDYTGPNRFL HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC ADPLSYESRSWLFRPGFRFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANSKQA CCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC GSLPGNGKYVGNHKYGGLFTNGENGALVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDT CCCCCCCEEECCCCCCCEEECCCCCEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCHH WADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQ HHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCHHHHH AAFKKSFDTAKIRHNLSVNLGFDRFGSNLSHQDYYYQNANRAYSSKTPPKNGNKNISPNG HHHHCCCCCEEEEECEEEEECHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC SKEKPYWVSIGGGNVVTEQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAG CCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCC LRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPADWLDLTYRTSTGFRLPSFAEMYGWRA CEECCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCEEEEEECCCCCCCCCHHHHHHHHC GVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKNGKEEAKG CCCCCEEEECCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHCCCCHHHHCCCHHHCCC DPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVHVRDIKKRADRTDIQSH CCCEEECCCCEEEEEEEEEEECCCCHHHHCCCCHHHHHHCCEEHHHHHHHHHCHHHHHHH LFDAIQPSRYVVGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARR HHHHCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEECCCCCCCCHHHHC TRPWYIVDVSGYYTIKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYA CCCEEEEECCCEEEEEEEEEEHHHHHHHHCEEEEEHHHHHHHCCCCCCCCCCCCCEEEEC APGRNYTFSLEMKF CCCCCEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1325963 [H]