| Definition | Neisseria meningitidis 053442, complete genome. |
|---|---|
| Accession | NC_010120 |
| Length | 2,153,416 |
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The map label for this gene is secA [H]
Identifier: 161870397
GI number: 161870397
Start: 1462617
End: 1465367
Strand: Direct
Name: secA [H]
Synonym: NMCC_1444
Alternate gene names: 161870397
Gene position: 1462617-1465367 (Clockwise)
Preceding gene: 161870385
Following gene: 161870398
Centisome position: 67.92
GC content: 55.11
Gene sequence:
>2751_bases ATGCTGACAAACATTGCCAAGAAAATCTTCGGCAGCCGCAACGACCGCTTGCTGAAACAATACCGTAAATCCGTTGCCAG AATCAACGCGCTCGAAGAACAGATGCAAGCCCTAAGCGATGCTGATCTGCAAGCCAAAACTGCCGAATTCAAACAACGCC TCGCCGACGGTCAGACTTTGGACGGCATTTTGCCCGAAGCCTTCGCCGTCTGCCGCGAAGCGTCCCGCCGCACCCTCGGT ATGCGCCACTTCGACGTGCAGCTTATCGGCGGTATGGTGCTGCACGACGGCAAAATCGCCGAAATGCGTACCGGCGAAGG CAAAACCCTGGTCGCCACCCTCGCCGTCTATCTCAACGCGCTGGCCGGCAAAGGCGTACACGTCGTTACCGTCAACGACT ACCTCGCCTCACGCGATGCGGGCATTATGGAGCCGCTCTATAATTTCCTCGGTCTGACCGTCGGCGTGATTATTTCAGAT ATGCAGCCGTTCGACCGTCAAAACGCCTATGCCGCCGATATCACCTACGGCACCAATAATGAATTCGGCTTCGACTACCT GCGCGACAATATGGTTACCGACCAATACGACAAAGTGCAGCGCGAATTGAATTTTGCCGTTGTCGATGAAGTGGATTCCA TCTTGATTGACGAAGCGCGCACTCCGCTGATTATCTCCGGTCAGGCGGATGACAACATCCAGTTGTACCAAATCATGAAC ACCGTTCCGCCCCACCTCGTCCGTCAAGAGACAGAAGAAGGCGAAGGCGACTATTGGGTCGACGAAAAGGCACATCAGGT CATCCTGAGCGAAGCAGGTCACGAACACGCCGAGCAAATCCTGACCCAAATGGGATTGCTGGCAGAAAACGACTCCCTCT ATTCCGCCGCCAATATCGCCCTGATGCACCACCTTATGGCGGCATTGCGCGCGCATTCCCTCTTCCACAAAGACCAACAT TACGTCATCCAAGACGGCGAAATCGTCATCGTGGACGAATTCACCGGCCGGCTGATGTCCGGCCGCCGCTGGTCGGAGGG TCTGCATCAAGCCGTCGAAGCCAAAGAAGGCGTGGAAATCAAACGCGAAAACCAAACCCTTGCCTCCATCACCTTCCAAA ACTATTTCCGCCTGTACACCAAGCTCTCCGGCATGACCGGCACAGCCGATACCGAAGCTTTCGAGTTCCAAAGCATCTAC AACCTCGAAACCGTCATCATCCCGACCAACCGCCCTGTACAGCGCAAAGACTTCAACGACCAGATTTTCCGTTCCGCCGA AGAAAAATTCGAAGCCGTCGTCAAAGACATCGAAGAATGCCACAAACGTGGGCAGCCCGTCCTCGTCGGCACCACCAGCA TCGAAAACTCCGAACTGGTCTCCCACCTTCTGCAAAAAGCCGGACTGCCGCACAACGTCCTCAACGCCAAAGAACACGAA CGCGAAGCCCTGATTGTCGCCCAAGCCGGCAAAGTCGGCGCGATTACCGTTGCCACCAATATGGCGGGACGCGGTACGGA CATCGTTTTAGGCGGCAACCTGAAGCACCAAACCGATGCCATCCGTGCCGACGAAACCTTGAGCGACGAAGAGAAACAGG CACAAATCGCCGCACTCGAAAACGGCTGGCAGGCAGAACACGATAAAGTAATGGAAGCAGGCGGCCTGCACATCATCGGT ACGGAACGCCACGAAAGCCGCCGTATCGACAACCAATTGCGCGGACGTTCCGGCCGTCAGGGCGACCCCGGATCCAGCCG TTTCTACCTTTCGTTTGAAGACCCGCTGCTGCGCTTATTCGCACTCGACCGCGCCGCCGCCATCCTCAACCGTCTCGCCC CCGAACGCGGCGTTGCCATCGAACACAACCTGCTGACGCGCCAAATCGAAGGGGCGCAACGCAAAGTCGAAGGCAGAAAC TTCGATATGCGCAAACAGGTTTTGGAATACGACGACGTTGCCAACGAACAGCGCAAAGTCATTTACAGCCAGCGCAACGA AATTCTGACCAGCAAAGACATCAGCGACCTGATGCAGGAAATCCGTTCTGATGTCGTCAGCGACCTCGTGGATACCTATA TGCCTCCCGACAGCATGGAAGAACAATGGGACATCCCGACTTTGGAGAACCGTCTGGCTGCCGAATTCAGACTGCACGAA GACATCCAATCCTGGCTGAAGGCGGACAATGCGATTGACGGTCAAGACATCAAAGAACGCCTGATCGAACGCATCGAAAA CGAATATGCCGCCAAAACCGAACTGGTCGGCAAGCAGGCAATGGCCGATTTCGAGCGCAACGTGATGTTGCAGGTCATCG ACAACCAATGGCGCGAACACCTCGCCGCTATGGACTACCTGCGACAAGGCATACACCTGCGCAGCTATGCCCAAAAAAAT CCGAAGCAGGAATATAAACGTGAAGCCTTTACCATGTTCCAAGACCTGTGGAACGGCATCAAATTCCATATTGCCTCCCT GCTTACCTCGGTTCAAATCGAACAAAACCCTGTCGCGGTGGTTGAAGAGCAACCCATCGGCAACATCCAATCCATCCATT CCGAATCGCCCGATATGGAAGAACTTTTGGGTCAGTCGCAAACCGATCTGGTTACCGAAGCCTTTAATCCCGATGGAACG GATTTCAGCCCCGAAGCCTTGGAAGCGCGGGGACAAATCGTCCACCGCAACGACCCCTGCCCCTGCGGCAGCGGTTTGAA ATACAAACAATGCCACGGCAAACTGGCTTGA
Upstream 100 bases:
>100_bases TCAAACGCGCCTTTATTTCAGACGGCATTAGCACTTTGCACAAACGCTTGTGTTAAAATCGCGTTTTCGCCCACTATTAT ATCAGGCGCAGGAATTATTC
Downstream 100 bases:
>100_bases GCGTTTGAACGCAAATGCCGTCTGAACATCCGGTTTCCGGCTTCAGACGGCATTTTGCCTGAACCGCCACATCCGACTGC CATTCCGAAAAATCCCGATT
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 916; Mature: 916
Protein sequence:
>916_residues MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQAKTAEFKQRLADGQTLDGILPEAFAVCREASRRTLG MRHFDVQLIGGMVLHDGKIAEMRTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISD MQPFDRQNAYAADITYGTNNEFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDEARTPLIISGQADDNIQLYQIMN TVPPHLVRQETEEGEGDYWVDEKAHQVILSEAGHEHAEQILTQMGLLAENDSLYSAANIALMHHLMAALRAHSLFHKDQH YVIQDGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVEIKRENQTLASITFQNYFRLYTKLSGMTGTADTEAFEFQSIY NLETVIIPTNRPVQRKDFNDQIFRSAEEKFEAVVKDIEECHKRGQPVLVGTTSIENSELVSHLLQKAGLPHNVLNAKEHE REALIVAQAGKVGAITVATNMAGRGTDIVLGGNLKHQTDAIRADETLSDEEKQAQIAALENGWQAEHDKVMEAGGLHIIG TERHESRRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLFALDRAAAILNRLAPERGVAIEHNLLTRQIEGAQRKVEGRN FDMRKQVLEYDDVANEQRKVIYSQRNEILTSKDISDLMQEIRSDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHE DIQSWLKADNAIDGQDIKERLIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREHLAAMDYLRQGIHLRSYAQKN PKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAVVEEQPIGNIQSIHSESPDMEELLGQSQTDLVTEAFNPDGT DFSPEALEARGQIVHRNDPCPCGSGLKYKQCHGKLA
Sequences:
>Translated_916_residues MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQAKTAEFKQRLADGQTLDGILPEAFAVCREASRRTLG MRHFDVQLIGGMVLHDGKIAEMRTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISD MQPFDRQNAYAADITYGTNNEFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDEARTPLIISGQADDNIQLYQIMN TVPPHLVRQETEEGEGDYWVDEKAHQVILSEAGHEHAEQILTQMGLLAENDSLYSAANIALMHHLMAALRAHSLFHKDQH YVIQDGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVEIKRENQTLASITFQNYFRLYTKLSGMTGTADTEAFEFQSIY NLETVIIPTNRPVQRKDFNDQIFRSAEEKFEAVVKDIEECHKRGQPVLVGTTSIENSELVSHLLQKAGLPHNVLNAKEHE REALIVAQAGKVGAITVATNMAGRGTDIVLGGNLKHQTDAIRADETLSDEEKQAQIAALENGWQAEHDKVMEAGGLHIIG TERHESRRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLFALDRAAAILNRLAPERGVAIEHNLLTRQIEGAQRKVEGRN FDMRKQVLEYDDVANEQRKVIYSQRNEILTSKDISDLMQEIRSDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHE DIQSWLKADNAIDGQDIKERLIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREHLAAMDYLRQGIHLRSYAQKN PKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAVVEEQPIGNIQSIHSESPDMEELLGQSQTDLVTEAFNPDGT DFSPEALEARGQIVHRNDPCPCGSGLKYKQCHGKLA >Mature_916_residues MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQAKTAEFKQRLADGQTLDGILPEAFAVCREASRRTLG MRHFDVQLIGGMVLHDGKIAEMRTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISD MQPFDRQNAYAADITYGTNNEFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDEARTPLIISGQADDNIQLYQIMN TVPPHLVRQETEEGEGDYWVDEKAHQVILSEAGHEHAEQILTQMGLLAENDSLYSAANIALMHHLMAALRAHSLFHKDQH YVIQDGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVEIKRENQTLASITFQNYFRLYTKLSGMTGTADTEAFEFQSIY NLETVIIPTNRPVQRKDFNDQIFRSAEEKFEAVVKDIEECHKRGQPVLVGTTSIENSELVSHLLQKAGLPHNVLNAKEHE REALIVAQAGKVGAITVATNMAGRGTDIVLGGNLKHQTDAIRADETLSDEEKQAQIAALENGWQAEHDKVMEAGGLHIIG TERHESRRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLFALDRAAAILNRLAPERGVAIEHNLLTRQIEGAQRKVEGRN FDMRKQVLEYDDVANEQRKVIYSQRNEILTSKDISDLMQEIRSDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHE DIQSWLKADNAIDGQDIKERLIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREHLAAMDYLRQGIHLRSYAQKN PKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAVVEEQPIGNIQSIHSESPDMEELLGQSQTDLVTEAFNPDGT DFSPEALEARGQIVHRNDPCPCGSGLKYKQCHGKLA
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=920, Percent_Identity=57.9347826086957, Blast_Score=1070, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 103331; Mature: 103331
Theoretical pI: Translated: 4.88; Mature: 4.88
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQAKTAEFKQRLADGQTL CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC DGILPEAFAVCREASRRTLGMRHFDVQLIGGMVLHDGKIAEMRTGEGKTLVATLAVYLNA CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCCEEEEECCCCCHHHHHHHHHHHH LAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISDMQPFDRQNAYAADITYGTNN HCCCCEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC EFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDEARTPLIISGQADDNIQLYQIMN CCCHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH TVPPHLVRQETEEGEGDYWVDEKAHQVILSEAGHEHAEQILTQMGLLAENDSLYSAANIA CCCHHHHHHCCCCCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHH LMHHLMAALRAHSLFHKDQHYVIQDGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVEI HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCE KRENQTLASITFQNYFRLYTKLSGMTGTADTEAFEFQSIYNLETVIIPTNRPVQRKDFND EECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCH QIFRSAEEKFEAVVKDIEECHKRGQPVLVGTTSIENSELVSHLLQKAGLPHNVLNAKEHE HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCCHHHC REALIVAQAGKVGAITVATNMAGRGTDIVLGGNLKHQTDAIRADETLSDEEKQAQIAALE CCEEEEEECCCCEEEEEEECCCCCCCEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHH NGWQAEHDKVMEAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLF CCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHH ALDRAAAILNRLAPERGVAIEHNLLTRQIEGAQRKVEGRNFDMRKQVLEYDDVANEQRKV HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHH IYSQRNEILTSKDISDLMQEIRSDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHH DIQSWLKADNAIDGQDIKERLIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREH HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LAAMDYLRQGIHLRSYAQKNPKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAV HHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE VEEQPIGNIQSIHSESPDMEELLGQSQTDLVTEAFNPDGTDFSPEALEARGQIVHRNDPC EECCCCCCHHHHCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHCCCEEECCCCC PCGSGLKYKQCHGKLA CCCCCCCHHHHCCCCC >Mature Secondary Structure MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQAKTAEFKQRLADGQTL CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC DGILPEAFAVCREASRRTLGMRHFDVQLIGGMVLHDGKIAEMRTGEGKTLVATLAVYLNA CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCCEEEEECCCCCHHHHHHHHHHHH LAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISDMQPFDRQNAYAADITYGTNN HCCCCEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC EFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDEARTPLIISGQADDNIQLYQIMN CCCHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH TVPPHLVRQETEEGEGDYWVDEKAHQVILSEAGHEHAEQILTQMGLLAENDSLYSAANIA CCCHHHHHHCCCCCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHH LMHHLMAALRAHSLFHKDQHYVIQDGEIVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVEI HHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCE KRENQTLASITFQNYFRLYTKLSGMTGTADTEAFEFQSIYNLETVIIPTNRPVQRKDFND EECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCH QIFRSAEEKFEAVVKDIEECHKRGQPVLVGTTSIENSELVSHLLQKAGLPHNVLNAKEHE HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHCCHHHC REALIVAQAGKVGAITVATNMAGRGTDIVLGGNLKHQTDAIRADETLSDEEKQAQIAALE CCEEEEEECCCCEEEEEEECCCCCCCEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHH NGWQAEHDKVMEAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLF CCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHH ALDRAAAILNRLAPERGVAIEHNLLTRQIEGAQRKVEGRNFDMRKQVLEYDDVANEQRKV HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHH IYSQRNEILTSKDISDLMQEIRSDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHH DIQSWLKADNAIDGQDIKERLIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREH HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LAAMDYLRQGIHLRSYAQKNPKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAV HHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE VEEQPIGNIQSIHSESPDMEELLGQSQTDLVTEAFNPDGTDFSPEALEARGQIVHRNDPC EECCCCCCHHHHCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHCCCEEECCCCC PCGSGLKYKQCHGKLA CCCCCCCHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA