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The map label for this gene is gph [C]

Identifier: 161870346

GI number: 161870346

Start: 1410785

End: 1411492

Strand: Direct

Name: gph [C]

Synonym: NMCC_1390

Alternate gene names: 161870346

Gene position: 1410785-1411492 (Clockwise)

Preceding gene: 161870343

Following gene: 161870347

Centisome position: 65.51

GC content: 57.34

Gene sequence:

>708_bases
ATGAATGCAGCCATCGAACACGTCCAAGCCGTCGCCTTCGATTTGGACGGCACACTGTGCGATTCCGTCCCCGACCTTGC
CGCCGCCGCAGAAGCGATGTTGGAACAACTCGGTATGAAACCGCTGCCCGCCAAAGTGGTCGAAAGCTATGTGGGCGACG
GCATCGGCAAACTGGTTCACCGCGTCCTCACCAACGACCGCGACCGCGAAGCCGATTCCGAACTGTGGGAAAAAGGTTTC
GTATCCTATATGAAATACTACCGCGACCATTTGAGCGTCTTCACCCGCCCCTATCCCGAAACCGAAGCCGGGCTGGCATT
GCTCAAATCTTTGGGCATCCCGCTGGCAGTCATTACCAACAAAAACGAAATCCTTGCCGTCGAACTGTTGAAACAGCTCG
GACTTGCCGACTACTTCAGCCTGATACTCGGCGGCGACAGCCTGCCCGAGAAAAAACCCAGCCCCCTGCCGCTGCGGCAC
GCCGCCGAAGTTTTGGGTATCGATGTTGCAAACATGGTTATGGTCGGCGACTCGCGCAACGACATCATCGCCGCCAAAGC
CGCCGGCTGCCTGAGCGTCGGCGTTACCTTCGGTTACGGCGATATGACGCTGCTCTCGCAAGACGATGCGACCCGCCCCG
ACTGGATTATCGGCTCGCTGCCCGAAATTTACGACAACCTGCAACCTCAGAAAAACAAAGAAGAGTAG

Upstream 100 bases:

>100_bases
CGCCTGCAAAACCTGTTGCGATTGTTAACAATCTATACATTAGAAGCCCTGTGCAAACGATGTTAAAATAAACCCTTTCA
ACCCGACAGGAAATCAGATT

Downstream 100 bases:

>100_bases
GCATTCGGACGGCTCCGGTTTGCGCCGCTATGCCGTCTGAAACCTGCCCCACGCCGAAACCGCCGCCATGAAACCGCAAA
AATCCCTACGCGCCCGCGCG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPAKVVESYVGDGIGKLVHRVLTNDRDREADSELWEKGF
VSYMKYYRDHLSVFTRPYPETEAGLALLKSLGIPLAVITNKNEILAVELLKQLGLADYFSLILGGDSLPEKKPSPLPLRH
AAEVLGIDVANMVMVGDSRNDIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIGSLPEIYDNLQPQKNKEE

Sequences:

>Translated_235_residues
MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPAKVVESYVGDGIGKLVHRVLTNDRDREADSELWEKGF
VSYMKYYRDHLSVFTRPYPETEAGLALLKSLGIPLAVITNKNEILAVELLKQLGLADYFSLILGGDSLPEKKPSPLPLRH
AAEVLGIDVANMVMVGDSRNDIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIGSLPEIYDNLQPQKNKEE
>Mature_235_residues
MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPAKVVESYVGDGIGKLVHRVLTNDRDREADSELWEKGF
VSYMKYYRDHLSVFTRPYPETEAGLALLKSLGIPLAVITNKNEILAVELLKQLGLADYFSLILGGDSLPEKKPSPLPLRH
AAEVLGIDVANMVMVGDSRNDIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIGSLPEIYDNLQPQKNKEE

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=223, Percent_Identity=39.9103139013453, Blast_Score=137, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25542; Mature: 25542

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPAKVVESYVGDGIGKLVH
CCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
RVLTNDRDREADSELWEKGFVSYMKYYRDHLSVFTRPYPETEAGLALLKSLGIPLAVITN
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEC
KNEILAVELLKQLGLADYFSLILGGDSLPEKKPSPLPLRHAAEVLGIDVANMVMVGDSRN
CCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHEEEECCCCC
DIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIGSLPEIYDNLQPQKNKEE
CEEHHHHCCHHHHCEEECCCCEEEECCCCCCCCCHHHCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPAKVVESYVGDGIGKLVH
CCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
RVLTNDRDREADSELWEKGFVSYMKYYRDHLSVFTRPYPETEAGLALLKSLGIPLAVITN
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEC
KNEILAVELLKQLGLADYFSLILGGDSLPEKKPSPLPLRHAAEVLGIDVANMVMVGDSRN
CCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHEEEECCCCC
DIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIGSLPEIYDNLQPQKNKEE
CEEHHHHCCHHHHCEEECCCCEEEECCCCCCCCCHHHCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA