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The map label for this gene is polC [H]

Identifier: 161870321

GI number: 161870321

Start: 1380887

End: 1382272

Strand: Reverse

Name: polC [H]

Synonym: NMCC_1363

Alternate gene names: 161870321

Gene position: 1382272-1380887 (Counterclockwise)

Preceding gene: 161870323

Following gene: 161870319

Centisome position: 64.19

GC content: 49.06

Gene sequence:

>1386_bases
ATGATTGTTGCTTCCCGCTGGCCCTTGCTGGAAAAGGTATTTTTACGGTTTGGAATGCCTGTTGCCGTGGTCGATTTGGA
ATCGACGGGCGGCAATCTGTATGAAGACAGGGTAACCGAAGTGGCTTTGGTCAAGTTTGAGCAGGGAAGGGTGGTGAGGC
ATGAGTGGTTGGTTAATCCTCAAAAACCGATTCCGCAGTTTGTGGCGGGGCTGACGGGGATTTCAGACGGCATGGTTGCC
GATGCGCCTGTTTTTGCAGAGATTGCCGGCGAGTTGTTTTCGGTATTGAAGGGTTGTGTGCTGGTTGCACATAACAGCCG
TTTCGACTATACGTTTTTAAAGCATGAGTTTCATCGTGTGGGTATCGGATTTTCATCGCCTGCTTTGTGCAGTGTGCAGC
TGTCCCGGTGTCTGTATCCGCAATTTTACAAGCACAGCCTGGACAGTATCATCGAAAGGTTGGGGATTGTTGTGGAAGAC
AGGCATCGTGCGATGGCGGATGTGTCGGCATTGTGTGATTATTTGGAATACAGTCTGTCGGAACACGGGGTTGAGGAGTG
GATTAGGCAGTGTTTCCGTTTGATGAATCCGAAACCGCTGCCTGCCGCGCTGCCCGAACGGTTGAGGGAACAGTTGTACG
GTTTGCCTGACGGTATGGGGGTGCTGGCTTGTTTCGACGGCGGAGGGAAAGTAAATTACATCGGTACGTTTGAACGGGTA
TATAGCGAGGTTTCGGCTTTATTGGATTCCGGAAAAGCCCCGTTTGATTGGTGCAATACGGAGGAAGTCCGTTTTTTTCC
CGCATTGGGCAGCCTGCATGCATATAAGATTAAAGCGGAATTGGTCGGGCGTTATCATTCGGGTTGTTATGTATCTGCCA
AAAATCTGCTTAAAACATTTACGACCGTCAGGTTTGAAAAAGGTTCAGACGGCATGTTGAATGCGAAAACAGCGGCTTTG
AAAAACGGTGTGACGGATAATCCGCCTACCGGATTATTTTCCAATAAAAAGGCGGCGAGACGGGCTTTGTCGTCGTGGGC
GGAAACATACGGATTGTGTCCTGCCTCAGCCGGTATCCTTCCGGATGGTTATGCAGAGGATGAGCCCTGTTCCGTATATG
TTTCAGGCCGATGCGATAAGGCGTGCGGCCGTTCTGACGAACAGGTTTTGGCGTTTGCACACAAGTTGCCTATTTTGGAT
TGGGGAAAAATGCATGAGGTGGAAATTACCGAAACCGATCCTTTAACGGGGGAAAAAGTTGTTCTGCATGGAATGGGCGG
CGCATTGGAAATGGATGACGGGTTTTGGTATTTCGATAAAGATTTACCGGATGCGTTTAAGGCGAAGTTTAAAACGGACA
GGAAAAATATTAAGGAAATCGGTTAA

Upstream 100 bases:

>100_bases
AATTTTAGGGTAATCATCGGATTCTGTCAATTGTTTTGTTGGATGAAATGCCTTAAAAGTGTAAAATATCGGTTTGTTGT
TTGAATTTAAAGAGAATAAA

Downstream 100 bases:

>100_bases
ATCGATACCGGTTGGTGAAAGCCGGTAAGTATGTAAACAGCCGTTCGTATTGATTGCCTAATCGGTTTGGGTTGGAATGT
GTTGCCGTTTGTATGTATCC

Product: putative DNA polymerase III subunit

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MIVASRWPLLEKVFLRFGMPVAVVDLESTGGNLYEDRVTEVALVKFEQGRVVRHEWLVNPQKPIPQFVAGLTGISDGMVA
DAPVFAEIAGELFSVLKGCVLVAHNSRFDYTFLKHEFHRVGIGFSSPALCSVQLSRCLYPQFYKHSLDSIIERLGIVVED
RHRAMADVSALCDYLEYSLSEHGVEEWIRQCFRLMNPKPLPAALPERLREQLYGLPDGMGVLACFDGGGKVNYIGTFERV
YSEVSALLDSGKAPFDWCNTEEVRFFPALGSLHAYKIKAELVGRYHSGCYVSAKNLLKTFTTVRFEKGSDGMLNAKTAAL
KNGVTDNPPTGLFSNKKAARRALSSWAETYGLCPASAGILPDGYAEDEPCSVYVSGRCDKACGRSDEQVLAFAHKLPILD
WGKMHEVEITETDPLTGEKVVLHGMGGALEMDDGFWYFDKDLPDAFKAKFKTDRKNIKEIG

Sequences:

>Translated_461_residues
MIVASRWPLLEKVFLRFGMPVAVVDLESTGGNLYEDRVTEVALVKFEQGRVVRHEWLVNPQKPIPQFVAGLTGISDGMVA
DAPVFAEIAGELFSVLKGCVLVAHNSRFDYTFLKHEFHRVGIGFSSPALCSVQLSRCLYPQFYKHSLDSIIERLGIVVED
RHRAMADVSALCDYLEYSLSEHGVEEWIRQCFRLMNPKPLPAALPERLREQLYGLPDGMGVLACFDGGGKVNYIGTFERV
YSEVSALLDSGKAPFDWCNTEEVRFFPALGSLHAYKIKAELVGRYHSGCYVSAKNLLKTFTTVRFEKGSDGMLNAKTAAL
KNGVTDNPPTGLFSNKKAARRALSSWAETYGLCPASAGILPDGYAEDEPCSVYVSGRCDKACGRSDEQVLAFAHKLPILD
WGKMHEVEITETDPLTGEKVVLHGMGGALEMDDGFWYFDKDLPDAFKAKFKTDRKNIKEIG
>Mature_461_residues
MIVASRWPLLEKVFLRFGMPVAVVDLESTGGNLYEDRVTEVALVKFEQGRVVRHEWLVNPQKPIPQFVAGLTGISDGMVA
DAPVFAEIAGELFSVLKGCVLVAHNSRFDYTFLKHEFHRVGIGFSSPALCSVQLSRCLYPQFYKHSLDSIIERLGIVVED
RHRAMADVSALCDYLEYSLSEHGVEEWIRQCFRLMNPKPLPAALPERLREQLYGLPDGMGVLACFDGGGKVNYIGTFERV
YSEVSALLDSGKAPFDWCNTEEVRFFPALGSLHAYKIKAELVGRYHSGCYVSAKNLLKTFTTVRFEKGSDGMLNAKTAAL
KNGVTDNPPTGLFSNKKAARRALSSWAETYGLCPASAGILPDGYAEDEPCSVYVSGRCDKACGRSDEQVLAFAHKLPILD
WGKMHEVEITETDPLTGEKVVLHGMGGALEMDDGFWYFDKDLPDAFKAKFKTDRKNIKEIG

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 51177; Mature: 51177

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVASRWPLLEKVFLRFGMPVAVVDLESTGGNLYEDRVTEVALVKFEQGRVVRHEWLVNP
CEECCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHEEEEEECCCCEEEHHHCCCC
QKPIPQFVAGLTGISDGMVADAPVFAEIAGELFSVLKGCVLVAHNSRFDYTFLKHEFHRV
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHC
GIGFSSPALCSVQLSRCLYPQFYKHSLDSIIERLGIVVEDRHRAMADVSALCDYLEYSLS
CCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EHGVEEWIRQCFRLMNPKPLPAALPERLREQLYGLPDGMGVLACFDGGGKVNYIGTFERV
HCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEHHHHH
YSEVSALLDSGKAPFDWCNTEEVRFFPALGSLHAYKIKAELVGRYHSGCYVSAKNLLKTF
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHCCCEEEEHHHHHHHH
TTVRFEKGSDGMLNAKTAALKNGVTDNPPTGLFSNKKAARRALSSWAETYGLCPASAGIL
HHEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
PDGYAEDEPCSVYVSGRCDKACGRSDEQVLAFAHKLPILDWGKMHEVEITETDPLTGEKV
CCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEE
VLHGMGGALEMDDGFWYFDKDLPDAFKAKFKTDRKNIKEIG
EEEECCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVASRWPLLEKVFLRFGMPVAVVDLESTGGNLYEDRVTEVALVKFEQGRVVRHEWLVNP
CEECCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHEEEEEECCCCEEEHHHCCCC
QKPIPQFVAGLTGISDGMVADAPVFAEIAGELFSVLKGCVLVAHNSRFDYTFLKHEFHRV
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHC
GIGFSSPALCSVQLSRCLYPQFYKHSLDSIIERLGIVVEDRHRAMADVSALCDYLEYSLS
CCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
EHGVEEWIRQCFRLMNPKPLPAALPERLREQLYGLPDGMGVLACFDGGGKVNYIGTFERV
HCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEHHHHH
YSEVSALLDSGKAPFDWCNTEEVRFFPALGSLHAYKIKAELVGRYHSGCYVSAKNLLKTF
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHCCCEEEEHHHHHHHH
TTVRFEKGSDGMLNAKTAALKNGVTDNPPTGLFSNKKAARRALSSWAETYGLCPASAGIL
HHEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
PDGYAEDEPCSVYVSGRCDKACGRSDEQVLAFAHKLPILDWGKMHEVEITETDPLTGEKV
CCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEE
VLHGMGGALEMDDGFWYFDKDLPDAFKAKFKTDRKNIKEIG
EEEECCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]