Click here to switch to the map view.

The map label for this gene is dnaZX [H]

Identifier: 161870312

GI number: 161870312

Start: 1367805

End: 1369925

Strand: Direct

Name: dnaZX [H]

Synonym: NMCC_1354

Alternate gene names: 161870312

Gene position: 1367805-1369925 (Clockwise)

Preceding gene: 161870311

Following gene: 161870313

Centisome position: 63.52

GC content: 57.99

Gene sequence:

>2121_bases
ATGGCCTATCAAGTTCTCGCCCGAAAATGGCGGCCCAAAACCTTTGCCGACTTAGTCGGTCAGGAACACGTCGTCAAAGC
CCTGCAAAATGCCTTGGACGAAGGCAGGCTGCACCACGCCTACCTGCTGACCGGTACGCGCGGCGTGGGCAAAACCACCA
TCGCCCGCATCCTTGCCAAAAGCCTCAACTGCGAAAACGCGCAACACGGCGAACCTTGCGGCGTGTGCCAAAGCTGCACC
CAAATCGATGCCGGACGCTATGTAGATTTATTGGAAATCGATGCCGCTTCCAACACAGGCATCGACAACATCCGCGAAGT
ATTGGAAAACGCCCAATACGCGCCGACCGCCGGCAAATACAAAGTCTATATCATCGACGAAGTGCATATGCTTTCCAAAA
GCGCGTTCAACGCTATGCTCAAAACGCTGGAAGAGCCACCCGAACACGTCAAATTCATCCTTGCCACGACCGATCCGCAC
AAAGTTCCCATTACCGTCTTGAGCCGCTGCCTGCAATTCGTCTTGCGCAATATGACTTCGCAGCAGGTTGCCGACCACCT
CGCCCACGTCCTCGACAGCGAAAAAATCGCCTACGAACCCCCCGCCCTGCAACTTTTGGGACGTGCCGCCGCCGGATCGA
TGCGCGATGCCTTGAGCCTGCTCGACCAAGCCATCGCCCTAGGTTCGGGCAAAGTTGCCGAAAACGATGTCCGCCAAATG
ATTGGCGCGGTTGACAAACAATACCTTTACGAACTGCTGACAGGCATCATCAACCAAGACGGCGCAGCCCTGACCGCCAA
AGCGCAGGAAATGGCGGCGTGTGCCGTCGGCTTTGACAACGCCTTGGGCGAACTGGCCATACTGCTGCAACAACTCGCCC
TGATACAGGCAGTGCCGAATGCCTTGGCGCACGACGACCCCGATTCCGATATTTTGCACCGCCTCGCCCAAACCATAAGC
GGCGAACAAATCCAGCTTTACTACCAAATCGCCGTCCACGGCAAACGCGACCTGGGCCTCGCCCCCGACGAATACGCCGG
CTTTATGATGACCCTGCTGCGTATGCTGGCGTTTGCGCCCTTGGCAGCAGCATCGTGTGATGCAAACGCCGTGATTGAAA
ATACCGAACTTCAATCCCCATCGGCACAAACCGCCGAAAAGGAAACCGCCGCAAAAAAGCCCCAACCGCACCCTGAAGCG
GAAACCACCCAAACGCCCGTTCAGACGGCATCCGCAGCGGCAATGCCGTCTGAAGGCAAAACTGCCGAACCCGTTTCCAA
TCAAGAAAACAACGATGTTCCGCCTTGGGAAGACGCGCCGGACGAAGCCCAAACCGCAGCCGGCACGGCGCAAACGTCGG
CAAAAAGCATTCAGACGGCATCCGAAGCCGAAACATCGCCTGACAATCAAGTTTCCAAGAACAAGGCAGCCGACAACGAA
ACCGAGACTTCCTTGTCCGAAGTGCCGTCTGAAAACCCCATTCAGGCAACACCGAATGATGAAGCCGTTGAAACGGAAGC
ATTTGCGCACGAAGCCCCTGCAGAACCTTTCTACGGTTACGGCTTTCCGGATAATGACTGCCCCCCGGAAGACGGCGCAG
AAATCCCGCCGCCGGATTGGGAACACGCCGCCCCTGCCGATGCGGAAGAAGAAAACAACGCCGACGAAGGCAGCAACGAC
GAAAACAACACGCCGTCCGCCCCGCCGCCCGAATTTTCCACCGAAAACTGGGCAGCCATCGTCCGGCATTTCGCCCGCAA
ACTCGGCGCGGCGCAAATGCCGGCGCAACACTCCGCGTGGACGGAATACCATCCCGACACCGGCCTGATGGTTTTGGCGA
TGACCGCCGAAGCCCGCGCCACCGCCGACAAAAAACGCCTCGACAAAATCCGCGACACCCTTGCCCAAGCCTACGGGCTG
CAACTCACCCTGCAAACCCAAGACTGGCGTGACGAAGCCGGCAGAGAAACCCCCGCGATGCAGGACAAGCGCGTCCAAGC
CGAAGACAGGCAAAAAGCACAAGCATTGCTCGAAGCCGACCCCGCCGCACAAAAAATCCTCCAAGCATTCGGCGCGCAAT
GGCAGCCCGAATCACTGGAATTGGCGGCAAACCGGCCATAA

Upstream 100 bases:

>100_bases
CAGTAAGCCGAAAGTGCTAGAATACGCCGCCCGAAGCCGCCGTTCAGACGGCATTCCGACGCACCGACAGAAACATCACG
ACCGAAACCAAGAGAAAAAT

Downstream 100 bases:

>100_bases
ACAGATATAATGCCGCCCGAACCCTTCGGACGGCATTGCCGTTTCCCTTATTCAATCAAAACAGACAGGAGTATTCAGTA
TGTTCGGAAAAGCCGGATTA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT
QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH
KVPITVLSRCLQFVLRNMTSQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM
IGAVDKQYLYELLTGIINQDGAALTAKAQEMAACAVGFDNALGELAILLQQLALIQAVPNALAHDDPDSDILHRLAQTIS
GEQIQLYYQIAVHGKRDLGLAPDEYAGFMMTLLRMLAFAPLAAASCDANAVIENTELQSPSAQTAEKETAAKKPQPHPEA
ETTQTPVQTASAAAMPSEGKTAEPVSNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETSPDNQVSKNKAADNE
TETSLSEVPSENPIQATPNDEAVETEAFAHEAPAEPFYGYGFPDNDCPPEDGAEIPPPDWEHAAPADAEEENNADEGSND
ENNTPSAPPPEFSTENWAAIVRHFARKLGAAQMPAQHSAWTEYHPDTGLMVLAMTAEARATADKKRLDKIRDTLAQAYGL
QLTLQTQDWRDEAGRETPAMQDKRVQAEDRQKAQALLEADPAAQKILQAFGAQWQPESLELAANRP

Sequences:

>Translated_706_residues
MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCT
QIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH
KVPITVLSRCLQFVLRNMTSQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM
IGAVDKQYLYELLTGIINQDGAALTAKAQEMAACAVGFDNALGELAILLQQLALIQAVPNALAHDDPDSDILHRLAQTIS
GEQIQLYYQIAVHGKRDLGLAPDEYAGFMMTLLRMLAFAPLAAASCDANAVIENTELQSPSAQTAEKETAAKKPQPHPEA
ETTQTPVQTASAAAMPSEGKTAEPVSNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETSPDNQVSKNKAADNE
TETSLSEVPSENPIQATPNDEAVETEAFAHEAPAEPFYGYGFPDNDCPPEDGAEIPPPDWEHAAPADAEEENNADEGSND
ENNTPSAPPPEFSTENWAAIVRHFARKLGAAQMPAQHSAWTEYHPDTGLMVLAMTAEARATADKKRLDKIRDTLAQAYGL
QLTLQTQDWRDEAGRETPAMQDKRVQAEDRQKAQALLEADPAAQKILQAFGAQWQPESLELAANRP
>Mature_705_residues
AYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQ
IDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHK
VPITVLSRCLQFVLRNMTSQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQMI
GAVDKQYLYELLTGIINQDGAALTAKAQEMAACAVGFDNALGELAILLQQLALIQAVPNALAHDDPDSDILHRLAQTISG
EQIQLYYQIAVHGKRDLGLAPDEYAGFMMTLLRMLAFAPLAAASCDANAVIENTELQSPSAQTAEKETAAKKPQPHPEAE
TTQTPVQTASAAAMPSEGKTAEPVSNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETSPDNQVSKNKAADNET
ETSLSEVPSENPIQATPNDEAVETEAFAHEAPAEPFYGYGFPDNDCPPEDGAEIPPPDWEHAAPADAEEENNADEGSNDE
NNTPSAPPPEFSTENWAAIVRHFARKLGAAQMPAQHSAWTEYHPDTGLMVLAMTAEARATADKKRLDKIRDTLAQAYGLQ
LTLQTQDWRDEAGRETPAMQDKRVQAEDRQKAQALLEADPAAQKILQAFGAQWQPESLELAANRP

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=337, Percent_Identity=27.299703264095, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI194306571, Length=340, Percent_Identity=27.0588235294118, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194306567, Length=340, Percent_Identity=27.0588235294118, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI31563534, Length=235, Percent_Identity=27.2340425531915, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI194306569, Length=256, Percent_Identity=27.734375, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=55.4016620498615, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1787119, Length=201, Percent_Identity=27.363184079602, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787341, Length=165, Percent_Identity=34.5454545454545, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71986063, Length=263, Percent_Identity=25.0950570342205, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17541988, Length=214, Percent_Identity=28.5046728971963, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17554730, Length=280, Percent_Identity=23.9285714285714, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324039, Length=217, Percent_Identity=27.1889400921659, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324478, Length=238, Percent_Identity=26.0504201680672, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322528, Length=278, Percent_Identity=24.1007194244604, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859927, Length=286, Percent_Identity=25.1748251748252, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17647857, Length=235, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921076, Length=298, Percent_Identity=23.489932885906, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 76372; Mature: 76240

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAK
CCHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
SLNCENAQHGEPCGVCQSCTQIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKY
HCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPITVLSRCLQFVLRNMTS
EEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
QQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IGAVDKQYLYELLTGIINQDGAALTAKAQEMAACAVGFDNALGELAILLQQLALIQAVPN
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAHDDPDSDILHRLAQTISGEQIQLYYQIAVHGKRDLGLAPDEYAGFMMTLLRMLAFAP
HHCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LAAASCDANAVIENTELQSPSAQTAEKETAAKKPQPHPEAETTQTPVQTASAAAMPSEGK
HHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
TAEPVSNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETSPDNQVSKNKAADNE
CCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCH
TETSLSEVPSENPIQATPNDEAVETEAFAHEAPAEPFYGYGFPDNDCPPEDGAEIPPPDW
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EHAAPADAEEENNADEGSNDENNTPSAPPPEFSTENWAAIVRHFARKLGAAQMPAQHSAW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHCCCCCCCCC
TEYHPDTGLMVLAMTAEARATADKKRLDKIRDTLAQAYGLQLTLQTQDWRDEAGRETPAM
CCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCC
QDKRVQAEDRQKAQALLEADPAAQKILQAFGAQWQPESLELAANRP
CHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAK
CHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
SLNCENAQHGEPCGVCQSCTQIDAGRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKY
HCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPITVLSRCLQFVLRNMTS
EEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
QQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IGAVDKQYLYELLTGIINQDGAALTAKAQEMAACAVGFDNALGELAILLQQLALIQAVPN
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAHDDPDSDILHRLAQTISGEQIQLYYQIAVHGKRDLGLAPDEYAGFMMTLLRMLAFAP
HHCCCCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
LAAASCDANAVIENTELQSPSAQTAEKETAAKKPQPHPEAETTQTPVQTASAAAMPSEGK
HHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
TAEPVSNQENNDVPPWEDAPDEAQTAAGTAQTSAKSIQTASEAETSPDNQVSKNKAADNE
CCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCH
TETSLSEVPSENPIQATPNDEAVETEAFAHEAPAEPFYGYGFPDNDCPPEDGAEIPPPDW
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EHAAPADAEEENNADEGSNDENNTPSAPPPEFSTENWAAIVRHFARKLGAAQMPAQHSAW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHCCCCCCCCC
TEYHPDTGLMVLAMTAEARATADKKRLDKIRDTLAQAYGLQLTLQTQDWRDEAGRETPAM
CCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCC
QDKRVQAEDRQKAQALLEADPAAQKILQAFGAQWQPESLELAANRP
CHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]