Click here to switch to the map view.

The map label for this gene is lutB [H]

Identifier: 161870306

GI number: 161870306

Start: 1361841

End: 1363295

Strand: Direct

Name: lutB [H]

Synonym: NMCC_1348

Alternate gene names: 161870306

Gene position: 1361841-1363295 (Clockwise)

Preceding gene: 161870305

Following gene: 161870311

Centisome position: 63.24

GC content: 54.02

Gene sequence:

>1455_bases
ATGACTACGCAAACCATCAAGTTCCACATGAAGCCGGAAACTTTCAAGCAAAACGCCGCAATTTCCCTTCAAGACAAGCC
TTTGCGCAAAAGCCTGCGTACCGCGATGGATATGCTGATGACCAAACGCAAAGCCGTTTTGACCGACGAAGAAGAGCTGC
AAAGCCTGCGCGATTTGTGCGAACACATCCGCCAGCGTTCCCTGTCCAAATTGCCCGCGCTGTTGGAGCAGTTGGAAGAA
AACCTGACCAAGTTGGGCGTGAAAGTACACTGGGCGGAAACCCCTGCCGAAGCCTGCCAAATTATCCACGACATCATCAC
AGCCAAAAACGGCAAGCTGATGGTCAAAGGTAAATCCATGGTCAGCGAGGAAATCGAGCTGAACCATTATCTTGAAGCAA
AAGGCATTAAAGCGGTAGAAAGCGACTTGGGCGAGTTCATCGTCCAAATGGCAGGCGAAAAACCGACCCATATTGTGATG
CCTGCTATCCACAAAACCAAAGAACAGGTTAGCGAACTGTTCCACCAAAACCTCGGTACGCCGCTGACAGACGATGTAGA
CCAACTGACCGGCTTCGCCCGTAAAGCACTGCGCGATATTTACAGCACTGCCGATGTCGGTTTGAGTGGCGTAAACTTCG
CCGTTGCTGAAACAGGTACGCTGTGTCTGGTGGAAAACGAAGGCAACGGTCGCTTGAGTACCACCGTACCGCCCGTGCAT
ATCGCTATTACCGGCATTGAAAAAGTGGTGGCGAAATTGTCCGACATCCCACCCTTGTACAGCCTGCTGCCGCGTTCTGC
CATTGGTCAGAACATTACCACTTATTTCAATATGATTACCGGCCCGCGCCGTAGCGAAGAGCTGGACGGTCCTCAAGAAA
TGCACTTGGTCCTGCTTGACAACGGTCGCAGCCAAGCCTATGCCGAAGACCAAATGCGCCGCACCTTGCAATGTATCCGT
TGCGGCGCGTGTATGAACCATTGCCCGGTTTATACCCGTATCGGTGGCGCGGCATATGGCACAACCTATCCCGGTCCGAT
TGGCGAGATTATTTCCCCGCACCTGTTAGGCTTGGATGCCACCCGCGACCTGCCGACCGCCTGTACCATGTGCGGTGCGT
GTGTGGAAGTCTGTCCGGTACGCATCCCGATTACCGAACAAATGCAGCGTTTGCGCGTTGAAGCGCAACGTTCGCCGACC
GAAACCGTGCCGCACCCCATCCGAGGGCAAGGCGCATCGCATACCTTCGGCGAACAAATGGCGTGGCGCACATTCAACGG
TATTTTCAGCGGCAGCAAAACCTACCGCGCCTTCGGTTGGGCAGCCACCAAGTTCCGCAACCTGACCCCGCGCAAACAGT
TGGGTTGGACGCAAAACCGCGTGCCGATGAAACCGGCGAAGAAAACCCTGCACGAACTAATGGCAGAAAAAATGCGCCAA
AAAGAACAGGCATAA

Upstream 100 bases:

>100_bases
TCCAACTGACGCTTGCTTACGGCGCGCACGGCCCGCGCGATTTGGTCATCCTCGCCATCCTGCCCGACCACATTTCCCCT
GCCGATTTGGAGGAAAACGC

Downstream 100 bases:

>100_bases
AAAGTTGTTCGCAAAAATGCCGTCTGAAACCCGAAACAGGGCTTCAGACGGCATTTGTATAGTGGATTAACAAAAATCAG
GACAAGGCGACGAAACCGAA

Product: iron-sulphur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTTQTIKFHMKPETFKQNAAISLQDKPLRKSLRTAMDMLMTKRKAVLTDEEELQSLRDLCEHIRQRSLSKLPALLEQLEE
NLTKLGVKVHWAETPAEACQIIHDIITAKNGKLMVKGKSMVSEEIELNHYLEAKGIKAVESDLGEFIVQMAGEKPTHIVM
PAIHKTKEQVSELFHQNLGTPLTDDVDQLTGFARKALRDIYSTADVGLSGVNFAVAETGTLCLVENEGNGRLSTTVPPVH
IAITGIEKVVAKLSDIPPLYSLLPRSAIGQNITTYFNMITGPRRSEELDGPQEMHLVLLDNGRSQAYAEDQMRRTLQCIR
CGACMNHCPVYTRIGGAAYGTTYPGPIGEIISPHLLGLDATRDLPTACTMCGACVEVCPVRIPITEQMQRLRVEAQRSPT
ETVPHPIRGQGASHTFGEQMAWRTFNGIFSGSKTYRAFGWAATKFRNLTPRKQLGWTQNRVPMKPAKKTLHELMAEKMRQ
KEQA

Sequences:

>Translated_484_residues
MTTQTIKFHMKPETFKQNAAISLQDKPLRKSLRTAMDMLMTKRKAVLTDEEELQSLRDLCEHIRQRSLSKLPALLEQLEE
NLTKLGVKVHWAETPAEACQIIHDIITAKNGKLMVKGKSMVSEEIELNHYLEAKGIKAVESDLGEFIVQMAGEKPTHIVM
PAIHKTKEQVSELFHQNLGTPLTDDVDQLTGFARKALRDIYSTADVGLSGVNFAVAETGTLCLVENEGNGRLSTTVPPVH
IAITGIEKVVAKLSDIPPLYSLLPRSAIGQNITTYFNMITGPRRSEELDGPQEMHLVLLDNGRSQAYAEDQMRRTLQCIR
CGACMNHCPVYTRIGGAAYGTTYPGPIGEIISPHLLGLDATRDLPTACTMCGACVEVCPVRIPITEQMQRLRVEAQRSPT
ETVPHPIRGQGASHTFGEQMAWRTFNGIFSGSKTYRAFGWAATKFRNLTPRKQLGWTQNRVPMKPAKKTLHELMAEKMRQ
KEQA
>Mature_483_residues
TTQTIKFHMKPETFKQNAAISLQDKPLRKSLRTAMDMLMTKRKAVLTDEEELQSLRDLCEHIRQRSLSKLPALLEQLEEN
LTKLGVKVHWAETPAEACQIIHDIITAKNGKLMVKGKSMVSEEIELNHYLEAKGIKAVESDLGEFIVQMAGEKPTHIVMP
AIHKTKEQVSELFHQNLGTPLTDDVDQLTGFARKALRDIYSTADVGLSGVNFAVAETGTLCLVENEGNGRLSTTVPPVHI
AITGIEKVVAKLSDIPPLYSLLPRSAIGQNITTYFNMITGPRRSEELDGPQEMHLVLLDNGRSQAYAEDQMRRTLQCIRC
GACMNHCPVYTRIGGAAYGTTYPGPIGEIISPHLLGLDATRDLPTACTMCGACVEVCPVRIPITEQMQRLRVEAQRSPTE
TVPHPIRGQGASHTFGEQMAWRTFNGIFSGSKTYRAFGWAATKFRNLTPRKQLGWTQNRVPMKPAKKTLHELMAEKMRQK
EQA

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=378, Percent_Identity=43.3862433862434, Blast_Score=350, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 53908; Mature: 53777

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQTIKFHMKPETFKQNAAISLQDKPLRKSLRTAMDMLMTKRKAVLTDEEELQSLRDLC
CCCCEEEEEECCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EHIRQRSLSKLPALLEQLEENLTKLGVKVHWAETPAEACQIIHDIITAKNGKLMVKGKSM
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEECHHH
VSEEIELNHYLEAKGIKAVESDLGEFIVQMAGEKPTHIVMPAIHKTKEQVSELFHQNLGT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHCCC
PLTDDVDQLTGFARKALRDIYSTADVGLSGVNFAVAETGTLCLVENEGNGRLSTTVPPVH
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCEEECCCCCEE
IAITGIEKVVAKLSDIPPLYSLLPRSAIGQNITTYFNMITGPRRSEELDGPQEMHLVLLD
EEEHHHHHHHHHHHCCCHHHHHCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
NGRSQAYAEDQMRRTLQCIRCGACMNHCPVYTRIGGAAYGTTYPGPIGEIISPHLLGLDA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHCCCHHCCCCC
TRDLPTACTMCGACVEVCPVRIPITEQMQRLRVEAQRSPTETVPHPIRGQGASHTFGEQM
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
AWRTFNGIFSGSKTYRAFGWAATKFRNLTPRKQLGWTQNRVPMKPAKKTLHELMAEKMRQ
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KEQA
HCCC
>Mature Secondary Structure 
TTQTIKFHMKPETFKQNAAISLQDKPLRKSLRTAMDMLMTKRKAVLTDEEELQSLRDLC
CCCEEEEEECCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EHIRQRSLSKLPALLEQLEENLTKLGVKVHWAETPAEACQIIHDIITAKNGKLMVKGKSM
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEECHHH
VSEEIELNHYLEAKGIKAVESDLGEFIVQMAGEKPTHIVMPAIHKTKEQVSELFHQNLGT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHCCC
PLTDDVDQLTGFARKALRDIYSTADVGLSGVNFAVAETGTLCLVENEGNGRLSTTVPPVH
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCCEEECCCCCEE
IAITGIEKVVAKLSDIPPLYSLLPRSAIGQNITTYFNMITGPRRSEELDGPQEMHLVLLD
EEEHHHHHHHHHHHCCCHHHHHCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
NGRSQAYAEDQMRRTLQCIRCGACMNHCPVYTRIGGAAYGTTYPGPIGEIISPHLLGLDA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHCCCHHCCCCC
TRDLPTACTMCGACVEVCPVRIPITEQMQRLRVEAQRSPTETVPHPIRGQGASHTFGEQM
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
AWRTFNGIFSGSKTYRAFGWAATKFRNLTPRKQLGWTQNRVPMKPAKKTLHELMAEKMRQ
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KEQA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA