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The map label for this gene is aroA [H]

Identifier: 161870300

GI number: 161870300

Start: 1355058

End: 1356257

Strand: Direct

Name: aroA [H]

Synonym: NMCC_1342

Alternate gene names: 161870300

Gene position: 1355058-1356257 (Clockwise)

Preceding gene: 161870298

Following gene: 161870304

Centisome position: 62.93

GC content: 57.0

Gene sequence:

>1200_bases
TTGTCCGACAATGCTTGCGAAATCCATTCCCTGCTCAAATCCGACGATACCGACCGTATGCTCGAAGCACTCGATAAACT
CGGCGTTGAAATCGAATATCTTGCCGAAGACCGTCTGAAAGTGCACGGCACAGGCGGACGCTTCCCCAACCGCACTGCCG
ATTTGTTTTTGGGCAACGCGGGCACGGCGTTCCGCCCGCTGACCGCCGCGCTTGCCGTTTTGGGCGGCGATTATCGCCTG
CACGGCGTTGCGCGTATGCACGAACGCCCCATCGGCGATTTGGCCGATGCACTGCGGATTGCCGGCGCCGATGTCGAATA
TCTCGGCAAGGAACACTATCCGCCGCTTCATATCGGCGAACGCCAAGACAACGGCGAGCGCGTGATTCCGATTAAAGGCA
ATGTATCCAGCCAGTTTCTGACCGCCCTTTTAATGGCGTTGCCGCTGACCGGGCAGGCGTTTGAAATCCGTATGGTCGGC
GAGTTAATTTCCAAGCCCTATATCGACATTACTTTAAAACTGATGGCGCAATTCGGCGTACAGGTTATCAATGAAGGCTA
CCGCGTCTTCAAAATTCCCGCCGATGCGCACTACCACGCGCCCGAACACTTGCACGTCGAAGGCGATGCCTCCAGCGCGT
CCTACTTCCTCGCAGCCGGTTTGATTGCCGCCACGCCCGTCCGCGTTACCGGTATCGGCGCAAACAGCATACAGGGCGAT
GTCGCCTTTGCCTGCGAGCTGGAAAAAATCGGTGCGGACGTGGTTTGGGGCGAAAACTTCGTCGAAGTCTCGCGCCCGAA
AGAACGTGCCGTCCAAGCCTTTGATTTGGATGCAAACCATATCCCCGATGCCGCCATGACCCTCGCCGTCGTCGCGCTTG
CTACAGGGCAAACCTGCACGCTTCGCAACATCGGTTCGTGGCGCGTCAAAGAGACCGACCGCATTGCCGCAATGGCGAAC
GAGTTGCGCAAACTCGGTGCAAAAGTCGCCGAAGAAGCCGAAGCAATTCACATCACCCCGCCCGAAACGCCGACACCCGA
CGCCGTCATCGACACTTACGACGACCACCGCATGGCAATGTGTTTCTCGCTGGTTTCGCTGTTGGGCGTACCCGTCGTCA
TCAACGATCCGAAATGCACCCATAAAACCTTCCCGACTTATTTCGACGTGTTCTCTTCACTGACCGAAACAACGGAATAA

Upstream 100 bases:

>100_bases
GACCGAATCCCTCCGCCTCCCTGCCGCCTCGCTCAAACCTTCCACTGTCGCCCTGCCCGGCTCCAAAAGCATCAGCAACC
GCACCCTGCTGCTTGCCGCC

Downstream 100 bases:

>100_bases
GGCGGCATTTTGCCGCGATTCCGGCGCGGCGCGGCGGGCGGCTCATTCTGTAAAGAAAGTATGTGCGCCGAGGTAGTTTT
TGGCGTAAAACGGTGTGGAG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSDNACEIHSLLKSDDTDRMLEALDKLGVEIEYLAEDRLKVHGTGGRFPNRTADLFLGNAGTAFRPLTAALAVLGGDYRL
HGVARMHERPIGDLADALRIAGADVEYLGKEHYPPLHIGERQDNGERVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVG
ELISKPYIDITLKLMAQFGVQVINEGYRVFKIPADAHYHAPEHLHVEGDASSASYFLAAGLIAATPVRVTGIGANSIQGD
VAFACELEKIGADVVWGENFVEVSRPKERAVQAFDLDANHIPDAAMTLAVVALATGQTCTLRNIGSWRVKETDRIAAMAN
ELRKLGAKVAEEAEAIHITPPETPTPDAVIDTYDDHRMAMCFSLVSLLGVPVVINDPKCTHKTFPTYFDVFSSLTETTE

Sequences:

>Translated_399_residues
MSDNACEIHSLLKSDDTDRMLEALDKLGVEIEYLAEDRLKVHGTGGRFPNRTADLFLGNAGTAFRPLTAALAVLGGDYRL
HGVARMHERPIGDLADALRIAGADVEYLGKEHYPPLHIGERQDNGERVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVG
ELISKPYIDITLKLMAQFGVQVINEGYRVFKIPADAHYHAPEHLHVEGDASSASYFLAAGLIAATPVRVTGIGANSIQGD
VAFACELEKIGADVVWGENFVEVSRPKERAVQAFDLDANHIPDAAMTLAVVALATGQTCTLRNIGSWRVKETDRIAAMAN
ELRKLGAKVAEEAEAIHITPPETPTPDAVIDTYDDHRMAMCFSLVSLLGVPVVINDPKCTHKTFPTYFDVFSSLTETTE
>Mature_398_residues
SDNACEIHSLLKSDDTDRMLEALDKLGVEIEYLAEDRLKVHGTGGRFPNRTADLFLGNAGTAFRPLTAALAVLGGDYRLH
GVARMHERPIGDLADALRIAGADVEYLGKEHYPPLHIGERQDNGERVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVGE
LISKPYIDITLKLMAQFGVQVINEGYRVFKIPADAHYHAPEHLHVEGDASSASYFLAAGLIAATPVRVTGIGANSIQGDV
AFACELEKIGADVVWGENFVEVSRPKERAVQAFDLDANHIPDAAMTLAVVALATGQTCTLRNIGSWRVKETDRIAAMANE
LRKLGAKVAEEAEAIHITPPETPTPDAVIDTYDDHRMAMCFSLVSLLGVPVVINDPKCTHKTFPTYFDVFSSLTETTE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=391, Percent_Identity=52.9411764705882, Blast_Score=380, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6320332, Length=436, Percent_Identity=35.7798165137615, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 43387; Mature: 43256

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNACEIHSLLKSDDTDRMLEALDKLGVEIEYLAEDRLKVHGTGGRFPNRTADLFLGNA
CCCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCCCCCCEEEECCC
GTAFRPLTAALAVLGGDYRLHGVARMHERPIGDLADALRIAGADVEYLGKEHYPPLHIGE
CCCHHHHHHHHHHHCCCEEEEHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
RQDNGERVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVGELISKPYIDITLKLMAQFGV
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHH
QVINEGYRVFKIPADAHYHAPEHLHVEGDASSASYFLAAGLIAATPVRVTGIGANSIQGD
HHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCC
VAFACELEKIGADVVWGENFVEVSRPKERAVQAFDLDANHIPDAAMTLAVVALATGQTCT
EEEEEEHHHCCCEEEECCCEEECCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCEEE
LRNIGSWRVKETDRIAAMANELRKLGAKVAEEAEAIHITPPETPTPDAVIDTYDDHRMAM
ECCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCHHHHH
CFSLVSLLGVPVVINDPKCTHKTFPTYFDVFSSLTETTE
HHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDNACEIHSLLKSDDTDRMLEALDKLGVEIEYLAEDRLKVHGTGGRFPNRTADLFLGNA
CCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCCCCCCEEEECCC
GTAFRPLTAALAVLGGDYRLHGVARMHERPIGDLADALRIAGADVEYLGKEHYPPLHIGE
CCCHHHHHHHHHHHCCCEEEEHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
RQDNGERVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVGELISKPYIDITLKLMAQFGV
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHH
QVINEGYRVFKIPADAHYHAPEHLHVEGDASSASYFLAAGLIAATPVRVTGIGANSIQGD
HHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCC
VAFACELEKIGADVVWGENFVEVSRPKERAVQAFDLDANHIPDAAMTLAVVALATGQTCT
EEEEEEHHHCCCEEEECCCEEECCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCEEE
LRNIGSWRVKETDRIAAMANELRKLGAKVAEEAEAIHITPPETPTPDAVIDTYDDHRMAM
ECCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCHHHHH
CFSLVSLLGVPVVINDPKCTHKTFPTYFDVFSSLTETTE
HHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA