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The map label for this gene is pgi [H]

Identifier: 161870262

GI number: 161870262

Start: 1304054

End: 1305700

Strand: Reverse

Name: pgi [H]

Synonym: NMCC_1303

Alternate gene names: 161870262

Gene position: 1305700-1304054 (Counterclockwise)

Preceding gene: 161870263

Following gene: 161870261

Centisome position: 60.63

GC content: 55.43

Gene sequence:

>1647_bases
ATGAAACACTTTCACGACTTACCCGCATGGTCGAAATTGTGGAACCACTTTGACGACAGCAAAACATTGCATATGCGCGA
AATGTTCGAGCAAGACCCGCAGCGTGCGGAACGCTACTGGCTGCAAGTCGGCGGACTGACGCTGGACTACTCCAAAAACC
GCATCAACGACGAAACCATGTCGCTTTTGTTCGAGCTTGCCCGAGAAGCAGGCGTGCCGGAGCGGATGCGGCAGATGTTC
CACGGCGAAAAAATCAATACCACCGAAAACCGCGCCGTCCTGCATGTCGCCCTTCGCAATCGCACCAATTCGCCGATTGT
GGTTGACGGTGAAGATGTGATGCCCAAAGTCAACCGCGTTTTGCAACGTATGGGCGAATTTGCACACGAAGTCCGCAGCG
GAAGCTGGCTGGGCTATACCAACCAAGTCATTACCGACGTTGTCAACATCGGCATCGGCGGATCGGATTTGGGTCCGCTG
ATGATGTGTACCGCGCTCAAACCTTTCGGTCATCCGCGCCTCAATATGCACTTCGTCTCCAACGTGGACGGCTCGCAACT
GCGCGACGTATTGTCCAAAGTCCACCCCGAAACCACGTTGTTCATCATCGCCTCCAAAACATTTACCACGCAGGAAACGC
TGACCAACGCGCTGACCGCGCGCGAATGGTTTTTGAATCATGCGGGCGACGAAGAAGCCGTTGCCAAACACTTCGCCGCC
GTTTCCACCAATCAAAAAGCCGTCGCCGAATTCGGCATCGACACCGCCAATATGTTTGAATTTTGGGATTGGGTCGGCGG
TCGGTACAGCCTGTGGTCCGCCATCGGATTGCCGATTATGCTGTATCTCGGCGAAGAAAACTTCATCGAAATGCTCAACG
GCGCGCACCTGATGGACCAACACTTCATCAACACACCGCTCGAGCGCAACCTGCCCGTCATTCTCGCCCTCATCGGCATC
TGGTATATCAACTACTACGGCGGCGGCAGCCACGTCATCGCGCCTTACGACCAACATTTGCACCGCCTGCCCAAATTCAT
CCAGCAGCTCGATATGGAAAGCAACGGCAAACAGGTTACGTTGGACGGCAAAGCAGTCGGACACGAAACCTCGCCGATTA
TCTGGGGCGAAACGGGCATTAACGGCCAGCACGCCTTCTTCCAACTGCTGCACCAAGGCACGCACATTACCCCCATCGAC
CTGATTGCCTCGCTTGAAAAACGCAGCAACCTGCCCGGACACCACGAAATCCTGCTTGCCAACGTCTTCGCCCAAGCAGA
AGCCTTTATGCGCGGCAAAACCCCCGACGAAGTCCGCGCCGAACTCAAAGCGCAGGGTATGGATGAGGCGCGCATCGAAG
AGCTGGTCCCGCACAAAACCTTCTCCGGCAACCGCCCGACCAACCTCATTCTCATGGACAAGGTCAACCCGCGCAATATG
GGCAGCCTGATTGCCATGTACGAACACAAAACCTTCGTACAAGGCATCATTTGGGGCATCAACAGCTTCGACCAGTGGGG
CGTGGAACTCGGCAAACAACTGGCTAAAACCATTTTGGGCGAACTGACCGGCGAAACCGGGCCGCAAAAGCACGACAGTT
CGACCGAACGCCTGATCAACCTCTACCTGCAGACCAACCGCAAATAA

Upstream 100 bases:

>100_bases
AATGCCGTCTGAAATGCCGAACAACGGTCGTCGGCGGCTTGCGGCAGTTTCCAGCAGCCTTTTCATCCCACAACAAAAAA
CCTCATTCAGGAGCATATAG

Downstream 100 bases:

>100_bases
AACCTGCGGAAAAATGCCGTCTGAACGCCGACCGTTTCAAACGGCATTTTTATCGAACAGGAAAACCGTCGGTAAACTTG
CAGAGCGTGTGCAATCCCGA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI 1; Phosphoglucose isomerase 1; PGI 1; Phosphohexose isomerase 1; PHI 1 [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MKHFHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVGGLTLDYSKNRINDETMSLLFELAREAGVPERMRQMF
HGEKINTTENRAVLHVALRNRTNSPIVVDGEDVMPKVNRVLQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPL
MMCTALKPFGHPRLNMHFVSNVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNALTAREWFLNHAGDEEAVAKHFAA
VSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIGLPIMLYLGEENFIEMLNGAHLMDQHFINTPLERNLPVILALIGI
WYINYYGGGSHVIAPYDQHLHRLPKFIQQLDMESNGKQVTLDGKAVGHETSPIIWGETGINGQHAFFQLLHQGTHITPID
LIASLEKRSNLPGHHEILLANVFAQAEAFMRGKTPDEVRAELKAQGMDEARIEELVPHKTFSGNRPTNLILMDKVNPRNM
GSLIAMYEHKTFVQGIIWGINSFDQWGVELGKQLAKTILGELTGETGPQKHDSSTERLINLYLQTNRK

Sequences:

>Translated_548_residues
MKHFHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVGGLTLDYSKNRINDETMSLLFELAREAGVPERMRQMF
HGEKINTTENRAVLHVALRNRTNSPIVVDGEDVMPKVNRVLQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPL
MMCTALKPFGHPRLNMHFVSNVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNALTAREWFLNHAGDEEAVAKHFAA
VSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIGLPIMLYLGEENFIEMLNGAHLMDQHFINTPLERNLPVILALIGI
WYINYYGGGSHVIAPYDQHLHRLPKFIQQLDMESNGKQVTLDGKAVGHETSPIIWGETGINGQHAFFQLLHQGTHITPID
LIASLEKRSNLPGHHEILLANVFAQAEAFMRGKTPDEVRAELKAQGMDEARIEELVPHKTFSGNRPTNLILMDKVNPRNM
GSLIAMYEHKTFVQGIIWGINSFDQWGVELGKQLAKTILGELTGETGPQKHDSSTERLINLYLQTNRK
>Mature_548_residues
MKHFHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVGGLTLDYSKNRINDETMSLLFELAREAGVPERMRQMF
HGEKINTTENRAVLHVALRNRTNSPIVVDGEDVMPKVNRVLQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPL
MMCTALKPFGHPRLNMHFVSNVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNALTAREWFLNHAGDEEAVAKHFAA
VSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIGLPIMLYLGEENFIEMLNGAHLMDQHFINTPLERNLPVILALIGI
WYINYYGGGSHVIAPYDQHLHRLPKFIQQLDMESNGKQVTLDGKAVGHETSPIIWGETGINGQHAFFQLLHQGTHITPID
LIASLEKRSNLPGHHEILLANVFAQAEAFMRGKTPDEVRAELKAQGMDEARIEELVPHKTFSGNRPTNLILMDKVNPRNM
GSLIAMYEHKTFVQGIIWGINSFDQWGVELGKQLAKTILGELTGETGPQKHDSSTERLINLYLQTNRK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=546, Percent_Identity=56.959706959707, Blast_Score=637, Evalue=0.0,
Organism=Homo sapiens, GI296080693, Length=546, Percent_Identity=53.1135531135531, Blast_Score=577, Evalue=1e-165,
Organism=Escherichia coli, GI1790457, Length=535, Percent_Identity=58.6915887850467, Blast_Score=653, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996708, Length=527, Percent_Identity=58.4440227703985, Blast_Score=627, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI71996703, Length=527, Percent_Identity=58.4440227703985, Blast_Score=626, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6319673, Length=546, Percent_Identity=52.5641025641026, Blast_Score=572, Evalue=1e-164,
Organism=Drosophila melanogaster, GI24651916, Length=548, Percent_Identity=56.9343065693431, Blast_Score=622, Evalue=1e-178,
Organism=Drosophila melanogaster, GI24651914, Length=548, Percent_Identity=56.9343065693431, Blast_Score=622, Evalue=1e-178,
Organism=Drosophila melanogaster, GI17737445, Length=548, Percent_Identity=56.9343065693431, Blast_Score=622, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 62091; Mature: 62091

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVGGLTLDYSKNRINDETM
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHCCCEEEECCCCCCCHHHH
SLLFELAREAGVPERMRQMFHGEKINTTENRAVLHVALRNRTNSPIVVDGEDVMPKVNRV
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHH
LQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPLMMCTALKPFGHPRLNMHFVS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEC
NVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNALTAREWFLNHAGDEEAVAKHFAA
CCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIGLPIMLYLGEENFIEMLNGAHLMDQ
HCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCHHHHHHHCCCHHHHH
HFINTPLERNLPVILALIGIWYINYYGGGSHVIAPYDQHLHRLPKFIQQLDMESNGKQVT
HHHCCCCCCCCHHHHHHHHHHHHEEECCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEE
LDGKAVGHETSPIIWGETGINGQHAFFQLLHQGTHITPIDLIASLEKRSNLPGHHEILLA
ECCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
NVFAQAEAFMRGKTPDEVRAELKAQGMDEARIEELVPHKTFSGNRPTNLILMDKVNPRNM
HHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCH
GSLIAMYEHKTFVQGIIWGINSFDQWGVELGKQLAKTILGELTGETGPQKHDSSTERLIN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LYLQTNRK
HHHHCCCC
>Mature Secondary Structure
MKHFHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVGGLTLDYSKNRINDETM
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHCCCEEEECCCCCCCHHHH
SLLFELAREAGVPERMRQMFHGEKINTTENRAVLHVALRNRTNSPIVVDGEDVMPKVNRV
HHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHH
LQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPLMMCTALKPFGHPRLNMHFVS
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEC
NVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNALTAREWFLNHAGDEEAVAKHFAA
CCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIGLPIMLYLGEENFIEMLNGAHLMDQ
HCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCHHHHHHHCCCHHHHH
HFINTPLERNLPVILALIGIWYINYYGGGSHVIAPYDQHLHRLPKFIQQLDMESNGKQVT
HHHCCCCCCCCHHHHHHHHHHHHEEECCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEE
LDGKAVGHETSPIIWGETGINGQHAFFQLLHQGTHITPIDLIASLEKRSNLPGHHEILLA
ECCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
NVFAQAEAFMRGKTPDEVRAELKAQGMDEARIEELVPHKTFSGNRPTNLILMDKVNPRNM
HHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCH
GSLIAMYEHKTFVQGIIWGINSFDQWGVELGKQLAKTILGELTGETGPQKHDSSTERLIN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LYLQTNRK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA