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The map label for this gene is argD [H]

Identifier: 161870242

GI number: 161870242

Start: 1284017

End: 1285210

Strand: Direct

Name: argD [H]

Synonym: NMCC_1283

Alternate gene names: 161870242

Gene position: 1284017-1285210 (Clockwise)

Preceding gene: 161870238

Following gene: 161870244

Centisome position: 59.63

GC content: 57.79

Gene sequence:

>1194_bases
ATGCAAAACTATCTGACCCCCAATTTCGCCTTTGCCCCGATGATTCCCGAACGTGCTTCAGGCAGCCGCGTTTGGGATAC
GGAAGGGCGTGAATATATTGATTTTTCAGGCGGTATCGCCGTCAATGCGCTGGGACACTGCCACCCTGCCCTTGTCGATG
CTTTAAACGCGCAGATGCACAAGCTGTGGCACATTTCCAATATCTATACGACGCGTCCGGCGCAGGAATTGGCGCAAAAA
TTGGTTGCAAACAGTTTTGCCGACAAGGTTTTTTTCTGCAACTCGGGCGCGGAAGCGAATGAGGCGGCGTTGAAGCTGGC
AAGGAAATATGCGCGCGACCGTTTCGGCGGAGGAAAAAGCGAAATCGTCGCCTGTATCAACAGTTTCCACGGACGCACGC
TGTTTACCGTGTCCGTCGGCGGCCAGCCGAAATACAGCAAGGGTTATGCACCCCTGCCGCAAGGCATTACGCACGTTCCG
TTCAACGATATTGCCGCGCTGGAAGCTGCCGTCGGCGAACAGACCTGCGCGGTCATCATCGAGCCGATACAGGGCGAAAG
CGGCATCCTGCCCGCCACTGCGGAATATTTGCAAACCGCGCGCCGTCTGTGCGACCGGCACAATGCGTTGTTGATTTTGG
ACGAAGTTCAAACCGGGATGGGGCATACGGGCAGGCTGTTTGCCTATGAACATTACGGCATTGTTCCCGATATTTTGAGT
TCGGCAAAAGCCTTGGGCTGCGGCTTTCCGATCGGCGCGATGCTGGCGACAGAAAAGATTGCCGCCGCCTTCCAACCGGG
CACGCATGGCTCGACTTTCGGCGGCAACCCGATGGCGTGCGCGGTCGGCAGCCGCGCCTTCGACATCATCAACGCGCCGG
AAACCTTGCACAACGTCCGCAGCCAGGGGCAGAAACTTCAGACGGCATTGCTGGATTTGGGCAGGAAAACAGGCTTGTTC
TCACAGGTTCGCGGGATGGGACTGCTGCTCGGCTGCGTGTTGGACGCGCCTTATCGCGGACGCGCATCCGAAATAACCGC
CGCCGCCTTGAAACACGGCGTGATGATTTTGGTTGCGGGTGCGGACGTATTGCGTTTCGCGCCTTCGCTGCTGTTGGACG
ATGAGGATACGGCGGAAGGTTTGCGGCGTTTGGAACACGTGCTGACGGAATTTGCCGCCGCAAACCGCCCCTAG

Upstream 100 bases:

>100_bases
CGGTTTATTTTTACCGCTGCCCGATATTGTCGGCAATTTCCCTTTATCTGCTTTGAAAAACGGTGCATAATCCCGAGCAA
AACCGCAATCAGGAGCAATT

Downstream 100 bases:

>100_bases
GCATCAAAAACAAAAAACCGCTTCGGAAACGTGGTTCAACGTTCCGAAGCGGTTTTGTTTGCCATCAGGACTCGAACACC
AATTCCGGTTCCCTGCCCTC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MQNYLTPNFAFAPMIPERASGSRVWDTEGREYIDFSGGIAVNALGHCHPALVDALNAQMHKLWHISNIYTTRPAQELAQK
LVANSFADKVFFCNSGAEANEAALKLARKYARDRFGGGKSEIVACINSFHGRTLFTVSVGGQPKYSKGYAPLPQGITHVP
FNDIAALEAAVGEQTCAVIIEPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQTGMGHTGRLFAYEHYGIVPDILS
SAKALGCGFPIGAMLATEKIAAAFQPGTHGSTFGGNPMACAVGSRAFDIINAPETLHNVRSQGQKLQTALLDLGRKTGLF
SQVRGMGLLLGCVLDAPYRGRASEITAAALKHGVMILVAGADVLRFAPSLLLDDEDTAEGLRRLEHVLTEFAAANRP

Sequences:

>Translated_397_residues
MQNYLTPNFAFAPMIPERASGSRVWDTEGREYIDFSGGIAVNALGHCHPALVDALNAQMHKLWHISNIYTTRPAQELAQK
LVANSFADKVFFCNSGAEANEAALKLARKYARDRFGGGKSEIVACINSFHGRTLFTVSVGGQPKYSKGYAPLPQGITHVP
FNDIAALEAAVGEQTCAVIIEPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQTGMGHTGRLFAYEHYGIVPDILS
SAKALGCGFPIGAMLATEKIAAAFQPGTHGSTFGGNPMACAVGSRAFDIINAPETLHNVRSQGQKLQTALLDLGRKTGLF
SQVRGMGLLLGCVLDAPYRGRASEITAAALKHGVMILVAGADVLRFAPSLLLDDEDTAEGLRRLEHVLTEFAAANRP
>Mature_397_residues
MQNYLTPNFAFAPMIPERASGSRVWDTEGREYIDFSGGIAVNALGHCHPALVDALNAQMHKLWHISNIYTTRPAQELAQK
LVANSFADKVFFCNSGAEANEAALKLARKYARDRFGGGKSEIVACINSFHGRTLFTVSVGGQPKYSKGYAPLPQGITHVP
FNDIAALEAAVGEQTCAVIIEPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQTGMGHTGRLFAYEHYGIVPDILS
SAKALGCGFPIGAMLATEKIAAAFQPGTHGSTFGGNPMACAVGSRAFDIINAPETLHNVRSQGQKLQTALLDLGRKTGLF
SQVRGMGLLLGCVLDAPYRGRASEITAAALKHGVMILVAGADVLRFAPSLLLDDEDTAEGLRRLEHVLTEFAAANRP

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=34.020618556701, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=34.4370860927152, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI13994255, Length=361, Percent_Identity=29.0858725761773, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=28.2352941176471, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=27.5700934579439, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=28.2051282051282, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=27.2941176470588, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI188536080, Length=437, Percent_Identity=24.7139588100687, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI38679950, Length=437, Percent_Identity=24.7139588100687, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI38679946, Length=437, Percent_Identity=24.7139588100687, Blast_Score=108, Evalue=9e-24,
Organism=Escherichia coli, GI1788044, Length=393, Percent_Identity=56.234096692112, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1789759, Length=390, Percent_Identity=56.4102564102564, Blast_Score=469, Evalue=1e-134,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=33.743842364532, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI145693181, Length=324, Percent_Identity=39.1975308641975, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=33.2506203473945, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1786991, Length=403, Percent_Identity=31.2655086848635, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786349, Length=333, Percent_Identity=29.1291291291291, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=392, Percent_Identity=33.1632653061224, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=405, Percent_Identity=30.8641975308642, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=27.1662763466042, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17541228, Length=420, Percent_Identity=25.2380952380952, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=31.4465408805031, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=386, Percent_Identity=37.3056994818653, Blast_Score=257, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6323470, Length=404, Percent_Identity=34.1584158415842, Blast_Score=214, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=315, Percent_Identity=29.2063492063492, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=414, Percent_Identity=23.9130434782609, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=33.8624338624339, Blast_Score=231, Evalue=7e-61,
Organism=Drosophila melanogaster, GI161085790, Length=453, Percent_Identity=32.0088300220751, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI28574759, Length=451, Percent_Identity=31.4855875831486, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=26.7942583732057, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=23.5981308411215, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=23.5981308411215, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=23.5981308411215, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42515; Mature: 42515

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNYLTPNFAFAPMIPERASGSRVWDTEGREYIDFSGGIAVNALGHCHPALVDALNAQMH
CCCCCCCCCEECCCCCCCCCCCEEECCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHH
KLWHISNIYTTRPAQELAQKLVANSFADKVFFCNSGAEANEAALKLARKYARDRFGGGKS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHH
EIVACINSFHGRTLFTVSVGGQPKYSKGYAPLPQGITHVPFNDIAALEAAVGEQTCAVII
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEE
EPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQTGMGHTGRLFAYEHYGIVPDILS
EECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCEEEEEECCCCHHHHHH
SAKALGCGFPIGAMLATEKIAAAFQPGTHGSTFGGNPMACAVGSRAFDIINAPETLHNVR
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHH
SQGQKLQTALLDLGRKTGLFSQVRGMGLLLGCVLDAPYRGRASEITAAALKHGVMILVAG
HHHHHHHHHHHHHCHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEEC
ADVLRFAPSLLLDDEDTAEGLRRLEHVLTEFAAANRP
CHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNYLTPNFAFAPMIPERASGSRVWDTEGREYIDFSGGIAVNALGHCHPALVDALNAQMH
CCCCCCCCCEECCCCCCCCCCCEEECCCCCEEEEECCCEEECCCCCCCHHHHHHHHHHHH
KLWHISNIYTTRPAQELAQKLVANSFADKVFFCNSGAEANEAALKLARKYARDRFGGGKS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHH
EIVACINSFHGRTLFTVSVGGQPKYSKGYAPLPQGITHVPFNDIAALEAAVGEQTCAVII
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEE
EPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQTGMGHTGRLFAYEHYGIVPDILS
EECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCEEEEEECCCCHHHHHH
SAKALGCGFPIGAMLATEKIAAAFQPGTHGSTFGGNPMACAVGSRAFDIINAPETLHNVR
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHH
SQGQKLQTALLDLGRKTGLFSQVRGMGLLLGCVLDAPYRGRASEITAAALKHGVMILVAG
HHHHHHHHHHHHHCHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEEC
ADVLRFAPSLLLDDEDTAEGLRRLEHVLTEFAAANRP
CHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]