Click here to switch to the map view.

The map label for this gene is rsmB [H]

Identifier: 161870221

GI number: 161870221

Start: 1261177

End: 1262436

Strand: Direct

Name: rsmB [H]

Synonym: NMCC_1262

Alternate gene names: 161870221

Gene position: 1261177-1262436 (Clockwise)

Preceding gene: 161870220

Following gene: 161870222

Centisome position: 58.57

GC content: 55.95

Gene sequence:

>1260_bases
ATGATGAACGCCGCACAACTCGACCATACCGCCAAAGTTTTGGCTGAAATGCTGACTTTCAAACAGCCTGCCGATGCCGT
CCTCTCCGCCTATTTCCGCGAACACAAAAAACTCGGCCGCCAAGACCGCCACGAAATCGCCGAAACTGCCTTTGCCGCGC
TGCGCCACTATCAAAAAATCAGTACCGCCCTGCGTCGTCCTCACGCGCAGCCGCGCAAAGCCGCACTCGCCGCACTGGTT
CTCGGCAGAAGCACCAACATCAGCCAAATCAAAGACCTGCTTGATGAAGAAGAAACAGAGTTCCTCGGCAATTTGAAAGC
CCGCAAAACCGAGTTTTCAGACGGTCTGAATACCGCCGCAGAATTGCCGCAATGGCTGGTCGAACAACTGCAACAGCATT
GGAACGAAGAAGAAATCCTCGCCTTCGGACGCAGCATCAACCAAGCCGCGCCGCTCGACATCCGCGTCAATACCTTGAAA
GGCAAACGCGATAAAGTGCTGCCATTGTTGCAAGCCGAAAGTGCCGATGCGGAGGCAACGCCTTATTCGCCTTGGGGCAT
CCGCCTGAAAAACAAAATCGCGCTTAACAAACACGAGCTGTTTTTGGACGGCACACTGGAAGTCCAAGACGAAGGCAGCC
AGCTGCTTGCTTTATTGGTGGGCGCAAAACGCGGCGAAATCATTGTCGATTTCTGTGCCGGCGCAGGCGGCAAAACCCTC
GCCATCGGCGCGCAAATGGCGAACAAAGGCAGAATCTACGCCTTCGACATCGCCGAAAAACGCCTTGCCAACCTCAAACC
GCGCATGACCCGTGCCGGACTGACCAACATCCACCCTGAACGCATCAGCAGTGAACACGATACCCGTATTGCCCGACTGG
CAGGCAAAGCCGACCGCGTTTTAGTGGATGCGCCCTGCTCCGGCTTAGGCACGCTGCGCCGCAATCCCGACCTCAAATAC
CGCCAATCCGCCGAGACCGTGGCCAACCTTTTGGAACAGCAACACAGCATCCTCGATGCCGCATCCAAACTGGTGAAACC
GCAAGGCCGCTTGGTGTACGCCACCTGCAGCGTGTTGCCGGAAGAAAACGAGCTGCAAGTCGAACGTTTCCTGTCCGAAC
ATCCCGAATTTGAACCCGTCAACTGCGCCGAACTGCTGCAAAGCCTGAAGGTTGATTTGGATACCGGAAAATACCTGCGC
CTCGATTCCGCCCGACACCAAACCGACGGCTTCTTCGCCGCCGTATTGCAACGCAAATAA

Upstream 100 bases:

>100_bases
ATTGCCGTTTTGGAATGTCGGCCGGACGGCTTTTGGCACGAAATCGAACGCATTATGAAGGCCGTCTGAAACCCTTTCCC
CACTTTAAGAGAACCCATTA

Downstream 100 bases:

>100_bases
ACCGGTTTGAACAAAATGCCGTCCGAACCCTTTTCAAAGCGTTCAGACGGCATTTCATCAATTATAGTGGATTAACAAAA
ATCAGTACGGCGTTGCCTCG

Product: SUN-family protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MMNAAQLDHTAKVLAEMLTFKQPADAVLSAYFREHKKLGRQDRHEIAETAFAALRHYQKISTALRRPHAQPRKAALAALV
LGRSTNISQIKDLLDEEETEFLGNLKARKTEFSDGLNTAAELPQWLVEQLQQHWNEEEILAFGRSINQAAPLDIRVNTLK
GKRDKVLPLLQAESADAEATPYSPWGIRLKNKIALNKHELFLDGTLEVQDEGSQLLALLVGAKRGEIIVDFCAGAGGKTL
AIGAQMANKGRIYAFDIAEKRLANLKPRMTRAGLTNIHPERISSEHDTRIARLAGKADRVLVDAPCSGLGTLRRNPDLKY
RQSAETVANLLEQQHSILDAASKLVKPQGRLVYATCSVLPEENELQVERFLSEHPEFEPVNCAELLQSLKVDLDTGKYLR
LDSARHQTDGFFAAVLQRK

Sequences:

>Translated_419_residues
MMNAAQLDHTAKVLAEMLTFKQPADAVLSAYFREHKKLGRQDRHEIAETAFAALRHYQKISTALRRPHAQPRKAALAALV
LGRSTNISQIKDLLDEEETEFLGNLKARKTEFSDGLNTAAELPQWLVEQLQQHWNEEEILAFGRSINQAAPLDIRVNTLK
GKRDKVLPLLQAESADAEATPYSPWGIRLKNKIALNKHELFLDGTLEVQDEGSQLLALLVGAKRGEIIVDFCAGAGGKTL
AIGAQMANKGRIYAFDIAEKRLANLKPRMTRAGLTNIHPERISSEHDTRIARLAGKADRVLVDAPCSGLGTLRRNPDLKY
RQSAETVANLLEQQHSILDAASKLVKPQGRLVYATCSVLPEENELQVERFLSEHPEFEPVNCAELLQSLKVDLDTGKYLR
LDSARHQTDGFFAAVLQRK
>Mature_419_residues
MMNAAQLDHTAKVLAEMLTFKQPADAVLSAYFREHKKLGRQDRHEIAETAFAALRHYQKISTALRRPHAQPRKAALAALV
LGRSTNISQIKDLLDEEETEFLGNLKARKTEFSDGLNTAAELPQWLVEQLQQHWNEEEILAFGRSINQAAPLDIRVNTLK
GKRDKVLPLLQAESADAEATPYSPWGIRLKNKIALNKHELFLDGTLEVQDEGSQLLALLVGAKRGEIIVDFCAGAGGKTL
AIGAQMANKGRIYAFDIAEKRLANLKPRMTRAGLTNIHPERISSEHDTRIARLAGKADRVLVDAPCSGLGTLRRNPDLKY
RQSAETVANLLEQQHSILDAASKLVKPQGRLVYATCSVLPEENELQVERFLSEHPEFEPVNCAELLQSLKVDLDTGKYLR
LDSARHQTDGFFAAVLQRK

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=256, Percent_Identity=28.90625, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI76150623, Length=256, Percent_Identity=28.90625, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI32698918, Length=201, Percent_Identity=31.3432835820896, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI270288816, Length=313, Percent_Identity=29.3929712460064, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI23199998, Length=313, Percent_Identity=29.3929712460064, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI270288818, Length=313, Percent_Identity=29.3929712460064, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI8922322, Length=313, Percent_Identity=29.3929712460064, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI40316918, Length=180, Percent_Identity=31.1111111111111, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI2367212, Length=366, Percent_Identity=30.8743169398907, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081985, Length=276, Percent_Identity=28.6231884057971, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17536757, Length=307, Percent_Identity=27.6872964169381, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534021, Length=232, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71998419, Length=232, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25143471, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=311, Percent_Identity=27.3311897106109, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI22024126, Length=256, Percent_Identity=28.90625, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21355201, Length=206, Percent_Identity=28.6407766990291, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356579, Length=242, Percent_Identity=27.6859504132231, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24668781, Length=177, Percent_Identity=29.3785310734463, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356513, Length=177, Percent_Identity=29.3785310734463, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46668; Mature: 46668

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNAAQLDHTAKVLAEMLTFKQPADAVLSAYFREHKKLGRQDRHEIAETAFAALRHYQKI
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
STALRRPHAQPRKAALAALVLGRSTNISQIKDLLDEEETEFLGNLKARKTEFSDGLNTAA
HHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHH
ELPQWLVEQLQQHWNEEEILAFGRSINQAAPLDIRVNTLKGKRDKVLPLLQAESADAEAT
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCC
PYSPWGIRLKNKIALNKHELFLDGTLEVQDEGSQLLALLVGAKRGEIIVDFCAGAGGKTL
CCCCCCEEEECEEEECCCEEEECCEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEE
AIGAQMANKGRIYAFDIAEKRLANLKPRMTRAGLTNIHPERISSEHDTRIARLAGKADRV
EEEHHHCCCCCEEEEEHHHHHHHCCCCHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCCEE
LVDAPCSGLGTLRRNPDLKYRQSAETVANLLEQQHSILDAASKLVKPQGRLVYATCSVLP
EEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
EENELQVERFLSEHPEFEPVNCAELLQSLKVDLDTGKYLRLDSARHQTDGFFAAVLQRK
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MMNAAQLDHTAKVLAEMLTFKQPADAVLSAYFREHKKLGRQDRHEIAETAFAALRHYQKI
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
STALRRPHAQPRKAALAALVLGRSTNISQIKDLLDEEETEFLGNLKARKTEFSDGLNTAA
HHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHH
ELPQWLVEQLQQHWNEEEILAFGRSINQAAPLDIRVNTLKGKRDKVLPLLQAESADAEAT
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCC
PYSPWGIRLKNKIALNKHELFLDGTLEVQDEGSQLLALLVGAKRGEIIVDFCAGAGGKTL
CCCCCCEEEECEEEECCCEEEECCEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEE
AIGAQMANKGRIYAFDIAEKRLANLKPRMTRAGLTNIHPERISSEHDTRIARLAGKADRV
EEEHHHCCCCCEEEEEHHHHHHHCCCCHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCCEE
LVDAPCSGLGTLRRNPDLKYRQSAETVANLLEQQHSILDAASKLVKPQGRLVYATCSVLP
EEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
EENELQVERFLSEHPEFEPVNCAELLQSLKVDLDTGKYLRLDSARHQTDGFFAAVLQRK
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]