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The map label for this gene is ftsK2 [H]

Identifier: 161870186

GI number: 161870186

Start: 1219584

End: 1221815

Strand: Reverse

Name: ftsK2 [H]

Synonym: NMCC_1226

Alternate gene names: 161870186

Gene position: 1221815-1219584 (Counterclockwise)

Preceding gene: 161870188

Following gene: 161870185

Centisome position: 56.74

GC content: 55.38

Gene sequence:

>2232_bases
ATGGGTTTGGCGGCAACCCTGTATTTGGCGATTTCCCTGATCAGTTTCGATATGGGCGATCCGTCTTGGTCGCACAGTTC
GCCGGTTGTGGAAGATGTCGCCAATTGGGGCGGACTGTTCGGCGCGTATGTTGCCGATGTCGGCTATTATCTTTTCGGCT
GGTCGTTCTGGTGGTGGATAGCGGCTGCCTGCGTCGTGCTGTATAAAAATTTCCGCCTGCACGCAAAACAGACGGAAAAC
GAGGCATACAACCACAAAATCGCTGCCGCCGCGCTGTTTGTCCTGACGGTCTTCAGCCCCGTCTTGGAGTATTTTGTGCT
GGGCGGAAAATATGCCGACTCCCTGCCTGTCGGAGCAGGCGGTATGGTCGGCATACGCGTCGGCGCAGTGTTTGCGTGGC
TGCTGGGGAAATCGGGCAGCCTGCTGATTATCTTGGTTGTTCTGCTGTTGTCGTTGTCCCTACTGGTGCAGATTTCATGG
CTGGAATTTTTGAACGGTGCAGGCAGGGCGGTTCAAAACCGCCTGAGTGCCTTATCCGGCAAGGTCATGGCTTTAGGAAA
ACGCCGGCCGAATACCAAAACAGACGGTGTCGATACCCAAAATACACGGCGCATGGTAAAAGAAGCCAAGAATATTACGG
CCAAACCCGTTGCCTTGCCCGAAGGCAGCAGCAGCAACCGCAAATCCGTCGCGGTTTCCGTCGCGCCGCCGCCCAAAATT
CAGGTTTCTCTGTTTGAAGATGACGAACCTCGGCAGGCGGGCGAATACCACAAGCCTACATTGAACCTATTGCGGATTCC
CGACAGCGAGCCCGTCAGCATCAATCCCGCCGAATTGGAGCGCACTGCCGAACTAATCGAATCCAAGCTGGCAGAATTCG
GCATCGGCGTACAAGTCGTATCCGCCACATCCGGCCCCGTCATCACGCGCTACGAAATCGAACCCGCGCAAGGTGTCAAA
GGCAGCCAAATTGTTGCCTTGTCGAAAGATTTGGCACGCTCTATGTCGCTGCAATCCGTGCGTATCGTCGAAACCATCGC
CGGGAAAAACACGATGGGCATCGAGTTGCCCAACGACAAACGCCAAGACGTGATGTTGAGCGAAATCTTGTCCTCGCCCG
TGTTTGCCGAAGCCAAATCCAAGCTGACCGTCGCGCTGGGCAAAGACATTGCCGGTACCCCCGTTGTCGGCGACTTGGCG
AAAATGCCGCACCTTTTGGTCGCCGGTATGACTGGTTCGGGCAAGTCCGTCGGCGTGAACGGCATGATTATGTCTATGCT
TTTCAAAGCTACGCCCGACGAAGTCCGCTTCATTATGATAGACCCGAAAATGCTCGAGTTGAGCATTTACGACGGCATTC
CGCACCTGCTCTGTCCCGTCGTGACCGATATGCGCGAAGCAGGGCAGGCGTTGAACTGGTGCGTCGCCGAAATGGAAAAA
CGCTACCGCCTGCTTTCCCACGCCGGTGTACGCAATCTGGAAGGCTTCAACCAAAAAGTCGAAGCCGCAAAAGCGGCAGG
CAAGCCTTTGCTTAATCCGTTCAGCCTGAACCCCGACGAGCCCGAGCCGCTGGAAAAACTGCCGTTGATTGTGGTCGTTA
TCGACGAACTTGCCGACCTGATGATGACGGAACGCAAAGCCGTCGAGCAGCAAATCGCCCGTCTCGCCCAAAAAGCGCGC
GCCGCCGGTATCCATATGATTGTCGCCACCCAACGTCCCAGTGTCGATGTCGTTACCGGCCTGATTAAAGCCAACATTCC
GACGCGTATGGCGTTTACCGTGCAAAGCAAAATCGACAGCCGTACCATCCTCGACCAAATGGGCGCGGACGAACTGCTCA
AATATGGCGATTCGCTGTTCCTTCAGCCCGGCAGTGCCGAACCGACCCGCCTGCAAGGCGCGTTTGTTTCAGACGACGAA
GTACATCAAGTCGTCAACTACGTCAAATCGCAAGCCCCAGCCGACTATATTGAAGGTCTGCTCAGCGGCGAGGCCGCGCT
GGAAACTGCCAATATCGTTAATCCGAATGCAGACAGCGACGAATTGTTCGATCAGGCAGTCGCCTATGTTTTGGAAAGCA
AAAAAACCTCCATTTCGTCTTTGCAGCGGCAGTTGCGTATCGGCTATAACCGCGCGGCAAACCTGATGGAGGCACTGGAA
AATGCGGGTGTCGTTTCTCCCGCCGACCTCAACGGCAGCCGTAAAATTTTGGCGCACAAGGACCATTTGTAG

Upstream 100 bases:

>100_bases
TTCCGAGCGGCTCAAGGCGGTCAAAGAGTTGCAGAAAACCGAAACCAAAAAGGCGCGTCCCGAACATGTCGTCAACCTTA
TCGGCGACGCACTGTGGCTG

Downstream 100 bases:

>100_bases
CCCGTATTGCAAAATGCCGTCTGAACGGCGGAATTCGCGTTTCAGACGGCATATTTATGTTTCAGGCGAAACATTGTGAT
ATACTTGCCAGCTAAAATTT

Product: cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MGLAATLYLAISLISFDMGDPSWSHSSPVVEDVANWGGLFGAYVADVGYYLFGWSFWWWIAAACVVLYKNFRLHAKQTEN
EAYNHKIAAAALFVLTVFSPVLEYFVLGGKYADSLPVGAGGMVGIRVGAVFAWLLGKSGSLLIILVVLLLSLSLLVQISW
LEFLNGAGRAVQNRLSALSGKVMALGKRRPNTKTDGVDTQNTRRMVKEAKNITAKPVALPEGSSSNRKSVAVSVAPPPKI
QVSLFEDDEPRQAGEYHKPTLNLLRIPDSEPVSINPAELERTAELIESKLAEFGIGVQVVSATSGPVITRYEIEPAQGVK
GSQIVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDKRQDVMLSEILSSPVFAEAKSKLTVALGKDIAGTPVVGDLA
KMPHLLVAGMTGSGKSVGVNGMIMSMLFKATPDEVRFIMIDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEK
RYRLLSHAGVRNLEGFNQKVEAAKAAGKPLLNPFSLNPDEPEPLEKLPLIVVVIDELADLMMTERKAVEQQIARLAQKAR
AAGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDSRTILDQMGADELLKYGDSLFLQPGSAEPTRLQGAFVSDDE
VHQVVNYVKSQAPADYIEGLLSGEAALETANIVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALE
NAGVVSPADLNGSRKILAHKDHL

Sequences:

>Translated_743_residues
MGLAATLYLAISLISFDMGDPSWSHSSPVVEDVANWGGLFGAYVADVGYYLFGWSFWWWIAAACVVLYKNFRLHAKQTEN
EAYNHKIAAAALFVLTVFSPVLEYFVLGGKYADSLPVGAGGMVGIRVGAVFAWLLGKSGSLLIILVVLLLSLSLLVQISW
LEFLNGAGRAVQNRLSALSGKVMALGKRRPNTKTDGVDTQNTRRMVKEAKNITAKPVALPEGSSSNRKSVAVSVAPPPKI
QVSLFEDDEPRQAGEYHKPTLNLLRIPDSEPVSINPAELERTAELIESKLAEFGIGVQVVSATSGPVITRYEIEPAQGVK
GSQIVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDKRQDVMLSEILSSPVFAEAKSKLTVALGKDIAGTPVVGDLA
KMPHLLVAGMTGSGKSVGVNGMIMSMLFKATPDEVRFIMIDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEK
RYRLLSHAGVRNLEGFNQKVEAAKAAGKPLLNPFSLNPDEPEPLEKLPLIVVVIDELADLMMTERKAVEQQIARLAQKAR
AAGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDSRTILDQMGADELLKYGDSLFLQPGSAEPTRLQGAFVSDDE
VHQVVNYVKSQAPADYIEGLLSGEAALETANIVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALE
NAGVVSPADLNGSRKILAHKDHL
>Mature_742_residues
GLAATLYLAISLISFDMGDPSWSHSSPVVEDVANWGGLFGAYVADVGYYLFGWSFWWWIAAACVVLYKNFRLHAKQTENE
AYNHKIAAAALFVLTVFSPVLEYFVLGGKYADSLPVGAGGMVGIRVGAVFAWLLGKSGSLLIILVVLLLSLSLLVQISWL
EFLNGAGRAVQNRLSALSGKVMALGKRRPNTKTDGVDTQNTRRMVKEAKNITAKPVALPEGSSSNRKSVAVSVAPPPKIQ
VSLFEDDEPRQAGEYHKPTLNLLRIPDSEPVSINPAELERTAELIESKLAEFGIGVQVVSATSGPVITRYEIEPAQGVKG
SQIVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDKRQDVMLSEILSSPVFAEAKSKLTVALGKDIAGTPVVGDLAK
MPHLLVAGMTGSGKSVGVNGMIMSMLFKATPDEVRFIMIDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEKR
YRLLSHAGVRNLEGFNQKVEAAKAAGKPLLNPFSLNPDEPEPLEKLPLIVVVIDELADLMMTERKAVEQQIARLAQKARA
AGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDSRTILDQMGADELLKYGDSLFLQPGSAEPTRLQGAFVSDDEV
HQVVNYVKSQAPADYIEGLLSGEAALETANIVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALEN
AGVVSPADLNGSRKILAHKDHL

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=492, Percent_Identity=57.520325203252, Blast_Score=539, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 80406; Mature: 80275

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLAATLYLAISLISFDMGDPSWSHSSPVVEDVANWGGLFGAYVADVGYYLFGWSFWWWI
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAACVVLYKNFRLHAKQTENEAYNHKIAAAALFVLTVFSPVLEYFVLGGKYADSLPVGAG
HHHHHHHHHHHHEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GMVGIRVGAVFAWLLGKSGSLLIILVVLLLSLSLLVQISWLEFLNGAGRAVQNRLSALSG
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
KVMALGKRRPNTKTDGVDTQNTRRMVKEAKNITAKPVALPEGSSSNRKSVAVSVAPPPKI
CCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEEECCCCCE
QVSLFEDDEPRQAGEYHKPTLNLLRIPDSEPVSINPAELERTAELIESKLAEFGIGVQVV
EEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
SATSGPVITRYEIEPAQGVKGSQIVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDK
ECCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHCHHHHHHHHHHCCCCCEEEECCCCC
RQDVMLSEILSSPVFAEAKSKLTVALGKDIAGTPVVGDLAKMPHLLVAGMTGSGKSVGVN
HHHHHHHHHHCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCH
GMIMSMLFKATPDEVRFIMIDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEK
HHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYRLLSHAGVRNLEGFNQKVEAAKAAGKPLLNPFSLNPDEPEPLEKLPLIVVVIDELADL
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEEEEHHHHHHH
MMTERKAVEQQIARLAQKARAAGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDS
HHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEEHHHCCH
RTILDQMGADELLKYGDSLFLQPGSAEPTRLQGAFVSDDEVHQVVNYVKSQAPADYIEGL
HHHHHHCCHHHHHHCCCCEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LSGEAALETANIVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALE
HCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHH
NAGVVSPADLNGSRKILAHKDHL
HCCCCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure 
GLAATLYLAISLISFDMGDPSWSHSSPVVEDVANWGGLFGAYVADVGYYLFGWSFWWWI
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAACVVLYKNFRLHAKQTENEAYNHKIAAAALFVLTVFSPVLEYFVLGGKYADSLPVGAG
HHHHHHHHHHHHEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GMVGIRVGAVFAWLLGKSGSLLIILVVLLLSLSLLVQISWLEFLNGAGRAVQNRLSALSG
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
KVMALGKRRPNTKTDGVDTQNTRRMVKEAKNITAKPVALPEGSSSNRKSVAVSVAPPPKI
CCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEEECCCCCE
QVSLFEDDEPRQAGEYHKPTLNLLRIPDSEPVSINPAELERTAELIESKLAEFGIGVQVV
EEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
SATSGPVITRYEIEPAQGVKGSQIVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDK
ECCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHCHHHHHHHHHHCCCCCEEEECCCCC
RQDVMLSEILSSPVFAEAKSKLTVALGKDIAGTPVVGDLAKMPHLLVAGMTGSGKSVGVN
HHHHHHHHHHCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCH
GMIMSMLFKATPDEVRFIMIDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEK
HHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYRLLSHAGVRNLEGFNQKVEAAKAAGKPLLNPFSLNPDEPEPLEKLPLIVVVIDELADL
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCEEEEEHHHHHHH
MMTERKAVEQQIARLAQKARAAGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDS
HHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEEHHHCCH
RTILDQMGADELLKYGDSLFLQPGSAEPTRLQGAFVSDDEVHQVVNYVKSQAPADYIEGL
HHHHHHCCHHHHHHCCCCEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LSGEAALETANIVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALE
HCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHH
NAGVVSPADLNGSRKILAHKDHL
HCCCCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]