Click here to switch to the map view.

The map label for this gene is fpr1 [H]

Identifier: 161870112

GI number: 161870112

Start: 1140282

End: 1141031

Strand: Direct

Name: fpr1 [H]

Synonym: NMCC_1151

Alternate gene names: 161870112

Gene position: 1140282-1141031 (Clockwise)

Preceding gene: 161870111

Following gene: 161870113

Centisome position: 52.95

GC content: 52.0

Gene sequence:

>750_bases
TTGTCCGTACACCACTGGACAGACGCATATTTTACCTTTACCTGCACCCGCGACGAATCGTTGCGCTTTGAAAACGGACA
GTTCGTTATGGTCGGATTGATGGTGGACGGCAAGCCGCTGATGCGTGCATACAGCGTCGCCTCCGCCAACTGGGAAGAAC
ACCTCGAATTTTTCAGCATTAAAGTCCAAGACGGCCCGCTGACCAGCCGCCTGCAACACCTCAAAGTCGGCGACGACGTG
TTAATCAGCAAAAAACCGACCGGAACCCTGGTTGCCGGCGACCTGAATCCGGGCAAACACCTTTACTTGTTGAGCACCGG
TACCGGCATCGCTCCTTTCTTGAGCATCACCAAAGACCCCGAAATTTACGAGCAATTTGAAAAAATCATCCTCGTACACG
GCGTGCGCTACAAAAAAGATTTGGCGTACTACGACCGCTTTACCAAAGAATTGCCCGAACACGAATACCTCGGTGACTTG
GTTAAAGAAAAACTGATTTACTACCCGATTGTTTCCCGAGAAGAATTCGAACACCACGGCCGCCTAACCGACCTGATGGT
GAGCGGCAAACTGTTTGAAGACATCGGCCTGCCCAAAATCAATCCTCAAGACGACCGCGCGATGCTGTGCGGCAGCCCCG
CGATGCTGAAAGACACCTGCAAAGTTTTGGACGATTTCGGACTAACCGTTTCTCCGAAAACAGGCGTGCGCGGCGATTAC
CTGATTGAGCGCGCGTTTGTGGATCAATAA

Upstream 100 bases:

>100_bases
CGGGCAGACATTTCCACTCTGCCGCACCTCCCGAACAAGCACTATCCATTTCTTTTACTGACAGGAAACCCAAATGGCAG
CATTCAATACCCAAAAAGTA

Downstream 100 bases:

>100_bases
GCTGCTTGAAAATGCCGTCTGAACGGCATCAGCGATAAAAAAACCCGAATCCTGCCAATCAGGATTCGGGGTTTTTATAG
TGGGTAAAAATTAGAAATAC

Product: ferredoxin--NADP reductase

Products: NA

Alternate protein names: FNR; Protein X [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSVHHWTDAYFTFTCTRDESLRFENGQFVMVGLMVDGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDDV
LISKKPTGTLVAGDLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDL
VKEKLIYYPIVSREEFEHHGRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDY
LIERAFVDQ

Sequences:

>Translated_249_residues
MSVHHWTDAYFTFTCTRDESLRFENGQFVMVGLMVDGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDDV
LISKKPTGTLVAGDLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDL
VKEKLIYYPIVSREEFEHHGRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDY
LIERAFVDQ
>Mature_248_residues
SVHHWTDAYFTFTCTRDESLRFENGQFVMVGLMVDGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDDVL
ISKKPTGTLVAGDLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLV
KEKLIYYPIVSREEFEHHGRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDYL
IERAFVDQ

Specific function: Transports Electrons Between Flavodoxin Or Ferredoxin And NADPH. Involved In The Reductive Activation Of Cobalamin- Independent Methionine Synthase, Pyruvate Formate Lyase And Anaerobic Ribonucleotide Reductase. Also Protects Against Superoxide Radicals

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=225, Percent_Identity=37.3333333333333, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 28341; Mature: 28210

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHHWTDAYFTFTCTRDESLRFENGQFVMVGLMVDGKPLMRAYSVASANWEEHLEFFSI
CCCCEEECEEEEEEEECCCCEEEECCCEEEEEEEECCHHHHHHHHHHCCCHHHCEEEEEE
KVQDGPLTSRLQHLKVGDDVLISKKPTGTLVAGDLNPGKHLYLLSTGTGIAPFLSITKDP
EEECCCHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCHHHEECCCCH
EIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLVKEKLIYYPIVSREEFEHHG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCHHHHHCC
RLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDY
CEEEEEECCCHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCCCCCHH
LIERAFVDQ
HHHHHHCCC
>Mature Secondary Structure 
SVHHWTDAYFTFTCTRDESLRFENGQFVMVGLMVDGKPLMRAYSVASANWEEHLEFFSI
CCCEEECEEEEEEEECCCCEEEECCCEEEEEEEECCHHHHHHHHHHCCCHHHCEEEEEE
KVQDGPLTSRLQHLKVGDDVLISKKPTGTLVAGDLNPGKHLYLLSTGTGIAPFLSITKDP
EEECCCHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCHHHEECCCCH
EIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLVKEKLIYYPIVSREEFEHHG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCHHHHHCC
RLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSPKTGVRGDY
CEEEEEECCCHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCCCCCHH
LIERAFVDQ
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7673160; 8034707; 9865948 [H]