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The map label for this gene is argB [H]

Identifier: 161869959

GI number: 161869959

Start: 994202

End: 995098

Strand: Direct

Name: argB [H]

Synonym: NMCC_0992

Alternate gene names: 161869959

Gene position: 994202-995098 (Clockwise)

Preceding gene: 161869956

Following gene: 161869965

Centisome position: 46.17

GC content: 54.07

Gene sequence:

>897_bases
ATGGCGTTTGAAAACATTATTTCCGCCGCCGACAAGGCGCGTATCCTTGCCGAAGCACTGCCTTACATCCGCCGGTTTTC
CGGTTCGGTCGTCGTCATCAAGTACGGCGGCAACGCCATGACCGAACCTGCCTTGAAAGAAGGGTTTGCCCGAGATGTCG
TGCTGCTGAAGCTGGTCGGCATTCATCCCGTCATCGTTCATGGCGGCGGGCCGCAGATCAATGCGATGCTTGAAAAAGTC
GGCAAAAAGGGTAAGTTTGTCCAAGGAATGCGCGTTACCGACAAAGAGGCGATGGATATTGTCGAAATGGTGTTGGGCGG
GCACGTCAATAAAGAAATCGTGTCGATGATTAACACATATGGCGGGCACGCGGTCGGCGTGAGCGGACGCGACGACCATT
TCATTAAGGCGAAGAAACTTTTGATCGATACGCCCGAACAGAATGGCGTAGACATCGGACAGGTCGGTACGGTGGAAAGC
ATCGATACAGGTTTGGTTAAAGGGCTGATAGAACGCGGCTGCATTCCCGTTGTCGCCCCCGTCGGCGTAGGTGAAAAAGG
CGAAGCGTTCAACATCAACGCCGATTTGGTAGCAGGCAAATTGGCGGAAGAATTGAACGCCGAAAAACTCTTGATGATGA
CGAATATCGCCGGTGTGATGGACAAAACGGGCAATCTGCTGACCAAACTCACGCCGAAACGGATTGATGAACTGATTGCC
GACGGCACGCTGTATGGCGGTATGCTGCCGAAAATCGCTTCTGCGGTCGAAGCCGCCGTCAACGGCGTGAAAGCCACGCA
CATCATCGACGGCAGGGTGCCCAACGCGCTTTTGCTGGAAATCTTTACCGATGCCGGTATCGGTTCGATGATTTTGGGCG
GTGGGGAAGATGCCTGA

Upstream 100 bases:

>100_bases
CTTCAACCTGCCCGAAGGTGTGCCGGATGCCGTCTGAAGATTGTTTCAGACGGCGTTTGGCGTTAACATAAGCCGAAATT
GTCAACAATAGGGAGCCGTT

Downstream 100 bases:

>100_bases
AGCAAAGTCGGAAAATGCCGGCTTTGGCGGAAAACCCGTTTGTCCGGTTTCTGTTTTTGGGGTTTCGGGCAATTTCCAAA
CCGTCATTCCTGAAAAAATA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MAFENIISAADKARILAEALPYIRRFSGSVVVIKYGGNAMTEPALKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKV
GKKGKFVQGMRVTDKEAMDIVEMVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVES
IDTGLVKGLIERGCIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKTGNLLTKLTPKRIDELIA
DGTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNALLLEIFTDAGIGSMILGGGEDA

Sequences:

>Translated_298_residues
MAFENIISAADKARILAEALPYIRRFSGSVVVIKYGGNAMTEPALKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKV
GKKGKFVQGMRVTDKEAMDIVEMVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVES
IDTGLVKGLIERGCIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKTGNLLTKLTPKRIDELIA
DGTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNALLLEIFTDAGIGSMILGGGEDA
>Mature_297_residues
AFENIISAADKARILAEALPYIRRFSGSVVVIKYGGNAMTEPALKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKVG
KKGKFVQGMRVTDKEAMDIVEMVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVESI
DTGLVKGLIERGCIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKTGNLLTKLTPKRIDELIAD
GTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNALLLEIFTDAGIGSMILGGGEDA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=288, Percent_Identity=30.5555555555556, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI145693208, Length=230, Percent_Identity=30, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=286, Percent_Identity=26.2237762237762, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 31299; Mature: 31168

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFENIISAADKARILAEALPYIRRFSGSVVVIKYGGNAMTEPALKEGFARDVVLLKLVG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
IHPVIVHGGGPQINAMLEKVGKKGKFVQGMRVTDKEAMDIVEMVLGGHVNKEIVSMINTY
CCEEEEECCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHC
GGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVESIDTGLVKGLIERGCIPVVAP
CCCEEECCCCCCCHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEE
VGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKTGNLLTKLTPKRIDELIA
CCCCCCCCEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHH
DGTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNALLLEIFTDAGIGSMILGGGEDA
CCCHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCC
>Mature Secondary Structure 
AFENIISAADKARILAEALPYIRRFSGSVVVIKYGGNAMTEPALKEGFARDVVLLKLVG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHC
IHPVIVHGGGPQINAMLEKVGKKGKFVQGMRVTDKEAMDIVEMVLGGHVNKEIVSMINTY
CCEEEEECCCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHC
GGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVESIDTGLVKGLIERGCIPVVAP
CCCEEECCCCCCCHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEE
VGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKTGNLLTKLTPKRIDELIA
CCCCCCCCEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHH
DGTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNALLLEIFTDAGIGSMILGGGEDA
CCCHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA