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The map label for this gene is dld [H]

Identifier: 161869908

GI number: 161869908

Start: 943563

End: 945101

Strand: Reverse

Name: dld [H]

Synonym: NMCC_0940

Alternate gene names: 161869908

Gene position: 945101-943563 (Counterclockwise)

Preceding gene: 161869912

Following gene: 161869907

Centisome position: 43.89

GC content: 55.04

Gene sequence:

>1539_bases
ATGTGGAAAATTCTGCAGGCCTGCGTCGAAGCGGACGTGATTGTGATTACGCAGGCGGCGAATACCGGTTTGACGGGTGG
CTCGACCCCCGACGGCAACGATTACGACCGCGACATCGTGATTGTGAACACCATGCGGATGAACATCATCCAAACCATCA
ACAACAACGAACAAGTCGTCTGCCTGCCCGGTTCGACCCTGAACCAGCTTGAATTGCTGCTGAAACCTTTGGGGCGCGAA
CCGCATTCGGTCATCGGCTCATCCTGTATCGGTGCGTCCGTCTTGGGCGGCGTGTGCAACAACTCCGGCGGCGCGTTGGT
ACAGCGCGGCCCGGCCTACACCGAAATGGCGTTGTTCGCCCAAATCAACGAAGAAGGCAGGTTGGAACTGGTCAACCACT
TGGGCATAGACTTGGGCGACACGCCCGAAGAAATCCTGACCAACCTGCAAGGTCATCATTATCAAAACAAAGACATCACG
CAAGATGCGGGCAAAGGGCACGACCACGCCTATTGCGAACACGTCCGCCAAGTGGACGAACCGACCGCCGCGCGTTTCAA
TGCCGACCCCGCCCGCCATTACGAAGCCTCGGGCTGCGCGGGCAAACTGATGGTTTTTGCCGTCCGTTTGGACACCTTCC
CGCAAGAAAAACAAACCGCCGTGTTCTACATCGGCACGAACGACATCAACGAGCTGACCGACATCCGCCGCGCCGCCTTG
GGCGAATTTGAAAGCCTGCCTGTTTCCGGCGAATACATCCACCGCCACGCTTTCGACATTGCCGACGTGTACGGCAAAGA
CACGTTTTACGTCATCAAAAAATTCGGTACGCACCAACTGCCGAAATTATTTGACTTGAAGGCGCGCGTGGACAGGTTCG
GCAAAAAAGCCAGCTTCCTGCCCAAACATTTTTCCGACAAGGCCATGCAGTTCGTCAGCAAATACCTGCCCGACCACCTG
CCCAAATCCATGCGCGATTACCGCGACAAATACGAACACCACCTGATTCTGAAAATGGGCGGGAAAGGCGTGGATGAGGC
GCGCGCGTTCTTAAAAGAATATTTTGCACACCACAGCGGCGCGTTTTTCGAGTGCAACGCCGAAGAAACCCAAGCCGCGA
TGCTGCACCGTTTCGCCGTCGCCTCCGCCGCCATCCGCTACCGCGCCGTGCATGATGACGAAGTGGAAGACTTGGTCGCG
CTCGACATCGCCCTGCGCCGCGACGATCGCGACTGGTTTGAAAAACTGCCGTCGGAAATCGACAATAAAATCATCCATAA
ACTCTACTATGGACATTTCATGTGCCACGTTTTCCATCAGGATTACATCATCAAAAAAGGCAACGACTGCATGGCGTTGG
AACACGAAATGCTGCATCTTTTAGACCAACGCGGCGCGCAATATCCCGCCGAACACAACGTCGGTCATTTGTATGAAGCC
AAGCCCGCGCTCAAACAGTTTTACCGCAAACTCGACCCGACCAACAGCTTCAACCCGGGTATCGGCAAAACCAGCAAAAA
GAAAAACTGGGCGGAATAA

Upstream 100 bases:

>100_bases
CATCATTACCGACCCCGCGAAAACCGAACAATACCGCCAAGGTTACCGCTTCGGCGAGGGTAAGGCGTTGGCGGTGGTTC
GCCCCGGAAGCATTCTGGAA

Downstream 100 bases:

>100_bases
GCGCGTCCGCTTTGAAGGCAGGCAATGCCGTCTGAAGGCAAAACGCCGTTCAGACGGCATTGTCGGGTTTGAAGTTCCCC
GTCGGGTAATCGCTTTCAAA

Product: D-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MWKILQACVEADVIVITQAANTGLTGGSTPDGNDYDRDIVIVNTMRMNIIQTINNNEQVVCLPGSTLNQLELLLKPLGRE
PHSVIGSSCIGASVLGGVCNNSGGALVQRGPAYTEMALFAQINEEGRLELVNHLGIDLGDTPEEILTNLQGHHYQNKDIT
QDAGKGHDHAYCEHVRQVDEPTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQEKQTAVFYIGTNDINELTDIRRAAL
GEFESLPVSGEYIHRHAFDIADVYGKDTFYVIKKFGTHQLPKLFDLKARVDRFGKKASFLPKHFSDKAMQFVSKYLPDHL
PKSMRDYRDKYEHHLILKMGGKGVDEARAFLKEYFAHHSGAFFECNAEETQAAMLHRFAVASAAIRYRAVHDDEVEDLVA
LDIALRRDDRDWFEKLPSEIDNKIIHKLYYGHFMCHVFHQDYIIKKGNDCMALEHEMLHLLDQRGAQYPAEHNVGHLYEA
KPALKQFYRKLDPTNSFNPGIGKTSKKKNWAE

Sequences:

>Translated_512_residues
MWKILQACVEADVIVITQAANTGLTGGSTPDGNDYDRDIVIVNTMRMNIIQTINNNEQVVCLPGSTLNQLELLLKPLGRE
PHSVIGSSCIGASVLGGVCNNSGGALVQRGPAYTEMALFAQINEEGRLELVNHLGIDLGDTPEEILTNLQGHHYQNKDIT
QDAGKGHDHAYCEHVRQVDEPTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQEKQTAVFYIGTNDINELTDIRRAAL
GEFESLPVSGEYIHRHAFDIADVYGKDTFYVIKKFGTHQLPKLFDLKARVDRFGKKASFLPKHFSDKAMQFVSKYLPDHL
PKSMRDYRDKYEHHLILKMGGKGVDEARAFLKEYFAHHSGAFFECNAEETQAAMLHRFAVASAAIRYRAVHDDEVEDLVA
LDIALRRDDRDWFEKLPSEIDNKIIHKLYYGHFMCHVFHQDYIIKKGNDCMALEHEMLHLLDQRGAQYPAEHNVGHLYEA
KPALKQFYRKLDPTNSFNPGIGKTSKKKNWAE
>Mature_512_residues
MWKILQACVEADVIVITQAANTGLTGGSTPDGNDYDRDIVIVNTMRMNIIQTINNNEQVVCLPGSTLNQLELLLKPLGRE
PHSVIGSSCIGASVLGGVCNNSGGALVQRGPAYTEMALFAQINEEGRLELVNHLGIDLGDTPEEILTNLQGHHYQNKDIT
QDAGKGHDHAYCEHVRQVDEPTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQEKQTAVFYIGTNDINELTDIRRAAL
GEFESLPVSGEYIHRHAFDIADVYGKDTFYVIKKFGTHQLPKLFDLKARVDRFGKKASFLPKHFSDKAMQFVSKYLPDHL
PKSMRDYRDKYEHHLILKMGGKGVDEARAFLKEYFAHHSGAFFECNAEETQAAMLHRFAVASAAIRYRAVHDDEVEDLVA
LDIALRRDDRDWFEKLPSEIDNKIIHKLYYGHFMCHVFHQDYIIKKGNDCMALEHEMLHLLDQRGAQYPAEHNVGHLYEA
KPALKQFYRKLDPTNSFNPGIGKTSKKKNWAE

Specific function: First component of the membrane-bound D-lactate oxidase, which is believed to play an important role in the energization of the active transport of a variety of sugars and amino acids [H]

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788454, Length=512, Percent_Identity=62.5, Blast_Score=688, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016172
- InterPro:   IPR016173
- InterPro:   IPR012256
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR015409
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF09330 Lact-deh-memb [H]

EC number: =1.1.1.28 [H]

Molecular weight: Translated: 57785; Mature: 57785

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00142 ZINC_PROTEASE ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKILQACVEADVIVITQAANTGLTGGSTPDGNDYDRDIVIVNTMRMNIIQTINNNEQVV
CHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEE
CLPGSTLNQLELLLKPLGREPHSVIGSSCIGASVLGGVCNNSGGALVQRGPAYTEMALFA
EECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHH
QINEEGRLELVNHLGIDLGDTPEEILTNLQGHHYQNKDITQDAGKGHDHAYCEHVRQVDE
HCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
PTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQEKQTAVFYIGTNDINELTDIRRAAL
CCHHCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
GEFESLPVSGEYIHRHAFDIADVYGKDTFYVIKKFGTHQLPKLFDLKARVDRFGKKASFL
CCHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHHHHHHCCHHHCC
PKHFSDKAMQFVSKYLPDHLPKSMRDYRDKYEHHLILKMGGKGVDEARAFLKEYFAHHSG
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHCCC
AFFECNAEETQAAMLHRFAVASAAIRYRAVHDDEVEDLVALDIALRRDDRDWFEKLPSEI
CEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
DNKIIHKLYYGHFMCHVFHQDYIIKKGNDCMALEHEMLHLLDQRGAQYPAEHNVGHLYEA
HHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHC
KPALKQFYRKLDPTNSFNPGIGKTSKKKNWAE
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MWKILQACVEADVIVITQAANTGLTGGSTPDGNDYDRDIVIVNTMRMNIIQTINNNEQVV
CHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEE
CLPGSTLNQLELLLKPLGREPHSVIGSSCIGASVLGGVCNNSGGALVQRGPAYTEMALFA
EECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHH
QINEEGRLELVNHLGIDLGDTPEEILTNLQGHHYQNKDITQDAGKGHDHAYCEHVRQVDE
HCCCCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
PTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQEKQTAVFYIGTNDINELTDIRRAAL
CCHHCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
GEFESLPVSGEYIHRHAFDIADVYGKDTFYVIKKFGTHQLPKLFDLKARVDRFGKKASFL
CCHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHHHHHHCCHHHCC
PKHFSDKAMQFVSKYLPDHLPKSMRDYRDKYEHHLILKMGGKGVDEARAFLKEYFAHHSG
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHCCC
AFFECNAEETQAAMLHRFAVASAAIRYRAVHDDEVEDLVALDIALRRDDRDWFEKLPSEI
CEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
DNKIIHKLYYGHFMCHVFHQDYIIKKGNDCMALEHEMLHLLDQRGAQYPAEHNVGHLYEA
HHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHC
KPALKQFYRKLDPTNSFNPGIGKTSKKKNWAE
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]