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The map label for this gene is ppnK [H]

Identifier: 161869751

GI number: 161869751

Start: 776051

End: 776941

Strand: Reverse

Name: ppnK [H]

Synonym: NMCC_0771

Alternate gene names: 161869751

Gene position: 776941-776051 (Counterclockwise)

Preceding gene: 161869752

Following gene: 161869750

Centisome position: 36.08

GC content: 56.68

Gene sequence:

>891_bases
ATGAACAGCCCTTTTCACAACATCGGCATCGTAACCCGCCCCAACACGCCCGACATCCAAGACACCGCACACACGCTGAT
TACCTTTTTGAAGCAGCACGGCTTTACCGTCTATCTCGACGAAGTCGGCATAAAGGAAGGCTGCATCTATACCCAAGACA
CCGTCGGCTGCCATATCGTCAACAAGACCGAACTGGGGCAATACTGCGACCTGGTCGCCGTTTTAGGCGGAGACGGCACC
TTTCTCTCCGTCGCCCGCGAAATCGCCCTGCGCGCCGTTCCGATTATCGGCATCAACCAAGGGCATTTGGGCTTCCTGAC
CCAAATTCCCCGCGAATATATGACGGACAAGCTATTGCCCGTTTTAGAAGGGAAATACCTTGCCGAAGAGCGCATCCTGA
TTGAGGCCGCACTCATCCGCGAAGGCAAAACCGCCGAACGCGCCATCGCCCTCAACGATGCCGTCCTCTCCCGTGGCGGC
GCCGGACAGATGATTGAGTTTGAAGTCTTCGTCAATCGGGAATTCGTCTATACCCAGCGTTCGGACGGGCTGATTGTCTC
CACCCCCACCGGATCGACCGCCTATTCGCTTGCCGCCGGCGGCCCCATCATGCAGGCAGGATTACACGCCTTCACACTCG
TACCCATCTGCCCGCAATCCATGACCAACCGCCCCATCGCCATTCCCGACACGTCTGAAATCGAAATCCTCGTTACCCAA
GGCGGCGACGCGCGCGTCCATTTCGACGGTCAAACCCATATCGACGTGCAAAACCTCGACCGCATCACCATCCGCCGCTA
CCGAAACCCCTTACGCATCCTACATCCGACCGACTACCAATATTTCAAAACCCTGCGCCAAAAACTGCACTGGGGCGAAC
AATTAGTCTAA

Upstream 100 bases:

>100_bases
GAAATAAGCAGACTGCGCGACGGCGTGGAACGCCTCAACGAACGCCTCGACCGGCTCGAACGCGACATTTGGATAGACTA
ACCTTCAGACGGCATCCGAC

Downstream 100 bases:

>100_bases
GCCGGCCTTTACCCGAAAGTATCCATGAATTCCAAAATTTCCTCCGACCATACAGAAGATGCCGTGCGCCTCTCCAAACG
CATGGCGCAACTGGGGCTTT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVGCHIVNKTELGQYCDLVAVLGGDGT
FLSVAREIALRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGG
AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVTQ
GGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQLV

Sequences:

>Translated_296_residues
MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVGCHIVNKTELGQYCDLVAVLGGDGT
FLSVAREIALRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGG
AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVTQ
GGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQLV
>Mature_296_residues
MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVGCHIVNKTELGQYCDLVAVLGGDGT
FLSVAREIALRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGG
AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVTQ
GGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQLV

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=306, Percent_Identity=27.7777777777778, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1788968, Length=296, Percent_Identity=39.527027027027, Blast_Score=215, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6320794, Length=245, Percent_Identity=29.3877551020408, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322509, Length=260, Percent_Identity=28.4615384615385, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325068, Length=248, Percent_Identity=28.6290322580645, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=30.8300395256917, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28573832, Length=253, Percent_Identity=30.8300395256917, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573830, Length=281, Percent_Identity=29.1814946619217, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573826, Length=253, Percent_Identity=30.8300395256917, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI161077047, Length=293, Percent_Identity=28.6689419795222, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=26.2589928057554, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=26.2589928057554, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=26.2589928057554, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=26.2589928057554, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=26.2589928057554, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32853; Mature: 32853

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVGCHIV
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCEEEE
NKTELGQYCDLVAVLGGDGTFLSVAREIALRAVPIIGINQGHLGFLTQIPREYMTDKLLP
CHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCHHHHHHHHHH
VLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGGAGQMIEFEVFVNREFVYTQR
HHCCCHHHHHHHHEEEEHHCCCCCHHHEEEECHHHHCCCCCCCEEEEEEEECCEEEEEEC
SDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVTQ
CCCEEEECCCCCCEEEECCCCHHHHHCCCEEEEEEECCHHHCCCCEECCCCCCEEEEEEC
GGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQLV
CCCEEEEECCCEEEEHHHCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVGCHIV
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCEEEE
NKTELGQYCDLVAVLGGDGTFLSVAREIALRAVPIIGINQGHLGFLTQIPREYMTDKLLP
CHHHHHHHHEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHCCHHHHHHHHHH
VLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGGAGQMIEFEVFVNREFVYTQR
HHCCCHHHHHHHHEEEEHHCCCCCHHHEEEECHHHHCCCCCCCEEEEEEEECCEEEEEEC
SDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVTQ
CCCEEEECCCCCCEEEECCCCHHHHHCCCEEEEEEECCHHHCCCCEECCCCCCEEEEEEC
GGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQLV
CCCEEEEECCCEEEEHHHCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA