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The map label for this gene is ftsJ [H]

Identifier: 161869743

GI number: 161869743

Start: 769963

End: 770583

Strand: Reverse

Name: ftsJ [H]

Synonym: NMCC_0763

Alternate gene names: 161869743

Gene position: 770583-769963 (Counterclockwise)

Preceding gene: 161869747

Following gene: 161869742

Centisome position: 35.78

GC content: 53.62

Gene sequence:

>621_bases
ATGGCTGTACGTTCCAAATCCTCAAAAGCGTGGCTGCACGAACACGTCAACGACCACTACGTCCATATGGCGCAAAAAGA
CGGCTACCGCGCCCGTGCCGCATACAAACTTTTGGAAATCAACGAAAAAGACAAATTAATCAAACCCGGCACGGTACTTG
CCGACTTGGGCAGCGCACCGGGAAGCTGGTCGCAGGTTGCCGCCAAGCTGACGGGTACTTCCGGCGCGGTATTCGCTTTG
GACATCCTACCCATGGAAGCCATAGGGGGCGTCTCCTTCATTCAGGGCGACTTCCGCGAGAACGACGTACTGGCACAATT
TGAAACCTTGTTGGACAACCGCCCGCTCGACCTTGTAATTTGCGATATGGCGCCCAATATGTCGGGAAACGCCGTAAGCG
ATCAGGCACGCAGCTTTTATCTGTGCGAACTGGCTTTAGACTTCGCCTCGCAACACCTGAAAACCGGCGGCAGCTTTTTG
GTCAAAGTCTTTCAGGGTGCAGGCTATCAGGAATACATGGCAGCCATGCGCGAAATTTTCGGCACGGTGCAGACGCGCAA
ACCCGAAGCCTCGCGCAATCGCTCCAGTGAGATTTATTTATTGGGCAAAAATAAACGCTGA

Upstream 100 bases:

>100_bases
GCTTGAATAAAAAGAATAATGCGGCATTGTACGCGATTTGGCACGACATCGGCAAAATTAACGTACAATACGCGGTTTCC
ATTCCGACCCGCGAACCACT

Downstream 100 bases:

>100_bases
CAATACAGACGGCGTGCTTTACAATCATTTCCGTTTTACACCTCAATTATGGAGCCTTGCTAAGTGGGGAACACCTTTAA
ATCAATCCTTGTCTGGGTCG

Product: cell division protein

Products: NA

Alternate protein names: 23S rRNA Um2552 methyltransferase; rRNA (uridine-2'-O-)-methyltransferase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MAVRSKSSKAWLHEHVNDHYVHMAQKDGYRARAAYKLLEINEKDKLIKPGTVLADLGSAPGSWSQVAAKLTGTSGAVFAL
DILPMEAIGGVSFIQGDFRENDVLAQFETLLDNRPLDLVICDMAPNMSGNAVSDQARSFYLCELALDFASQHLKTGGSFL
VKVFQGAGYQEYMAAMREIFGTVQTRKPEASRNRSSEIYLLGKNKR

Sequences:

>Translated_206_residues
MAVRSKSSKAWLHEHVNDHYVHMAQKDGYRARAAYKLLEINEKDKLIKPGTVLADLGSAPGSWSQVAAKLTGTSGAVFAL
DILPMEAIGGVSFIQGDFRENDVLAQFETLLDNRPLDLVICDMAPNMSGNAVSDQARSFYLCELALDFASQHLKTGGSFL
VKVFQGAGYQEYMAAMREIFGTVQTRKPEASRNRSSEIYLLGKNKR
>Mature_205_residues
AVRSKSSKAWLHEHVNDHYVHMAQKDGYRARAAYKLLEINEKDKLIKPGTVLADLGSAPGSWSQVAAKLTGTSGAVFALD
ILPMEAIGGVSFIQGDFRENDVLAQFETLLDNRPLDLVICDMAPNMSGNAVSDQARSFYLCELALDFASQHLKTGGSFLV
KVFQGAGYQEYMAAMREIFGTVQTRKPEASRNRSSEIYLLGKNKR

Specific function: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit [H]

COG id: COG0293

COG function: function code J; 23S rRNA methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family [H]

Homologues:

Organism=Homo sapiens, GI7019377, Length=207, Percent_Identity=34.2995169082126, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI194097365, Length=185, Percent_Identity=34.0540540540541, Blast_Score=127, Evalue=6e-30,
Organism=Homo sapiens, GI29029591, Length=184, Percent_Identity=36.4130434782609, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI29029589, Length=184, Percent_Identity=36.4130434782609, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI7110661, Length=184, Percent_Identity=36.4130434782609, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1789569, Length=203, Percent_Identity=47.7832512315271, Blast_Score=207, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17553474, Length=210, Percent_Identity=33.8095238095238, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71987550, Length=184, Percent_Identity=34.2391304347826, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71987561, Length=184, Percent_Identity=34.2391304347826, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17553860, Length=184, Percent_Identity=34.2391304347826, Blast_Score=117, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17554650, Length=187, Percent_Identity=34.7593582887701, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319796, Length=202, Percent_Identity=33.6633663366337, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319535, Length=199, Percent_Identity=32.6633165829146, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321302, Length=109, Percent_Identity=35.7798165137615, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356387, Length=210, Percent_Identity=35.2380952380952, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI18859957, Length=184, Percent_Identity=32.0652173913043, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24647580, Length=194, Percent_Identity=32.4742268041237, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24648639, Length=195, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015507
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: =2.1.1.166 [H]

Molecular weight: Translated: 22721; Mature: 22590

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRSKSSKAWLHEHVNDHYVHMAQKDGYRARAAYKLLEINEKDKLIKPGTVLADLGSAP
CCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHEEEECCCCCEECCCCCEEECCCCC
GSWSQVAAKLTGTSGAVFALDILPMEAIGGVSFIQGDFRENDVLAQFETLLDNRPLDLVI
CCHHHHHHHHCCCCCCEEEEEEECHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEE
CDMAPNMSGNAVSDQARSFYLCELALDFASQHLKTGGSFLVKVFQGAGYQEYMAAMREIF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
GTVQTRKPEASRNRSSEIYLLGKNKR
HHHHCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
AVRSKSSKAWLHEHVNDHYVHMAQKDGYRARAAYKLLEINEKDKLIKPGTVLADLGSAP
CCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHEEEECCCCCEECCCCCEEECCCCC
GSWSQVAAKLTGTSGAVFALDILPMEAIGGVSFIQGDFRENDVLAQFETLLDNRPLDLVI
CCHHHHHHHHCCCCCCEEEEEEECHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEE
CDMAPNMSGNAVSDQARSFYLCELALDFASQHLKTGGSFLVKVFQGAGYQEYMAAMREIF
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
GTVQTRKPEASRNRSSEIYLLGKNKR
HHHHCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA