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The map label for this gene is atpA [H]

Identifier: 161869277

GI number: 161869277

Start: 288582

End: 290129

Strand: Direct

Name: atpA [H]

Synonym: NMCC_0282

Alternate gene names: 161869277

Gene position: 288582-290129 (Clockwise)

Preceding gene: 161869276

Following gene: 161869278

Centisome position: 13.4

GC content: 50.9

Gene sequence:

>1548_bases
ATGCAGCTTAATCCTGCTGAAATTAGCGATTTGATTAAAGCCAAGATCGAAAATCTGTCTGTAAATGCCGAAGTGCGTAC
TCGTGGTACGGTGATTTCGGTAACTGACGGTATCGTTCGCATCCATGGTTTGTCAGATGCAATGCAAGGTGAGATGCTCG
AATTCCCGGGTAACACTTTCGGCTTGGCGATGAACCTGGAGCGCGACTCCGTCGGCGCCGTAGTGTTGGGCGAGTACGAA
CATATTAAAGAAGGCGACACGGTTACCTGTACCGGTCGTATCTTGGAAGTGCCGGTCGGACGCGAACTGGTCGGACGCGT
CGTTGATGCATTGGGTCGGCCTATCGACGGCAAAGGCCCGATTAATACAACTTTGACCGCCCCTATCGAAAAAATCGCAC
CGGGCGTGATTGCGCGCAAATCGGTTGACCAGCCGATGCAAACCGGTCTGAAGGCGATTGACTCTATGGTTCCTGTCGGT
CGCGGTCAGCGTGAGTTGATTATTGGCGACCGTCAAACCGGTAAAACGGCCGTAGCATTGGATGCCATCGTCAACCAAAA
AGGTACGGGTGTTATCTGTATCTATGTCGCTATCGGTCAAAAAGCATCTTCTATTGCCAACGTGGTCCGCAAATTGGAAG
AGCATGGCGCGATGGAGCATACCATCGTGGTTGCTGCAACTGCATCTGAAGCGGCGGCATTGCAATATATCGCACCTTAC
TCCGGTTGTACGATGGGTGAATTCTTCCGCGATCGTGGCGAAGATGCCTTGATTGTTTATGACGATTTGTCCAAACAGGC
TGTGGCTTACCGTCAAATTTCCCTGCTTTTGCGCCGTCCGCCCGGCCGCGAAGCCTATCCCGGCGATGTGTTCTACCTGC
ACTCCCGTCTGTTGGAACGTGCAGCACGTGTCAATGAACACGAAGTGGAGAAATTGACCAACGGCGAAGTAAAAGGCAAA
ACCGGTTCTCTGACCGCGTTGCCGATTATCGAAACCCAAGCGGGCGACGTATCTGCTTTCGTTCCGACTAACGTCATTTC
GATTACCGACGGTCAGATTTTCTTGGAAACCGACCTCTTCAACGCCGGTATCCGTCCTGCAATCAATGCCGGTATTTCCG
TATCCCGCGTAGGCGGTGCTGCACAAACCAAAGTGATTAAAAAGCTGGGTGGCGGTATCCGTTTGGCGTTGGCGCAATAT
CGTGAATTGGCGGCGTTCTCGCAATTTGCATCCGATTTGGATGAAGCTACGCGCAAACAATTGGAGCATGGCGAAGTCGT
AACCGAACTGATGAAACAGAAACAGTTCAGTACGTTGAATACGGCTGAAATGGCTTTGACCCTTTGGGCAATCAACAACG
GTTCGTATTCTGATGTTCCGGTTGCCAAAGCTCTGGCTTTTGAATCTGAATTTTTGAGCTTTGTCCGTACCCAACATCCG
GAAGTTTTGGAAGCCGTCAATGCTTCAGGTGCAATGTCCGACGAGAGCGAGAAAACGCTTGAAGCAGCCATGAAATCCTT
CAAATCTTCTTACGCCTATCAGGCATAA

Upstream 100 bases:

>100_bases
GGCGGCATAAAAGTTGAAGTGGGTGATCAGGTTTTGGATTTGTCTGTACGAGGCAAATTGAGTGCCTTGTACACGACTAT
GACGAATTAGGAGAGTTTTC

Downstream 100 bases:

>100_bases
GGCTTGAAGTGAAAGGAGTCTGAAATGGCAGTAGGAAAAGAGATTCTCACCAAAATCCGCAGTGTTCAGAATACCCAAAA
GATCACTAAAGCGATGCAGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MQLNPAEISDLIKAKIENLSVNAEVRTRGTVISVTDGIVRIHGLSDAMQGEMLEFPGNTFGLAMNLERDSVGAVVLGEYE
HIKEGDTVTCTGRILEVPVGRELVGRVVDALGRPIDGKGPINTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVG
RGQRELIIGDRQTGKTAVALDAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAMEHTIVVAATASEAAALQYIAPY
SGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEHEVEKLTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGIRLALAQY
RELAAFSQFASDLDEATRKQLEHGEVVTELMKQKQFSTLNTAEMALTLWAINNGSYSDVPVAKALAFESEFLSFVRTQHP
EVLEAVNASGAMSDESEKTLEAAMKSFKSSYAYQA

Sequences:

>Translated_515_residues
MQLNPAEISDLIKAKIENLSVNAEVRTRGTVISVTDGIVRIHGLSDAMQGEMLEFPGNTFGLAMNLERDSVGAVVLGEYE
HIKEGDTVTCTGRILEVPVGRELVGRVVDALGRPIDGKGPINTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVG
RGQRELIIGDRQTGKTAVALDAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAMEHTIVVAATASEAAALQYIAPY
SGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEHEVEKLTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGIRLALAQY
RELAAFSQFASDLDEATRKQLEHGEVVTELMKQKQFSTLNTAEMALTLWAINNGSYSDVPVAKALAFESEFLSFVRTQHP
EVLEAVNASGAMSDESEKTLEAAMKSFKSSYAYQA
>Mature_515_residues
MQLNPAEISDLIKAKIENLSVNAEVRTRGTVISVTDGIVRIHGLSDAMQGEMLEFPGNTFGLAMNLERDSVGAVVLGEYE
HIKEGDTVTCTGRILEVPVGRELVGRVVDALGRPIDGKGPINTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVG
RGQRELIIGDRQTGKTAVALDAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAMEHTIVVAATASEAAALQYIAPY
SGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEHEVEKLTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGGIRLALAQY
RELAAFSQFASDLDEATRKQLEHGEVVTELMKQKQFSTLNTAEMALTLWAINNGSYSDVPVAKALAFESEFLSFVRTQHP
EVLEAVNASGAMSDESEKTLEAAMKSFKSSYAYQA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=514, Percent_Identity=55.8365758754864, Blast_Score=571, Evalue=1e-163,
Organism=Homo sapiens, GI4757810, Length=514, Percent_Identity=55.8365758754864, Blast_Score=571, Evalue=1e-163,
Organism=Homo sapiens, GI19913428, Length=308, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI19913426, Length=403, Percent_Identity=27.0471464019851, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI32189394, Length=324, Percent_Identity=25.3086419753086, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI19913424, Length=263, Percent_Identity=28.1368821292776, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=69.5906432748538, Blast_Score=756, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=28.1138790035587, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1790170, Length=356, Percent_Identity=24.438202247191, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=514, Percent_Identity=54.2801556420233, Blast_Score=556, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988080, Length=514, Percent_Identity=54.2801556420233, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=514, Percent_Identity=50.3891050583658, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17510931, Length=405, Percent_Identity=28.1481481481481, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=312, Percent_Identity=29.1666666666667, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=324, Percent_Identity=24.0740740740741, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17565854, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=64, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=516, Percent_Identity=54.4573643410853, Blast_Score=570, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6319603, Length=318, Percent_Identity=29.2452830188679, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=327, Percent_Identity=26.2996941896024, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=55.4474708171206, Blast_Score=568, Evalue=1e-162,
Organism=Drosophila melanogaster, GI281361666, Length=305, Percent_Identity=27.5409836065574, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24646341, Length=305, Percent_Identity=27.5409836065574, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI17136796, Length=305, Percent_Identity=27.5409836065574, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24638766, Length=324, Percent_Identity=25.3086419753086, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583988, Length=294, Percent_Identity=30.2721088435374, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583986, Length=294, Percent_Identity=30.2721088435374, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583984, Length=294, Percent_Identity=30.2721088435374, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=23.98753894081, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583992, Length=277, Percent_Identity=29.9638989169675, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129479, Length=336, Percent_Identity=26.4880952380952, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55345; Mature: 55345

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPAEISDLIKAKIENLSVNAEVRTRGTVISVTDGIVRIHGLSDAMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCCEECEEEEECCCEEEEECCEEEEECCCHHHCCCEEECCCCEE
GLAMNLERDSVGAVVLGEYEHIKEGDTVTCTGRILEVPVGRELVGRVVDALGRPIDGKGP
EEEEEECCCCCCEEEECCHHHHCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVGRGQRELIIGDRQTGKTAVAL
CCCCEECCHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAMEHTIVVAATASEAAALQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHEECCC
SGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEHEVEKLTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAINAGISVSRVGGAAQTKVIKKLGGGIRLALAQYRELAAFSQFASDLDEATRKQ
CCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGEVVTELMKQKQFSTLNTAEMALTLWAINNGSYSDVPVAKALAFESEFLSFVRTQHP
HHHHHHHHHHHHHHHCCCCCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCH
EVLEAVNASGAMSDESEKTLEAAMKSFKSSYAYQA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQLNPAEISDLIKAKIENLSVNAEVRTRGTVISVTDGIVRIHGLSDAMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHCCEECEEEEECCCEEEEECCEEEEECCCHHHCCCEEECCCCEE
GLAMNLERDSVGAVVLGEYEHIKEGDTVTCTGRILEVPVGRELVGRVVDALGRPIDGKGP
EEEEEECCCCCCEEEECCHHHHCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVGRGQRELIIGDRQTGKTAVAL
CCCCEECCHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEEH
DAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAMEHTIVVAATASEAAALQYIAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHEECCC
SGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNEHEVEKLTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCC
NAGIRPAINAGISVSRVGGAAQTKVIKKLGGGIRLALAQYRELAAFSQFASDLDEATRKQ
CCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGEVVTELMKQKQFSTLNTAEMALTLWAINNGSYSDVPVAKALAFESEFLSFVRTQHP
HHHHHHHHHHHHHHHCCCCCHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCH
EVLEAVNASGAMSDESEKTLEAAMKSFKSSYAYQA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA