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The map label for this gene is serC [H]

Identifier: 161525432

GI number: 161525432

Start: 2476131

End: 2477213

Strand: Reverse

Name: serC [H]

Synonym: Bmul_2262

Alternate gene names: 161525432

Gene position: 2477213-2476131 (Counterclockwise)

Preceding gene: 161525433

Following gene: 161525431

Centisome position: 71.84

GC content: 66.02

Gene sequence:

>1083_bases
ATGCGCGTCTTTAATTTCTCCGCCGGCCCCGCGGCGCTGCCCGAGGAAGTGCTGCGGCAGGCCGCCGACGAAATGCTCGA
CTGGCACGGCAGCGGCATGAGCGTGATGGAGATGAGCCATCGCGGCAAGGAATTCATGTCGATCCACGAGGCGGCGCTCG
CCGACCTGCGCGAGCTGCTCGACGTGCCGGCGAGCCATCGCGTGCTGTTCCTGCAGGGCGGCGGCATCGCGGAGAACGCG
ATCGTGCCGATGAACCTGCTCGGCTCGCGCAAGACGGCCGACTTCGTCGTGACGGGCTCGTGGTCGCAGAAGTCGTTCAA
CGAGGCGAAGAAGTACTGCACGCCGCATCTCGCGGCAACCGGCAAGACGGACGCCGGCTTCACGCGCGCGCCGGCGTTCG
CCGAATGGCAGCTGTCGGACGATCCGGCCTACGTGCACCTCTGCACGAACGAGACGATCGACGGCGTCGAGACGTTCGAG
ATCCCGGATCTCGGCGACGTGCCGCTCGTCGCGGACGTGTCGTCGCACATCCTGTCGCGCCCGATGGACGTCGCGAAGTA
CGGCGTGCTGTTCGGCGGTGCGCAGAAGAACATCGGGATGGCCGGCGTGACGGTCGTGATCGTGCGCGAGGATCTGCTCG
ACCGCGCGCTGTCGATCTGCCCGTCGGCGTTCGAATGGAAGACGGTCGCCGCGAACAACTCGCTGTACAACACGCCGCCC
ACCTATGCGATCTACATCGCGGGCCTCGTGTTCCAGTGGCTGAAGCGGCAGGGCGGCCTCGGCGCGATCGAGGCGCGCAA
CATCGAAAAGGCGAAGCTGCTCTACGACACGATCGATGGGAGCAGCTTCTATCTGAACAAGGTCGAGCCGGCGGTGCGTT
CGCGCATGAACGTGCCGTTTTTCCTGGCCGACGAATCGCGCAACGAAGACTTCCTTGCCGGCGCAAAGGCGCGCGGGCTG
CTGCAGCTGAAGGGCCACAAGTCCGTCGGCGGCATGCGGGCGTCGATCTACAACGCGGTGCCGCTCGAGGGCGTGAAGGC
GCTCGTCGAGTACATGAAGGACTTCGAGCAGCGCTGCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCGAGCGCAAGCGGCCATTTCTTTTCCGGCGCGGCTCATTGGCATTGCATGACAGGCGGCAAGCCCGCCGGTCGCGT
CCCTCCCGAGGTTTTTCACG

Downstream 100 bases:

>100_bases
CGGCGGCGCGCGGCTCAAACAGCACGGCAAAACGCATGGACGACGAACTGAATTCCCGCCTGAAACCGCTGCGCGACCGC
ATCGACGCGATCGACGCGCA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELLDVPASHRVLFLQGGGIAENA
IVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYCTPHLAATGKTDAGFTRAPAFAEWQLSDDPAYVHLCTNETIDGVETFE
IPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPP
TYAIYIAGLVFQWLKRQGGLGAIEARNIEKAKLLYDTIDGSSFYLNKVEPAVRSRMNVPFFLADESRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRCA

Sequences:

>Translated_360_residues
MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELLDVPASHRVLFLQGGGIAENA
IVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYCTPHLAATGKTDAGFTRAPAFAEWQLSDDPAYVHLCTNETIDGVETFE
IPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPP
TYAIYIAGLVFQWLKRQGGLGAIEARNIEKAKLLYDTIDGSSFYLNKVEPAVRSRMNVPFFLADESRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRCA
>Mature_360_residues
MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELLDVPASHRVLFLQGGGIAENA
IVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYCTPHLAATGKTDAGFTRAPAFAEWQLSDDPAYVHLCTNETIDGVETFE
IPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPP
TYAIYIAGLVFQWLKRQGGLGAIEARNIEKAKLLYDTIDGSSFYLNKVEPAVRSRMNVPFFLADESRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRCA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=48.1994459833795, Blast_Score=342, Evalue=4e-94,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=43.6974789915966, Blast_Score=291, Evalue=5e-79,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=55.586592178771, Blast_Score=410, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=45.5801104972376, Blast_Score=331, Evalue=5e-91,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=41.1917098445596, Blast_Score=286, Evalue=3e-78,
Organism=Drosophila melanogaster, GI21356589, Length=359, Percent_Identity=49.5821727019499, Blast_Score=362, Evalue=1e-100,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39353; Mature: 39353

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELL
CEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DVPASHRVLFLQGGGIAENAIVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYCTPHLAAT
CCCCCCEEEEEECCCCCCCCEECHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCC
GKTDAGFTRAPAFAEWQLSDDPAYVHLCTNETIDGVETFEIPDLGDVPLVADVSSHILSR
CCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHC
PMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPP
CHHHHHHHHEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
TYAIYIAGLVFQWLKRQGGLGAIEARNIEKAKLLYDTIDGSSFYLNKVEPAVRSRMNVPF
HHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHEEEECCCCEEEEECCCHHHHHHCCCCE
FLADESRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRCA
EEECCCCCCCHHCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELL
CEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
DVPASHRVLFLQGGGIAENAIVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYCTPHLAAT
CCCCCCEEEEEECCCCCCCCEECHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCC
GKTDAGFTRAPAFAEWQLSDDPAYVHLCTNETIDGVETFEIPDLGDVPLVADVSSHILSR
CCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHC
PMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPP
CHHHHHHHHEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
TYAIYIAGLVFQWLKRQGGLGAIEARNIEKAKLLYDTIDGSSFYLNKVEPAVRSRMNVPF
HHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHEEEECCCCEEEEECCCHHHHHHCCCCE
FLADESRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRCA
EEECCCCCCCHHCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA